Alcohol ConsumptionASPIRENCT06617702
Accountability Support Through Peer-Inspired Relationships and Engagement (ASPIRE) Trial
A study testing A text message alcohol intervention focused on cognitive, behavioral, and peer influences and A text message alcohol intervention focused on cognitive and behavioral influences in people with Alcohol Consumption, run by Stanford University at 1 site in United States.
Trial summary
This project aims to test the efficacy of a text message intervention, ASPIRE, designed to address cognitive and behavioral elements and modify exposure to peers that influence drinking behaviors. Read more about this study
- Who is it for?
- Ages 18 to 25 years
- Conditions the study is for
- Alcohol Consumption
- What is being tested?
- A text message alcohol intervention focused on cognitive, behavioral, and peer influences and A text message alcohol intervention focused on cognitive and behavioral influences
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 300 participants
- Where
- 1 siteUnited States
- Study dates
- 10 Apr 2025to May 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 25 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Age 18-25 years (verified using date of birth)
- Lives in the U.S. (based on zip code)
- English reader (verified based on completing screen)
- 2+ days with ≧4 standard alcohol drinks for women or ≧5 standard alcohol drinks for men in past month
- Owns a mobile phone with SMS (verified by texting enrollment procedure)
Who cannot join
- Currently enrolled or past enrollment in a 4-year college
- Active military
- Pregnant or pregnancy plans in the next 12-months
- Prisoner status
- Current or planned treatment for alcohol or substance use disorder in next 12-months
Trial locations and contacts
1 site in 1 country.
About this study
Official title: ASPIRE to Change: Leveraging Text Messaging Peer Support Coaching to Mitigate Hazardous Alcohol Consumption in Non-Collegiate Young Adults
This project aims to test the efficacy of a text message intervention, ASPIRE, designed to address cognitive and behavioral elements and modify exposure to peers that influence drinking behaviors. Young adults who are contemplating reducing their drinking will be recruited from a national sample and randomized to ASPIRE versus a text message intervention focused solely on cognitive and behavioral elements. We will measure effectiveness at 3, 6, and 12 months, study mechanisms driving behavior change, and identify which subgroups stand to benefit most.
- Conditions
- Alcohol Consumption
- Being tested
- A text message alcohol intervention focused on cognitive, behavioral, and peer influences, A text message alcohol intervention focused on cognitive and behavioral influences
- Keywords
- alcohol, text message, young adults, peers
- Medical subject headings
- Alcohol Drinking
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
A text message alcohol intervention focused on cognitive, behavioral, and peer influencesBehavioural
Each Thursday and Sunday ASPIRE will conduct brief text message communication aimed at modifying cognitive (e.g.desire to get drunk), behavioral (e.g.alcohol consumption), and peer influences (e.g.peer pressure and support).
A text message alcohol intervention focused on cognitive and behavioral influencesBehavioural
Each Thursday and Sunday ASPIRE will conduct brief text message communication aimed at modifying cognitive (e.g. desire to get drunk) and behavioral (e.g. alcohol consumption) influences.
| Study group | Role | What they receive |
|---|---|---|
| A text message alcohol intervention focused on cognitive, behavioral, and peer influences | Experimental | Not described Receives: Behavioral: A text message alcohol intervention focused on cognitive, behavioral, and peer influences |
| A text message alcohol intervention focused on cognitive and behavioral influences | Active comparator | Not described Receives: Behavioral: A text message alcohol intervention focused on cognitive and behavioral influences |
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of Binge Drinking Days (BDD)
We define BDD as a day when a woman reports 4 or more standard drinks or a man reports 5 or more standard drinks, as this equates to the alcohol consumption that raises blood alcohol concentration to 0.08 g/dl or above.
Measured: 3, 6, and 12 months
Secondary outcomes (1)
Negative Alcohol Consequences (NAC) Scale Score
We calculate the number of NAC using the Brief Young Adult Alcohol Consequences Questionnaire (B-YAACQ). The B-YAACQ is a 24-item measure of alcohol-related problems that utilizes a dichotomous (present or absent) scoring format. Higher scores indicate both wider variety and more severe pattern of alcohol-related problems.
Measured: 3, 6 and 12 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Sep 2024
- Study start10 Apr 2025
- Primary completionDec 2026 (estimated)
- Study completionMay 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Alcohol ConsumptionStudies of the same condition, open and under way.
- More trials run by Stanford UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Investigator, Outcomes assessor
- Enrolment
- 300 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Stanford University
- Sponsor type
- University, hospital or other
- Collaborators
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Responsible party
- Principal investigator, Brian Suffoletto, Stanford University
- Investigators
- Brian Suffoletto, MD, Principal investigator, Stanford University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06617702
- Sponsor's protocol ID
- 76956
- Other IDs
- 1R01AA030986-01A1
- Acronym
- ASPIRE
- Status last verified
- Oct 2026
- First submitted
- 26 Sep 2024
- Last updated
- 29 Oct 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: All test message and web-based data from baseline through 12-month followups will be uploaded to the data repository (the National Institute on Alcohol Abuse and Alcoholism Data Archive (NIAAADA).
Publications
Kahler CW, Hustad J, Barnett NP, Strong DR, Borsari B. Validation of the 30-day version of the Brief Young Adult Alcohol Consequences Questionnaire for use in longitudinal studies. J Stud Alcohol Drugs. 2008 Jul;69(4):611-5. doi: 10.15288/jsad.2008.69.611.
PubMed 18612578Sobell LC, Brown J, Leo GI, Sobell MB. The reliability of the Alcohol Timeline Followback when administered by telephone and by computer. Drug Alcohol Depend. 1996 Sep;42(1):49-54. doi: 10.1016/0376-8716(96)01263-x.
PubMed 8889403Rueger SY, Trela CJ, Palmeri M, King AC. Self-administered web-based timeline followback procedure for drinking and smoking behaviors in young adults. J Stud Alcohol Drugs. 2012 Sep;73(5):829-33. doi: 10.15288/jsad.2012.73.829.
PubMed 22846247
Study at a glance
From the registry record, last updated by the sponsor on 29 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- ASPIRE to Change: Leveraging Text Messaging Peer Support Coaching to Mitigate Hazardous Alcohol Consumption in Non-Collegiate Young Adults
- ClinicalTrials.gov ID
- NCT06617702
- Acronym / sponsor ID
- ASPIRE / 76956
- Conditions
- Alcohol Consumption
- Keywords
- alcohol, text message, young adults, peers
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 300 participants (estimated)
- Lead sponsor
- Stanford UniversityUniversity, hospital or other
- Collaborators
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
- Study start
- 10 Apr 2025 (actual)
- Primary completion
- Dec 2026 (estimated)
- Study completion
- May 2027 (estimated)
- First posted
- 27 Sep 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This project aims to test the efficacy of a text message intervention, ASPIRE, designed to address cognitive and behavioral elements and modify exposure to peers that influence drinking behaviors. Young adults who are contemplating reducing their drinking will be recruited from a national sample and randomized to ASPIRE versus a text message intervention focused solely on cognitive and behavioral elements. We will measure effectiveness at 3, 6, and 12 months, study mechanisms driving behavior change, and identify which subgroups stand to benefit most.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (investigator, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| A text message alcohol intervention focused on cognitive, behavioral, and peer influences | Experimental | Behavioral: A text message alcohol intervention focused on cognitive, behavioral, and peer influences |
| A text message alcohol intervention focused on cognitive and behavioral influences | Active comparator | Behavioral: A text message alcohol intervention focused on cognitive and behavioral influences |
Who may qualify
- Ages
- 18 to 25 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Age 18-25 years (verified using date of birth)
- Lives in the U.S. (based on zip code)
- English reader (verified based on completing screen)
- 2+ days with ≧4 standard alcohol drinks for women or ≧5 standard alcohol drinks for men in past month
- Owns a mobile phone with SMS (verified by texting enrollment procedure)
Key exclusion criteria (5 listed)
- Currently enrolled or past enrollment in a 4-year college
- Active military
- Pregnant or pregnancy plans in the next 12-months
- Prisoner status
- Current or planned treatment for alcohol or substance use disorder in next 12-months
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| A text message alcohol intervention focused on cognitive, behavioral, and peer influencesEach Thursday and Sunday ASPIRE will conduct brief text message communication aimed at modifying cognitive (e.g.desire to get drunk), behavioral (e.g.alcohol consumption), and peer influences (e.g.peer pressure and support). | Behavioural | A text message alcohol intervention focused on cognitive, behavioral, and peer influences |
| A text message alcohol intervention focused on cognitive and behavioral influencesEach Thursday and Sunday ASPIRE will conduct brief text message communication aimed at modifying cognitive (e.g. desire to get drunk) and behavioral (e.g. alcohol consumption) influences. | Behavioural | A text message alcohol intervention focused on cognitive and behavioral influences |
Primary outcome
Number of Binge Drinking Days (BDD)
Time frame: 3, 6, and 12 months
We define BDD as a day when a woman reports 4 or more standard drinks or a man reports 5 or more standard drinks, as this equates to the alcohol consumption that raises blood alcohol concentration to 0.08 g/dl or above.
1 secondary outcome
Negative Alcohol Consequences (NAC) Scale Score
Time frame: 3, 6 and 12 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 29 Oct 2026.
- Background: PubMed 18612578Kahler CW, Hustad J, Barnett NP, Strong DR, Borsari B. Validation of the 30-day version of the Brief Young Adult Alcohol Consequences Questionnaire for use in longitudinal studies. J Stud Alcohol Drugs. 2008 Jul;69(4):611-5. doi: 10.15288/jsad.2008.69.611.
- Background: PubMed 8889403Sobell LC, Brown J, Leo GI, Sobell MB. The reliability of the Alcohol Timeline Followback when administered by telephone and by computer. Drug Alcohol Depend. 1996 Sep;42(1):49-54. doi: 10.1016/0376-8716(96)01263-x.
- Background: PubMed 22846247Rueger SY, Trela CJ, Palmeri M, King AC. Self-administered web-based timeline followback procedure for drinking and smoking behaviors in young adults. J Stud Alcohol Drugs. 2012 Sep;73(5):829-33. doi: 10.15288/jsad.2012.73.829.
- Individual participant dataSharing planned: Yes. All test message and web-based data from baseline through 12-month followups will be uploaded to the data repository (the National Institute on Alcohol Abuse and Alcoholism Data Archive (NIAAADA).
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Brian Suffoletto, MD principal investigator
Stanford University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing A text message alcohol intervention focused on cognitive, behavioral, and peer influences and A text message alcohol intervention focused on cognitive and behavioral influences in people with Alcohol Consumption, run by Stanford University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 29 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of Binge Drinking Days (BDD) (time frame: 3, 6, and 12 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06617702, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 29 Oct 2026.