StrokeNCT06688812
Comparing Perceptual Motor Training and Repetitive Facilitation Exercises on UE in Stroke
A study testing Perceptual Motor Training and Repetitive Facilitation Exercises in people with Stroke, run by Riphah International University at 1 site in Pakistan.
Trial summary
The aim of the study is to determine the comparative effects of perceptual motor training and repetitive facilitation exercises on upper limb quality of movement and motor function in Stroke patients. Read more about this study
- Who is it for?
- Ages 40 to 65 years
- Conditions the study is for
- Stroke
- What is being tested?
- Perceptual Motor Training and Repetitive Facilitation Exercises
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 sitePakistan
- Study dates
- 25 Nov 2024to 30 Jul 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Both male and female patients.
- Age 40-65 years
- 1st ever stroke confirmed by MRI
- mild-to-moderate upper-limb motor paralysis
- sub-acute and chronic stroke patients
- ability to understand tasks such as evaluations in the intervention
- Modified Ashworth scale score < 3
- Mini Mental State Examination Score should be>24 out of 30
Who cannot join
- Participants who have a history of significant neurological or psychiatric disorders, other than stroke, that could interfere with upper limb motor recovery
- Patients with pain, contracture and profound atrophy in arm and fingers.
- Participants with severe cognitive dysfunction that would interfere with understanding instructions from the physician or therapist.
- Presence of any other musculoskeletal condition. e.g. (Frozen shoulder, any recent fractures of upper limb.
- Any accompanying diseases or disorders, other than stroke, that could interfere with upper extremity training.
- Uncontrolled health conditions for which exercise was contraindicated.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site
Dr. Faisal Masood Teaching Hospital
Sargodha, Punjab Province, 40100
Hira Jabeen, MS-NMPT, 03234116506, hira.jabeen@riphah.edu.pk
Hafiza Ayema Mufti, DPT
About this study
Official title: Comparative Effects of Perceptual Motor Training and Repetitive Facilitation Exercises on Upper Limb Quality of Movement and Motor Function in Stroke Patients
The aim of the study is to determine the comparative effects of perceptual motor training and repetitive facilitation exercises on upper limb quality of movement and motor function in Stroke patients.
Read the detailed description
Perceptual-motor training enhances proprioception, spatial awareness, and coordination through object manipulation. On the other hand, Repetitive facilitation exercises aim to improve motor control and reduce spasticity by stimulating muscles repetitively. Decreased dexterity, coordination, muscle tone abnormalities, and diminished sensation are frequently observed in stroke patients. Effective rehabilitation in daily tasks depends on coordinated efforts among muscles, joints, and body segments, influenced by environmental factors and personal constraints. Visual input, perception, and cognitive processing play crucial roles in action planning during rehabilitation.
This is a randomized clinical trial. The data will be collected from DHQ hospital, Sargodha. 50 stroke patients will be included using convenience sampling. The participants who meet the inclusion criteria will be randomly allocated into two groups. Twenty-five participants will be included in both Groups A and B. Group A (perceptual motor training with routine physical therapy) and Group B (Repetitive facilitation exercises with routine physical therapy) will receive 60 minutes treatment session that consists of 40 minutes of intervention and 20 minutes of routine physical therapy four sessions per week for 8 weeks.
Quality of movement will be assessed using Motor Evaluation Scale for Upper Extremity in Stroke Patients (MESUPES) and motor function by Fugl-Meyer Assessment (FMA-UE) Assessments will occur at baseline, 4 weeks, and 8 weeks. Data analysis will utilize SPSS version 27 for Windows, with statistical significance set at p ≤ 0.05.
- Conditions
- Stroke
- Being tested
- Perceptual Motor Training, Repetitive Facilitation Exercises
- Keywords
- exercise, motor skills, rehabilitation, stroke, upper extremity
- Medical subject headings
- Stroke, Motor Activity
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Perceptual Motor TrainingOther
8 set of exercises
- Balance training and related exercises
- Tones of awareness training, body parts' role and related exercises
- Space awareness training and related exercises
- Perception of shape training and related exercises
- Visual perception training and related exercise.
- Kinesthetic-tactile perception training and related exercises
- Auditory perception training and related exercises
- Eye and hand coordination, fine motor movements and related Exercises
Repetitive Facilitation ExercisesOther
Eight set of exercises:
- Shoulder Flexion with 90° Elbow Flexion (Supine).
- Shoulder Horizontal Extension/Flexion with Elbow flexion (supine).
- Complex Shoulder and Upper Limb Movements (Supine)
- Shoulder Flexion/Abduction/External Rotation with Elbow and Forearm Supination (Supine)
- Forearm Supination/Pronation with 90° Elbow Flexion (Sitting)
- Wrist Extension and Forearm Pronation with Finger Extension (Supine)
- Finger Extension with Wrist Flexion (Supine)
- Finger Extension/Flexion with Wrist Flexion (Sitting) • Therapist facilitate the movement by rubbing, tapping and gentle stretching.
| Study group | Role | What they receive |
|---|---|---|
| Group A Perceptual Motor Training with Routine Physical Therapy | Experimental | Group A will receive treatment session of 60 minutes including Perceptual motor training for 40 minutes along with routine physical therapy of 20 minutes. Treatment session will be given 4 days per week for 8 weeks. Effects will be measured at baseline, 4th week and post intervention. Receives: Other: Perceptual Motor Training |
| Group B Repetitive Facilitation Exercises with Routine Physical Therapy | Experimental | Group B will receive treatment session of 60 minutes including Repetitive facilitation exercises for 40 minutes along with routine physical therapy of 20 minutes. Treatment session will be given 4 days per week for 8 weeks. Effects will be measured at baseline, 4th week and post intervention. Receives: Other: Repetitive Facilitation Exercises |
What is being measured
The primary outcome is the main question the study is designed to answer.
1. Motor Evaluation Scale For Upper Extremity In Stroke Patients (MESUPES)
A 17-items into two sub scales ; MESUPES Arm function; 8 items(score 0-5) MESUPES-Hand function; 9 items (score0-2) objective evaluation scale designed to assess quality of movement of arm and hand function after stroke. MESUPES takes 5-15 min to complete. Total score 58. A higher score indicates the greater the quality of movement
Measured: 8 week
2. Fugl-Meyer Assessment (FMA):
The Fugl-Meyer Assessment is used to assess motor function. It is a well-designed, feasible and efficient clinical examination method that has been tested widely in the stroke population. A three-level ordinal scale (0, can perform no part of the test; 1, performs test partially; 2, performs test normally) is applied to each item. A total possible score for the upper extremity is 66. The higher the score, the better the performance.
Measured: 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted14 Nov 2024
- Study start25 Nov 2024 (estimated)
- Primary completion30 Jul 2025 (estimated)
- Study completion30 Jul 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (7)Papers the sponsor has linked to this study.
- Other trials for StrokeStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Hira Jabeen, MS-NMPT, Study chair, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06688812
- Sponsor's protocol ID
- REC/RCR & AHS/24/0253
- Status last verified
- Nov 2024
- First submitted
- 12 Nov 2024
- Last updated
- 14 Nov 2024
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
McGregor HR, Cashaback JGA, Gribble PL. Somatosensory perceptual training enhances motor learning by observing. J Neurophysiol. 2018 Dec 1;120(6):3017-3025. doi: 10.1152/jn.00313.2018. Epub 2018 Sep 19.
PubMed 30230990Soltani Kouhbanani S, Arabi SM, Zarenezhad S, Khosrorad R. The Effect of Perceptual-Motor Training on Executive Functions in Children with Non-Verbal Learning Disorder. Neuropsychiatr Dis Treat. 2020 May 5;16:1129-1137. doi: 10.2147/NDT.S252662. eCollection 2020.
PubMed 32440127Bergmann F, Gray R, Wachsmuth S, Honer O. Perceptual-Motor and Perceptual-Cognitive Skill Acquisition in Soccer: A Systematic Review on the Influence of Practice Design and Coaching Behavior. Front Psychol. 2021 Dec 2;12:772201. doi: 10.3389/fpsyg.2021.772201. eCollection 2021.
PubMed 34925173Platzer WS. Effect of perceptual motor training on gross-motor skill and self-concept of young children. Am J Occup Ther. 1976 Aug;30(7):422-8.
PubMed 941962Fujimoto K, Ueno M, Etoh S, Shimodozono M. Combined repetitive facilitative exercise under continuous neuromuscular electrical stimulation and task-oriented training for hemiplegic upper extremity during convalescent phase after stroke: before-and-after feasibility trial. Front Neurol. 2024 Feb 22;15:1356732. doi: 10.3389/fneur.2024.1356732. eCollection 2024.
PubMed 38456153Purton J, Sim J, Hunter SM. Stroke survivors' views on their priorities for upper-limb recovery and the availability of therapy services after stroke: a longitudinal, phenomenological study. Disabil Rehabil. 2023 Sep;45(19):3059-3069. doi: 10.1080/09638288.2022.2120097. Epub 2022 Sep 15.
PubMed 36111388Hokazono A, Etoh S, Jonoshita Y, Kawahira K, Shimodozono M. Combination therapy with repetitive facilitative exercise program and botulinum toxin type A to improve motor function for the upper-limb spastic paresis in chronic stroke: A randomized controlled trial. J Hand Ther. 2022 Oct-Dec;35(4):507-515. doi: 10.1016/j.jht.2021.01.005. Epub 2021 Jan 26.
PubMed 33820711
Study at a glance
From the registry record, last updated by the sponsor on 14 Nov 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Effects of Perceptual Motor Training and Repetitive Facilitation Exercises on Upper Limb Quality of Movement and Motor Function in Stroke Patients
- ClinicalTrials.gov ID
- NCT06688812
- Acronym / sponsor ID
- REC/RCR & AHS/24/0253
- Conditions
- Stroke
- Keywords
- exercise, motor skills, rehabilitation, stroke, upper extremity
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 25 Nov 2024 (estimated)
- Primary completion
- 30 Jul 2025 (estimated)
- Study completion
- 30 Jul 2025 (estimated)
- First posted
- 14 Nov 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The aim of the study is to determine the comparative effects of perceptual motor training and repetitive facilitation exercises on upper limb quality of movement and motor function in Stroke patients.
Detailed description
Perceptual-motor training enhances proprioception, spatial awareness, and coordination through object manipulation. On the other hand, Repetitive facilitation exercises aim to improve motor control and reduce spasticity by stimulating muscles repetitively. Decreased dexterity, coordination, muscle tone abnormalities, and diminished sensation are frequently observed in stroke patients. Effective rehabilitation in daily tasks depends on coordinated efforts among muscles, joints, and body segments, influenced by environmental factors and personal constraints. Visual input, perception, and cognitive processing play crucial roles in action planning during rehabilitation.
This is a randomized clinical trial. The data will be collected from DHQ hospital, Sargodha. 50 stroke patients will be included using convenience sampling. The participants who meet the inclusion criteria will be randomly allocated into two groups. Twenty-five participants will be included in both Groups A and B. Group A (perceptual motor training with routine physical therapy) and Group B (Repetitive facilitation exercises with routine physical therapy) will receive 60 minutes treatment session that consists of 40 minutes of intervention and 20 minutes of routine physical therapy four sessions per week for 8 weeks.
Quality of movement will be assessed using Motor Evaluation Scale for Upper Extremity in Stroke Patients (MESUPES) and motor function by Fugl-Meyer Assessment (FMA-UE) Assessments will occur at baseline, 4 weeks, and 8 weeks. Data analysis will utilize SPSS version 27 for Windows, with statistical significance set at p ≤ 0.05.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group A Perceptual Motor Training with Routine Physical Therapy | Experimental | Other: Perceptual Motor TrainingGroup A will receive treatment session of 60 minutes including Perceptual motor training for 40 minutes along with routine physical therapy of 20 minutes. Treatment session will be given 4 days per week for 8 weeks. Effects will be measured at baseline, 4th week and post intervention. |
| Group B Repetitive Facilitation Exercises with Routine Physical Therapy | Experimental | Other: Repetitive Facilitation ExercisesGroup B will receive treatment session of 60 minutes including Repetitive facilitation exercises for 40 minutes along with routine physical therapy of 20 minutes. Treatment session will be given 4 days per week for 8 weeks. Effects will be measured at baseline, 4th week and post intervention. |
Who may qualify
- Ages
- 40 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (8 listed)
- Both male and female patients.
- Age 40-65 years
- 1st ever stroke confirmed by MRI
- mild-to-moderate upper-limb motor paralysis
- sub-acute and chronic stroke patients
Key exclusion criteria (6 listed)
- Participants who have a history of significant neurological or psychiatric disorders, other than stroke, that could interfere with upper limb motor recovery
- Patients with pain, contracture and profound atrophy in arm and fingers.
- Participants with severe cognitive dysfunction that would interfere with understanding instructions from the physician or therapist.
- Presence of any other musculoskeletal condition. e.g. (Frozen shoulder, any recent fractures of upper limb.
- Any accompanying diseases or disorders, other than stroke, that could interfere with upper extremity training.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Perceptual Motor Training8 set of exercises 1. Balance training and related exercises 2. Tones of awareness training, body parts' role and related exercises 3. Space awareness training and related exercises 4. Perception of shape training and related exercises 5. Visual perception training and related exercise. 6. Kinesthetic-tactile perception training and related exercises 7. Auditory perception training and related exercises 8. Eye and hand coordination, fine motor movements and related Exercises | Other | Group A Perceptual Motor Training with Routine Physical Therapy |
| Repetitive Facilitation ExercisesEight set of exercises: 1. Shoulder Flexion with 90° Elbow Flexion (Supine). 2. Shoulder Horizontal Extension/Flexion with Elbow flexion (supine). 3. Complex Shoulder and Upper Limb Movements (Supine) 4. Shoulder Flexion/Abduction/External Rotation with Elbow and Forearm Supination (Supine) 5. Forearm Supination/Pronation with 90° Elbow Flexion (Sitting) 6. Wrist Extension and Forearm Pronation with Finger Extension (Supine) 7. Finger Extension with Wrist Flexion (Supine) 8. Finger Extension/Flexion with Wrist Flexion (Sitting) • Therapist facilitate the movement by rubbing, tapping and gentle stretching. | Other | Group B Repetitive Facilitation Exercises with Routine Physical Therapy |
Primary outcome
1. Motor Evaluation Scale For Upper Extremity In Stroke Patients (MESUPES)
Time frame: 8 week
A 17-items into two sub scales ; MESUPES Arm function; 8 items(score 0-5) MESUPES-Hand function; 9 items (score0-2) objective evaluation scale designed to assess quality of movement of arm and hand function after stroke. MESUPES takes 5-15 min to complete. Total score 58. A higher score indicates the greater the quality of movement
2. Fugl-Meyer Assessment (FMA):
Time frame: 8 weeks
The Fugl-Meyer Assessment is used to assess motor function. It is a well-designed, feasible and efficient clinical examination method that has been tested widely in the stroke population. A three-level ordinal scale (0, can perform no part of the test; 1, performs test partially; 2, performs test normally) is applied to each item. A total possible score for the upper extremity is 66. The higher the score, the better the performance.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Nov 2024.
- Background: PubMed 30230990McGregor HR, Cashaback JGA, Gribble PL. Somatosensory perceptual training enhances motor learning by observing. J Neurophysiol. 2018 Dec 1;120(6):3017-3025. doi: 10.1152/jn.00313.2018. Epub 2018 Sep 19.
- Background: PubMed 32440127Soltani Kouhbanani S, Arabi SM, Zarenezhad S, Khosrorad R. The Effect of Perceptual-Motor Training on Executive Functions in Children with Non-Verbal Learning Disorder. Neuropsychiatr Dis Treat. 2020 May 5;16:1129-1137. doi: 10.2147/NDT.S252662. eCollection 2020.
- Background: PubMed 34925173Bergmann F, Gray R, Wachsmuth S, Honer O. Perceptual-Motor and Perceptual-Cognitive Skill Acquisition in Soccer: A Systematic Review on the Influence of Practice Design and Coaching Behavior. Front Psychol. 2021 Dec 2;12:772201. doi: 10.3389/fpsyg.2021.772201. eCollection 2021.
- Background: PubMed 941962Platzer WS. Effect of perceptual motor training on gross-motor skill and self-concept of young children. Am J Occup Ther. 1976 Aug;30(7):422-8.
- Background: PubMed 38456153Fujimoto K, Ueno M, Etoh S, Shimodozono M. Combined repetitive facilitative exercise under continuous neuromuscular electrical stimulation and task-oriented training for hemiplegic upper extremity during convalescent phase after stroke: before-and-after feasibility trial. Front Neurol. 2024 Feb 22;15:1356732. doi: 10.3389/fneur.2024.1356732. eCollection 2024.
- Background: PubMed 36111388Purton J, Sim J, Hunter SM. Stroke survivors' views on their priorities for upper-limb recovery and the availability of therapy services after stroke: a longitudinal, phenomenological study. Disabil Rehabil. 2023 Sep;45(19):3059-3069. doi: 10.1080/09638288.2022.2120097. Epub 2022 Sep 15.
- Background: PubMed 33820711Hokazono A, Etoh S, Jonoshita Y, Kawahira K, Shimodozono M. Combination therapy with repetitive facilitative exercise program and botulinum toxin type A to improve motor function for the upper-limb spastic paresis in chronic stroke: A randomized controlled trial. J Hand Ther. 2022 Oct-Dec;35(4):507-515. doi: 10.1016/j.jht.2021.01.005. Epub 2021 Jan 26.
- Individual participant dataSharing planned: No
Related trials for Stroke
Not yet recruiting
Temporal Interference Stimulation for Upper-Limb Motor Recovery in Early Subacute Stroke
Acute Ischemic Stroke
RecruitingObservational study
ELATE Study: Evaluating Large-vessel Acute Thrombectomy in Extended Time Window
Acute Ichemic Stroke
Recruiting
Web-Based Tele-Rehabilitation Using Action Observation and Mirror Therapy for Subacute Stroke: A Randomized Controlled Trial
Stroke, Upper Extremity Paresis
Recruiting
Early Motor-Cognitive Integrative Training on Cognitive and Motor Performance in Patients With Aneurysmal Subarachnoid Hemorrhage
Subarachnoid Aneurysm Hemorrhage
Not yet recruiting
Selective Intra-Arterial Hypothermia After Endovascular Treatment for Acute Basilar Artery Occlusion
Acute Ischemic Stroke, Basilar Artery Occlusion
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Hira Jabeen, MS-NMPT study chair
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Perceptual Motor Training and Repetitive Facilitation Exercises in people with Stroke, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 14 Nov 2024. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Hira Jabeen, MS-NMPT (03234116506, hira.jabeen@riphah.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
1. Motor Evaluation Scale For Upper Extremity In Stroke Patients (MESUPES) (time frame: 8 week). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06688812, which also lists 7 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Nov 2024.