Difficult AirwayNCT06700265
Ultrasound Airway Examination as a Tool for Detection of Difficult Intubation in Adult Patients
An observational study of Difficult Airway, run by National Cancer Institute, Egypt at 1 site in Egypt.
Trial summary
the goal of the observational study to measure the effectiveness of neck ultrasound in prediction of difficult intubation in adult patients Read more about this study
- Who is it for?
- Ages 18 to 70 yearsHealthy volunteers can take part
- Conditions the study is for
- Difficult Airway
- How many people
- 246 participants
- Where
- 1 siteEgypt
- Study dates
- 20 Mar 2023to 1 Mar 2026
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 70 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: all population undergoining surgical operation requiring general anesthesia and endotracheal intubation
Who may be able to join
- Adult patients above18 years old
- Both sex
- Requiring general anesthesia with endotracheal intubation
Who cannot join
- Emergency surgery,
- patients with limited mouth, head or neck movement,
- patients with temporomandibular joint impairment,
- fracture or tumors of mandible,
- patients requiring awake intubation,
- uncooperative patients,
Show all 9Show fewer
- any cervical spine limitation movement
- neck swelling or tumor
- Prominent teeth deformities.
Trial locations and contacts
1 site in 1 country.
About this study
the goal of the observational study to measure the effectiveness of neck ultrasound in prediction of difficult intubation in adult patients
Read the detailed description
All participant undergoing elective surgery under general anesthesia will go a detailed preoperative sonographic assessment by the anesthesiologist who has experience in airway ultrasound for measurement of Hyomental distance, thyrohyoid distance, thyroid cricoid, anterior soft tissue thickness at levels of hyoid bone, cricoid cartilage and vocal cord and all measurement will be measured in neutral and sniffing position.
after induction of general anesthesia intubation will done by macintosh laryngoscope and degree of difficulty of intubation will be measured by cormack-lehane classification without any external manipulation
- Conditions
- Difficult Airway
- Keywords
- airway ultrasound
What is being measured
The primary outcome is the main question the study is designed to answer.
measurement of effectiveness of neck ultrasound use of ultrasound measurement in prediction of difficult intubation
In cormack lehan classification of laryngoscopy view
Measured: 30 min after ultrasound measurements at time of induction of anesthesai
Secondary outcomes (12)
Hyomental distance in neutral position
In centimetres
Measured: 30 min before operation
Throhyoid distance in neutral position
In centimetres
Measured: 30 min before operation
Cricothyriod distance in neutral position
In centimetres
Measured: 30 min before operation
Anterior soft tissue thickness at level of hyoid bone in neutral position
In centimetres
Measured: 30 min before opeqrtio
Anterior soft tissue thickness at level of epiglottis in neutral position
In centimetres
Measured: 30 min befor operation
Anterior soft tissue thickness at level of vocal cord in neutral position
In centimetres
Measured: 30 min before operation
Hyomental distance in sniffing position
In centimetres
Measured: 30 min before operation
Thyrohyoid distance in sniffing position
In centimetres
Measured: 30 min before operation
Cricothyroid distance in sniffing position
In centimetres
Measured: 30 minutes before operation
Anterior soft tissue thickness at level of hyoid bone in sniffing position
In centimetres
Measured: 30 min before operation
Anterior soft tissue thickness at level of epiglottis in sniffing position
In centimetres
Measured: 30 min before operation
Anterior soft tissue thickness at level of vocal cord in sniffing position
In centimetres
Measured: 30 min before operation
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted21 Nov 2024
- Study start20 Mar 2023
- Primary completion1 Mar 2026
- Study completion1 Mar 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Difficult AirwayStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 246 participants (actual)
Sponsor and investigators
- Lead sponsor
- National Cancer Institute, Egypt
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- ayman ali ghoneim, MD in anesthesia, Study director, national cancer institute in egypt
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06700265
- Sponsor's protocol ID
- airway ultrasound
- Status last verified
- Apr 2026
- First submitted
- 11 Nov 2024
- Last updated
- 28 Apr 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes
Publications
Parameswari A, Govind M, Vakamudi M. Correlation between preoperative ultrasonographic airway assessment and laryngoscopic view in adult patients: A prospective study. J Anaesthesiol Clin Pharmacol. 2017 Jul-Sep;33(3):353-358. doi: 10.4103/joacp.JOACP_166_17.
PubMed 29109635Roth D, Pace NL, Lee A, Hovhannisyan K, Warenits AM, Arrich J, Herkner H. Airway physical examination tests for detection of difficult airway management in apparently normal adult patients. Cochrane Database Syst Rev. 2018 May 15;5(5):CD008874. doi: 10.1002/14651858.CD008874.pub2.
PubMed 29761867Gomes SH, Simoes AM, Nunes AM, Pereira MV, Teoh WH, Costa PS, Kristensen MS, Teixeira PM, Pego JM. Useful Ultrasonographic Parameters to Predict Difficult Laryngoscopy and Difficult Tracheal Intubation-A Systematic Review and Meta-Analysis. Front Med (Lausanne). 2021 May 28;8:671658. doi: 10.3389/fmed.2021.671658. eCollection 2021.
PubMed 34124099
Study at a glance
From the registry record, last updated by the sponsor on 28 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Ultrasound Airway Examination as a Tool for Detection of Difficult Intubation in Adult Patients
- ClinicalTrials.gov ID
- NCT06700265
- Acronym / sponsor ID
- airway ultrasound
- Conditions
- Difficult Airway
- Keywords
- airway ultrasound
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 246 participants (actual)
- Lead sponsor
- National Cancer Institute, EgyptUniversity, hospital or other
- Study start
- 20 Mar 2023 (actual)
- Primary completion
- 1 Mar 2026 (actual)
- Study completion
- 1 Mar 2026 (actual)
- First posted
- 21 Nov 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
the goal of the observational study to measure the effectiveness of neck ultrasound in prediction of difficult intubation in adult patients
Detailed description
All participant undergoing elective surgery under general anesthesia will go a detailed preoperative sonographic assessment by the anesthesiologist who has experience in airway ultrasound for measurement of Hyomental distance, thyrohyoid distance, thyroid cricoid, anterior soft tissue thickness at levels of hyoid bone, cricoid cartilage and vocal cord and all measurement will be measured in neutral and sniffing position.
after induction of general anesthesia intubation will done by macintosh laryngoscope and degree of difficulty of intubation will be measured by cormack-lehane classification without any external manipulation
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 18 to 70 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- all population undergoining surgical operation requiring general anesthesia and endotracheal intubation
Key inclusion criteria (3 listed)
- Adult patients above18 years old
- Both sex
- Requiring general anesthesia with endotracheal intubation
Key exclusion criteria (9 listed)
- Emergency surgery,
- patients with limited mouth, head or neck movement,
- patients with temporomandibular joint impairment,
- fracture or tumors of mandible,
- patients requiring awake intubation,
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
measurement of effectiveness of neck ultrasound use of ultrasound measurement in prediction of difficult intubation
Time frame: 30 min after ultrasound measurements at time of induction of anesthesai
In cormack lehan classification of laryngoscopy view
12 secondary outcomes
Hyomental distance in neutral position
Time frame: 30 min before operation
Throhyoid distance in neutral position
Time frame: 30 min before operation
Cricothyriod distance in neutral position
Time frame: 30 min before operation
Anterior soft tissue thickness at level of hyoid bone in neutral position
Time frame: 30 min before opeqrtio
Anterior soft tissue thickness at level of epiglottis in neutral position
Time frame: 30 min befor operation
Anterior soft tissue thickness at level of vocal cord in neutral position
Time frame: 30 min before operation
Hyomental distance in sniffing position
Time frame: 30 min before operation
Thyrohyoid distance in sniffing position
Time frame: 30 min before operation
Cricothyroid distance in sniffing position
Time frame: 30 minutes before operation
Anterior soft tissue thickness at level of hyoid bone in sniffing position
Time frame: 30 min before operation
Anterior soft tissue thickness at level of epiglottis in sniffing position
Time frame: 30 min before operation
Anterior soft tissue thickness at level of vocal cord in sniffing position
Time frame: 30 min before operation
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 28 Apr 2026.
- Results publication: PubMed 29109635Parameswari A, Govind M, Vakamudi M. Correlation between preoperative ultrasonographic airway assessment and laryngoscopic view in adult patients: A prospective study. J Anaesthesiol Clin Pharmacol. 2017 Jul-Sep;33(3):353-358. doi: 10.4103/joacp.JOACP_166_17.
- Results publication: PubMed 29761867Roth D, Pace NL, Lee A, Hovhannisyan K, Warenits AM, Arrich J, Herkner H. Airway physical examination tests for detection of difficult airway management in apparently normal adult patients. Cochrane Database Syst Rev. 2018 May 15;5(5):CD008874. doi: 10.1002/14651858.CD008874.pub2.
- Results publication: PubMed 34124099Gomes SH, Simoes AM, Nunes AM, Pereira MV, Teoh WH, Costa PS, Kristensen MS, Teixeira PM, Pego JM. Useful Ultrasonographic Parameters to Predict Difficult Laryngoscopy and Difficult Tracheal Intubation-A Systematic Review and Meta-Analysis. Front Med (Lausanne). 2021 May 28;8:671658. doi: 10.3389/fmed.2021.671658. eCollection 2021.
- Individual participant dataSharing planned: Yes
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
ayman ali ghoneim, MD in anesthesia study director
national cancer institute in egypt
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Difficult Airway, run by National Cancer Institute, Egypt at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 9 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 28 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
measurement of effectiveness of neck ultrasound use of ultrasound measurement in prediction of difficult intubation (time frame: 30 min after ultrasound measurements at time of induction of anesthesai). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06700265, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 28 Apr 2026.