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Sprint PerformancePAP-SPNCT06619899

Post-activation Potentiation and Sprinting Performance

A study testing PAP exercise with 0% body mass, PAP exercise with 20% body mass and No PAP exercise in people with Sprint Performance, run by University of Thessaly at 1 site in Greece.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

Scientific data regarding the post-activation potentiation (PAP) phenomenon on sprinting performance is scarce, especially regarding the effect of performing pre-conditioning power exercises on subsequent sprinting performance. Read more about this study

Who is it for?
Ages 18 to 30 yearsHealthy volunteers can take part
Conditions the study is for
Sprint Performance
What is being tested?
PAP exercise with 0% body mass, PAP exercise with 20% body mass and No PAP exercise
Could I receive a placebo?
Yes, some participants may receive a placebo
How many people
15 participants
Where
1 siteGreece
Study dates
1 Sep 2024to 15 Nov 2024
Phase
Interventional
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 30 years
  • All sexes
  • Healthy volunteers accepted
  • Adult

Who may be able to join

  • Age: 18 - 30 years old
  • Srinters or athletes that comprise sprint training in their training programs
  • Absense of musculoskeletal injuries (≥ 6 months)
  • Abstence from use of ergogenic supplements or other drugs (≥ 1 month)
  • Abstence from participation at exercise with eccentric component (≥ 3 days)
  • Abstence from alcohol and energy drings consumption before each experimental trial

Who cannot join

  • Age: Older than 18 - 30 years
  • Musculoskeletal injuries (≤ 6 months)
  • Use of ergogenic supplements or other drugs (≤ 1 month)
  • Participation at exercise with eccentric component (≤ 3 days)
  • Alcohol and energy drings consumption before the experimental trials

Trial locations and contacts

1 site in 1 country.

Greece1 site
  • Department of Physical Education and Sport Science, University of Thessaly

    Trikala, Thessaly, 42100

Other trials in Greece

About this study

Official title: Investigation of Post-activation Potentiation Phenomenon οn Sprinting Performance Following Power Pre-conditioning Exercise

Scientific data regarding the post-activation potentiation (PAP) phenomenon on sprinting performance is scarce, especially regarding the effect of performing pre-conditioning power exercises on subsequent sprinting performance. Additionally, there is no data regarding the rate of fatigue onset when power pre-conditioning exercise before sprints are performed repeatedly at the same training session. This research will provide important information to coaches and athletes for the design of an optimum training program for the maximization of the athletes' performance and the avoidance of injuries.

Read the detailed description

Sprinting ability is an imperative quality for many sports, especially for sprint and power athletes. Regular sprint training improves acceleration, maximal speed and power. Thus, sprint training consists one of the basic elements of the athletes' training program.

One method used by coaches to improve performance is the implementation of a pre-conditioning exercise aiming to post-activation potentiation (PAP). Post-activation potentiation phenomenon refers to the increase in performance following a maximal or near maximal muscle contraction (e.g. a pre-conditioning exercise). However, the effectiveness of such an approach is under debate, such that improvement, but also no improvement, or even deterioration of the performance following pre-conditioning exercises has been reported. The improvement of performance following a pre-conditioning exercise seems to depend on the relationship between muscle twitch potentiation and fatigue following the pre-conditioning exercise. When muscle twitch potentiation is greater than muscle fatigue, then the PAP mechanism will be activated and performance will be improved. Contrary, under similar muscle twitch potentiation and fatigue, performance will not change, and when muscle twitch potentiation is lower than fatigue, muscle performance will decrease. PAP phenomenon has been studied mainly regarding its effectiveness to improve jumping performance, while its effectiveness on improving sprinting performance has not been adequately studied. However, information regarding the effectiveness of the implementation of pre-conditioning exercises aiming to improve sprinting performance, is important for the design of an optimum training program for the maximization of the athletes' performance and the avoidance of injuries.

The aim of this study is to investigate a) the effectiveness of the implementation of a pre-conditioning exercise to activate the PAP mechanism and improve performance of a following sprint, and b) to investigate whether PAP is maintained in repeated efforts during the same training session.

The study will be implemented in a randomized, cross over, repeated measures design, at three cycles.

According to a preliminary power analysis (a probability error of 0.05, and a statistical power of 80%), a sample size of 8 - 10 participants was considered appropriate in order to detect statistically meaningful differences between groups. Considering a possible drop-out, 15 participants will be recruited. Procedures will be in accordance with the 1964 Declaration of Helsinki, as revised in 2013.

Before the experimental procedures, all participants will sign an informed consent form after they will be informed about all the benefits and risks of the study, and they will also fill in a medical history questionnaire. Participants will then perform baseline measurements at the Laboratory of Biochemistry, Physiology and Nutrition of Exercise (SmArT Lab), Department of Physical Education and Sport Science, University of Thessaly: anthropometric characteristics (body height, body mass, body mass index) via a stadiometer-scale (Stadiometer 208; Seca, Birmingham, UK), body composition (percent of body fat, lean body mass, fat mass, bone density) via dual emission X-ray absorptiometry (DXA, GE-Healthcare, Lunar DPX NT, Belgium), isokinetic strength (isometric, concentric and eccentric torque of the knee extensors and knee flexors of both limbs) on an isokinetic dynamometer (Cybex, HUMAC NORM 360, Ronkonkoma, NY). The individual optimum rest period between the pre-conditioning exercise and the subsequent 30-m sprint will be estimated, in order each participant to perfrom each 30-m sprint under an optimal condition. The rest periods of 3, 6, and 9 minutes will be tested for each participant and the rest period that leads to the best sprinting performance will be applied during the experimental training protocols.

Participants will then perform 6 x 30-m sprints under three different conditions in a random order: a) control trial (sprint training without pre-conditioning exercise), b) sprint training with pre-conditioning exercise (2 x 4 squat jumps with 0% of 1RM at squat), and c) sprint training with pre-conditioning exercise (2 x 4 squat jumps with 20% of 1RM at squat). The randomization of the trials will be made via a random integer set generator (Random.org) available online.

Prior to, and following each 30-m sprint, assessment of muscle soreness in the knee flexors and knee extensors, countermovement jump height, and blood lactate concentration, will be performed during each training session. The exact above procedures will be repeated by the participants during the remaining two experimental trials. Between trials, a wash-out period of 7 days will be applied.

Being tested
PAP exercise with 0% body mass, PAP exercise with 20% body mass, No PAP exercise
Keywords
post-activation potentiation, sprinting performance, power pre-conditioning exercise, speed

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • PAP exercise with 0% body massOther

    Also called post-activation potentiation training, sprint training

    The participants will perform 6 x 30m sprints. Before each sprint they will perform 2 x 4 countermovement jumps with 0% body mass.

  • PAP exercise with 20% body massOther

    Also called post-activation potentiation training, sprint training

    Description: The participants will perform 6 x 30m sprints. Before each sprint they will perform 2 x 4 countermovement jumps with 0% body mass

  • No PAP exerciseOther

    Also called post-activation potentiation training, sprint training

    No PAP exercise will be performed. The participants will perform only 6 x 30m sprints.

Study groups in NCT06619899
Study groupRoleWhat they receive
PAP exercise with 0% body massExperimentalThe participants will perform 6 x 30m sprints. A pre-conditioning exercise (2 sets x 4 countermovement jumps with 0% body mass).
Receives: Other: PAP exercise with 0% body mass
PAP exercise with 20% body massExperimentalThe participants will perform 6 x 30m sprints. A pre-conditioning exercise (2 sets x 4 countermovement jumps with 20% body mass).
Receives: Other: PAP exercise with 20% body mass
No PAP exercisePlacebo comparatorThe participants will perform only 6 x 30m sprints. No pre-conditioning exercise will be performed.
Receives: Other: No PAP exercise

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Changes in 30 m sprint performance

    30-m sprint performance will be assessed via photocells.

    Measured: Pre, 9, 18, 27, 36, and 45 minutes during the sprint training session.

Secondary outcomes (3)
  1. Changes in muscle soreness in the knee flexors and extensors of both limbs

    Muscle soreness will be assessed immediately post each 30-m sprint. Muscle soreness will be assessed via palpation of the muscle belly and the distal regions following 3 squats, and the subjective pain will be recorded on a 10-point scale (1 = no pain, 10 = extreme pain)

    Measured: Pre, 9, 18, 27, 36, and 45 minutes during the sprint training session.

  2. Changes in countermovement jump performance

    Countermovement jump performance will be assessed 3 minutes post each 30-m sprint via an optical measurement system

    Measured: Pre, 12, 21, 30, 39, and 58 minutes during the sprint training session.

  3. Changes in lactate

    Lactate will be measured 4 minutes following each 30-m sprint via a lactate portable analyser.

    Measured: Pre, 13, 22, 31, 40, and 49 minutes during the sprint training session.

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted1 Oct 2024
  2. Study start1 Sep 2024
  3. Primary completion15 Nov 2024
  4. Study completion15 Nov 2024

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Screening
Allocation
Randomised
Intervention model
Crossover
Masking
None (open label)
Enrolment
15 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT06619899
Sponsor's protocol ID
PAP-Sprinting
Acronym
PAP-SP
Status last verified
Dec 2024
First submitted
17 Sep 2024
Last updated
4 Dec 2024
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No

Publications

  • Seitz LB, Haff GG. Factors Modulating Post-Activation Potentiation of Jump, Sprint, Throw, and Upper-Body Ballistic Performances: A Systematic Review with Meta-Analysis. Sports Med. 2016 Feb;46(2):231-40. doi: 10.1007/s40279-015-0415-7.

    PubMed 26508319
  • Rassier DE, Macintosh BR. Coexistence of potentiation and fatigue in skeletal muscle. Braz J Med Biol Res. 2000 May;33(5):499-508. doi: 10.1590/s0100-879x2000000500003.

    PubMed 10775880
  • Hodgson M, Docherty D, Robbins D. Post-activation potentiation: underlying physiology and implications for motor performance. Sports Med. 2005;35(7):585-95. doi: 10.2165/00007256-200535070-00004.

    PubMed 16026172
  • Bridgett LA, Linthorne NP. Changes in long jump take-off technique with increasing run-up speed. J Sports Sci. 2006 Aug;24(8):889-97. doi: 10.1080/02640410500298040.

    PubMed 16815784

Questions about this trial

What is this clinical trial studying?

A study testing PAP exercise with 0% body mass, PAP exercise with 20% body mass and No PAP exercise in people with Sprint Performance, run by University of Thessaly at 1 site in Greece.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 4 Dec 2024. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Greece. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Changes in 30 m sprint performance (time frame: Pre, 9, 18, 27, 36, and 45 minutes during the sprint training session.). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT06619899, which also lists 4 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Dec 2024.

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