HypertensionNCT06628635
Examining Different Modes of Exercise for Acute Reduction in Blood Pressure
A study testing Exercise and Resting in people with Hypertension, run by University of Saskatchewan at 1 site in Canada.
Trial summary
The purpose of the study is to compared different modes of exercise for eliciting post-exercise hypotension. The study will randomize 10 healthy participants to 30 minutes of either aerobic exercise, isometric exercise, stretching, or rest (control). Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Hypertension
- What is being tested?
- Exercise and Resting
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 10 participants
- Where
- 1 siteCanada
- Study dates
- 4 Jan 2024to 15 Apr 2024
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
- Able to safely perform exercise according to the Get Active Questionnaire
Who cannot join
- Taking blood pressure medications
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Examining the Effects of Aerobic Exercise, Isometrics, and Stretching on Acute (Post-exercise) Blood Pressure Reduction
The purpose of the study is to compared different modes of exercise for eliciting post-exercise hypotension. The study will randomize 10 healthy participants to 30 minutes of either aerobic exercise, isometric exercise, stretching, or rest (control). Blood pressure and heart rate will be assessed before and for one hour post-exercise.
Read the detailed description
The purpose is to compare different modes of exercise (aerobic vs. isometric vs. static stretching) for reducing blood pressure post-exercise. : Using a randomized crossover design, 5 male and 5 female (n=10) normotensive university students will participate in four different exercise sessions for 30 minutes: aerobic (cycle ergometer at 70% of VO2max), isometric (alternating wall-sit for 70% of max, and handgrip dynamometer at 30% of max for 2 minutes), stretching (targeting the larger muscle groups of the body), and control (rest). Participants' blood pressure and heart rate will be measured before each exercise session and monitored for 60 minutes afterwards to analyze the post-exercise hypotensive response.
- Conditions
- Hypertension
- Being tested
- Exercise, Resting
- Keywords
- blood pressure, exercise
- Medical subject headings
- Hypertension, Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ExerciseBehavioural
Exercise involving aerobics, isometrics, and stretching
RestingBehavioural
Resting
| Study group | Role | What they receive |
|---|---|---|
| Aerobic exercise | Experimental | 30 minutes of moderate-intensity aerobic exercise on a cycle ergometer Receives: Behavioral: Exercise |
| Isometric exercise | Experimental | 30 minutes of isometric exercise (alternating hand-grip with wall-sitting) Receives: Behavioral: Exercise |
| Static stretching | Experimental | 30 minutes of static stretching of major muscle groups Receives: Behavioral: Exercise |
| Resting control | Active comparator | 30 minutes of seated rest Receives: Behavioral: Resting |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in systolic blood pressure (mmHg)
Measured: Baseline to 60 minutes after exercise
Change in diastolic blood pressure (mmHg)
Measured: Baseline to 60 minutes after exercise
Secondary outcomes (2)
Change in heart rate (beats per minute)
Measured: Baseline to 60 minutes after exercise
Change in rate-pressure product (beats per mintues x systolic blood pressure mmHg)
Measured: Change from baseline to 60 minutes after exercise
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted8 Oct 2024
- Study start4 Jan 2024
- Primary completion10 Apr 2024
- Study completion15 Apr 2024
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for HypertensionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 10 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of Saskatchewan
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Phil Chilibeck, University of Saskatchewan
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06628635
- Sponsor's protocol ID
- 2023_24_09
- Status last verified
- Oct 2024
- First submitted
- 3 Oct 2024
- Last updated
- 8 Oct 2024
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Keller C, Chilibeck P. Stretching, isometrics, and aerobic exercise for decreasing blood pressure post-exercise: a randomized crossover study. Appl Physiol Nutr Metab. 2025 Jan 1;50:1-6. doi: 10.1139/apnm-2024-0439.
PubMed 39869856
Study at a glance
From the registry record, last updated by the sponsor on 8 Oct 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Examining the Effects of Aerobic Exercise, Isometrics, and Stretching on Acute (Post-exercise) Blood Pressure Reduction
- ClinicalTrials.gov ID
- NCT06628635
- Acronym / sponsor ID
- 2023_24_09
- Conditions
- Hypertension
- Keywords
- blood pressure, exercise
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 10 participants (actual)
- Lead sponsor
- University of SaskatchewanUniversity, hospital or other
- Study start
- 4 Jan 2024 (actual)
- Primary completion
- 10 Apr 2024 (actual)
- Study completion
- 15 Apr 2024 (actual)
- First posted
- 8 Oct 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of the study is to compared different modes of exercise for eliciting post-exercise hypotension. The study will randomize 10 healthy participants to 30 minutes of either aerobic exercise, isometric exercise, stretching, or rest (control). Blood pressure and heart rate will be assessed before and for one hour post-exercise.
Detailed description
The purpose is to compare different modes of exercise (aerobic vs. isometric vs. static stretching) for reducing blood pressure post-exercise. : Using a randomized crossover design, 5 male and 5 female (n=10) normotensive university students will participate in four different exercise sessions for 30 minutes: aerobic (cycle ergometer at 70% of VO2max), isometric (alternating wall-sit for 70% of max, and handgrip dynamometer at 30% of max for 2 minutes), stretching (targeting the larger muscle groups of the body), and control (rest). Participants' blood pressure and heart rate will be measured before each exercise session and monitored for 60 minutes afterwards to analyze the post-exercise hypotensive response.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 4
| Arm | Type | Receives |
|---|---|---|
| Aerobic exercise | Experimental | Behavioral: Exercise30 minutes of moderate-intensity aerobic exercise on a cycle ergometer |
| Isometric exercise | Experimental | Behavioral: Exercise30 minutes of isometric exercise (alternating hand-grip with wall-sitting) |
| Static stretching | Experimental | Behavioral: Exercise30 minutes of static stretching of major muscle groups |
| Resting control | Active comparator | Behavioral: Resting30 minutes of seated rest |
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (1 listed)
- Able to safely perform exercise according to the Get Active Questionnaire
Key exclusion criteria (1 listed)
- Taking blood pressure medications
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ExerciseExercise involving aerobics, isometrics, and stretching | Behavioural | Aerobic exercise, Isometric exercise, Static stretching |
| RestingResting | Behavioural | Resting control |
Primary outcome
Change in systolic blood pressure (mmHg)
Time frame: Baseline to 60 minutes after exercise
Change in diastolic blood pressure (mmHg)
Time frame: Baseline to 60 minutes after exercise
2 secondary outcomes
Change in heart rate (beats per minute)
Time frame: Baseline to 60 minutes after exercise
Change in rate-pressure product (beats per mintues x systolic blood pressure mmHg)
Time frame: Change from baseline to 60 minutes after exercise
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Oct 2024.
- Derived from this study: PubMed 39869856Keller C, Chilibeck P. Stretching, isometrics, and aerobic exercise for decreasing blood pressure post-exercise: a randomized crossover study. Appl Physiol Nutr Metab. 2025 Jan 1;50:1-6. doi: 10.1139/apnm-2024-0439.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Exercise and Resting in people with Hypertension, run by University of Saskatchewan at 1 site in Canada.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 8 Oct 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in systolic blood pressure (mmHg) (time frame: Baseline to 60 minutes after exercise). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06628635, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Oct 2024.