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Cairo UniversityNCT06653543

Effect of Mulligan on Cervical Radiculopathy

A study testing Mulligan mobilization with arm movement and conventional therapy of cevical radiculopathy in people with Cairo University, run by Cairo University at 1 site in Egypt.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
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Trial summary

The goal of this clinical trial is to investigate the effect of Mulligan mobilization with arm movement on nerve conduction velocity in patients with unilateral cervical radiculopathy. The main questions it aims to answer are : 1. Read more about this study

Who is it for?
Ages 20 to 60 years
Conditions the study is for
Cairo University
What is being tested?
Mulligan mobilization with arm movement and conventional therapy of cevical radiculopathy
Could I receive a placebo?
Yes, some participants may receive a placebo
How many people
40 participants
Where
1 siteEgypt
Study dates
1 Jan 2025to 10 Aug 2025
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 20 to 60 years
  • All sexes
  • No healthy volunteers
  • Adult

Who may be able to join

  • • diagnosed with cervical radiculopathy .
  • Age group between 20-60 years
  • Unilateral radiating pain through the course of median nerve .
  • Subject having positive upper limb tension test (ULTT 1)
  • either gender male and female
  • Subjects who can understand the instructions and are willing to participate in the study.

Who cannot join

  • • History of trauma, dislocation and subluxation of upper extremity
  • Rheumatoid Arthritis
  • Malignancy
  • Spinal canal stenosis .
  • Cervical instability/Spondylolisthesis
  • VBI (Vertebral-Basillar Insufficiency)
Show all 12Show fewer
  • Referred pain in patients with cardiac ischemia
  • Cervical or thoracic spine surgeries .
  • systemic causes like diabetic neuropathy .
  • recent fracture or surgery in and around the shoulder .
  • carpal tunnel syndrome .
  • thoracic outlet syndrome .

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Egypt1 site, 1 recruiting
  • Kafr El-Sheikh university

    Kafr El-Sheikh Governorate, Kafr el-Sheikh Governorate, 33516

    university, 047 3109590, tawfiq.algazar_a010@pt.kfs.edu.eg

    Recruiting

Other trials in Egypt

About this study

Official title: Effect of Mulligan Mobilization With Arm Movement on Nerve Conduction Velocity in Patients With Unilateral Cervical Radiculopathy

The goal of this clinical trial is to investigate the effect of Mulligan mobilization with arm movement on nerve conduction velocity in patients with unilateral cervical radiculopathy. The main questions it aims to answer are :

  1. Is there a statistical significant effect of mobilization with arm movement on NCV velocity in treatment of cervical radiculopathy ?
  2. Is there a statistical significant effect of mobilization with arm movement on pain level in treatment of cervical radiculopathy ?
  3. Is there a statistical significant effect of mobilization with arm movement on cervical ROM in treatment of cervical radiculopathy ?
  4. Is there a statistical significant effect of mobilization with arm movement on neck disability level in treatment of cervical radiculopathy ?

The course of treatment involves 6 sessions over the course of 3 weeks participants will be divided into 2 groups : Control group : recieves only Conventional treatment Experimental group : recieves Conventional treatment and Mulligan mobilization with arm movement .

Read the detailed description

the aim of our study is to examine the effect of Mulligan mobilization with arm movement on cervical radiculopathy using nerve conduction studies , in addition to the original measures of previous studies (pain level, cervical ROM and neck disability scale) .

Delimitations :

Inclusion Criteria

Individuals will be enrolled into the study if they are :

  • diagnosed with cervical radiculopathy .
  • Age group between 20-60 years
  • Unilateral radiating pain through the course of median nerve .
  • Subject having positive upper limb tension test (ULTT 1)
  • either gender male and female
  • Subjects who can understand the instructions and are willing to participate in the study.

Exclusion Criteria .

  • History of trauma, dislocation and subluxation of upper extremity
  • Rheumatoid Arthritis
  • Malignancy
  • Spinal canal stenosis .
  • Cervical instability/Spondylolisthesis
  • VBI (Vertebral-Basillar Insufficiency)
  • Referred pain in patients with cardiac ischemia
  • Cervical or thoracic spine surgeries
  • systemic causes like diabetic neuropathy.
  • recent fracture or surgery in and around the shoulder
  • carpal tunnel syndrome .
  • thoracic outlet syndrome .

Outcome measure would include:

  1. The primary outcome measure will be NCV velocity, for the median nerve (latency, amplitude, Duration , F-wave and nerve conduction velocity of motor nerve action potentials and sensory nerve action potentials (SNAPs)) .
  2. Secondary outcome measures will include:
  • Pain intensity, assessed using the Visual Analog Scale (VAS) .
  • Functional disability, evaluated using the Neck Disability Index (NDI) .
  • Cervical range of motion, measured using a CROM goniometer to assess flexion, extension, lateral flexion, and rotation.
  • The course of treatment involves 6 sessions over the course of 3 weeks .
  • pre-treatment for both groups :
  1. affected nerve conduction velocity will be measured using nerve conduction study .
  2. neck disability level will be measured using neck disability index .
  3. cervical ROM measurement will be taken in all directions using CROM goniometer .
  4. pain will be assessed using Visual analog scale . participants will be divided into 2 groups :

Group A- Control group:

During each session : only Conventional treatment will be provided , includes : hot pack for 10 minutes, active ranges of motion (AROMs) with 3 sets of 10 repetitions and isometrics for each movement repeated 20 times with the hold of 6 to 10 seconds in each repetition.

Group B- Experimental group- Mulligan mobilization group:

  • During each session :
  1. Conventional treatment will be provided .
  2. Mulligan mobilization will be applied in the form of : sustained passive accessory joint mobilization to a specific spinal vertebra level while simultaneously guiding the patient through an active, pain-free movement pattern involving the affected limb :
  • Patient position : Sitting upright on chair
  • Therapist position : Standing behind the patient .
  • Hand placement : Approach the desired level of spinous process from medial aspect of the thumb of one hand, which may be reinforced by the index finger of the other hand.
  • Mobilization Pure transverse glide is performed from affected to unaffected side. While the glide is sustained, patient performs the offending movements (flexion/abduction/horizontal adduction/horizontal abduction)
Being tested
Mulligan mobilization with arm movement, conventional therapy of cevical radiculopathy
Keywords
mobilization, Mulligan, cervical, radiculopathy
Medical subject headings
Radiculopathy

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Mulligan mobilization with arm movementOther

    mulligan mobilization applied on cervical spine with arm movement

  • conventional therapy of cevical radiculopathyOther

    hot pack for 10 minutes, active ranges of motion (AROMs) with 3 sets of 10 repetitions and isometrics for each movement repeated 20 times with the hold of 6 to 10 seconds in each repetition

Study groups in NCT06653543
Study groupRoleWhat they receive
mulligan groupExperimental20 participants recieving conventional therapy in addition to mulligan mobilization with arm movement
Receives: Other: Mulligan mobilization with arm movement; Other: conventional therapy of cevical radiculopathy
control groupSham comparatorcontrol group that revieves only the conventional therapy
Receives: Other: conventional therapy of cevical radiculopathy

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. median nerve conduction study

    using nerve conduction studies to measure the median nerve (latency, amplitude, Duration , F-wave and nerve conduction velocity of motor nerve action potentials and sensory nerve action potentials ) .

    Measured: 2 weeks

Secondary outcomes (3)
  1. cervical range of motion

    using cervical CROM device to measure the cervical ROM in all 3 planes

    Measured: 2 weeks

  2. pain

    using visual analogue scale for the pain intensity .. where no pain or discomfort(0) , while the severest pain (10) .. the more the pain , the more the points on the scale

    Measured: 2 weeks

  3. neck disability level

    using neck disability index questionnaire consists of 10 items, where each item is scored on a scale of 0 to 5, with 0 indicating no disability and 5 indicating complete disability

    • The total score ranges from 0 to 50.
    • Higher scores indicate greater disability and impairment, while lower scores indicate less disability.

    Measured: 2 weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted22 Oct 2024
  2. Study start1 Jan 2025
  3. Primary completion30 Mar 2025
  4. Study completion10 Aug 2025 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
None (open label)
Enrolment
40 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT06653543
Sponsor's protocol ID
P.T.REC/012/005110
Status last verified
Apr 2025
First submitted
1 Sep 2024
Last updated
27 Apr 2025
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No

Questions about this trial

What is this clinical trial studying?

A study testing Mulligan mobilization with arm movement and conventional therapy of cevical radiculopathy in people with Cairo University, run by Cairo University at 1 site in Egypt.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 6 inclusion and 12 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 27 Apr 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Elgazar (201013863820, tawfiq.algazar_a010@pt.kfs.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

median nerve conduction study (time frame: 2 weeks). It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Apr 2025.

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