Thoracic Aorta DilatationNCT06684496
A Study of High-intensity Strength Training and Thoracic Aorta Dilatation
An observational study of Thoracic Aorta Dilatation, run by Mayo Clinic at 1 site in United States.
Trial summary
The purpose of this study is to describe the prevalence of thoracic aorta dilatation among a group of older (age > 35 years), experienced weightlifters (>5 years of weightlifting experience). Read more about this study
- Who is it for?
- Ages 35 years and olderHealthy volunteers can take part
- Conditions the study is for
- Thoracic Aorta Dilatation
- How many people
- 45 participants
- Where
- 1 siteUnited States
- Study dates
- 23 Dec 2024to Nov 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 35 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: The target population is power lifters (n=15), body builders (n=15), and cross-fit (n=15) athletes age 35 years or older with at least 5 years of consistent weight training
Who may be able to join
- Age ≥ 35
- ≥5 years of weightlifting experience
Who cannot join
- Age < 35
- < 5 years of weightlifting experience
- personal history of thoracic aorta dilatation/aneurysm/dissection
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Strength Training and Thoracic Aorta Dilatation: an Echocardiographic Cross-sectional Study
The purpose of this study is to describe the prevalence of thoracic aorta dilatation among a group of older (age > 35 years), experienced weightlifters (>5 years of weightlifting experience). The secondary aim of this study is to report the prevalence of thoracic aorta dilatation among 3 different groups of weightlifters (body builders, cross-fit athletes, and power lifters).
- Conditions
- Thoracic Aorta Dilatation
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of subjects with thoracic aorta dilatation
Thoracic aorta dilatation will be measured by TTE (Transthoracic echocardiogram). A value over 40 mm indicates thoracic aorta dilatation.
Measured: Baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Nov 2024
- Study start23 Dec 2024
- Primary completionNov 2026 (estimated)
- Study completionNov 2026 (estimated)
Why it stopped: Pending additional funding
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Thoracic Aorta DilatationStudies of the same condition, open and under way.
- More trials run by Mayo ClinicThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 45 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Mayo Clinic
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Darrell B. Newman, Mayo Clinic
- Investigators
- Darrell Newman, M.D., Principal investigator, Mayo Clinic
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06684496
- Sponsor's protocol ID
- 24-007099
- Status last verified
- Mar 2026
- First submitted
- 10 Nov 2024
- Last updated
- 12 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 12 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Strength Training and Thoracic Aorta Dilatation: an Echocardiographic Cross-sectional Study
- ClinicalTrials.gov ID
- NCT06684496
- Acronym / sponsor ID
- 24-007099
- Conditions
- Thoracic Aorta Dilatation
- Study type
- Observational
- Recruitment status
- SuspendedReason stopped: Pending additional funding
- Enrolment
- 45 participants (estimated)
- Lead sponsor
- Mayo ClinicUniversity, hospital or other
- Study start
- 23 Dec 2024 (actual)
- Primary completion
- Nov 2026 (estimated)
- Study completion
- Nov 2026 (estimated)
- First posted
- 12 Nov 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study is to describe the prevalence of thoracic aorta dilatation among a group of older (age > 35 years), experienced weightlifters (>5 years of weightlifting experience). The secondary aim of this study is to report the prevalence of thoracic aorta dilatation among 3 different groups of weightlifters (body builders, cross-fit athletes, and power lifters).
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 35 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- The target population is power lifters (n=15), body builders (n=15), and cross-fit (n=15) athletes age 35 years or older with at least 5 years of consistent weight training
Key inclusion criteria (2 listed)
- Age ≥ 35
- ≥5 years of weightlifting experience
Key exclusion criteria (3 listed)
- Age < 35
- < 5 years of weightlifting experience
- personal history of thoracic aorta dilatation/aneurysm/dissection
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Number of subjects with thoracic aorta dilatation
Time frame: Baseline
Thoracic aorta dilatation will be measured by TTE (Transthoracic echocardiogram). A value over 40 mm indicates thoracic aorta dilatation.
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 12 Mar 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Darrell Newman, M.D. principal investigator
Mayo Clinic
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Thoracic Aorta Dilatation, run by Mayo Clinic at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: paused, as of the sponsor's last update on 12 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of subjects with thoracic aorta dilatation (time frame: Baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 12 Mar 2026.