Rheumatoid Arthritis (RANCT06691997
The Impact of Glycemic Control on Rheumatoid Arthritis Disease Activity on Diabetic Patients
An observational study of Rheumatoid Arthritis (RA and Diabetes Mellitus, run by Assiut University at 1 site in Egypt.
Trial summary
The incidence of DM is unclear in RA but most prior data suggest that DM or insulin resistance in RA has risen because of activation of the immune system and/or RA therapy . Besides, RA causes joints to become stiff, swollen, and agonizing. As a result, the patient may not want to exercise or move. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Rheumatoid Arthritis (RA, Diabetes Mellitus
- How many people
- 100 participants
- Where
- 1 siteEgypt
- Study dates
- 12 Dec 2024to 1 Jun 2027
- Phase
- Observational
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: Patients above age of 18 years old diagnosed with Rheumatoid Arthritis and DM
Who may be able to join
- type 2 diabetic patients
- rheumatoid arthritis patients
Who cannot join
- gestional diabetes
- type 1 diabetic patients
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
About this study
Official title: The Impact of Glycemic Control on Rheumatoid Arthritis Disease Activity in Diabetic Patients
The incidence of DM is unclear in RA but most prior data suggest that DM or insulin resistance in RA has risen because of activation of the immune system and/or RA therapy .
Besides, RA causes joints to become stiff, swollen, and agonizing. As a result, the patient may not want to exercise or move. One study found that 42% of people with RA are not physically active. the aim of this study is To evaluate the glycemic status among RA patients with Type 2 diabetes and its association with disease activity.
Read the detailed description
Taking the potential link between DM and RA into consideration, detection and control of DM will significantly increase prolonged prognosis and therefore decrease the economic burden of RA patients and death rate. The aim of this research is to examine diabetic RA's glycemic status and to assess the relationship between RA and DM's clinical characteristics as well as the therapy response in RA patients with diagnosed DM. Keeping an eye on glycemic control in RA patients could prevent metabolic and cardiovascular comorbidities in those susceptible patients.
- Conditions
- Rheumatoid Arthritis (RA, Diabetes Mellitus
- Keywords
- glycemic control
- Medical subject headings
- Arthritis, Rheumatoid, Diabetes Mellitus
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| group 1 | RA patients with Type 2 diabetes |
What is being measured
The primary outcome is the main question the study is designed to answer.
Fasting blood glucose
correlation between type 2 diabetes control and rheumatoid arthritis activity
Measured: baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Nov 2024
- Study start12 Dec 2024 (estimated)
- Primary completion14 Nov 2026 (estimated)
- Study completion1 Jun 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Rheumatoid Arthritis (RAStudies of the same condition, open and under way.
- More trials run by Assiut UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case only
- Time perspective
- Cross-sectional
- Enrolment
- 100 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Assiut University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmed Khedr Nady Abd Elaziz, Assiut University
- Investigators
- Ahmed khedr Nady, Principal investigator, Assiut University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06691997
- Sponsor's protocol ID
- DM and Rheumatoid Arthritis
- Status last verified
- Nov 2024
- First submitted
- 27 Oct 2024
- Last updated
- 18 Nov 2024
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided: According to result of search