Cervical RadiculopathyNCT06663592
Efficacy of Adding Neural Mobilization Techniques in Patients With Cervical Radiculopathy
A study testing Conventional treatment, Tensioner Neuro Dynamic Mobilization and Slider Neuro Dynamic Mobilization in people with Cervical Radiculopathy and Neuromobılızatıon, run by Cairo University at 1 site in Egypt.
Trial summary
The goal of this randomized controlled trial is to investigate the effects of adding slider neural mobilization technique compared to tensioner neural mobilization technique to conventional physical therapy treatment on pain, function, cervical range of motion, hand grip strength, and electrophysiological parameters… Read more about this study
- Who is it for?
- Ages 30 to 50 years
- Conditions the study is for
- Cervical Radiculopathy, Neuromobılızatıon, Median Nerve
- What is being tested?
- Conventional treatment, Tensioner Neuro Dynamic Mobilization and Slider Neuro Dynamic Mobilization
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 36 participants
- Where
- 1 siteEgypt
- Study dates
- 15 Nov 2024to 15 Apr 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 30 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- Current continuous or intermittent pain that has persisted for more than 3 months.
- Motor, reflex, and/or sensory changes in the upper limb.
- Both genders aged 30-50 years.
- Three positive special tests out of five as a predefined diagnostic criterion from the following tests: Upper Limb Neural Tension A (ULNT) test for the median nerve, Spurling's test, compression test, cervical distraction test, less than 60° cervical rotation towards the symptomatic side, and Valsalva maneuver.
- A motor nerve conduction study, F wave, and H reflex were performed in the involved limb to confirm CR.
Who cannot join
- History of surgical procedures for cervical or upper extremity.
- Clinical signs or symptoms of medical red flags (infection, cancer, and cardiac involvement).
- Patients with neck pain for signs and symptoms of serious pathology, upper cervical ligamentous insufficiency, unexplained cranial nerve dysfunction, and spinal fractures.
- Any systematic disease such as rheumatism and tuberculosis, cervical myelopathy, or multiple sclerosis.
- Systemic disease is known to cause generalized peripheral neuropathy, such as diabetes mellitus.
- Complete loss of sensation along the involved nerve root.
Show all 9Show fewer
- Upper limb compression syndrome, such as thoracic outlet syndrome, carpal tunnel syndrome, and pronator syndrome.
- Pregnant woman.
- Patients who have received any physical therapy of the cervical region in the past 3 months.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Effectiveness of Slider and Tensioner Neurodynamic Mobilization Techniques in Patients With Cervical Radiculopathy: A Randomized Controlled Trial
The goal of this randomized controlled trial is to investigate the effects of adding slider neural mobilization technique compared to tensioner neural mobilization technique to conventional physical therapy treatment on pain, function, cervical range of motion, hand grip strength, and electrophysiological parameters of the median nerve in patients with cervical radiculopathy.
Read the detailed description
Cervical radiculopathy (CR) is a condition where the nerve root of a spinal nerve is compressed or impaired, causing the pain and symptoms to spread beyond the neck, radiating to the shoulder, and upper limb. Cervical radiculopathy primarily results from an impingement and inflammation of a nerve root induced by a space-occupying lesion that reduces the size of the intervertebral foramen, as a degenerative lesion of the zygapophyseal joint, or it is associated with a cervical disc derangement.
Patients presenting with CR complain of neck, periscapular, and radicular pain into the hand and arm. As well as neurologic symptoms such as sensory disturbances (paresthesia or numbness), muscle weakness with reduced tendon reflexes in the affected nerve root, or a combination of these signs and symptoms.
The reported annual incidence of CR is 85 cases per 100,000 people in the population, while the prevalence is 3.5/1000 persons. The C7 nerve root is most frequently impacted, with more than half of all cases affecting this level.
Several studies utilized therapeutic exercises, manual therapy, other modalities, cervical collars, cervical traction, postural education, and different medications such as drugs and steroid injections in the conservative management for cervical radiculopathy in its different stages.
The neural mobilization (NM) is a manual therapy method that improves neural flexibility, lowers dynamic sensitivity of the nervous system, increases blood flow, and relieves pain; for that, improved neural mobility and alleviated pain increase joint range of motion (ROM).
The NM techniques are delivered by two techniques, "sliding/gliding" and "tensioning." Tensioner technique generate tension from both ends of the nerve, while sliders involve gliding of the nerve relative to its surrounding structures by performing joint movements that elongate the nerve bed with minimal strain. In addition, sliders are usually less aggressive than tensioners, and their use might be indicated at early disease stages.
Both techniques aid in preventing the formation of adhesions, reducing endoneurial pressure, reducing intraneural edema, increasing nerve oxygenation, and decreasing ischemic pain.
Studies that used sliders and tensioners techniques in their clinical studies showed significant changes in biomechanical factors such as patients' self-reports of pain, disability, ROM, endurance, and muscle strength in the management of musculoskeletal neck disorders with nerve-related symptoms.
Therefore, what are the possible effects of adding the tensioner neural mobilization technique versus the slider neural mobilization technique to conventional physical treatment in treating patients with cervical radiculopathy?
- Conditions
- Cervical Radiculopathy, Neuromobılızatıon, Median Nerve, Electromyography, Nerve Conduction
- Being tested
- Conventional treatment, Tensioner Neuro Dynamic Mobilization, Slider Neuro Dynamic Mobilization
- Medical subject headings
- Radiculopathy
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Conventional treatmentOther
hot pack, stretching of the neck muscles, cervical isometrics exercise
Tensioner Neuro Dynamic MobilizationOther
Median nerve tensioner neural mobilization with addition to conventional treatment
Slider Neuro Dynamic MobilizationOther
Median nerve neural sliding mobilization with addition to conventional treatment
| Study group | Role | What they receive |
|---|---|---|
| Control group A (conventional treatment) | Active comparator | Conventional treatment, including hot pack, stretching of the neck muscles, cervical isometrics exercise. Receives: Other: Conventional treatment |
| Experimental group B (Tensioning neural mobilization with addition to conventional treatment) | Experimental | Median nerve neural tensioning mobilization with addition to conventional treatment Receives: Other: Tensioner Neuro Dynamic Mobilization |
| Experimental group C (Sliding neural mobilization with addition to conventional treatment) | Experimental | Median nerve sliding neural mobilization with addition to conventional treatment Receives: Other: Slider Neuro Dynamic Mobilization |
What is being measured
The primary outcome is the main question the study is designed to answer.
Visual Analogue Scale
to measure neck pain with score extended from 0 to 10, minimum score 0 (no pain), highest score 10 (worst pain).
Measured: At baseline, to the end of treatment at 4 weeks.
The Arabic Version Of Neck Disability Index
to assess the level of disabilities in patients with neck pain, in % points.
Measured: At baseline, to the end of treatment at 4 weeks.
Cervical Range of Motion
to measure the full cervical rotation using CROM device in degrees
Measured: At baseline, to the end of treatment at 4 weeks.
Hand Grip Strength
to measure hand grip strength using hydraulic dynamometer, in kilogram.
Measured: At baseline, to the end of treatment at 4 weeks.
Nerve Conduction Study
Motor conduction study for the median nerve, to measure conduction velocity (m/second), distal latency (ms), and amplitude(mV).
Measured: At baseline, to the end of treatment at 4 weeks.
F wave
F wave for the median nerve to measure latency (ms).
Measured: At baseline, to the end of treatment at 4 weeks.
H-Reflex
H-Reflex for the median nerve to measure latency (ms), amplitude (mV), H-R ratio (%).
Measured: At baseline, to the end of treatment at 4 weeks.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Oct 2024
- Study start15 Nov 2024
- Primary completion15 Mar 2025
- Study completion15 Apr 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (74)Papers the sponsor has linked to this study.
- Other trials for Cervical RadiculopathyStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 36 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Hiba Mohammad Hasan, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06663592
- Sponsor's protocol ID
- P.T.REC/012/005270
- Status last verified
- Apr 2026
- First submitted
- 21 Oct 2024
- Last updated
- 9 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Abrams RA, Butler JM, Bodine-Fowler S, Botte MJ. Tensile properties of the neurorrhaphy site in the rat sciatic nerve. J Hand Surg Am. 1998 May;23(3):465-70. doi: 10.1016/S0363-5023(05)80464-2.
PubMed 9620187Adams MA, Dolan P. A technique for quantifying the bending moment acting on the lumbar spine in vivo. J Biomech. 1991;24(2):117-26. doi: 10.1016/0021-9290(91)90356-r.
PubMed 2037611Alharmoodi BY, Arumugam A, Ahbouch A, Moustafa IM. Comparative effects of tensioning and sliding neural mobilization on peripheral and autonomic nervous system function: A randomized controlled trial. Hong Kong Physiother J. 2022 Jun;42(1):41-53. doi: 10.1142/S1013702522500056. Epub 2022 Mar 17.
PubMed 35782695Audette I, Dumas JP, Cote JN, De Serres SJ. Validity and between-day reliability of the cervical range of motion (CROM) device. J Orthop Sports Phys Ther. 2010 May;40(5):318-23. doi: 10.2519/jospt.2010.3180.
PubMed 20436238Basson A, Olivier B, Ellis R, Coppieters M, Stewart A, Mudzi W. The Effectiveness of Neural Mobilization for Neuromusculoskeletal Conditions: A Systematic Review and Meta-analysis. J Orthop Sports Phys Ther. 2017 Sep;47(9):593-615. doi: 10.2519/jospt.2017.7117. Epub 2017 Jul 13.
PubMed 28704626Beaton DE, O'Driscoll SW, Richards RR. Grip strength testing using the BTE work simulator and the Jamar dynamometer: a comparative study. Baltimore Therapeutic Equipment. J Hand Surg Am. 1995 Mar;20(2):293-8. doi: 10.1016/s0363-5023(05)80029-2.
PubMed 7775773Bland JH, Boushey DR. Anatomy and physiology of the cervical spine. Semin Arthritis Rheum. 1990 Aug;20(1):1-20. doi: 10.1016/0049-0172(90)90090-3.
PubMed 2218549Bogduk N, Mercer S. Biomechanics of the cervical spine. I: Normal kinematics. Clin Biomech (Bristol). 2000 Nov;15(9):633-48. doi: 10.1016/s0268-0033(00)00034-6.
PubMed 10946096Boyles R, Toy P, Mellon J Jr, Hayes M, Hammer B. Effectiveness of manual physical therapy in the treatment of cervical radiculopathy: a systematic review. J Man Manip Ther. 2011 Aug;19(3):135-42. doi: 10.1179/2042618611Y.0000000011.
PubMed 22851876Burke FD, Ellis J, McKenna H, Bradley MJ. Primary care management of carpal tunnel syndrome. Postgrad Med J. 2003 Aug;79(934):433-7. doi: 10.1136/pmj.79.934.433.
PubMed 12954952ISBN 0975091026
Carette S, Fehlings MG. Clinical practice. Cervical radiculopathy. N Engl J Med. 2005 Jul 28;353(4):392-9. doi: 10.1056/NEJMcp043887. No abstract available.
PubMed 16049211Carlesso LC, Macdermid JC, Gross AR, Walton DM, Santaguida PL. Treatment preferences amongst physical therapists and chiropractors for the management of neck pain: results of an international survey. Chiropr Man Therap. 2014 Mar 24;22(1):11. doi: 10.1186/2045-709X-22-11.
PubMed 24661461Cattrysse E, Barbero M, Kool P, Gagey O, Clarys JP, Van Roy P. 3D morphometry of the transverse and alar ligaments in the occipito-atlanto-axial complex: an in vitro analysis. Clin Anat. 2007 Nov;20(8):892-8. doi: 10.1002/ca.20559.
PubMed 17948286Christie AD, Inglis JG, Boucher JP, Gabriel DA. Reliability of the FCR H-reflex. J Clin Neurophysiol. 2005 Jun;22(3):204-9.
PubMed 15933493
Study at a glance
From the registry record, last updated by the sponsor on 9 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of Slider and Tensioner Neurodynamic Mobilization Techniques in Patients With Cervical Radiculopathy: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT06663592
- Acronym / sponsor ID
- P.T.REC/012/005270
- Conditions
- Cervical Radiculopathy, Neuromobılızatıon, Median Nerve, Electromyography, Nerve Conduction
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 36 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 15 Nov 2024 (actual)
- Primary completion
- 15 Mar 2025 (actual)
- Study completion
- 15 Apr 2025 (actual)
- First posted
- 29 Oct 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this randomized controlled trial is to investigate the effects of adding slider neural mobilization technique compared to tensioner neural mobilization technique to conventional physical therapy treatment on pain, function, cervical range of motion, hand grip strength, and electrophysiological parameters of the median nerve in patients with cervical radiculopathy.
Detailed description
Cervical radiculopathy (CR) is a condition where the nerve root of a spinal nerve is compressed or impaired, causing the pain and symptoms to spread beyond the neck, radiating to the shoulder, and upper limb. Cervical radiculopathy primarily results from an impingement and inflammation of a nerve root induced by a space-occupying lesion that reduces the size of the intervertebral foramen, as a degenerative lesion of the zygapophyseal joint, or it is associated with a cervical disc derangement.
Patients presenting with CR complain of neck, periscapular, and radicular pain into the hand and arm. As well as neurologic symptoms such as sensory disturbances (paresthesia or numbness), muscle weakness with reduced tendon reflexes in the affected nerve root, or a combination of these signs and symptoms.
The reported annual incidence of CR is 85 cases per 100,000 people in the population, while the prevalence is 3.5/1000 persons. The C7 nerve root is most frequently impacted, with more than half of all cases affecting this level.
Several studies utilized therapeutic exercises, manual therapy, other modalities, cervical collars, cervical traction, postural education, and different medications such as drugs and steroid injections in the conservative management for cervical radiculopathy in its different stages.
The neural mobilization (NM) is a manual therapy method that improves neural flexibility, lowers dynamic sensitivity of the nervous system, increases blood flow, and relieves pain; for that, improved neural mobility and alleviated pain increase joint range of motion (ROM).
The NM techniques are delivered by two techniques, "sliding/gliding" and "tensioning." Tensioner technique generate tension from both ends of the nerve, while sliders involve gliding of the nerve relative to its surrounding structures by performing joint movements that elongate the nerve bed with minimal strain. In addition, sliders are usually less aggressive than tensioners, and their use might be indicated at early disease stages.
Both techniques aid in preventing the formation of adhesions, reducing endoneurial pressure, reducing intraneural edema, increasing nerve oxygenation, and decreasing ischemic pain.
Studies that used sliders and tensioners techniques in their clinical studies showed significant changes in biomechanical factors such as patients' self-reports of pain, disability, ROM, endurance, and muscle strength in the management of musculoskeletal neck disorders with nerve-related symptoms.
Therefore, what are the possible effects of adding the tensioner neural mobilization technique versus the slider neural mobilization technique to conventional physical treatment in treating patients with cervical radiculopathy?
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Control group A (conventional treatment) | Active comparator | Other: Conventional treatmentConventional treatment, including hot pack, stretching of the neck muscles, cervical isometrics exercise. |
| Experimental group B (Tensioning neural mobilization with addition to conventional treatment) | Experimental | Other: Tensioner Neuro Dynamic MobilizationMedian nerve neural tensioning mobilization with addition to conventional treatment |
| Experimental group C (Sliding neural mobilization with addition to conventional treatment) | Experimental | Other: Slider Neuro Dynamic MobilizationMedian nerve sliding neural mobilization with addition to conventional treatment |
Who may qualify
- Ages
- 30 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Current continuous or intermittent pain that has persisted for more than 3 months.
- Motor, reflex, and/or sensory changes in the upper limb.
- Both genders aged 30-50 years.
- Three positive special tests out of five as a predefined diagnostic criterion from the following tests: Upper Limb Neural Tension A (ULNT) test for the median nerve, Spurling's test, compression test, cervical distraction test, less than 60° cervical rotation towards the symptomatic side, and Valsalva maneuver.
- A motor nerve conduction study, F wave, and H reflex were performed in the involved limb to confirm CR.
Key exclusion criteria (9 listed)
- History of surgical procedures for cervical or upper extremity.
- Clinical signs or symptoms of medical red flags (infection, cancer, and cardiac involvement).
- Patients with neck pain for signs and symptoms of serious pathology, upper cervical ligamentous insufficiency, unexplained cranial nerve dysfunction, and spinal fractures.
- Any systematic disease such as rheumatism and tuberculosis, cervical myelopathy, or multiple sclerosis.
- Systemic disease is known to cause generalized peripheral neuropathy, such as diabetes mellitus.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Conventional treatmenthot pack, stretching of the neck muscles, cervical isometrics exercise | Other | Control group A (conventional treatment) |
| Tensioner Neuro Dynamic MobilizationMedian nerve tensioner neural mobilization with addition to conventional treatment | Other | Experimental group B (Tensioning neural mobilization with addition to conventional treatment) |
| Slider Neuro Dynamic MobilizationMedian nerve neural sliding mobilization with addition to conventional treatment | Other | Experimental group C (Sliding neural mobilization with addition to conventional treatment) |
Primary outcome
Visual Analogue Scale
Time frame: At baseline, to the end of treatment at 4 weeks.
to measure neck pain with score extended from 0 to 10, minimum score 0 (no pain), highest score 10 (worst pain).
The Arabic Version Of Neck Disability Index
Time frame: At baseline, to the end of treatment at 4 weeks.
to assess the level of disabilities in patients with neck pain, in % points.
Cervical Range of Motion
Time frame: At baseline, to the end of treatment at 4 weeks.
to measure the full cervical rotation using CROM device in degrees
Hand Grip Strength
Time frame: At baseline, to the end of treatment at 4 weeks.
to measure hand grip strength using hydraulic dynamometer, in kilogram.
Nerve Conduction Study
Time frame: At baseline, to the end of treatment at 4 weeks.
Motor conduction study for the median nerve, to measure conduction velocity (m/second), distal latency (ms), and amplitude(mV).
F wave
Time frame: At baseline, to the end of treatment at 4 weeks.
F wave for the median nerve to measure latency (ms).
H-Reflex
Time frame: At baseline, to the end of treatment at 4 weeks.
H-Reflex for the median nerve to measure latency (ms), amplitude (mV), H-R ratio (%).
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Apr 2026.
- Background: PubMed 9620187Abrams RA, Butler JM, Bodine-Fowler S, Botte MJ. Tensile properties of the neurorrhaphy site in the rat sciatic nerve. J Hand Surg Am. 1998 May;23(3):465-70. doi: 10.1016/S0363-5023(05)80464-2.
- Background: PubMed 2037611Adams MA, Dolan P. A technique for quantifying the bending moment acting on the lumbar spine in vivo. J Biomech. 1991;24(2):117-26. doi: 10.1016/0021-9290(91)90356-r.
- Background: PubMed 35782695Alharmoodi BY, Arumugam A, Ahbouch A, Moustafa IM. Comparative effects of tensioning and sliding neural mobilization on peripheral and autonomic nervous system function: A randomized controlled trial. Hong Kong Physiother J. 2022 Jun;42(1):41-53. doi: 10.1142/S1013702522500056. Epub 2022 Mar 17.
- Background: PubMed 20436238Audette I, Dumas JP, Cote JN, De Serres SJ. Validity and between-day reliability of the cervical range of motion (CROM) device. J Orthop Sports Phys Ther. 2010 May;40(5):318-23. doi: 10.2519/jospt.2010.3180.
- Background: PubMed 28704626Basson A, Olivier B, Ellis R, Coppieters M, Stewart A, Mudzi W. The Effectiveness of Neural Mobilization for Neuromusculoskeletal Conditions: A Systematic Review and Meta-analysis. J Orthop Sports Phys Ther. 2017 Sep;47(9):593-615. doi: 10.2519/jospt.2017.7117. Epub 2017 Jul 13.
- Background: PubMed 7775773Beaton DE, O'Driscoll SW, Richards RR. Grip strength testing using the BTE work simulator and the Jamar dynamometer: a comparative study. Baltimore Therapeutic Equipment. J Hand Surg Am. 1995 Mar;20(2):293-8. doi: 10.1016/s0363-5023(05)80029-2.
- Background: PubMed 2218549Bland JH, Boushey DR. Anatomy and physiology of the cervical spine. Semin Arthritis Rheum. 1990 Aug;20(1):1-20. doi: 10.1016/0049-0172(90)90090-3.
- Background: PubMed 10946096Bogduk N, Mercer S. Biomechanics of the cervical spine. I: Normal kinematics. Clin Biomech (Bristol). 2000 Nov;15(9):633-48. doi: 10.1016/s0268-0033(00)00034-6.
- Background: PubMed 22851876Boyles R, Toy P, Mellon J Jr, Hayes M, Hammer B. Effectiveness of manual physical therapy in the treatment of cervical radiculopathy: a systematic review. J Man Manip Ther. 2011 Aug;19(3):135-42. doi: 10.1179/2042618611Y.0000000011.
- Background: PubMed 12954952Burke FD, Ellis J, McKenna H, Bradley MJ. Primary care management of carpal tunnel syndrome. Postgrad Med J. 2003 Aug;79(934):433-7. doi: 10.1136/pmj.79.934.433.
- BackgroundISBN 0975091026
- Background: PubMed 16049211Carette S, Fehlings MG. Clinical practice. Cervical radiculopathy. N Engl J Med. 2005 Jul 28;353(4):392-9. doi: 10.1056/NEJMcp043887. No abstract available.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Conventional treatment, Tensioner Neuro Dynamic Mobilization and Slider Neuro Dynamic Mobilization in people with Cervical Radiculopathy and Neuromobılızatıon, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 9 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Visual Analogue Scale (time frame: At baseline, to the end of treatment at 4 weeks.). The study lists 7 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06663592, which also lists 74 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Apr 2026.