Obesity and OverweightNCT06670703
A Clinical Study of the Effects of Environmental Pollution on Obesity
An observational study of Obesity and Overweight, run by Dong Peng at 3 sites in China.
Trial summary
This study aims to assess the effects of environmental pollution (including environmental indicators such as PM2.5, PM5, PM10, SO2, NOX, O3, and greening index) on obese patients and to explore the possible mechanisms by which environmental pollution promotes obesity. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Obesity and Overweight
- What is being tested?
- Obesity
- How many people
- 800 participants
- Where
- 3 sitesChina
- Study dates
- 1 Jan 2011to 30 Oct 2024
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: This is a retrospective observational study, which is expected to include patients diagnosed with obesity ( body mass index (BMI) ≥ 28 kg/m2).
Who may be able to join
- Age ≥18 years;
- obese patients with BMI ≥30;
- patients without surgical treatment prior to enrolment;
- willingness to participate in the study and sign an informed consent form;
- complete clinical data.
Who cannot join
- patients with systemic diseases such as severe cardiorespiratory insufficiency affecting the choice of treatment regimen;
- patients assessed by the investigator to be inappropriate for enrolment;
- patients with incomplete clinical data.
Trial locations and contacts
3 sites in 1 country.
China3 sites
The First Affiliated Hospital of Chongqing Medical University
Chongqing, Chongqing Municipality, 400016
Affiliated Hospital of Yunnan University
Kunming, Yunnan, 650000
The Second People's Hospital of Qujing
Kunming, Yunnan, 650000
About this study
This study aims to assess the effects of environmental pollution (including environmental indicators such as PM2.5, PM5, PM10, SO2, NOX, O3, and greening index) on obese patients and to explore the possible mechanisms by which environmental pollution promotes obesity.
Read the detailed description
Firstly, the effects of environmental pollution on obese patients were investigated by analysing the baseline conditions and obesity levels (including BMI, waist circumference, hip circumference, etc.) and underlying diseases of obese patients in regions with different pollution levels. Secondly, the association between environmental pollution levels on blood test characteristics (including renal function, sex hormones, glucose tolerance test, trace elements, liver function and blood routine) of obese patients was investigated to find possible mechanisms.
- Conditions
- Obesity and Overweight
- Being tested
- Obesity
- Keywords
- air pollution, obesity, prevalence, overweight, environment
- Medical subject headings
- Obesity, Overweight
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ObesityDiagnostic test
diagnosis as obese patients
| Study group | Role | What they receive |
|---|---|---|
| the obesity group | Obese patients attending the First Affiliated Hospital of Chongqing Medical University, the Affiliated Hospital of Yunnan University, and the Second People's Hospital of Qujing City. Receives: Diagnostic Test: Obesity |
What is being measured
The primary outcome is the main question the study is designed to answer.
incidence of obesity
the time for overweight to obesity
Measured: From 18 years old until the developing obesity, through study completion, an average of 5 year.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Nov 2024
- Study start1 Jan 2011
- Primary completion30 Oct 2024 (estimated)
- Study completion30 Oct 2024 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Obesity and OverweightStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 800 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Dong Peng
- Sponsor type
- University, hospital or other
- Collaborators
- Affiliated Hospital of Yunnan University, The Second People's Hospital of Qujing
- Responsible party
- Sponsor-investigator, Dong Peng, First Affiliated Hospital of Chongqing Medical University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06670703
- Sponsor's protocol ID
- ZZ2024-350-02
- Status last verified
- Oct 2024
- First submitted
- 31 Oct 2024
- Last updated
- 1 Nov 2024
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Ethics committees of the clinical centres where the studies were conducted did not allow the release of patient data.
Study at a glance
From the registry record, last updated by the sponsor on 1 Nov 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- A Clinical Study of the Effects of Environmental Pollution on Obesity
- ClinicalTrials.gov ID
- NCT06670703
- Acronym / sponsor ID
- ZZ2024-350-02
- Conditions
- Obesity and Overweight
- Keywords
- air pollution, obesity, prevalence, overweight, environment
- Study type
- Observational
- Recruitment status
- Unknown status
- Enrolment
- 800 participants (estimated)
- Lead sponsor
- Dong PengUniversity, hospital or other
- Collaborators
- Affiliated Hospital of Yunnan University, The Second People's Hospital of Qujing
- Study start
- 1 Jan 2011 (actual)
- Primary completion
- 30 Oct 2024 (estimated)
- Study completion
- 30 Oct 2024 (estimated)
- First posted
- 1 Nov 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to assess the effects of environmental pollution (including environmental indicators such as PM2.5, PM5, PM10, SO2, NOX, O3, and greening index) on obese patients and to explore the possible mechanisms by which environmental pollution promotes obesity.
Detailed description
Firstly, the effects of environmental pollution on obese patients were investigated by analysing the baseline conditions and obesity levels (including BMI, waist circumference, hip circumference, etc.) and underlying diseases of obese patients in regions with different pollution levels. Secondly, the association between environmental pollution levels on blood test characteristics (including renal function, sex hormones, glucose tolerance test, trace elements, liver function and blood routine) of obese patients was investigated to find possible mechanisms.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| the obesity group | – | Diagnostic Test: ObesityObese patients attending the First Affiliated Hospital of Chongqing Medical University, the Affiliated Hospital of Yunnan University, and the Second People's Hospital of Qujing City. |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- This is a retrospective observational study, which is expected to include patients diagnosed with obesity ( body mass index (BMI) ≥ 28 kg/m2).
Key inclusion criteria (5 listed)
- Age ≥18 years;
- obese patients with BMI ≥30;
- patients without surgical treatment prior to enrolment;
- willingness to participate in the study and sign an informed consent form;
- complete clinical data.
Key exclusion criteria (3 listed)
- patients with systemic diseases such as severe cardiorespiratory insufficiency affecting the choice of treatment regimen;
- patients assessed by the investigator to be inappropriate for enrolment;
- patients with incomplete clinical data.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Obesitydiagnosis as obese patients | Diagnostic test | the obesity group |
Primary outcome
incidence of obesity
Time frame: From 18 years old until the developing obesity, through study completion, an average of 5 year.
the time for overweight to obesity
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 1 Nov 2024.
- Individual participant dataSharing planned: No. Ethics committees of the clinical centres where the studies were conducted did not allow the release of patient data.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
3 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Obesity and Overweight, run by Dong Peng at 3 sites in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 1 Nov 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 3 sites in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
incidence of obesity (time frame: From 18 years old until the developing obesity, through study completion, an average of 5 year.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 1 Nov 2024.