Occupational Exposure to ChemicalsDAISY-ExpoNCT06709989
Chemical and Microbiological Exposure of Women on Dairy Cattle Farms
An observational study of Occupational Exposure to Chemicals, run by Institut National de la Santé Et de la Recherche Médicale, France at 1 site in France.
Trial summary
Although professionals working on dairy cattle farms come into contact with a wide range of chemicals and microbiological agents, little is known about this possible exposure, which occurs a priori via inhalation and skin contact. Read more about this study
- Who is it for?
- Ages 18 years and older, women onlyHealthy volunteers can take part
- Conditions the study is for
- Occupational Exposure to Chemicals
- How many people
- 80 participants
- Where
- 1 siteFrance
- Study dates
- 3 Jan 2025to Jan 2028
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- Women only
- Healthy volunteers accepted
- Adult, Older adult
Study population: Adult women working on dairy cattle farms in West area of France
Who may be able to join
- Adult woman working on a dairy cattle farm in the "Grand Ouest" region of France
- Woman who speaks and understands French
Who cannot join
- working less than 20h/week in dairy farms
- Woman under legal protection
- unsigned consent form
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Expositions Chimique et Microbiologique Des Femmes Dans Les Exploitations Bovines laitières
Although professionals working on dairy cattle farms come into contact with a wide range of chemicals and microbiological agents, little is known about this possible exposure, which occurs a priori via inhalation and skin contact.
The aim of this research is to gain a better understanding of this chemical and microbiological exposure, and this research focuses in particular on professional women working on dairy cattle farms , who may be in charge of specific activities not commonly carried out by professional men.
Exposure to pesticides, antiparasitic products and disinfectants will be the first substances to be investigated, followed by other chemical or particulate compounds present in everyday and professional environments. Exposure to these compounds will be measured by their presence in the urine, feces (if possible) and hair of around 60 participating women, as well as in bovine tuft/head hair and, if possible, air samples taken in milking buildings.
- Conditions
- Occupational Exposure to Chemicals
- Keywords
- farmer, women, occupational exposure, chemicals, pesticides, biocides
What is being measured
The primary outcome is the main question the study is designed to answer.
Exposure to chemicals of women working on dairy farms
Concentrations of pesticide molecules, biocides, disinfectants and microbiological agents, measured in
- urines of professional women working on dairy farms,
- the hair of professional women working on dairy farms,
- faeces of professional women from dairy farms,
- tuft/head hair from females in the herd on farms where female professionals work,
- environmental samples of pesticide molecules (PPPs, pesticides), biocides, disinfectants and microbiological agents.
Measured: At inclusion and at the end of the follow-up (for hair-concentrations), and during specific periods of agricultural activities (with two 4-day periods of urine sample collection, one period of faeces collection, and one week of environmental sampling)
Secondary outcomes (1)
Exposure to other chemicals
Concentrations measured in urine, hair, feces, toupillon/head hair and environmental samples from the farm of other chemical compounds present in the participants' professional uses and environments.
Measured: At inclusion and at the end of the follow-up (for hair-concentrations), and during specific periods of agricultural activities (with two 4-day periods of urine sample collection, one period of faeces collection, and one week of environmental sampling)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted29 Nov 2024
- Study start3 Jan 2025
- Primary completionJan 2028 (estimated)
- Study completionJan 2028 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Occupational Exposure to ChemicalsStudies of the same condition, open and under way.
- More trials run by Institut National de la Santé Et de la Recherche Médicale, FranceThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 80 participants (estimated)
Sponsor and investigators
- Sponsor type
- Other government
- Collaborators
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Ecole des Hautes Etudes en Santé Publique
- Responsible party
- Sponsor
- Investigators
- Cecile Chevrier, Principal investigator, Inserm UMR1085 Irset
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06709989
- Sponsor's protocol ID
- C23-69
- Other IDs
- 2024-A00966-41
- Acronym
- DAISY-Expo
- Status last verified
- Mar 2026
- First submitted
- 14 Nov 2024
- Last updated
- 9 Mar 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: No or required a additional/new ethic authorization
Study at a glance
From the registry record, last updated by the sponsor on 9 Mar 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Expositions Chimique et Microbiologique Des Femmes Dans Les Exploitations Bovines laitières
- ClinicalTrials.gov ID
- NCT06709989
- Acronym / sponsor ID
- DAISY-Expo / C23-69
- Conditions
- Occupational Exposure to Chemicals
- Keywords
- farmer, women, occupational exposure, chemicals, pesticides, biocides
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 80 participants (estimated)
- Lead sponsor
- Institut National de la Santé Et de la Recherche Médicale, FranceOther government
- Collaborators
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, Ecole des Hautes Etudes en Santé Publique
- Study start
- 3 Jan 2025 (actual)
- Primary completion
- Jan 2028 (estimated)
- Study completion
- Jan 2028 (estimated)
- First posted
- 29 Nov 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Although professionals working on dairy cattle farms come into contact with a wide range of chemicals and microbiological agents, little is known about this possible exposure, which occurs a priori via inhalation and skin contact.
The aim of this research is to gain a better understanding of this chemical and microbiological exposure, and this research focuses in particular on professional women working on dairy cattle farms , who may be in charge of specific activities not commonly carried out by professional men.
Exposure to pesticides, antiparasitic products and disinfectants will be the first substances to be investigated, followed by other chemical or particulate compounds present in everyday and professional environments. Exposure to these compounds will be measured by their presence in the urine, feces (if possible) and hair of around 60 participating women, as well as in bovine tuft/head hair and, if possible, air samples taken in milking buildings.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Ages
- 18 years and older
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Adult women working on dairy cattle farms in West area of France
Key inclusion criteria (2 listed)
- Adult woman working on a dairy cattle farm in the "Grand Ouest" region of France
- Woman who speaks and understands French
Key exclusion criteria (3 listed)
- working less than 20h/week in dairy farms
- Woman under legal protection
- unsigned consent form
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Exposure to chemicals of women working on dairy farms
Time frame: At inclusion and at the end of the follow-up (for hair-concentrations), and during specific periods of agricultural activities (with two 4-day periods of urine sample collection, one period of faeces collection, and one week of environmental sampling)
Concentrations of pesticide molecules, biocides, disinfectants and microbiological agents, measured in * urines of professional women working on dairy farms, * the hair of professional women working on dairy farms, * faeces of professional women from dairy farms, * tuft/head hair from females in the herd on farms where female professionals work, * environmental samples of pesticide molecules (PPPs, pesticides), biocides, disinfectants and microbiological agents.
1 secondary outcome
Exposure to other chemicals
Time frame: At inclusion and at the end of the follow-up (for hair-concentrations), and during specific periods of agricultural activities (with two 4-day periods of urine sample collection, one period of faeces collection, and one week of environmental sampling)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Mar 2026.
- Individual participant dataSharing planned: No. No or required a additional/new ethic authorization
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Cecile Chevrier principal investigator
Inserm UMR1085 Irset
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Occupational Exposure to Chemicals, run by Institut National de la Santé Et de la Recherche Médicale, France at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 9 Mar 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Exposure to chemicals of women working on dairy farms (time frame: At inclusion and at the end of the follow-up (for hair-concentrations), and during specific periods of agricultural activities (with two 4-day periods of urine sample collection, one period of faeces collection, and one week of environmental sampling)). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Mar 2026.