HealthyNCT06607354
Consuming Grass Finished Lamb Improves Blood Plasma ω-3 Fatty Acid Response Among Healthy Consumers.
A study testing Grass fed lamb in people with Healthy, run by Queen's University, Belfast at 1 site in United Kingdom.
Trial summary
This study will investigate the impact of consuming grass-finished lamb meat on blood omega-3 PUFAs and cardiovascular risk factors compared to concentrate-finished lamb meat. Healthy volunteers will consume three portions of lamb meat/week from a grass-finished meat treatment or a concentrate-finished meat treatment… Read more about this study
- Who is it for?
- Ages 18 to 64 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy
- What is being tested?
- Grass fed lamb
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 34 participants
- Where
- 1 siteUnited Kingdom
- Study dates
- 20 Jun 2019to 13 Dec 2019
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 64 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Healthy male and female volunteers aged between 18-64 years old.
Who cannot join
- Participants with a BMI of <18.5 km/m² and greater than >35 km/m².
- Participants who take prescribed medication, including statins to reduce LDL cholesterol, and any form of dietary supplements (excluding vitamin D).
- People who smoke.
- Participants who consume more than two portions of fish per month.
Trial locations and contacts
1 site in 1 country.
United Kingdom1 site
School of Biological Sciences, Queen's University Belfast
Belfast, BT9 5DL
About this study
Official title: The Effect of Consuming Grass Finished Lamb Meat on Omega-3 Blood Response Among Healthy Consumers
This study will investigate the impact of consuming grass-finished lamb meat on blood omega-3 PUFAs and cardiovascular risk factors compared to concentrate-finished lamb meat. Healthy volunteers will consume three portions of lamb meat/week from a grass-finished meat treatment or a concentrate-finished meat treatment for four weeks. Blood samples will be taken at weeks zero and four. The primary outcome is to assess difference in change in omega-3 PUFA concentration in plasma and platelets between treatment groups. The secondary outcome is to assess between groups differences in change in cardiovascular disease risk factors including blood pressure, BMI and lipids among healthy individuals.
- Conditions
- Healthy
- Being tested
- Grass fed lamb
- Keywords
- Lamb, Omega-3, Fatty acids, Plasma, Plasma phospholipids
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Grass fed lambOther
This study investigated the impact of consuming grass finished lamb on total blood plasma and blood plasma phospholipids (PL) FA and on cardiovascular risk factors, including heart rate, blood pressure (BP), HDL-cholesterol, LDL-cholesterol, and TAG cholesterol, in humans.
| Study group | Role | What they receive |
|---|---|---|
| Concentrate/ Cereal fed lamb | No intervention | Participants to consume three portions of lamb per week for four consecutive weeks. The lamb diet was a concentrate/cereal pellet. |
| Grass fed lamb | Experimental | Participants to consume three portions of lamb per week for four consecutive weeks. The lamb diet was grass only. Receives: Other: Grass fed lamb |
What is being measured
The primary outcome is the main question the study is designed to answer.
Fatty acid (%) change in blood plasma between treatments
Primary outcome is to assess the impact of consuming grass vs concentrate finished lamb on blood plasma response in healthy volunteers
Measured: Week 0 and week 4
Fatty acid change (%) in blood plasma phospholipids between treatments
Primary outcome is to assess the impact of consuming grass vs concentrate finished lamb on blood plasma phospholipid response in healthy volunteers
Measured: Week 0 and week 4
Secondary outcomes (4)
Change in weight (kg) in participants between treatments
Secondary outcome is to assess the impact of consuming grass vs concentrate finished lamb on weight among healthy volunteers
Measured: Week 0 and week 4
Change in Body Mass Index (BMI) in participants between treatments - calculated by dividing weight (kg) by height in meters squared
Secondary outcome is to assess the impact of consuming grass vs concentrate finished lamb on weight and BMI response in healthy volunteers
Measured: Week 0 and week 4
Cholesterol
Secondary outcome is to assess the impact of consuming grass vs concentrate finished lamb on total cholesterol, LDL, HDL and TAG response in healthy volunteers
Measured: Week 0 and week 4
Blood pressure (diastolic and systolic)
Secondary outcome is to assess the impact of consuming grass vs concentrate finished lamb on blood pressure (diastolic and systolic) response in healthy volunteers
Measured: Week 0 and week 4
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 Sep 2024
- Study start20 Jun 2019
- Primary completion13 Dec 2019
- Study completion13 Dec 2019
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for HealthyStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Describe parallel arms
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 34 participants (actual)
Sponsor and investigators
- Lead sponsor
- Queen's University, Belfast
- Sponsor type
- University, hospital or other
- Collaborators
- Agri-Food and Biosciences Institute
- Responsible party
- Principal investigator, Lynda Perkins, Queen's University, Belfast
- Investigators
- Nigel D Scollan, PhD, Principal investigator, Queen's University, BelfastJayne V Woodside, PhD, Principal investigator, Queen's University, Belfast
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06607354
- Sponsor's protocol ID
- 19.08v2
- Status last verified
- Sep 2024
- First submitted
- 9 Sep 2024
- Last updated
- 24 Sep 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Perkins LS, Nugent AP, Woodside JV, Cardwell CR, Scollan ND. Consuming grass finished lamb improves blood plasma omega-3 fatty acid response among healthy consumers. Eur J Nutr. 2025 Jul 21;64(5):242. doi: 10.1007/s00394-025-03765-z.
PubMed 40690019
Study at a glance
From the registry record, last updated by the sponsor on 24 Sep 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effect of Consuming Grass Finished Lamb Meat on Omega-3 Blood Response Among Healthy Consumers
- ClinicalTrials.gov ID
- NCT06607354
- Acronym / sponsor ID
- 19.08v2
- Conditions
- Healthy
- Keywords
- Lamb, Omega-3, Fatty acids, Plasma, Plasma phospholipids
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 34 participants (actual)
- Lead sponsor
- Queen's University, BelfastUniversity, hospital or other
- Collaborators
- Agri-Food and Biosciences Institute
- Study start
- 20 Jun 2019 (actual)
- Primary completion
- 13 Dec 2019 (actual)
- Study completion
- 13 Dec 2019 (actual)
- First posted
- 23 Sep 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will investigate the impact of consuming grass-finished lamb meat on blood omega-3 PUFAs and cardiovascular risk factors compared to concentrate-finished lamb meat. Healthy volunteers will consume three portions of lamb meat/week from a grass-finished meat treatment or a concentrate-finished meat treatment for four weeks. Blood samples will be taken at weeks zero and four. The primary outcome is to assess difference in change in omega-3 PUFA concentration in plasma and platelets between treatment groups. The secondary outcome is to assess between groups differences in change in cardiovascular disease risk factors including blood pressure, BMI and lipids among healthy individuals.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
- Model description
- Describe parallel arms
| Arm | Type | Receives |
|---|---|---|
| Concentrate/ Cereal fed lamb | No intervention | –Participants to consume three portions of lamb per week for four consecutive weeks. The lamb diet was a concentrate/cereal pellet. |
| Grass fed lamb | Experimental | Other: Grass fed lambParticipants to consume three portions of lamb per week for four consecutive weeks. The lamb diet was grass only. |
Who may qualify
- Ages
- 18 to 64 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (1 listed)
- Healthy male and female volunteers aged between 18-64 years old.
Key exclusion criteria (4 listed)
- Participants with a BMI of <18.5 km/m² and greater than >35 km/m².
- Participants who take prescribed medication, including statins to reduce LDL cholesterol, and any form of dietary supplements (excluding vitamin D).
- People who smoke.
- Participants who consume more than two portions of fish per month.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Grass fed lambThis study investigated the impact of consuming grass finished lamb on total blood plasma and blood plasma phospholipids (PL) FA and on cardiovascular risk factors, including heart rate, blood pressure (BP), HDL-cholesterol, LDL-cholesterol, and TAG cholesterol, in humans. | Other | Grass fed lamb |
Primary outcome
Fatty acid (%) change in blood plasma between treatments
Time frame: Week 0 and week 4
Primary outcome is to assess the impact of consuming grass vs concentrate finished lamb on blood plasma response in healthy volunteers
Fatty acid change (%) in blood plasma phospholipids between treatments
Time frame: Week 0 and week 4
Primary outcome is to assess the impact of consuming grass vs concentrate finished lamb on blood plasma phospholipid response in healthy volunteers
4 secondary outcomes
Change in weight (kg) in participants between treatments
Time frame: Week 0 and week 4
Change in Body Mass Index (BMI) in participants between treatments - calculated by dividing weight (kg) by height in meters squared
Time frame: Week 0 and week 4
Cholesterol
Time frame: Week 0 and week 4
Blood pressure (diastolic and systolic)
Time frame: Week 0 and week 4
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 24 Sep 2024.
- Derived from this study: PubMed 40690019Perkins LS, Nugent AP, Woodside JV, Cardwell CR, Scollan ND. Consuming grass finished lamb improves blood plasma omega-3 fatty acid response among healthy consumers. Eur J Nutr. 2025 Jul 21;64(5):242. doi: 10.1007/s00394-025-03765-z.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Nigel D Scollan, PhD principal investigator
Queen's University, Belfast
Jayne V Woodside, PhD principal investigator
Queen's University, Belfast
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Grass fed lamb in people with Healthy, run by Queen's University, Belfast at 1 site in United Kingdom.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 24 Sep 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United Kingdom. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Fatty acid (%) change in blood plasma between treatments (time frame: Week 0 and week 4). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06607354, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 24 Sep 2024.