Cervical SpondylosisNCT06664931
Muscle Energy Versus Mulligan Techniques in Treating Patients With Cervical Spondylosis
A study testing Group (A) Muscle Energy Technique (MET) and Group (B) Mulligan Mobilizations Techniques (MMT). in people with Cervical Spondylosis and Mulligan Mobilization, run by Cairo University at 1 site in Egypt.
Trial summary
This study will be aimed to answer the following questions: Which technique, MET or MMT, is more effective in reducing pain, increasing range of motion (ROM), improving proprioception, and enhancing functional ability in individuals with CS? It will be assumed that: 1. Read more about this study
- Who is it for?
- Ages 40 to 60 yearsHealthy volunteers can take part
- Conditions the study is for
- Cervical Spondylosis, Mulligan Mobilization, SNAGs
- What is being tested?
- Group (A) Muscle Energy Technique (MET) and Group (B) Mulligan Mobilizations Techniques (MMT).
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 40 participants
- Where
- 1 siteEgypt
- Study dates
- 5 Nov 2024to 1 Feb 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 60 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Participants of both genders aged 40 - 60 years old, diagnosed with clinically and medically stable CS.
- All participants will be assessed and referred by orthopedic surgeons before starting the study.
- Mechanical neck pain localized to the cervical.
- Neck pain lasting more than 3 months, local tenderness of the upper fibers of the trapezius, limitation in cervical ROM and muscle spasm.
- Moderate pain intensity (45-74 mm on VAS).
- Participants with Moderate pain intensity NDI (30 - 48%).
- All participants are free from any pathological conditions that might influence the results.
Who cannot join
- Participants with systemic diseases like rheumatoid arthritis, metabolic diseases, or osteoporosis.
- History of trauma or accidental injuries to the cervical spine.
- Cervical myelopathy, inflammatory arthritis, tumors, infections involving the cervical spine, or vertebrobasilar artery insufficiency.
- Cervical spine injury, dizziness, vertigo, or any other musculoskeletal complaints.
Trial locations and contacts
1 site in 1 country.
About this study
This study will be aimed to answer the following questions:
Which technique, MET or MMT, is more effective in reducing pain, increasing range of motion (ROM), improving proprioception, and enhancing functional ability in individuals with CS?
It will be assumed that:
- All participants will adhere to study instructions and procedures.
- All participants will be evaluated under standardized conditions.
Read the detailed description
Cervical spondylosis (CS) is a highly prevalent age-related condition (95%), that affects the joints and discs of the cervical spine. By age 65, nearly all individuals experience some degree of degeneration, characterized by disc breakdown and enlarged facet joints. While aging is the primary cause, injuries can accelerate this process in younger populations.
Significance of the Study Age-related degenerative spinal changes are almost widespread. Population-based studies have shown that approximately 80 to 90% of people have disk degeneration on magnetic resonance imaging (MRI) by the age of 50 years.
A global burden review estimates that over 300 million people worldwide had mechanical neck pain lasting at least 3 months in 2015.
Clinical features of spondylosis are more common in men than in women, with a peak incidence between the ages of 40 and 60 years for both men and women.
Cervical spondylosis commonly affects the middle and lower cervical vertebrae (C5-C6 and C6-C7), although higher levels may also be involved. Neck pain is the most prominent symptom. CS can affect all cervical components (i.e., the spinal cord, spinal vasculature, and nerve roots). Cervical spondylosis Symptoms include cervical instability (abnormal movement or laxity between vertebrae). This instability can lead to various symptoms such as neck pain, muscle imbalance between cervical and shoulder girdle muscles (weakness in cervical flexors, lower trapezius, and anterior serratus; tightness in the upper trapezius, scapular lift, and pectoralis major), disc herniation and osteophyte formation. These can compromise proprioception (accurate sensory feedback) and limit neck mobility, significantly impacting function and daily activities.
Muscle energy techniques is a form of manual therapy frequently used by physical therapists to improve musculoskeletal function and alleviate pain. MET aims to adjust abnormal muscle tone by training specific muscles, enhancing strength and stability, improving the musculoskeletal function, and ultimately improving quality of life.
Another treatment technique is MMT that is now an integral component of many manual physiotherapists' clinical practice. MMT involves sustained passive accessory force/glide to a joint while the participant actively performs a problematic movement.
This study aims to address this gap in knowledge by investigating whether MET or MMT is more effective in improving pain, ROM, proprioception, and functional ability in individuals with cervical spondylosis. The findings from this study can provide valuable insights for physical therapists in selecting the most appropriate treatment approach for their patients with cervical spondylosis. By determining the more effective technique, physical therapists can optimize treatment plans and potentially improve patient outcomes.
This Triple-blinded (the examiner, statistician, and the participants will be blinded, while the therapist will be aware of treatment procedures) randomized controlled trial (RCT) will investigate the effectiveness of Muscle Energy Techniques (MET) compared to Mulligan Mobilization Techniques (MMT) on cervical spine pain, ROM, and function in participants with Cervical Spondylosis (CS). The study will be conducted at the outpatient physical therapy clinic of Horus University in New Damietta, Egypt.
- Conditions
- Cervical Spondylosis, Mulligan Mobilization, SNAGs, Muscle Energy Technique, Post Isometric Relaxation
- Being tested
- Group (A) Muscle Energy Technique (MET), Group (B) Mulligan Mobilizations Techniques (MMT).
- Keywords
- Mulligan Mobilization, Mobilization with Movement, SNAGs, Muscle Energy Technique, Post isometric relaxation, Cervical Spondylosis
- Medical subject headings
- Spondylosis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Group (A) Muscle Energy Technique (MET)Other
Also called Post Isometric Relaxation
MET will be applied to three key muscles commonly associated with neck pain:
upper trapezius, levator scapulae, and anterior scalenus.
Group (B) Mulligan Mobilizations Techniques (MMT).Other
Also called SNAGs
Participants in Group (B) will receive MMT alongside the traditional treatment. MMT utilizes a specific technique called Sustained Natural Apophyseal Glides (SNAGs) to improve joint mobilization.
| Study group | Role | What they receive |
|---|---|---|
| Group (A) Muscle Energy Technique (MET). | Experimental | These participants will receive METs, in addition to a standard physical therapy program consisting of deep neck flexor strengthening exercises, isometric exercise, and range of motion exercises (3 sessions per week for 4 weeks). Receives: Other: Group (A) Muscle Energy Technique (MET) |
| Group (B) Mulligan Mobilization Technique group (MMT). | Experimental | Participants will receive MMT interventions alongside the standard physical therapy program deep neck flexor strengthening exercises, isometric exercise, and range of motion exercises 3 sessions per week for 4 weeks. Receives: Other: Group (B) Mulligan Mobilizations Techniques (MMT). |
What is being measured
The primary outcome is the main question the study is designed to answer.
Cervical Range of Motion (CROM)
to measure the Cervical ROM for (Flexion, Extension, Rotation for both sides and Sidebending for both sides) and proprioception (Neutral head position test, and Target head position)
Measured: Pre- intervention and after 4 weeks of treatment
The Arabic Version Of Neck Disability Index (NDI).
to assess the level of disabilities in patients with neck pain, in % points
Measured: Pre- intervention and after 4 weeks of treatment
Visual Analogue Scale (VAS).
to measure neck pain with score extended from 0 to 10, minimum score 0 (no pain), highest score 10 (worst pain).
Measured: Pre- intervention and after 4 weeks of treatment
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Oct 2024
- Study start5 Nov 2024
- Primary completion1 Jan 2025
- Study completion1 Feb 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (57)Papers the sponsor has linked to this study.
- Other trials for Cervical SpondylosisStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Model Description
- Masking
- Double blind
- Who is masked
- Investigator, Outcomes assessor
- Enrolment
- 40 participants (actual)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Mohamed Ahmed Badier Elkomy, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06664931
- Sponsor's protocol ID
- P.T.REC/012/005271
- Status last verified
- Jul 2025
- First submitted
- 28 Oct 2024
- Last updated
- 16 Jul 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Binch AL, Cole AA, Breakwell LM, Michael AL, Chiverton N, Creemers LB, Cross AK, Le Maitre CL. Nerves are more abundant than blood vessels in the degenerate human intervertebral disc. Arthritis Res Ther. 2015 Dec 21;17:370. doi: 10.1186/s13075-015-0889-6.
PubMed 26695177Manzoor A, Anwar N, Khalid K, Haider R, Saghir M, Javed MA. Comparison of effectiveness of muscle energy technique with Mulligan mobilization in patients with non-specific neck pain. J Pak Med Assoc. 2021 Jun;71(6):1532-1524. doi: 10.47391/JPMA.981.
PubMed 34111066Atisook R, Euasobhon P, Saengsanon A, Jensen MP. Validity and Utility of Four Pain Intensity Measures for Use in International Research. J Pain Res. 2021 Apr 21;14:1129-1139. doi: 10.2147/JPR.S303305. eCollection 2021.
PubMed 33907460Audette I, Dumas JP, Cote JN, De Serres SJ. Validity and between-day reliability of the cervical range of motion (CROM) device. J Orthop Sports Phys Ther. 2010 May;40(5):318-23. doi: 10.2519/jospt.2010.3180.
PubMed 20436238Bagcaci S, Unuvar BS, Gercek H, Ugurlu I, Sert OA, Yilmaz K. A randomized controlled trial on pain, grip strength, and functionality in lateral elbow pain: Mulligan vs muscle energy techniques. J Back Musculoskelet Rehabil. 2023;36(2):419-427. doi: 10.3233/BMR-220061.
PubMed 36120766Bakhsheshian J, Mehta VA, Liu JC. Current Diagnosis and Management of Cervical Spondylotic Myelopathy. Global Spine J. 2017 Sep;7(6):572-586. doi: 10.1177/2192568217699208. Epub 2017 May 31.
PubMed 28894688Baron EM, Young WF. Cervical spondylotic myelopathy: a brief review of its pathophysiology, clinical course, and diagnosis. Neurosurgery. 2007 Jan;60(1 Supp1 1):S35-41. doi: 10.1227/01.NEU.0000215383.64386.82.
PubMed 17204884Binder AI. Cervical spondylosis and neck pain. BMJ. 2007 Mar 10;334(7592):527-31. doi: 10.1136/bmj.39127.608299.80. No abstract available.
PubMed 17347239Bono CM, Ghiselli G, Gilbert TJ, Kreiner DS, Reitman C, Summers JT, Baisden JL, Easa J, Fernand R, Lamer T, Matz PG, Mazanec DJ, Resnick DK, Shaffer WO, Sharma AK, Timmons RB, Toton JF; North American Spine Society. An evidence-based clinical guideline for the diagnosis and treatment of cervical radiculopathy from degenerative disorders. Spine J. 2011 Jan;11(1):64-72. doi: 10.1016/j.spinee.2010.10.023.
PubMed 21168100Brinjikji W, Luetmer PH, Comstock B, Bresnahan BW, Chen LE, Deyo RA, Halabi S, Turner JA, Avins AL, James K, Wald JT, Kallmes DF, Jarvik JG. Systematic literature review of imaging features of spinal degeneration in asymptomatic populations. AJNR Am J Neuroradiol. 2015 Apr;36(4):811-6. doi: 10.3174/ajnr.A4173. Epub 2014 Nov 27.
PubMed 25430861Buyukturan O, Buyukturan B, Sas S, Kararti C, Ceylan I. The Effect of Mulligan Mobilization Technique in Older Adults with Neck Pain: A Randomized Controlled, Double-Blind Study. Pain Res Manag. 2018 May 15;2018:2856375. doi: 10.1155/2018/2856375. eCollection 2018.
PubMed 29861800Cheung J, Kajaks T, Macdermid JC. The relationship between neck pain and physical activity. Open Orthop J. 2013 Sep 20;7:521-9. doi: 10.2174/1874325001307010521. eCollection 2013.
PubMed 24133553Copurgensli C, Gur G, Tunay VB. A comparison of the effects of Mulligan's mobilization and Kinesio taping on pain, range of motion, muscle strength, and neck disability in patients with Cervical Spondylosis: A randomized controlled study. J Back Musculoskelet Rehabil. 2017;30(1):51-62. doi: 10.3233/BMR-160713.
PubMed 27257980Delgado DA, Lambert BS, Boutris N, McCulloch PC, Robbins AB, Moreno MR, Harris JD. Validation of Digital Visual Analog Scale Pain Scoring With a Traditional Paper-based Visual Analog Scale in Adults. J Am Acad Orthop Surg Glob Res Rev. 2018 Mar 23;2(3):e088. doi: 10.5435/JAAOSGlobal-D-17-00088. eCollection 2018 Mar.
PubMed 30211382Dong WK, Lin XH. [Clinical observation on cervical spondylosis of neck type treated with acupuncture at original and terminal points of trapezius]. Zhongguo Zhen Jiu. 2012 Mar;32(3):211-4. Chinese.
PubMed 22471131
Study at a glance
From the registry record, last updated by the sponsor on 16 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Muscle Energy Versus Mulligan Techniques in Treating Patients With Cervical Spondylosis
- ClinicalTrials.gov ID
- NCT06664931
- Acronym / sponsor ID
- P.T.REC/012/005271
- Conditions
- Cervical Spondylosis, Mulligan Mobilization, SNAGs, Muscle Energy Technique, Post Isometric Relaxation
- Keywords
- Mulligan Mobilization, Mobilization with Movement, SNAGs, Muscle Energy Technique, Post isometric relaxation, Cervical Spondylosis
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 40 participants (actual)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- 5 Nov 2024 (actual)
- Primary completion
- 1 Jan 2025 (actual)
- Study completion
- 1 Feb 2025 (actual)
- First posted
- 30 Oct 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will be aimed to answer the following questions:
Which technique, MET or MMT, is more effective in reducing pain, increasing range of motion (ROM), improving proprioception, and enhancing functional ability in individuals with CS?
It will be assumed that:
- All participants will adhere to study instructions and procedures.
- All participants will be evaluated under standardized conditions.
Detailed description
Cervical spondylosis (CS) is a highly prevalent age-related condition (95%), that affects the joints and discs of the cervical spine. By age 65, nearly all individuals experience some degree of degeneration, characterized by disc breakdown and enlarged facet joints. While aging is the primary cause, injuries can accelerate this process in younger populations.
Significance of the Study Age-related degenerative spinal changes are almost widespread. Population-based studies have shown that approximately 80 to 90% of people have disk degeneration on magnetic resonance imaging (MRI) by the age of 50 years.
A global burden review estimates that over 300 million people worldwide had mechanical neck pain lasting at least 3 months in 2015.
Clinical features of spondylosis are more common in men than in women, with a peak incidence between the ages of 40 and 60 years for both men and women.
Cervical spondylosis commonly affects the middle and lower cervical vertebrae (C5-C6 and C6-C7), although higher levels may also be involved. Neck pain is the most prominent symptom. CS can affect all cervical components (i.e., the spinal cord, spinal vasculature, and nerve roots). Cervical spondylosis Symptoms include cervical instability (abnormal movement or laxity between vertebrae). This instability can lead to various symptoms such as neck pain, muscle imbalance between cervical and shoulder girdle muscles (weakness in cervical flexors, lower trapezius, and anterior serratus; tightness in the upper trapezius, scapular lift, and pectoralis major), disc herniation and osteophyte formation. These can compromise proprioception (accurate sensory feedback) and limit neck mobility, significantly impacting function and daily activities.
Muscle energy techniques is a form of manual therapy frequently used by physical therapists to improve musculoskeletal function and alleviate pain. MET aims to adjust abnormal muscle tone by training specific muscles, enhancing strength and stability, improving the musculoskeletal function, and ultimately improving quality of life.
Another treatment technique is MMT that is now an integral component of many manual physiotherapists' clinical practice. MMT involves sustained passive accessory force/glide to a joint while the participant actively performs a problematic movement.
This study aims to address this gap in knowledge by investigating whether MET or MMT is more effective in improving pain, ROM, proprioception, and functional ability in individuals with cervical spondylosis. The findings from this study can provide valuable insights for physical therapists in selecting the most appropriate treatment approach for their patients with cervical spondylosis. By determining the more effective technique, physical therapists can optimize treatment plans and potentially improve patient outcomes.
This Triple-blinded (the examiner, statistician, and the participants will be blinded, while the therapist will be aware of treatment procedures) randomized controlled trial (RCT) will investigate the effectiveness of Muscle Energy Techniques (MET) compared to Mulligan Mobilization Techniques (MMT) on cervical spine pain, ROM, and function in participants with Cervical Spondylosis (CS). The study will be conducted at the outpatient physical therapy clinic of Horus University in New Damietta, Egypt.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (investigator, outcomes assessor)
- Number of arms
- 2
- Model description
- Model Description
| Arm | Type | Receives |
|---|---|---|
| Group (A) Muscle Energy Technique (MET). | Experimental | Other: Group (A) Muscle Energy Technique (MET)These participants will receive METs, in addition to a standard physical therapy program consisting of deep neck flexor strengthening exercises, isometric exercise, and range of motion exercises (3 sessions per week for 4 weeks). |
| Group (B) Mulligan Mobilization Technique group (MMT). | Experimental | Other: Group (B) Mulligan Mobilizations Techniques (MMT).Participants will receive MMT interventions alongside the standard physical therapy program deep neck flexor strengthening exercises, isometric exercise, and range of motion exercises 3 sessions per week for 4 weeks. |
Who may qualify
- Ages
- 40 to 60 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (7 listed)
- Participants of both genders aged 40 - 60 years old, diagnosed with clinically and medically stable CS.
- All participants will be assessed and referred by orthopedic surgeons before starting the study.
- Mechanical neck pain localized to the cervical.
- Neck pain lasting more than 3 months, local tenderness of the upper fibers of the trapezius, limitation in cervical ROM and muscle spasm.
- Moderate pain intensity (45-74 mm on VAS).
Key exclusion criteria (4 listed)
- Participants with systemic diseases like rheumatoid arthritis, metabolic diseases, or osteoporosis.
- History of trauma or accidental injuries to the cervical spine.
- Cervical myelopathy, inflammatory arthritis, tumors, infections involving the cervical spine, or vertebrobasilar artery insufficiency.
- Cervical spine injury, dizziness, vertigo, or any other musculoskeletal complaints.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Group (A) Muscle Energy Technique (MET)Also: Post Isometric RelaxationMET will be applied to three key muscles commonly associated with neck pain: upper trapezius, levator scapulae, and anterior scalenus. | Other | Group (A) Muscle Energy Technique (MET). |
| Group (B) Mulligan Mobilizations Techniques (MMT).Also: SNAGsParticipants in Group (B) will receive MMT alongside the traditional treatment. MMT utilizes a specific technique called Sustained Natural Apophyseal Glides (SNAGs) to improve joint mobilization. | Other | Group (B) Mulligan Mobilization Technique group (MMT). |
Primary outcome
Cervical Range of Motion (CROM)
Time frame: Pre- intervention and after 4 weeks of treatment
to measure the Cervical ROM for (Flexion, Extension, Rotation for both sides and Sidebending for both sides) and proprioception (Neutral head position test, and Target head position)
The Arabic Version Of Neck Disability Index (NDI).
Time frame: Pre- intervention and after 4 weeks of treatment
to assess the level of disabilities in patients with neck pain, in % points
Visual Analogue Scale (VAS).
Time frame: Pre- intervention and after 4 weeks of treatment
to measure neck pain with score extended from 0 to 10, minimum score 0 (no pain), highest score 10 (worst pain).
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Jul 2025.
- Background: PubMed 26695177Binch AL, Cole AA, Breakwell LM, Michael AL, Chiverton N, Creemers LB, Cross AK, Le Maitre CL. Nerves are more abundant than blood vessels in the degenerate human intervertebral disc. Arthritis Res Ther. 2015 Dec 21;17:370. doi: 10.1186/s13075-015-0889-6.
- Background: PubMed 34111066Manzoor A, Anwar N, Khalid K, Haider R, Saghir M, Javed MA. Comparison of effectiveness of muscle energy technique with Mulligan mobilization in patients with non-specific neck pain. J Pak Med Assoc. 2021 Jun;71(6):1532-1524. doi: 10.47391/JPMA.981.
- Background: PubMed 33907460Atisook R, Euasobhon P, Saengsanon A, Jensen MP. Validity and Utility of Four Pain Intensity Measures for Use in International Research. J Pain Res. 2021 Apr 21;14:1129-1139. doi: 10.2147/JPR.S303305. eCollection 2021.
- Background: PubMed 20436238Audette I, Dumas JP, Cote JN, De Serres SJ. Validity and between-day reliability of the cervical range of motion (CROM) device. J Orthop Sports Phys Ther. 2010 May;40(5):318-23. doi: 10.2519/jospt.2010.3180.
- Background: PubMed 36120766Bagcaci S, Unuvar BS, Gercek H, Ugurlu I, Sert OA, Yilmaz K. A randomized controlled trial on pain, grip strength, and functionality in lateral elbow pain: Mulligan vs muscle energy techniques. J Back Musculoskelet Rehabil. 2023;36(2):419-427. doi: 10.3233/BMR-220061.
- Background: PubMed 28894688Bakhsheshian J, Mehta VA, Liu JC. Current Diagnosis and Management of Cervical Spondylotic Myelopathy. Global Spine J. 2017 Sep;7(6):572-586. doi: 10.1177/2192568217699208. Epub 2017 May 31.
- Background: PubMed 17204884Baron EM, Young WF. Cervical spondylotic myelopathy: a brief review of its pathophysiology, clinical course, and diagnosis. Neurosurgery. 2007 Jan;60(1 Supp1 1):S35-41. doi: 10.1227/01.NEU.0000215383.64386.82.
- Background: PubMed 17347239Binder AI. Cervical spondylosis and neck pain. BMJ. 2007 Mar 10;334(7592):527-31. doi: 10.1136/bmj.39127.608299.80. No abstract available.
- Background: PubMed 21168100Bono CM, Ghiselli G, Gilbert TJ, Kreiner DS, Reitman C, Summers JT, Baisden JL, Easa J, Fernand R, Lamer T, Matz PG, Mazanec DJ, Resnick DK, Shaffer WO, Sharma AK, Timmons RB, Toton JF; North American Spine Society. An evidence-based clinical guideline for the diagnosis and treatment of cervical radiculopathy from degenerative disorders. Spine J. 2011 Jan;11(1):64-72. doi: 10.1016/j.spinee.2010.10.023.
- Background: PubMed 25430861Brinjikji W, Luetmer PH, Comstock B, Bresnahan BW, Chen LE, Deyo RA, Halabi S, Turner JA, Avins AL, James K, Wald JT, Kallmes DF, Jarvik JG. Systematic literature review of imaging features of spinal degeneration in asymptomatic populations. AJNR Am J Neuroradiol. 2015 Apr;36(4):811-6. doi: 10.3174/ajnr.A4173. Epub 2014 Nov 27.
- Background: PubMed 29861800Buyukturan O, Buyukturan B, Sas S, Kararti C, Ceylan I. The Effect of Mulligan Mobilization Technique in Older Adults with Neck Pain: A Randomized Controlled, Double-Blind Study. Pain Res Manag. 2018 May 15;2018:2856375. doi: 10.1155/2018/2856375. eCollection 2018.
- Background: PubMed 24133553Cheung J, Kajaks T, Macdermid JC. The relationship between neck pain and physical activity. Open Orthop J. 2013 Sep 20;7:521-9. doi: 10.2174/1874325001307010521. eCollection 2013.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Group (A) Muscle Energy Technique (MET) and Group (B) Mulligan Mobilizations Techniques (MMT). in people with Cervical Spondylosis and Mulligan Mobilization, run by Cairo University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 7 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 16 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Cervical Range of Motion (CROM) (time frame: Pre- intervention and after 4 weeks of treatment). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06664931, which also lists 57 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Jul 2025.