HealthyNCT06662149
Exploring the Influence of Sensory Cues on Eating Behavior Using Virtual Reality
A study testing Pleasant Smell and Unpleasant Smell in people with Healthy, run by Penn State University at 1 site in United States.
Trial summary
Many factors influence eating choices among humans (mood, taste, convenience, time of day, etc.). Finding simple ways to decrease food intake or improve food choices could improve weight status and overall health of the general population. Read more about this study
- Who is it for?
- Ages 18 to 29 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy
- What is being tested?
- Pleasant Smell and Unpleasant Smell
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 25 participants
- Where
- 1 siteUnited States
- Study dates
- 15 Dec 2024to 1 Aug 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 29 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Between the ages of 18-29
- Fluent in English
- Free of self-reported food allergies/food sensitivities
- No diagnosis of cognitive or physical disabilities/disorders that may affect appetite or eating behaviors (Examples include Major Depressive Disorder, dementia, or eating disorders)
- No diagnosis of disabilities that may affect sensory proprioception related to virtual reality (Examples include vertigo, epilepsy, and ataxia)
- Not color blind
Show all 9Show fewer
- Does not experience anosmia (inability or weak ability to smell)
- Must have hair ≥3 cm in length at the cortisol sample site (roughly midline of the skull left to right and two inches up from the base of the hairline at the neck).
- No hair transplant in the last 6 months
Who cannot join
- Are younger than 18 or older than 29 years of age
- Not fluent in English
- Have self-reported food allergies
- Have a diagnosis of cognitive or physical disabilities that may affect appetite or eating behaviors (Examples include Major Depressive Disorder, dementia, or eating disorders)
- Have a diagnosis of disabilities that may affect sensory proprioception related to virtual reality (Examples include vertigo, epilepsy, and ataxia)
- Suffers from color blindness
Show all 9Show fewer
- Suffers from anosmia (inability or weak ability to smell)
- Hair shorter than 3 cm in length at the cortisol sample site (roughly midline of the skull left to right and two inches up from the base of the hairline at the neck)
- Has had a hair transplant in the last 6 months
Trial locations and contacts
1 site in 1 country.
United States1 site
Health, Ingestive Behavior, and Technology Laboratory of Pennsylvania State University
State College, Pennsylvania, 16802
About this study
Official title: Dining Out in NYC: Using VR to Investigate the Influence of Multisensory Urban Design Factors on Eating Behavior in Emerging Adults
Many factors influence eating choices among humans (mood, taste, convenience, time of day, etc.). Finding simple ways to decrease food intake or improve food choices could improve weight status and overall health of the general population. The purpose of this study is to see if city and/or nature smells affect human eating behavior within a virtual reality-simulated outdoor café. The researchers of this study believe that a better understanding of how smells affect eating behavior could lead to public guidelines that direct the construction and layout of such outdoor eating environments to better support healthy behaviors.
- Conditions
- Healthy
- Being tested
- Pleasant Smell, Unpleasant Smell
- Keywords
- Virtual Reality, Eating behavior
- Medical subject headings
- Feeding Behavior
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Pleasant SmellOther
The participants will be in an environment with an assumed pleasant smell while consuming the meal.
Unpleasant SmellOther
Participants will be in an environment with an assumed unpleasant smell while consuming the meal.
| Study group | Role | What they receive |
|---|---|---|
| Pleasant First | Experimental | Participants will experience the pleasant smell in the participant's first visit and the unpleasant smell in the participant's second visit. Receives: Other: Pleasant Smell; Other: Unpleasant Smell |
| Unpleasant First | Experimental | Participants will experience the unpleasant smell in the participant's first visit and the pleasant smell in the participant's second visit. Receives: Other: Pleasant Smell; Other: Unpleasant Smell |
What is being measured
The primary outcome is the main question the study is designed to answer.
Food Intake Day 1
Total weight of the meal and individual components of the meal are measured in grams before and after participant consumption. The difference is recorded as the amount consumed by the participant. Grams of food will be converted into kilocalories and reported as energy consumed as well.
Measured: Measured once 5-10 minutes after the end of meal consumption
Food Intake Day 2
Total weight of the meal and individual components of the meal are measured in grams before and after participant consumption. The difference is recorded as the amount consumed by the participant. Grams of food will be converted into kilocalories and reported as energy consumed as well.
Measured: Measured 5-10 minutes after the end of meal consumption
Scent Experience Questionnaire (SEQ) Baseline Visit 1
Answered on a tablet; Participants respond to questions 1-3 using a visual analog scale with opposite descriptors on each end. Question 4 is open response that will be coded as a positive memory/scent or negative memory/scent.
- How pleasant or unpleasant is the smell you are experiencing? (low anchor: extremely unpleasant, high anchor: extremely pleasant)
- How intense is the smell you are experiencing? (low anchor: not detectable, high anchor: very strong)
- How familiar is the smell you are experiencing? (low anchor: completely unknown, high anchor: extremely familiar)
- Does the smell you are experiencing remind you of anything? If so, what?
Measured: Measured 5-10 minutes prior to entering VR environment at Visit 1
Scent Experience Questionnaire (SEQ) Baseline Visit 2
Answered on a tablet; Participants respond to questions 1-3 using a visual analog scale with opposite descriptors on each end. Question 4 is open response that will be coded as a positive memory/scent or negative memory/scent.
- How pleasant or unpleasant is the smell you are experiencing? (low anchor: extremely unpleasant, high anchor: extremely pleasant)
- How intense is the smell you are experiencing? (low anchor: not detectable, high anchor: very strong)
- How familiar is the smell you are experiencing? (low anchor: completely unknown, high anchor: extremely familiar)
- Does the smell you are experiencing remind you of anything? If so, what?
Measured: Measured 5-10 minutes prior to entering VR environment at Visit 2
Scent Experience Questionnaire (SEQ) Post-VR Visit 1
Answered on a tablet; Participants respond to questions 1-3 using a visual analog scale with opposite descriptors on each end. Question 4 is open response that will be coded as a positive memory/scent or negative memory/scent.
- How pleasant or unpleasant is the smell you are experiencing? (low anchor: extremely unpleasant, high anchor: extremely pleasant)
- How intense is the smell you are experiencing? (low anchor: not detectable, high anchor: very strong)
- How familiar is the smell you are experiencing? (low anchor: completely unknown, high anchor: extremely familiar)
- Does the smell you are experiencing remind you of anything? If so, what?
Measured: Measured 1-5 minutes after entering VR environment at Visit 1
Scent Experience Questionnaire (SEQ) Post-VR Visit 2
Answered on a tablet; Participants respond to questions 1-3 using a visual analog scale with opposite descriptors on each end. Question 4 is open response that will be coded as a positive memory/scent or negative memory/scent.
- How pleasant or unpleasant is the smell you are experiencing? (low anchor: extremely unpleasant, high anchor: extremely pleasant)
- How intense is the smell you are experiencing? (low anchor: not detectable, high anchor: very strong)
- How familiar is the smell you are experiencing? (low anchor: completely unknown, high anchor: extremely familiar)
- Does the smell you are experiencing remind you of anything? If so, what?
Measured: Measured 1-5 minutes after entering VR environment at Visit 2
Secondary outcomes (18)
Pleasure-Arousal-Dominance (PAD) Survey Baseline Visit 1
Survey answered on a tablet; participant rates the following questions on a 1-9 scale, with 9 being a stronger feeling of the stated emotion.
- How would you rate the level of pleasure you are experiencing currently?
- How would you rate your current level of arousal (a state of excitement linked to an emotion)? 3 How would you rate the extent to which the emotion makes you feel you are in control of the situation?
Measured: Measured 5-10 minutes prior to entering VR environment at Visit 1
Pleasure-Arousal-Dominance (PAD) Survey Baseline Visit 2
Survey answered on a tablet; participant rates the following questions on a 1-9 scale, with 9 being a stronger feeling of the stated emotion.
- How would you rate the level of pleasure you are experiencing currently?
- How would you rate your current level of arousal (a state of excitement linked to an emotion)? 3 How would you rate the extent to which the emotion makes you feel you are in control of the situation?
Measured: Measured 5-10 minutes prior to entering VR environment at Visit 2
Pleasure-Arousal-Dominance (PAD) Survey Post VR Visit 1
Survey answered on a tablet; Participant is prompted with the following input: Imagine you are in the space you saw when wearing the headset. You are there after a long day's work. Now, how does the architectural space in the image make you feel?
Scale of 1-9. A higher score indicates a stronger feeling in that dimension.
- How would you rate the level of pleasure you experienced in this space?
- How would you rate the level of arousal (a state of excitement linked to an emotion) you experienced in this space? 3 How would you rate the extent to which the emotion makes you feel you are in control of the situation?
Measured: Measured 1-5 minutes after entering VR environment at Visit 1
Pleasure-Arousal-Dominance (PAD) Survey Post VR Visit 2
Survey answered on a tablet; Participant is prompted with the following input: Imagine you are in the space you saw when wearing the headset. You are there after a long day's work. Now, how does the architectural space in the image make you feel?
Scale of 1-9. A higher score indicates a stronger feeling in that dimension.
- How would you rate the level of pleasure you experienced in this space?
- How would you rate the level of arousal (a state of excitement linked to an emotion) you experienced in this space? 3 How would you rate the extent to which the emotion makes you feel you are in control of the situation?
Measured: Measured 1-5 minutes after entering VR environment at Visit 2
Positive Affect Negative Affect Survey (PANAS) Baseline Visit 1
Survey is taken on a tablet; Participant responds according to how much they are feeling that emotion at that moment with a 1-5 scale (1 is not at all and 5 is extremely).
- Interested
- Distressed
- Excited
- Upset
- Strong
- Guilty
- Scared
- Hostile
- Enthusiastic
- Proud
- Irritable
- Alert
- Ashamed
- Inspired
- Nervous
- Determined
- Attentive
- Jittery
- Active
- Afraid
Measured: Measured 5-10 minutes prior to entering VR environment at Visit 1
Positive Affect Negative Affect Survey (PANAS) Baseline Visit 2
Survey is taken on a tablet; Participant responds according to how much they are feeling that emotion at that moment with a 1-5 scale (1 is not at all and 5 is extremely).
- Interested
- Distressed
- Excited
- Upset
- Strong
- Guilty
- Scared
- Hostile
- Enthusiastic
- Proud
- Irritable
- Alert
- Ashamed
- Inspired
- Nervous
- Determined
- Attentive
- Jittery
- Active
- Afraid
Measured: Measured 5-10 minutes prior to entering VR environment at Visit 2
Positive Affect Negative Affect Survey (PANAS) Post-VR Visit 1
Survey is taken on a tablet; Participant responds according to how much they are feeling that emotion in response to the VR space with a 1-5 scale (1 is not at all and 5 is extremely).
- Interested
- Distressed
- Excited
- Upset
- Strong
- Guilty
- Scared
- Hostile
- Enthusiastic
- Proud
- Irritable
- Alert
- Ashamed
- Inspired
- Nervous
- Determined
- Attentive
- Jittery
- Active
- Afraid
Measured: Measured 1-5 minutes after entering VR environment at Visit 1
Positive Affect Negative Affect Survey (PANAS) Post-VR Visit 2
Survey is taken on a tablet; Participant responds according to how much they are feeling that emotion in response to the VR space with a 1-5 scale (1 is not at all and 5 is extremely).
- Interested
- Distressed
- Excited
- Upset
- Strong
- Guilty
- Scared
- Hostile
- Enthusiastic
- Proud
- Irritable
- Alert
- Ashamed
- Inspired
- Nervous
- Determined
- Attentive
- Jittery
- Active
- Afraid
Measured: Measured 1-5 minutes after entering VR environment at Visit 2
State Anxiety Inventory (SAI) Baseline Visit 1
Answered on a tablet; Read each statement and select the appropriate response to indicate how you feel right now, that is, at this very moment. Do not spend too much time on any one statement, but give the answer which seems to describe your present feelings best.
Answered on a 1-4 scale:
1 Not at all 2 A little 3 Somewhat 4 Very Much So
- I feel calm
- I feel secure
- I feel tense
- I feel strained
- I feel at ease
- I feel upset
- I am presently worrying over possible misfortunes
- I feel satisfied
- I feel frightened
- I feel uncomfortable
- I feel self confident
- I feel nervous
- I feel jittery
- I feel indecisive
- I am relaxed
- I feel content
- I am worried
- I feel confused
- I feel steady
- I feel pleasant
Measured: Measured 5-10 minutes prior to entering VR environment at Visit 1
State Anxiety Inventory (SAI) Baseline Visit 2
Answered on a tablet; Read each statement and select the appropriate response to indicate how you feel right now, that is, at this very moment. Do not spend too much time on any one statement, but give the answer which seems to describe your present feelings best.
Answered on a 1-4 scale:
1 Not at all 2 A little 3 Somewhat 4 Very Much So
- I feel calm
- I feel secure
- I feel tense
- I feel strained
- I feel at ease
- I feel upset
- I am presently worrying over possible misfortunes
- I feel satisfied
- I feel frightened
- I feel uncomfortable
- I feel self confident
- I feel nervous
- I feel jittery
- I feel indecisive
- I am relaxed
- I feel content
- I am worried
- I feel confused
- I feel steady
- I feel pleasant
Measured: Measured 5-10 minutes prior to entering VR environment at Visit 2
State Anxiety Inventory (SAI) Post-VR Visit 1
Answered on a tablet; Read each statement and select the appropriate response to indicate how you feel right now, that is, at this very moment. Do not spend too much time on any one statement, but give the answer which seems to describe your present feelings best.
Answered on a 1-4 scale:
1 Not at all 2 A little 3 Somewhat 4 Very Much So
- I feel calm
- I feel secure
- I feel tense
- I feel strained
- I feel at ease
- I feel upset
- I am presently worrying over possible misfortunes
- I feel satisfied
- I feel frightened
- I feel uncomfortable
- I feel self confident
- I feel nervous
- I feel jittery
- I feel indecisive
- I am relaxed
- I feel content
- I am worried
- I feel confused
- I feel steady
- I feel pleasant
Measured: Measured 1-5 minutes after entering VR environment at Visit 1
State Anxiety Inventory (SAI) Post-VR Visit 2
Answered on a tablet; Read each statement and select the appropriate response to indicate how you feel right now, that is, at this very moment. Do not spend too much time on any one statement, but give the answer which seems to describe your present feelings best.
Answered on a 1-4 scale:
1 Not at all 2 A little 3 Somewhat 4 Very Much So
- I feel calm
- I feel secure
- I feel tense
- I feel strained
- I feel at ease
- I feel upset
- I am presently worrying over possible misfortunes
- I feel satisfied
- I feel frightened
- I feel uncomfortable
- I feel self confident
- I feel nervous
- I feel jittery
- I feel indecisive
- I am relaxed
- I feel content
- I am worried
- I feel confused
- I feel steady
- I feel pleasant
Measured: Measured 1-5 minutes after entering VR environment at Visit 2
Affect and Spatial Experience Scale (ASE)
Answered on a tablet; Participants rate their experience with the virtual reality environment on a -10 to 10 scale with opposite descriptors on either end of the scale and 10 being the most like the stated attribute
- Pleasantness: unpleasant vs. pleasant
- Liveliness: Lifeless vs. lively
- Beauty: ugly vs. beautiful
- Familiarity: Unfamiliar vs. familiar
- Excitement: not exciting vs. exciting
- Novelty: Traditional vs. novel
- Spaciousness: narrow vs. spacious
- Simplicity: Complex vs. simple
- Enclosure: Open vs. closed
- Order: Chaotic vs. ordered
- Lightness: Overwhelming vs. light
- Harmony: Not harmonious vs. harmonious
- Calmness: Stressful vs. calming
- Warmth: Cold vs. warm
- Brightness: Dark vs. bright
- Experience: Bad vs. good
- Comfort: Uncomfortable vs. comfortable
- Naturalness: Artificial vs. natural
- Cheerfulness: Depressing vs. cheerful
- Symmetry: Asymmetrical vs. symmetrical
Measured: Measured 5-10 minutes after the end of meal consumption and VR experience at visit 1
VR Presence Questionnaire Visit 1
Answered on a tablet; participants marked on a visual analog scale from 0-100 how they felt in the VR with 0 being not at all and 100 being very much
- In the virtual world, I had a sense of "being there"
- I felt that the virtual world surrounded me.
- I felt like I was just perceiving pictures.
- I did not feel present in the virtual space.
- I had a sense of acting in the virtual space, rather than operating something from outside.
- I felt present in the virtual space.
- How aware were you of the real world surrounding while navigating in the virtual world? (i.e. sounds, room temperature, other people, etc.)?
- I was not aware of my real environment.
- I still paid attention to the real environment.
- I was completely captivated by the virtual world.
- How real did the virtual world seem to you?
- How much did your experience in the virtual environment seem consistent with your real world experience ?
Measured: Measured once 5-10 minutes after the end of meal consumption and the VR experience at visit 1
VR Presence Questionnaire Visit 2
Answered on a tablet; participants marked on a visual analog scale from 0-100 how they felt in the VR with 0 being not at all and 100 being very much
- In the virtual world, I had a sense of "being there"
- I felt that the virtual world surrounded me.
- I felt like I was just perceiving pictures.
- I did not feel present in the virtual space.
- I had a sense of acting in the virtual space, rather than operating something from outside.
- I felt present in the virtual space.
- How aware were you of the real world surrounding while navigating in the virtual world? (i.e. sounds, room temperature, other people, etc.)?
- I was not aware of my real environment.
- I still paid attention to the real environment.
- I was completely captivated by the virtual world.
- How real did the virtual world seem to you?
- How much did your experience in the virtual environment seem consistent with your real world experience ?
Measured: Measured once 5-10 minutes after the end of meal consumption and the VR experience at visit 2
VR Preference Questionnaire Visit 1
Answered on a tablet; Participants would rank on a 0-8 point scale: for question 1-None, a few minutes, half an hour, one hour, a few hours, a day, a few days, many many days; for questions 2-5-not at all, very slight, slight, slight to moderate, moderate, much, very much, extremely so
- How much time would you like to spend in the virtual environment?
- How much would you try to leave or get out of this place?
- How much would you enjoy exploring around?
- How much would you avoid any looking around or exploration of the space?
- How much would you choose to enter this eating environment?
Measured: Measured once 5-10 minutes after the end of meal consumption and the VR experience at visit 1
VR Preference Questionnaire Visit 2
Answered on a tablet; Participants would rank on a 0-8 point scale: for question 1-None, a few minutes, half an hour, one hour, a few hours, a day, a few days, many many days; for questions 2-5-not at all, very slight, slight, slight to moderate, moderate, much, very much, extremely so
- How much time would you like to spend in the virtual environment?
- How much would you try to leave or get out of this place?
- How much would you enjoy exploring around?
- How much would you avoid any looking around or exploration of the space?
- How much would you choose to enter this eating environment?
Measured: Measured once 5-10 minutes after the end of meal consumption and the VR experience at visit 2
Hair Cortisol
The 3-month concentration of cortisol in the participant's hair will be recorded in picograms per milligram--higher values mean higher stress over the past 3 months.
Measured: Measured once 15 minutes prior to entering VR environment at Visit 1
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted28 Oct 2024
- Study start15 Dec 2024
- Primary completion1 Aug 2025
- Study completion1 Aug 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for HealthyStudies of the same condition, open and under way.
- More trials run by Penn State UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 25 participants (actual)
Sponsor and investigators
- Lead sponsor
- Penn State University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Travis Masterson, Penn State University
- Investigators
- Travis Masterson, Principal investigator, The Pennsylvania State University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06662149
- Sponsor's protocol ID
- STUDY00025849
- Status last verified
- Sep 2025
- First submitted
- 22 Oct 2024
- Last updated
- 4 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 4 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Dining Out in NYC: Using VR to Investigate the Influence of Multisensory Urban Design Factors on Eating Behavior in Emerging Adults
- ClinicalTrials.gov ID
- NCT06662149
- Acronym / sponsor ID
- STUDY00025849
- Conditions
- Healthy
- Keywords
- Virtual Reality, Eating behavior
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 25 participants (actual)
- Lead sponsor
- Penn State UniversityUniversity, hospital or other
- Study start
- 15 Dec 2024 (actual)
- Primary completion
- 1 Aug 2025 (actual)
- Study completion
- 1 Aug 2025 (actual)
- First posted
- 28 Oct 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Many factors influence eating choices among humans (mood, taste, convenience, time of day, etc.). Finding simple ways to decrease food intake or improve food choices could improve weight status and overall health of the general population. The purpose of this study is to see if city and/or nature smells affect human eating behavior within a virtual reality-simulated outdoor café. The researchers of this study believe that a better understanding of how smells affect eating behavior could lead to public guidelines that direct the construction and layout of such outdoor eating environments to better support healthy behaviors.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Pleasant First | Experimental | Other: Pleasant Smell, Other: Unpleasant SmellParticipants will experience the pleasant smell in the participant's first visit and the unpleasant smell in the participant's second visit. |
| Unpleasant First | Experimental | Other: Pleasant Smell, Other: Unpleasant SmellParticipants will experience the unpleasant smell in the participant's first visit and the pleasant smell in the participant's second visit. |
Who may qualify
- Ages
- 18 to 29 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (9 listed)
- Between the ages of 18-29
- Fluent in English
- Free of self-reported food allergies/food sensitivities
- No diagnosis of cognitive or physical disabilities/disorders that may affect appetite or eating behaviors (Examples include Major Depressive Disorder, dementia, or eating disorders)
- No diagnosis of disabilities that may affect sensory proprioception related to virtual reality (Examples include vertigo, epilepsy, and ataxia)
Key exclusion criteria (9 listed)
- Are younger than 18 or older than 29 years of age
- Not fluent in English
- Have self-reported food allergies
- Have a diagnosis of cognitive or physical disabilities that may affect appetite or eating behaviors (Examples include Major Depressive Disorder, dementia, or eating disorders)
- Have a diagnosis of disabilities that may affect sensory proprioception related to virtual reality (Examples include vertigo, epilepsy, and ataxia)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Pleasant SmellThe participants will be in an environment with an assumed pleasant smell while consuming the meal. | Other | Pleasant First, Unpleasant First |
| Unpleasant SmellParticipants will be in an environment with an assumed unpleasant smell while consuming the meal. | Other | Pleasant First, Unpleasant First |
Primary outcome
Food Intake Day 1
Time frame: Measured once 5-10 minutes after the end of meal consumption
Total weight of the meal and individual components of the meal are measured in grams before and after participant consumption. The difference is recorded as the amount consumed by the participant. Grams of food will be converted into kilocalories and reported as energy consumed as well.
Food Intake Day 2
Time frame: Measured 5-10 minutes after the end of meal consumption
Total weight of the meal and individual components of the meal are measured in grams before and after participant consumption. The difference is recorded as the amount consumed by the participant. Grams of food will be converted into kilocalories and reported as energy consumed as well.
Scent Experience Questionnaire (SEQ) Baseline Visit 1
Time frame: Measured 5-10 minutes prior to entering VR environment at Visit 1
Answered on a tablet; Participants respond to questions 1-3 using a visual analog scale with opposite descriptors on each end. Question 4 is open response that will be coded as a positive memory/scent or negative memory/scent. 1. How pleasant or unpleasant is the smell you are experiencing? (low anchor: extremely unpleasant, high anchor: extremely pleasant) 2. How intense is the smell you are experiencing? (low anchor: not detectable, high anchor: very strong) 3. How familiar is the smell you are experiencing? (low anchor: completely unknown, high anchor: extremely familiar) 4. Does the smell you are experiencing remind you of anything? If so, what?
Scent Experience Questionnaire (SEQ) Baseline Visit 2
Time frame: Measured 5-10 minutes prior to entering VR environment at Visit 2
Answered on a tablet; Participants respond to questions 1-3 using a visual analog scale with opposite descriptors on each end. Question 4 is open response that will be coded as a positive memory/scent or negative memory/scent. 1. How pleasant or unpleasant is the smell you are experiencing? (low anchor: extremely unpleasant, high anchor: extremely pleasant) 2. How intense is the smell you are experiencing? (low anchor: not detectable, high anchor: very strong) 3. How familiar is the smell you are experiencing? (low anchor: completely unknown, high anchor: extremely familiar) 4. Does the smell you are experiencing remind you of anything? If so, what?
Scent Experience Questionnaire (SEQ) Post-VR Visit 1
Time frame: Measured 1-5 minutes after entering VR environment at Visit 1
Answered on a tablet; Participants respond to questions 1-3 using a visual analog scale with opposite descriptors on each end. Question 4 is open response that will be coded as a positive memory/scent or negative memory/scent. 1. How pleasant or unpleasant is the smell you are experiencing? (low anchor: extremely unpleasant, high anchor: extremely pleasant) 2. How intense is the smell you are experiencing? (low anchor: not detectable, high anchor: very strong) 3. How familiar is the smell you are experiencing? (low anchor: completely unknown, high anchor: extremely familiar) 4. Does the smell you are experiencing remind you of anything? If so, what?
Scent Experience Questionnaire (SEQ) Post-VR Visit 2
Time frame: Measured 1-5 minutes after entering VR environment at Visit 2
Answered on a tablet; Participants respond to questions 1-3 using a visual analog scale with opposite descriptors on each end. Question 4 is open response that will be coded as a positive memory/scent or negative memory/scent. 1. How pleasant or unpleasant is the smell you are experiencing? (low anchor: extremely unpleasant, high anchor: extremely pleasant) 2. How intense is the smell you are experiencing? (low anchor: not detectable, high anchor: very strong) 3. How familiar is the smell you are experiencing? (low anchor: completely unknown, high anchor: extremely familiar) 4. Does the smell you are experiencing remind you of anything? If so, what?
18 secondary outcomes
Pleasure-Arousal-Dominance (PAD) Survey Baseline Visit 1
Time frame: Measured 5-10 minutes prior to entering VR environment at Visit 1
Pleasure-Arousal-Dominance (PAD) Survey Baseline Visit 2
Time frame: Measured 5-10 minutes prior to entering VR environment at Visit 2
Pleasure-Arousal-Dominance (PAD) Survey Post VR Visit 1
Time frame: Measured 1-5 minutes after entering VR environment at Visit 1
Pleasure-Arousal-Dominance (PAD) Survey Post VR Visit 2
Time frame: Measured 1-5 minutes after entering VR environment at Visit 2
Positive Affect Negative Affect Survey (PANAS) Baseline Visit 1
Time frame: Measured 5-10 minutes prior to entering VR environment at Visit 1
Positive Affect Negative Affect Survey (PANAS) Baseline Visit 2
Time frame: Measured 5-10 minutes prior to entering VR environment at Visit 2
Positive Affect Negative Affect Survey (PANAS) Post-VR Visit 1
Time frame: Measured 1-5 minutes after entering VR environment at Visit 1
Positive Affect Negative Affect Survey (PANAS) Post-VR Visit 2
Time frame: Measured 1-5 minutes after entering VR environment at Visit 2
State Anxiety Inventory (SAI) Baseline Visit 1
Time frame: Measured 5-10 minutes prior to entering VR environment at Visit 1
State Anxiety Inventory (SAI) Baseline Visit 2
Time frame: Measured 5-10 minutes prior to entering VR environment at Visit 2
State Anxiety Inventory (SAI) Post-VR Visit 1
Time frame: Measured 1-5 minutes after entering VR environment at Visit 1
State Anxiety Inventory (SAI) Post-VR Visit 2
Time frame: Measured 1-5 minutes after entering VR environment at Visit 2
Affect and Spatial Experience Scale (ASE)
Time frame: Measured 5-10 minutes after the end of meal consumption and VR experience at visit 1
VR Presence Questionnaire Visit 1
Time frame: Measured once 5-10 minutes after the end of meal consumption and the VR experience at visit 1
VR Presence Questionnaire Visit 2
Time frame: Measured once 5-10 minutes after the end of meal consumption and the VR experience at visit 2
VR Preference Questionnaire Visit 1
Time frame: Measured once 5-10 minutes after the end of meal consumption and the VR experience at visit 1
VR Preference Questionnaire Visit 2
Time frame: Measured once 5-10 minutes after the end of meal consumption and the VR experience at visit 2
Hair Cortisol
Time frame: Measured once 15 minutes prior to entering VR environment at Visit 1
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Sep 2025.
- Individual participant dataSharing planned: No
Related trials for Healthy
Active, not recruitingObservational study
SCIVAX: Biomarkers of Immune Dysfunction and Vaccine Responsiveness in Chronic SCI
Spinal Cord Injuries, Traumatic Spinal Cord Injury
Recruiting
Effects of a Hemp Seed-based Product on Appetite and Health Parameters
Healthy
RecruitingPhase 1
A Study of INI-822 in Healthy Volunteers and Participants With Metabolic Dysfunction-Associated Steatohepatitis (MASH) or Presumed MASH
Metabolic Dysfunction-Associated Steatohepatitis
Not yet recruitingPhase 1
Phase I Trial of High-Density Theta Burst Stimulation (hdTBS)
Healthy Volunteers
Not yet recruiting
Stearic Acid and Endothelial Function
Healthy Middle-aged Subjects, Obesity & Overweight
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Travis Masterson principal investigator
The Pennsylvania State University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Pleasant Smell and Unpleasant Smell in people with Healthy, run by Penn State University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 9 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 4 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Food Intake Day 1 (time frame: Measured once 5-10 minutes after the end of meal consumption). The study lists 6 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Sep 2025.