Anger ProblemsCARTNCT06609330
Treatment of Chronic Anger and Aggression Following Military-Related Betrayal
A study testing Countering Chronic Anger and Aggression Related to Trauma and Transgressions (CART) in people with Anger Problems and Aggression, run by The University of Texas Health Science Center at San Antonio at 1 site in United States.
Trial summary
The goal of this clinical trial is to learn if a treatment designed to deal with anger and aggression from a past betrayal will work. The study will be done on active duty military service members and veterans aged 18 or older. Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Anger Problems, Aggression
- What is being tested?
- Countering Chronic Anger and Aggression Related to Trauma and Transgressions (CART)
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteUnited States
- Study dates
- 17 Mar 2025to Jan 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- Adult active duty military service members and veterans aged 18 or older.
- Endorses a history of military-related betrayal (on the Modified Moral Injury Questionnaire)
- Endorses problematic anger in the past month (as evidenced by a score of 12 or above on the Dimensions of Anger Reactions; DAR-5)
- Engaged in at least 1 self-reported act of aggression in the past 1 month (on the Overt Aggression Scale-Modified; OAS-M)
Who cannot join
- Participated in an anger management or trauma-focused intervention within the past 3 months as assessed by self-report.
- Acute suicidality requiring immediate intervention, such as hospitalization as assessed by the Depressive Symptoms Index-Suicidality Subscale (DSI-SS) combined with follow up clinical interview for elevated scores.
- Is currently homicidal with plans and intent to hurt a specific person and requiring immediate intervention as measured by self-report and follow-up with clinician if screened positive.
- Moderate to severe brain injury as measured by inability to comprehend the informed consent document or baseline assessments.
- Has severe alcohol consumption patterns as evidenced by a score of 19 or above on the Alcohol Use Disorders Identification Test (AUDIT).
- Experiencing active psychosis or mania as measured by the Prodromal Questionnaire-Brief Version and the Mood Disorders Questionnaire.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Carl R. Darnall Army Medical Center (CRDAMC) at Fort Cavazos
Fort Cavazos, Texas, 76554
Vanessa Jacoby, PhD, 254-289-3468, jacobyv@uthscsa.edu
About this study
Official title: Assessment and Treatment of Chronic Anger and Aggression Following Military-Related Interpersonal and Institutional Betrayal: A Pilot Investigation
The goal of this clinical trial is to learn if a treatment designed to deal with anger and aggression from a past betrayal will work. The study will be done on active duty military service members and veterans aged 18 or older. The main questions it aims to answer are:
- Will participants be satisfied with the treatment, and is the treatment feasible to do in a military outpatient setting
- Will the treatment help with anger and aggression issues.
Read more
Researchers will compare differences in groups that have different wait times (2-, 3-, or 4-weeks).
Participants will complete surveys before, during and after the treatment. The treatment will be 14 modules given twice a week. About 1 month after treatment ends, surveys will be taken again.
Read the detailed description
Participants will undergo the study procedures described below. The preferred method of assessment and treatment is face-to-face in the STRONG STAR offices at Fort Cavazos. However, there may be circumstances when participants can complete the treatment through telebehavioral health (i.e., by phone or using a HIPAA-compliant video calling platform like Zoom). Decisions will be made on a case-by-case basis as issues arise for individuals (e.g., childcare) and in discussion with the treatment team. If participants do not have internet access they may need to complete assessments in person at the STRONG STAR office or by phone.
- During the wait time:
- Complete a 5-10 minute assessment twice per week (Monday/Thursday or Tuesday/Friday) to assess level of anger, aggression, and interactions with others since last assessment.
- The assigned therapist will call participants once a week for a 10-minute, check-in.
- At the end of participants' assigned wait time, they will complete an assessment of level of anger, aggression, interactions with others, mental, and physical health.
- During treatment:
- Begin treatment within 1 week of last wait time assessment.
- Participate in 7-24 (average 14) one-hour bi-weekly (Monday/Thursday or Tuesday/Friday) CART sessions.
- Prior to each session, participants will complete the same 5-10 minute assessment to assess level of anger, aggression, and interactions with others since last assessment.
- At the final treatment session, participants will be scheduled to complete a 1-month follow-up assessment.
- For follow-up:
- Complete a 1-month follow up assessment between 4-8 weeks after the final treatment session.
- Participants will be sent a link to complete the follow-up assessment.
- Complete the same questionnaires completed at pre-treatment plus an exit interview and a brief satisfaction survey.
- Conditions
- Anger Problems, Aggression
- Being tested
- Countering Chronic Anger and Aggression Related to Trauma and Transgressions (CART)
- Keywords
- Anger management, Military-related betrayal, Deficit of trust
- Medical subject headings
- Aggression
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Countering Chronic Anger and Aggression Related to Trauma and Transgressions (CART)Behavioural
Also called CART
Countering Chronic Anger and Aggression Related to Trauma and Transgressions (CART), a novel intervention for reducing chronic anger and aggression and improving interpersonal relationships, in military personnel who have experienced military-related betrayal delivered in 14 treatment modules twice a week.
| Study group | Role | What they receive |
|---|---|---|
| 2-week wait time group | Experimental | This group is randomized to a 2-week wait time prior to treatment with CART Receives: Behavioral: Countering Chronic Anger and Aggression Related to Trauma and Transgressions (CART) |
| 3-week wait time group | Experimental | This group is randomized to a 3-week wait time prior to treatment with CART Receives: Behavioral: Countering Chronic Anger and Aggression Related to Trauma and Transgressions (CART) |
| 4-week wait time group | Experimental | This group is randomized to a 4-week wait time prior to treatment with CART Receives: Behavioral: Countering Chronic Anger and Aggression Related to Trauma and Transgressions (CART) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Successful recruitment
Number of eligible referrals that are recruited, enrolled into the study and randomized to treatment
Measured: Study start to last subject enrolled, approximately 1 year
Client satisfaction survey (CSQ-8)
The survey will assess participant acceptability using the CSQ-8, an 8-item self-report measure designed to assess client satisfaction. Each question is answered on a 4-point scale with a possible range of scores between 8-32. A higher score indicates a higher level of overall satisfaction. Mean scores will be used to determine participant satisfaction.
Measured: 1 month after study end ( at approximately 11-18 weeks)
Overt Aggression Scale-Modified (OAS-M)
A 17-item measure that assesses frequency of different aggression acts in outpatient settings, including verbal and physical aggression against self, other, and objects. The OAS-M is scored by summing the instances of aggression since the last assessment. The OAS-M had been administered as an interview as well as self-report and will be administered as a self-report in this study, consistent with past aggression research with veterans (Miles, Kent et al., 2020). The score is calculated using a sum total of all instances of aggression. Higher scores indicate a greater frequency of aggressive behaviors.
Measured: Baseline to 1 month post treatment (approximately 11-18 weeks)
Inventory of Interpersonal Problems-Short Version (IIP-32)
A 32-item self-report assessment designed to measure interpersonal functioning. Items are scored on a five-point scale from 0 (not at all) to 4 (extremely) in response to the stem: "How much have you been distressed by this problem?" There are 8 factors and a total score. The 8 factors are: hard to be assertive, hard to be sociable, hard to be supportive, too dependent, too caring, too aggressive, hard to be involved and too open. The possible total score ranges from a T-score are 0-100. T-scores that are higher than 60 are above average and T-scores 70 or higher suggest significant interpersonal difficulty.
Measured: Baseline to 1 month post treatment (approximately 11-18 weeks)
State Trait Anger Expression Inventory-2 (STAXI-2)
A 57-item inventory which measures the frequency and intensity of anger as an emotional state. There are 6 scales, 5 subscales, and an Anger Expression Index (total anger expression). The State Anger scale (15 items) measures anger intensity as a momentary emotional state, while the Trait Anger scale (10 items) measures the disposition to experience angry feelings as a personality-like trait over lengthy time periods (i.e., the individual's disposition to become angry or angry temperament). The Anger Expression scale (16 items) and the Anger Control scale (16 items) measure four anger-related trait dimensions. Ratings of items are on a 4-point response scales that measure state anger (intensity) as well as trait anger (frequency). The possible total range is a T-score from 0 to 100. Individuals with anger scores higher than the 75-percentile experience and/ or express angry feelings to a degree that may interfere with optimal functioning.
Measured: Baseline to 1 month post treatment (approximately 11-18 weeks)
Secondary outcomes (6)
Rate of protocol completion
The 14 modules may be completed within a 7-14 week time period by each participant.
Measured: Treatment end (Approximately 7-14 weeks)
Number of modules completed
A count of how many of the 14 modules are completed
Measured: Baseline to end of treatment (approximately 7-14 weeks)
Brief Inventory of Psychosocial Functioning (B-IPF)
A 7-item, self-report measures of psychosocial functioning in seven life domains: romantic relationship, relationship with children, family relationships, friendships and socializing, work, training and education, and activities of daily living. In each area on a 7-point scale ranging from 0 = Not at all to 6 = Very much. The B-IPF total score is calculated by summing the scale items completed by the respondent, dividing by the maximum possible score based upon the number of applicable items and multiplying by 100. Higher scores indicate greater psychosocial dysfunction.
Measured: Baseline to 1 month post treatment (approximately 11-18 weeks)
Dimensions of Anger Reactions (DAR-5)
A 5-item self report measure that assesses anger frequency, intensity, urge to act aggressively and impact on social functioning over the past 1 month. Respondents are asked how impacted they have been on a five-point Likert scale ranging from 0-5. Items are summed to provide a total severity score (range 5-25). A score of 12 or higher indicates problematic anger.
Measured: Baseline to 1 month post treatment (approximately 11-18 weeks)
Revised Conflict Tactics Scale Short Form (CTS-2)
The CTS-2 poses 39 questions to assess five tactics used when conflict occurs within the relationships of dating, cohabitating, or marital couples. For this study, only the Physical Assault and Psychological Aggression subscales (20 items) of the CTS-2 will be used, broadening the assessment of conflict to query interpersonal conflict among friends, colleagues, and acquaintances as well as the family. The scoring range is: 0-6, Two Subscales: 1) Psychological Aggression: 1-8 2) Physical Assault: 9-20, Special Coding: Sum midpoints of chosen response option: Never-0, Once-1, Twice-2, 3-5 times -4 , 6-10 times-8, 11-20 times-15, greater than 20 times-25. For item scoring range 0-25, Psychological Aggression scoring range 0-200, Physical Assault scoring range 0-300. The higher scores indicate higher levels of Psychological Aggression and Physical Assault.
Measured: Baseline to 1 month post treatment (approximately 11-18 weeks)
Trauma-Related Anger Scale (TRAS)
A 19-item self report measure to assess anger in the context of posttraumatic stress. Participants are asked to rate each item from Not at all true (0) to ;Definitely True(3) both prior to their traumatic event, and within the past two weeks. The scoring range for the items summed to provide a total severity score is 0-57. Items 1-7 = Anger giving a sense of control or energy, Items 8-14 = thought and emotional avoidance relating to anger, Items 15-17 = anger in response to threat, Items 18-19 = anger in response to pity. The higher score means greater anger in the context of PTSD. Higher scores in past two weeks, as compared with pre-trauma scores, indicate more severe trauma-related anger.
Measured: Baseline to 1 month post treatment (approximately 11-18 weeks)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Sep 2024
- Study start17 Mar 2025
- Primary completionNov 2026 (estimated)
- Study completionJan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Anger ProblemsStudies of the same condition, open and under way.
- More trials run by The University of Texas Health Science Center at San AntonioThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Upon enrollment into the study, participants will begin with a minimal contact wait condition followed by randomization to different wait times (2-, 3-, or 4-weeks)
- Masking
- None (open label)
- Enrolment
- 40 participants (estimated)
Sponsor and investigators
- Sponsor type
- University, hospital or other
- Collaborators
- United States Department of Defense
- Responsible party
- Principal investigator, Vanessa Jacoby, The University of Texas Health Science Center at San Antonio
- Investigators
- Vanessa Jacoby, PhD, Principal investigator, The University of Texas Health Science Center at San AntonioAlan Peterson, PhD, Principal investigator, The University of Texas Health Science Center at San Antonio
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06609330
- Sponsor's protocol ID
- 20230329HU
- Other IDs
- W81XWH-22-2-0085
- Acronym
- CART
- Status last verified
- Mar 2026
- First submitted
- 14 Aug 2024
- Last updated
- 1 Apr 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: At the conclusion of the study all data will be stripped of identifiers. De-identified (anonymized) data will be maintained indefinitely in the STRONG STAR Repository. Identifiable data from participants who signed the consent to have their data placed in the STRONG STAR Repository will be maintained under the UTHSCSA IRB-approved Repository protocol indefinitely.
Study at a glance
From the registry record, last updated by the sponsor on 1 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Assessment and Treatment of Chronic Anger and Aggression Following Military-Related Interpersonal and Institutional Betrayal: A Pilot Investigation
- ClinicalTrials.gov ID
- NCT06609330
- Acronym / sponsor ID
- CART / 20230329HU
- Conditions
- Anger Problems, Aggression
- Keywords
- Anger management, Military-related betrayal, Deficit of trust
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 40 participants (estimated)
- Lead sponsor
- The University of Texas Health Science Center at San AntonioUniversity, hospital or other
- Collaborators
- United States Department of Defense
- Study start
- 17 Mar 2025 (actual)
- Primary completion
- Nov 2026 (estimated)
- Study completion
- Jan 2027 (estimated)
- First posted
- 24 Sep 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to learn if a treatment designed to deal with anger and aggression from a past betrayal will work. The study will be done on active duty military service members and veterans aged 18 or older. The main questions it aims to answer are:
- Will participants be satisfied with the treatment, and is the treatment feasible to do in a military outpatient setting
- Will the treatment help with anger and aggression issues.
Researchers will compare differences in groups that have different wait times (2-, 3-, or 4-weeks).
Participants will complete surveys before, during and after the treatment. The treatment will be 14 modules given twice a week. About 1 month after treatment ends, surveys will be taken again.
Detailed description
Participants will undergo the study procedures described below. The preferred method of assessment and treatment is face-to-face in the STRONG STAR offices at Fort Cavazos. However, there may be circumstances when participants can complete the treatment through telebehavioral health (i.e., by phone or using a HIPAA-compliant video calling platform like Zoom). Decisions will be made on a case-by-case basis as issues arise for individuals (e.g., childcare) and in discussion with the treatment team. If participants do not have internet access they may need to complete assessments in person at the STRONG STAR office or by phone.
- During the wait time:
- Complete a 5-10 minute assessment twice per week (Monday/Thursday or Tuesday/Friday) to assess level of anger, aggression, and interactions with others since last assessment.
- The assigned therapist will call participants once a week for a 10-minute, check-in.
- At the end of participants' assigned wait time, they will complete an assessment of level of anger, aggression, interactions with others, mental, and physical health.
- During treatment:
- Begin treatment within 1 week of last wait time assessment.
- Participate in 7-24 (average 14) one-hour bi-weekly (Monday/Thursday or Tuesday/Friday) CART sessions.
- Prior to each session, participants will complete the same 5-10 minute assessment to assess level of anger, aggression, and interactions with others since last assessment.
- At the final treatment session, participants will be scheduled to complete a 1-month follow-up assessment.
- For follow-up:
- Complete a 1-month follow up assessment between 4-8 weeks after the final treatment session.
- Participants will be sent a link to complete the follow-up assessment.
- Complete the same questionnaires completed at pre-treatment plus an exit interview and a brief satisfaction survey.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
- Model description
- Upon enrollment into the study, participants will begin with a minimal contact wait condition followed by randomization to different wait times (2-, 3-, or 4-weeks)
| Arm | Type | Receives |
|---|---|---|
| 2-week wait time group | Experimental | Behavioral: Countering Chronic Anger and Aggression Related to Trauma and Transgressions (CART)This group is randomized to a 2-week wait time prior to treatment with CART |
| 3-week wait time group | Experimental | Behavioral: Countering Chronic Anger and Aggression Related to Trauma and Transgressions (CART)This group is randomized to a 3-week wait time prior to treatment with CART |
| 4-week wait time group | Experimental | Behavioral: Countering Chronic Anger and Aggression Related to Trauma and Transgressions (CART)This group is randomized to a 4-week wait time prior to treatment with CART |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Adult active duty military service members and veterans aged 18 or older.
- Endorses a history of military-related betrayal (on the Modified Moral Injury Questionnaire)
- Endorses problematic anger in the past month (as evidenced by a score of 12 or above on the Dimensions of Anger Reactions; DAR-5)
- Engaged in at least 1 self-reported act of aggression in the past 1 month (on the Overt Aggression Scale-Modified; OAS-M)
Key exclusion criteria (6 listed)
- Participated in an anger management or trauma-focused intervention within the past 3 months as assessed by self-report.
- Acute suicidality requiring immediate intervention, such as hospitalization as assessed by the Depressive Symptoms Index-Suicidality Subscale (DSI-SS) combined with follow up clinical interview for elevated scores.
- Is currently homicidal with plans and intent to hurt a specific person and requiring immediate intervention as measured by self-report and follow-up with clinician if screened positive.
- Moderate to severe brain injury as measured by inability to comprehend the informed consent document or baseline assessments.
- Has severe alcohol consumption patterns as evidenced by a score of 19 or above on the Alcohol Use Disorders Identification Test (AUDIT).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Countering Chronic Anger and Aggression Related to Trauma and Transgressions (CART)Also: CARTCountering Chronic Anger and Aggression Related to Trauma and Transgressions (CART), a novel intervention for reducing chronic anger and aggression and improving interpersonal relationships, in military personnel who have experienced military-related betrayal delivered in 14 treatment modules twice a week. | Behavioural | 2-week wait time group, 3-week wait time group, 4-week wait time group |
Primary outcome
Successful recruitment
Time frame: Study start to last subject enrolled, approximately 1 year
Number of eligible referrals that are recruited, enrolled into the study and randomized to treatment
Client satisfaction survey (CSQ-8)
Time frame: 1 month after study end ( at approximately 11-18 weeks)
The survey will assess participant acceptability using the CSQ-8, an 8-item self-report measure designed to assess client satisfaction. Each question is answered on a 4-point scale with a possible range of scores between 8-32. A higher score indicates a higher level of overall satisfaction. Mean scores will be used to determine participant satisfaction.
Overt Aggression Scale-Modified (OAS-M)
Time frame: Baseline to 1 month post treatment (approximately 11-18 weeks)
A 17-item measure that assesses frequency of different aggression acts in outpatient settings, including verbal and physical aggression against self, other, and objects. The OAS-M is scored by summing the instances of aggression since the last assessment. The OAS-M had been administered as an interview as well as self-report and will be administered as a self-report in this study, consistent with past aggression research with veterans (Miles, Kent et al., 2020). The score is calculated using a sum total of all instances of aggression. Higher scores indicate a greater frequency of aggressive behaviors.
Inventory of Interpersonal Problems-Short Version (IIP-32)
Time frame: Baseline to 1 month post treatment (approximately 11-18 weeks)
A 32-item self-report assessment designed to measure interpersonal functioning. Items are scored on a five-point scale from 0 (not at all) to 4 (extremely) in response to the stem: "How much have you been distressed by this problem?" There are 8 factors and a total score. The 8 factors are: hard to be assertive, hard to be sociable, hard to be supportive, too dependent, too caring, too aggressive, hard to be involved and too open. The possible total score ranges from a T-score are 0-100. T-scores that are higher than 60 are above average and T-scores 70 or higher suggest significant interpersonal difficulty.
State Trait Anger Expression Inventory-2 (STAXI-2)
Time frame: Baseline to 1 month post treatment (approximately 11-18 weeks)
A 57-item inventory which measures the frequency and intensity of anger as an emotional state. There are 6 scales, 5 subscales, and an Anger Expression Index (total anger expression). The State Anger scale (15 items) measures anger intensity as a momentary emotional state, while the Trait Anger scale (10 items) measures the disposition to experience angry feelings as a personality-like trait over lengthy time periods (i.e., the individual's disposition to become angry or angry temperament). The Anger Expression scale (16 items) and the Anger Control scale (16 items) measure four anger-related trait dimensions. Ratings of items are on a 4-point response scales that measure state anger (intensity) as well as trait anger (frequency). The possible total range is a T-score from 0 to 100. Individuals with anger scores higher than the 75-percentile experience and/ or express angry feelings to a degree that may interfere with optimal functioning.
6 secondary outcomes
Rate of protocol completion
Time frame: Treatment end (Approximately 7-14 weeks)
Number of modules completed
Time frame: Baseline to end of treatment (approximately 7-14 weeks)
Brief Inventory of Psychosocial Functioning (B-IPF)
Time frame: Baseline to 1 month post treatment (approximately 11-18 weeks)
Dimensions of Anger Reactions (DAR-5)
Time frame: Baseline to 1 month post treatment (approximately 11-18 weeks)
Revised Conflict Tactics Scale Short Form (CTS-2)
Time frame: Baseline to 1 month post treatment (approximately 11-18 weeks)
Trauma-Related Anger Scale (TRAS)
Time frame: Baseline to 1 month post treatment (approximately 11-18 weeks)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Apr 2026.
- Individual participant dataSharing planned: Yes. At the conclusion of the study all data will be stripped of identifiers. De-identified (anonymized) data will be maintained indefinitely in the STRONG STAR Repository. Identifiable data from participants who signed the consent to have their data placed in the STRONG STAR Repository will be maintained under the UTHSCSA IRB-approved Repository protocol indefinitely.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Vanessa Jacoby, PhD principal investigator
The University of Texas Health Science Center at San Antonio
Alan Peterson, PhD principal investigator
The University of Texas Health Science Center at San Antonio
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Countering Chronic Anger and Aggression Related to Trauma and Transgressions (CART) in people with Anger Problems and Aggression, run by The University of Texas Health Science Center at San Antonio at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 1 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Vanessa Jacoby, PhD ((254) 289-3468, jacobyv@uthscsa.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Successful recruitment (time frame: Study start to last subject enrolled, approximately 1 year). The study lists 5 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Apr 2026.