Osteoarthritis ShoulderNCT06729983
Prophylactic Conjoint Tendon Lengthening During Reverse Shoulder Arthroplasty Outcomes
A study testing Prophylactic Conjoint Tendon Lengthening and Standard Reverse Shoulder Arthroplasty in people with Osteoarthritis Shoulder, run by Nickolas Garbis at 1 site in United States.
Trial summary
Some patients may experience persistent pain in the front of their shoulder after reverse shoulder replacement. One of the possible reasons for this is that the surgery causes a change in the alignment of the shoulder joint, which may cause increased tension and compression on one of the biceps tendon called the… Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Osteoarthritis Shoulder
- What is being tested?
- Prophylactic Conjoint Tendon Lengthening and Standard Reverse Shoulder Arthroplasty
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 110 participants
- Where
- 1 siteUnited States
- Study dates
- Mar 2025to Mar 2029
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Patients who are at least 18 years old undergoing primary reverse total shoulder arthroplasty
- Operations that occur at Loyola University Medical Center (Maywood, IL), Loyola Ambulatory Surgery Center (Maywood, IL), or Gottlieb Memorial Hospital
Who cannot join
- Patients younger than 18 years old
- Patients who had prior coracoid transfer procedure
- Patients who are undergoing revision surgery from a prior arthroplasty
- Current pregnancy As per standard protocol with all surgeries, a urine pregnancy test is performed prior to surgery. If positive, the surgery will be cancelled and the patient will be excluded from the research study.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Loyola Outpatient Center
Maywood, Illinois, 60153
Nickolas G Garbis, MD, 708-254-5312, ngarbis@lumc.edu
About this study
Official title: Prophylactic Conjoint Tendon Lengthening During Reverse Shoulder Arthroplasty: is There a Difference in Anterior Shoulder Pain At One Year After Surgery?
Some patients may experience persistent pain in the front of their shoulder after reverse shoulder replacement. One of the possible reasons for this is that the surgery causes a change in the alignment of the shoulder joint, which may cause increased tension and compression on one of the biceps tendon called the conjoint tendon. The purpose of this study is to evaluate whether conjoint tendon lengthening, a surgical procedure that involves cutting and lengthening the conjoint tendon in order to reduce tension and compression, is able to prevent or reduce the risk of anterior shoulder pain at one year after surgery.
Read the detailed description
Reverse shoulder arthroplasty (RSA) is a surgical procedure that is used to treat severe shoulder arthritis with rotator cuff damage. RSA involves reversing the ball and socket of the shoulder joint, such that the ball is attached to the shoulder blade and the socket is attached to the upper arm bone. This allows the deltoid muscle to take over the function of the rotator cuff and provide more stability and mobility to the shoulder. RSA has been shown to improve pain, function, and quality of life in patients with various shoulder conditions, such as rotator cuff tear arthropathy, glenohumeral osteoarthritis, complex proximal humeral fractures, pseudoparalysis, and revision shoulder arthroplasty.
However, some patients may experience persistent anterior shoulder pain after RSA, which can limit their function and quality of life. The exact cause and prevalence of this complication are not well understood, but several possible mechanisms have been proposed, such as impingement, instability, infection, nerve injury, fracture, scapular notching, and conjoint tendinitis.
Conjoint tendinitis is a condition where the tendon that connects the coracoid process to the upper arm bone, called the conjoint tendon, becomes inflamed and painful. The conjoint tendon is part of the biceps muscle and the coracobrachialis muscle, and it plays a role in shoulder flexion and internal rotation. Conjoint tendinitis may occur after RSA due to the increased tension and compression on the anterior shoulder caused by the shift in the center of rotation of the joint. Conjoint tendinitis may manifest as anterior shoulder pain, tenderness over the coracoid process, and decreased range of motion and strength.
Conjoint tendon lengthening (CTL) is a surgical procedure that involves cutting or lengthening the conjoint tendon, which may relieve the pain by reducing the tension and compression on the anterior shoulder. CTL can be performed as a primary procedure during RSA, or as a secondary procedure after RSA. The rationale for performing CTL as a primary procedure is to prevent the development of conjoint tendinitis and anterior shoulder pain after RSA. The rationale for performing CTL as a secondary procedure is to treat the patients who have failed conservative treatments, such as physical therapy, injections, or medications, and have persistent anterior shoulder pain after RSA.
The literature on CTL for anterior shoulder pain after RSA is scarce and mostly consists of case reports and case series. There is no randomized controlled trial or systematic review on this topic. The existing studies have reported favorable results of CTL, with improvement in pain, function, and patient-reported outcomes. However, the studies have also acknowledged the limitations of their methods, such as small sample size, lack of control group, short follow-up, and potential bias. Therefore, the evidence for the effectiveness of CTL for anterior shoulder pain after RSA is weak and inconclusive.
The gap or problem that this research aims to address is the lack of high-quality evidence on the effectiveness of prophylactic CTL during RSA for preventing or reducing anterior shoulder pain at one year after surgery. The investigators hypothesize that patients who undergo prophylactic CTL during RSA will have less anterior shoulder pain at one year after surgery than those who do not. The investigators will test this hypothesis by conducting a randomized controlled trial with two groups: CTL group and control group. The investigators will compare the pain intensity, range of motion, strength, activity level, and patient-reported outcomes of the two groups at 6 months and 12 months after RSA. The investigators will also identify the factors that predict the response to CTL, such as age, gender, body mass index, comorbidities, duration of pain, and severity of arthritis. This research will contribute to the knowledge in the field of shoulder surgery by providing high-quality evidence on the effectiveness of prophylactic CTL during RSA for anterior shoulder pain. This research will also have practical implications for the field of shoulder surgery by providing a viable option for patients who suffer from anterior shoulder pain after RSA, and enhancing their function and quality of life.
- Conditions
- Osteoarthritis Shoulder
- Being tested
- Prophylactic Conjoint Tendon Lengthening, Standard Reverse Shoulder Arthroplasty
- Keywords
- reverse shoulder athroplasty, conjoint tendon lengthening, pain outcome
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Prophylactic Conjoint Tendon LengtheningProcedure or surgery
During a standard reverse shoulder arthroplasty procedure, the conjoint tendon will be incised and lengthened prophylactically
Standard Reverse Shoulder ArthroplastyProcedure or surgery
A standard reverse shoulder arthroplasty procedure will be performed
| Study group | Role | What they receive |
|---|---|---|
| Control | Active comparator | Standard reverse shoulder arthroplasty Receives: Procedure: Standard Reverse Shoulder Arthroplasty |
| Treatment | Experimental | Prophylactic conjoint tendon lengthening in addition to reverse shoulder arthroplasty Receives: Procedure: Prophylactic Conjoint Tendon Lengthening |
What is being measured
The primary outcome is the main question the study is designed to answer.
American Society of Shoulder and Elbow Surgeons (ASES) Score
The ASES is a 100-point scale that consists of two dimensions: pain and activities of daily living. There is one pain scale worth 50 points and ten activities of daily living worth 50 points. The higher the points the better the outcome.
Measured: From enrollment to the end of treatment at 12 months
Secondary outcomes (2)
Visual Analog Scale (VAS) Pain Score
The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between "no pain" (0) and "worst pain" (10).
Measured: From enrollment to the end of treatment at 12 months
The Shoulder Pain and Disability Index (SPADI)
The Shoulder Pain and Disability Index (SPADI) is a patient completed questionnaire with 13 items assessing pain level and extent of difficulty with ADLs requiring the use of the upper extremities. The pain subscale has 5-items and the Disability subscale has 8-items. The patient is instructed to choose the number that best describes their level of pain and extent of difficulty using the involved shoulder. The pain scale is summed up to a total of 50 while the disability scale sums up to 80. The total SPADI score is expressed as a percentage. A score of 0 indicates best 100 indicates worst. A higher score shows more disability.
Measured: From enrollment to end of treatment at 12 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted12 Dec 2024
- Study startMar 2025 (estimated)
- Primary completionMar 2028 (estimated)
- Study completionMar 2029 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (12)Papers the sponsor has linked to this study.
- Other trials for Osteoarthritis ShoulderStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 110 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Nickolas Garbis
- Sponsor type
- University, hospital or other
- Collaborators
- Loyola University School of Medicine
- Responsible party
- Sponsor-investigator, Nickolas Garbis, Loyola University
- Investigators
- Nickolas G Garbis, MD, Principal investigator, Loyola University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06729983
- Sponsor's protocol ID
- 218607
- Status last verified
- Mar 2025
- First submitted
- 9 Dec 2024
- Last updated
- 7 Mar 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: This is a single cite study
Publications
Werner BC, Chang B, Nguyen JT, Dines DM, Gulotta LV. What Change in American Shoulder and Elbow Surgeons Score Represents a Clinically Important Change After Shoulder Arthroplasty? Clin Orthop Relat Res. 2016 Dec;474(12):2672-2681. doi: 10.1007/s11999-016-4968-z. Epub 2016 Jul 8.
PubMed 27392769Vij N, Tummala S, Shahriary E, Tokish J, Martin S. Total Shoulder Arthroplasty Versus Reverse Shoulder Arthroplasty in Primary Glenohumeral Osteoarthritis With Intact Rotator Cuffs: A Meta-Analyses. Cureus. 2024 Apr 8;16(4):e57866. doi: 10.7759/cureus.57866. eCollection 2024 Apr.
PubMed 38725735Gomez GV, Huffman GR. Conjoint tendon lengthening for recalcitrant anterior shoulder pain after reverse shoulder arthroplasty: a technique article. JSES Rev Rep Tech. 2022 Jan 13;2(2):164-167. doi: 10.1016/j.xrrt.2021.12.005. eCollection 2022 May.
PubMed 37587959Tashjian RZ, Frandsen JJ, Christensen GV, Chalmers PN. Conjoint tendon release for persistent anterior shoulder pain following reverse total shoulder arthroplasty. JSES Int. 2020 Jul 31;4(4):975-978. doi: 10.1016/j.jseint.2020.07.005. eCollection 2020 Dec.
PubMed 33345243Boileau P, Melis B, Duperron D, Moineau G, Rumian AP, Han Y. Revision surgery of reverse shoulder arthroplasty. J Shoulder Elbow Surg. 2013 Oct;22(10):1359-70. doi: 10.1016/j.jse.2013.02.004. Epub 2013 May 22.
PubMed 23706884Black EM, Roberts SM, Siegel E, Yannopoulos P, Higgins LD, Warner JJ. Failure after reverse total shoulder arthroplasty: what is the success of component revision? J Shoulder Elbow Surg. 2015 Dec;24(12):1908-14. doi: 10.1016/j.jse.2015.05.029. Epub 2015 Jul 7.
PubMed 26163279Anakwenze OA, Kancherla VK, Carolan GF, Abboud J. Coracoid fracture after reverse total shoulder arthroplasty: a report of 2 cases. Am J Orthop (Belle Mead NJ). 2015 Nov;44(11):E469-72.
PubMed 26566565Schwartz DG, Kang SH, Lynch TS, Edwards S, Nuber G, Zhang LQ, Saltzman M. The anterior deltoid's importance in reverse shoulder arthroplasty: a cadaveric biomechanical study. J Shoulder Elbow Surg. 2013 Mar;22(3):357-64. doi: 10.1016/j.jse.2012.02.002. Epub 2012 May 19.
PubMed 22608931Schairer WW, Nwachukwu BU, Lyman S, Craig EV, Gulotta LV. National utilization of reverse total shoulder arthroplasty in the United States. J Shoulder Elbow Surg. 2015 Jan;24(1):91-7. doi: 10.1016/j.jse.2014.08.026. Epub 2014 Oct 29.
PubMed 25440519Kim SH, Wise BL, Zhang Y, Szabo RM. Increasing incidence of shoulder arthroplasty in the United States. J Bone Joint Surg Am. 2011 Dec 21;93(24):2249-54. doi: 10.2106/JBJS.J.01994.
PubMed 22258770Grammont PM, Baulot E. The classic: Delta shoulder prosthesis for rotator cuff rupture. 1993. Clin Orthop Relat Res. 2011 Sep;469(9):2424. doi: 10.1007/s11999-011-1960-5. No abstract available.
PubMed 21732025Drake GN, O'Connor DP, Edwards TB. Indications for reverse total shoulder arthroplasty in rotator cuff disease. Clin Orthop Relat Res. 2010 Jun;468(6):1526-33. doi: 10.1007/s11999-009-1188-9.
PubMed 20049573
Study at a glance
From the registry record, last updated by the sponsor on 7 Mar 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Prophylactic Conjoint Tendon Lengthening During Reverse Shoulder Arthroplasty: is There a Difference in Anterior Shoulder Pain At One Year After Surgery?
- ClinicalTrials.gov ID
- NCT06729983
- Acronym / sponsor ID
- 218607
- Conditions
- Osteoarthritis Shoulder
- Keywords
- reverse shoulder athroplasty, conjoint tendon lengthening, pain outcome
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 110 participants (estimated)
- Lead sponsor
- Nickolas GarbisUniversity, hospital or other
- Collaborators
- Loyola University School of Medicine
- Study start
- Mar 2025 (estimated)
- Primary completion
- Mar 2028 (estimated)
- Study completion
- Mar 2029 (estimated)
- First posted
- 12 Dec 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Some patients may experience persistent pain in the front of their shoulder after reverse shoulder replacement. One of the possible reasons for this is that the surgery causes a change in the alignment of the shoulder joint, which may cause increased tension and compression on one of the biceps tendon called the conjoint tendon. The purpose of this study is to evaluate whether conjoint tendon lengthening, a surgical procedure that involves cutting and lengthening the conjoint tendon in order to reduce tension and compression, is able to prevent or reduce the risk of anterior shoulder pain at one year after surgery.
Detailed description
Reverse shoulder arthroplasty (RSA) is a surgical procedure that is used to treat severe shoulder arthritis with rotator cuff damage. RSA involves reversing the ball and socket of the shoulder joint, such that the ball is attached to the shoulder blade and the socket is attached to the upper arm bone. This allows the deltoid muscle to take over the function of the rotator cuff and provide more stability and mobility to the shoulder. RSA has been shown to improve pain, function, and quality of life in patients with various shoulder conditions, such as rotator cuff tear arthropathy, glenohumeral osteoarthritis, complex proximal humeral fractures, pseudoparalysis, and revision shoulder arthroplasty.
However, some patients may experience persistent anterior shoulder pain after RSA, which can limit their function and quality of life. The exact cause and prevalence of this complication are not well understood, but several possible mechanisms have been proposed, such as impingement, instability, infection, nerve injury, fracture, scapular notching, and conjoint tendinitis.
Conjoint tendinitis is a condition where the tendon that connects the coracoid process to the upper arm bone, called the conjoint tendon, becomes inflamed and painful. The conjoint tendon is part of the biceps muscle and the coracobrachialis muscle, and it plays a role in shoulder flexion and internal rotation. Conjoint tendinitis may occur after RSA due to the increased tension and compression on the anterior shoulder caused by the shift in the center of rotation of the joint. Conjoint tendinitis may manifest as anterior shoulder pain, tenderness over the coracoid process, and decreased range of motion and strength.
Conjoint tendon lengthening (CTL) is a surgical procedure that involves cutting or lengthening the conjoint tendon, which may relieve the pain by reducing the tension and compression on the anterior shoulder. CTL can be performed as a primary procedure during RSA, or as a secondary procedure after RSA. The rationale for performing CTL as a primary procedure is to prevent the development of conjoint tendinitis and anterior shoulder pain after RSA. The rationale for performing CTL as a secondary procedure is to treat the patients who have failed conservative treatments, such as physical therapy, injections, or medications, and have persistent anterior shoulder pain after RSA.
The literature on CTL for anterior shoulder pain after RSA is scarce and mostly consists of case reports and case series. There is no randomized controlled trial or systematic review on this topic. The existing studies have reported favorable results of CTL, with improvement in pain, function, and patient-reported outcomes. However, the studies have also acknowledged the limitations of their methods, such as small sample size, lack of control group, short follow-up, and potential bias. Therefore, the evidence for the effectiveness of CTL for anterior shoulder pain after RSA is weak and inconclusive.
The gap or problem that this research aims to address is the lack of high-quality evidence on the effectiveness of prophylactic CTL during RSA for preventing or reducing anterior shoulder pain at one year after surgery. The investigators hypothesize that patients who undergo prophylactic CTL during RSA will have less anterior shoulder pain at one year after surgery than those who do not. The investigators will test this hypothesis by conducting a randomized controlled trial with two groups: CTL group and control group. The investigators will compare the pain intensity, range of motion, strength, activity level, and patient-reported outcomes of the two groups at 6 months and 12 months after RSA. The investigators will also identify the factors that predict the response to CTL, such as age, gender, body mass index, comorbidities, duration of pain, and severity of arthritis. This research will contribute to the knowledge in the field of shoulder surgery by providing high-quality evidence on the effectiveness of prophylactic CTL during RSA for anterior shoulder pain. This research will also have practical implications for the field of shoulder surgery by providing a viable option for patients who suffer from anterior shoulder pain after RSA, and enhancing their function and quality of life.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Control | Active comparator | Procedure: Standard Reverse Shoulder ArthroplastyStandard reverse shoulder arthroplasty |
| Treatment | Experimental | Procedure: Prophylactic Conjoint Tendon LengtheningProphylactic conjoint tendon lengthening in addition to reverse shoulder arthroplasty |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (2 listed)
- Patients who are at least 18 years old undergoing primary reverse total shoulder arthroplasty
- Operations that occur at Loyola University Medical Center (Maywood, IL), Loyola Ambulatory Surgery Center (Maywood, IL), or Gottlieb Memorial Hospital
Key exclusion criteria (4 listed)
- Patients younger than 18 years old
- Patients who had prior coracoid transfer procedure
- Patients who are undergoing revision surgery from a prior arthroplasty
- Current pregnancy As per standard protocol with all surgeries, a urine pregnancy test is performed prior to surgery. If positive, the surgery will be cancelled and the patient will be excluded from the research study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Prophylactic Conjoint Tendon LengtheningDuring a standard reverse shoulder arthroplasty procedure, the conjoint tendon will be incised and lengthened prophylactically | Procedure or surgery | Treatment |
| Standard Reverse Shoulder ArthroplastyA standard reverse shoulder arthroplasty procedure will be performed | Procedure or surgery | Control |
Primary outcome
American Society of Shoulder and Elbow Surgeons (ASES) Score
Time frame: From enrollment to the end of treatment at 12 months
The ASES is a 100-point scale that consists of two dimensions: pain and activities of daily living. There is one pain scale worth 50 points and ten activities of daily living worth 50 points. The higher the points the better the outcome.
2 secondary outcomes
Visual Analog Scale (VAS) Pain Score
Time frame: From enrollment to the end of treatment at 12 months
The Shoulder Pain and Disability Index (SPADI)
Time frame: From enrollment to end of treatment at 12 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 7 Mar 2025.
- Background: PubMed 27392769Werner BC, Chang B, Nguyen JT, Dines DM, Gulotta LV. What Change in American Shoulder and Elbow Surgeons Score Represents a Clinically Important Change After Shoulder Arthroplasty? Clin Orthop Relat Res. 2016 Dec;474(12):2672-2681. doi: 10.1007/s11999-016-4968-z. Epub 2016 Jul 8.
- Background: PubMed 38725735Vij N, Tummala S, Shahriary E, Tokish J, Martin S. Total Shoulder Arthroplasty Versus Reverse Shoulder Arthroplasty in Primary Glenohumeral Osteoarthritis With Intact Rotator Cuffs: A Meta-Analyses. Cureus. 2024 Apr 8;16(4):e57866. doi: 10.7759/cureus.57866. eCollection 2024 Apr.
- Background: PubMed 37587959Gomez GV, Huffman GR. Conjoint tendon lengthening for recalcitrant anterior shoulder pain after reverse shoulder arthroplasty: a technique article. JSES Rev Rep Tech. 2022 Jan 13;2(2):164-167. doi: 10.1016/j.xrrt.2021.12.005. eCollection 2022 May.
- Background: PubMed 33345243Tashjian RZ, Frandsen JJ, Christensen GV, Chalmers PN. Conjoint tendon release for persistent anterior shoulder pain following reverse total shoulder arthroplasty. JSES Int. 2020 Jul 31;4(4):975-978. doi: 10.1016/j.jseint.2020.07.005. eCollection 2020 Dec.
- Background: PubMed 23706884Boileau P, Melis B, Duperron D, Moineau G, Rumian AP, Han Y. Revision surgery of reverse shoulder arthroplasty. J Shoulder Elbow Surg. 2013 Oct;22(10):1359-70. doi: 10.1016/j.jse.2013.02.004. Epub 2013 May 22.
- Background: PubMed 26163279Black EM, Roberts SM, Siegel E, Yannopoulos P, Higgins LD, Warner JJ. Failure after reverse total shoulder arthroplasty: what is the success of component revision? J Shoulder Elbow Surg. 2015 Dec;24(12):1908-14. doi: 10.1016/j.jse.2015.05.029. Epub 2015 Jul 7.
- Background: PubMed 26566565Anakwenze OA, Kancherla VK, Carolan GF, Abboud J. Coracoid fracture after reverse total shoulder arthroplasty: a report of 2 cases. Am J Orthop (Belle Mead NJ). 2015 Nov;44(11):E469-72.
- Background: PubMed 22608931Schwartz DG, Kang SH, Lynch TS, Edwards S, Nuber G, Zhang LQ, Saltzman M. The anterior deltoid's importance in reverse shoulder arthroplasty: a cadaveric biomechanical study. J Shoulder Elbow Surg. 2013 Mar;22(3):357-64. doi: 10.1016/j.jse.2012.02.002. Epub 2012 May 19.
- Background: PubMed 25440519Schairer WW, Nwachukwu BU, Lyman S, Craig EV, Gulotta LV. National utilization of reverse total shoulder arthroplasty in the United States. J Shoulder Elbow Surg. 2015 Jan;24(1):91-7. doi: 10.1016/j.jse.2014.08.026. Epub 2014 Oct 29.
- Background: PubMed 22258770Kim SH, Wise BL, Zhang Y, Szabo RM. Increasing incidence of shoulder arthroplasty in the United States. J Bone Joint Surg Am. 2011 Dec 21;93(24):2249-54. doi: 10.2106/JBJS.J.01994.
- Background: PubMed 21732025Grammont PM, Baulot E. The classic: Delta shoulder prosthesis for rotator cuff rupture. 1993. Clin Orthop Relat Res. 2011 Sep;469(9):2424. doi: 10.1007/s11999-011-1960-5. No abstract available.
- Background: PubMed 20049573Drake GN, O'Connor DP, Edwards TB. Indications for reverse total shoulder arthroplasty in rotator cuff disease. Clin Orthop Relat Res. 2010 Jun;468(6):1526-33. doi: 10.1007/s11999-009-1188-9.
- Individual participant dataSharing planned: No. This is a single cite study
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Nickolas G Garbis, MD principal investigator
Loyola University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Prophylactic Conjoint Tendon Lengthening and Standard Reverse Shoulder Arthroplasty in people with Osteoarthritis Shoulder, run by Nickolas Garbis at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 7 Mar 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Nickolas G Garbis, MD (708-254-5312, ngarbis@lumc.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
American Society of Shoulder and Elbow Surgeons (ASES) Score (time frame: From enrollment to the end of treatment at 12 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06729983, which also lists 12 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 7 Mar 2025.