Tobacco UseNCT06605924
Oral Nicotine Pouch Marketing Features Influence on Perceptions
A study testing Tobacco-free, Discrete and Convenient in people with Tobacco Use, run by Johns Hopkins Bloomberg School of Public Health at 1 site in United States.
Trial summary
This study tests the effects of three oral nicotine marketing features on product perceptions. Read more about this study
- Who is it for?
- Ages 13 to 120 yearsHealthy volunteers can take part
- Conditions the study is for
- Tobacco Use
- What is being tested?
- Tobacco-free, Discrete and Convenient
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 5,133 participants
- Where
- 1 siteUnited States
- Study dates
- 12 May 2025to 18 Nov 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 13 to 120 years
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
- Live in the US
- For youth age <21: Never used any nicotine pouch
- For adults: Smoked greater than or equal to 100 cigarettes in during lifetime
- For adults: Currently smoke some or all days
- For adults: No regular use of oral nicotine pouches
- For adults: No past 30-day pouch use
Who cannot join
- Do not live in the US
- For youth age <21: Ever used nicotine pouches
- For youth age <21: Greater than or equal to 100 lifetime uses of any other nicotine or tobacco product
- For adults: Smoked <100 cigarettes in life
- For adults: Does not currently smoke some or all days
- For adults: Regular use of oral nicotine pouches
- For adults: Past 30-day pouch use
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Aim 2 Study - Novel "Tobacco-Free" Oral Nicotine Pouches: The Impact of Product Features and Marketing Influences on Abuse Liability, Perceptions, and Use Behavior in Smokers and Non-Nicotine Users
This study tests the effects of three oral nicotine marketing features on product perceptions.
- Conditions
- Tobacco Use
- Being tested
- Tobacco-free, Discrete, Convenient
- Medical subject headings
- Tobacco Use
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Tobacco-freeOther
Ad contains baseline language + language that product is tobacco-free
DiscreteOther
Ad contains baseline language + language that product is discrete
ConvenientOther
Ad contains baseline language + language that product is convenient
| Study group | Role | What they receive |
|---|---|---|
| Tobacco-free | Experimental | Viewing a static advertisement Receives: Other: Tobacco-free |
| Discrete | Experimental | Viewing a static advertisement Receives: Other: Discrete |
| Convenient | Experimental | Viewing a static advertisement Receives: Other: Convenient |
| Control | No intervention | Viewing a static advertisement - baseline language only |
What is being measured
The primary outcome is the main question the study is designed to answer.
Absolute perceived harm
How harmful participant perceives the product to be. Participants will answer a survey item, How harmful do you think this product is to your health; with response options ranging from 0-Not at all harmful to 4-Extremely harmful.
Measured: Immediately after viewing ad
Relative perceived harm
How harmful participant perceives the product to be, relative to other tobacco products. Participants will answer a survey item, Compared to the following products [cigarettes; little cigars/cigarillos/filtered cigars; e-cigarettes; smokeless tobacco; heated tobacco; alcohol; cannabis], how harmful do you think the advertised product is? with response options ranging from 0-a lot less harmful to 4-a lot more harmful.
Measured: Immediately after viewing ad
Absolute perceived addictiveness
How addictive participant perceives the product to be. Participants will answer a survey item, How addictive do you think this product is; with response options ranging from 0-not at all addictive to 4-extremely addictive.
Measured: Immediately after viewing ad
Relative perceived addictiveness
How addictive participant perceives the product to be, relative to other tobacco products. Participants will answer a survey item; Compared to the following products [cigarettes; little cigars/cigarillos/filtered cigars; e-cigarettes; smokeless tobacco; heated tobacco products; alcohol; cannabis], how addictive do you think the advertised product is; with response options ranging from 0-a lot less addictive to 4-a lot more addictive.
Measured: Immediately after viewing ad
Product appeal
How appealing participant perceives the product to be. Participants will answer a survey item to indicate how much they agree or disagree with the statement, I am curious about the product in the ad;, with response options from 0-strongly disagree to 4-strongly agree.
Measured: Immediately after viewing ad
Use intention
Perceived likelihood of using the product. Participants will answer a survey item to indicate how much they agree or disagree with the statement, I am interested in using the product in the ad, with response options from 0-strongly disagree to 4-strongly agree.
Measured: Immediately after viewing ad
Secondary outcomes (2)
Perceived ability to satisfy nicotine cravings
Perceived ability of the product to satisfy one's nicotine carvings. Participants will answer a survey item to indicate how much they agree or disagree with the statement; The product in the ad would satisfy nicotine cravings, with response options from 0-strongly disagree to 4-strongly agree.
Measured: Immediately after viewing ad
Perceived ability to help one quit smoking
Perceived ability of the product to help one quit smoking cigarettes. Participants will answer a survey item to indicate how much they agree or disagree with the statement;The product in the ad would help with quitting smoking;, with response options from 0-strongly disagree to 4-strongly agree.
Measured: Immediately after viewing ad
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 Sep 2024
- Study start12 May 2025
- Primary completion18 Nov 2025
- Study completion18 Nov 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Tobacco UseStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Model description
- Participants will view ads in each of four conditions manipulating presence of different marketing features.
- Masking
- None (open label)
- Enrolment
- 5,133 participants (actual)
Sponsor and investigators
- Lead sponsor
- Johns Hopkins Bloomberg School of Public Health
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute on Drug Abuse (NIDA)
- Responsible party
- Sponsor
- Investigators
- Meghan Moran, PhD, Principal investigator, Johns Hopkins University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06605924
- Sponsor's protocol ID
- IRB00029102
- Other IDs
- R01DA055962
- Status last verified
- Jul 2026
- First submitted
- 18 Sep 2024
- Last updated
- 23 Jul 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 23 Jul 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Aim 2 Study - Novel "Tobacco-Free" Oral Nicotine Pouches: The Impact of Product Features and Marketing Influences on Abuse Liability, Perceptions, and Use Behavior in Smokers and Non-Nicotine Users
- ClinicalTrials.gov ID
- NCT06605924
- Acronym / sponsor ID
- IRB00029102
- Conditions
- Tobacco Use
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 5,133 participants (actual)
- Lead sponsor
- Johns Hopkins Bloomberg School of Public HealthUniversity, hospital or other
- Collaborators
- National Institute on Drug Abuse (NIDA)
- Study start
- 12 May 2025 (actual)
- Primary completion
- 18 Nov 2025 (actual)
- Study completion
- 18 Nov 2025 (actual)
- First posted
- 20 Sep 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study tests the effects of three oral nicotine marketing features on product perceptions.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 4
- Model description
- Participants will view ads in each of four conditions manipulating presence of different marketing features.
| Arm | Type | Receives |
|---|---|---|
| Tobacco-free | Experimental | Other: Tobacco-freeViewing a static advertisement |
| Discrete | Experimental | Other: DiscreteViewing a static advertisement |
| Convenient | Experimental | Other: ConvenientViewing a static advertisement |
| Control | No intervention | –Viewing a static advertisement - baseline language only |
Who may qualify
- Ages
- 13 to 120 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (6 listed)
- Live in the US
- For youth age <21: Never used any nicotine pouch
- For adults: Smoked greater than or equal to 100 cigarettes in during lifetime
- For adults: Currently smoke some or all days
- For adults: No regular use of oral nicotine pouches
Key exclusion criteria (7 listed)
- Do not live in the US
- For youth age <21: Ever used nicotine pouches
- For youth age <21: Greater than or equal to 100 lifetime uses of any other nicotine or tobacco product
- For adults: Smoked <100 cigarettes in life
- For adults: Does not currently smoke some or all days
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Tobacco-freeAd contains baseline language + language that product is tobacco-free | Other | Tobacco-free |
| DiscreteAd contains baseline language + language that product is discrete | Other | Discrete |
| ConvenientAd contains baseline language + language that product is convenient | Other | Convenient |
Primary outcome
Absolute perceived harm
Time frame: Immediately after viewing ad
How harmful participant perceives the product to be. Participants will answer a survey item, How harmful do you think this product is to your health; with response options ranging from 0-Not at all harmful to 4-Extremely harmful.
Relative perceived harm
Time frame: Immediately after viewing ad
How harmful participant perceives the product to be, relative to other tobacco products. Participants will answer a survey item, Compared to the following products [cigarettes; little cigars/cigarillos/filtered cigars; e-cigarettes; smokeless tobacco; heated tobacco; alcohol; cannabis], how harmful do you think the advertised product is? with response options ranging from 0-a lot less harmful to 4-a lot more harmful.
Absolute perceived addictiveness
Time frame: Immediately after viewing ad
How addictive participant perceives the product to be. Participants will answer a survey item, How addictive do you think this product is; with response options ranging from 0-not at all addictive to 4-extremely addictive.
Relative perceived addictiveness
Time frame: Immediately after viewing ad
How addictive participant perceives the product to be, relative to other tobacco products. Participants will answer a survey item; Compared to the following products [cigarettes; little cigars/cigarillos/filtered cigars; e-cigarettes; smokeless tobacco; heated tobacco products; alcohol; cannabis], how addictive do you think the advertised product is; with response options ranging from 0-a lot less addictive to 4-a lot more addictive.
Product appeal
Time frame: Immediately after viewing ad
How appealing participant perceives the product to be. Participants will answer a survey item to indicate how much they agree or disagree with the statement, I am curious about the product in the ad;, with response options from 0-strongly disagree to 4-strongly agree.
Use intention
Time frame: Immediately after viewing ad
Perceived likelihood of using the product. Participants will answer a survey item to indicate how much they agree or disagree with the statement, I am interested in using the product in the ad, with response options from 0-strongly disagree to 4-strongly agree.
2 secondary outcomes
Perceived ability to satisfy nicotine cravings
Time frame: Immediately after viewing ad
Perceived ability to help one quit smoking
Time frame: Immediately after viewing ad
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Jul 2026.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Meghan Moran, PhD principal investigator
Johns Hopkins University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Tobacco-free, Discrete and Convenient in people with Tobacco Use, run by Johns Hopkins Bloomberg School of Public Health at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 23 Jul 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Absolute perceived harm (time frame: Immediately after viewing ad). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Jul 2026.