Regression EquationNCT06753201
Prediction of New Regression Equation Among a Group of Egyptian Children
An observational study of Regression Equation and Teeth Measurement, run by Cairo University.
Trial summary
Aim of the study: Prediction of new regression equation using digital analysis for determination of mesiodistal width of permanent teeth among a group of Egyptian children. Research question What is the combined mesiodistal dimensions of canines and premolars in a group of 12-15 years old Egyptian children and from it… Read more about this study
- Who is it for?
- Ages 12 to 15 yearsHealthy volunteers can take part
- Conditions the study is for
- Regression Equation, Teeth Measurement
- How many people
- 65 participants
- Where
- No sites listed yet
- Study dates
- Jan 2025to Mar 2026
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 12 to 15 years
- All sexes
- Healthy volunteers accepted
- Child
Study population: The study sample will include healthy cooperative children. The children age will range from 12 years to 15 years. They will be selected from the outpatient clinic of Pediatric Dentistry Department of Faculty of Oral and Dental Medicine, Cairo University, according to the following inclusion and exclusion criteria
Who may be able to join
- 1. Subjects age between 12-15 years. 2. Positive subjects acceptance for participation in the study. 3. Full set of the permanent dentition from left 1st permanent molar to right 1st permanent molar.
- 4. Subjects selected with no previous orthodontic treatment to eliminate possibility of any interproximal reduction. 5. Intact marginal ridge
Who cannot join
- 1. Subjects with history of systemic diseases. 2. Subjects who have any sensitivity or adverse reactions to any of used materials.
- 3. Subjects with morphologic anomalous.
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
Sherine E El din, Professor contact
About this study
Official title: Prediction of New Regression Equation Using Digital Analysis for Determination of Mesiodistal Width in Permanent Teeth Among a Group of Egyptian Children : a Cross Section Study
Aim of the study:
Prediction of new regression equation using digital analysis for determination of mesiodistal width of permanent teeth among a group of Egyptian children.
Research question What is the combined mesiodistal dimensions of canines and premolars in a group of 12-15 years old Egyptian children and from it Can the new regression equation predict the size of unerupted canines and premolars?
Read the detailed description
Tooth size varies significantly between racial groups so mesiodistal dimension in permanent teeth of Egyptian children differ from any international equation, and to the present data, few studies on the mesiodistal dimension of teeth for Egyptian population (Salem et al., 2023).
Tooth size and shape varies from one person to another, from males and females and from one ethnic group to the other depending on genetic factors (Aljuaid et al., 2021).As mandibular incisors are the first teeth to erupt in the permanent teeth and if their dimensions could perhaps be used for predicting the width of unerupted teeth, then it may be advantageous for analysis of mixed dentition at an early age (Moyers, 1976).Environment and genetics both affect tooth size and it's strongly linked to sex and ethnicity. Males' teeth are larger in size than those of the females and Africans have larger teeth than Europeans (Aldeeb, 2021).
Rationale Tooth size differs among and within populations. Tooth size specifically the mesiodistal dimension has an important role in normal occlusion and in arch space analysis as it affects treatment planning and the final results in orthodontic treatment. (Abozeid et al., 2019). Malocclusion is a common esthetic and functional problem in the world. It's a developmental condition caused by alteration in normal development (Ghorbani et al., 2018). The majority of malocclusion, which starts during the mixed dentition period, can be treated and eliminated in its severity if it was managed early (Abozeid et al., 2019).Predicting the size of canines and premolars that have not yet erupted is essential for accurate diagnosis and planning of the optimal course of action throughout the mixed dentition. The exact forecast reveals the difference between the amount of space needed and that which is now available, providing the first component of a successful therapy (Salem et al., 2023)
- Conditions
- Regression Equation, Teeth Measurement
What is being measured
The primary outcome is the main question the study is designed to answer.
Measuring mesiodistal width in permanent mandibular anterior teeth, maxillary, mandibular canines and premolars among a group of Egyptian children
Measuring mesiodistal width in permanent mandibular anterior teeth, maxillary, mandibular canines and premolars among a group of Egyptian children
Measured: baseline
Secondary outcomes (1)
New regression equation for determination of mesiodistal width of unerupted canines and premolars.
New regression equation for determination of mesiodistal width of unerupted canines and premolars.
Measured: baseline
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted31 Dec 2024
- Study startJan 2025 (estimated)
- Primary completionJan 2026 (estimated)
- Study completionMar 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Regression EquationStudies of the same condition, open and under way.
- More trials run by Cairo UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 65 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Cairo University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Doha Ahmed Ahmed Khalil, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06753201
- Sponsor's protocol ID
- mesiodistal dimension of teeth
- Status last verified
- Dec 2024
- First submitted
- 22 Dec 2024
- Last updated
- 31 Dec 2024
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Publications
Salem, G., Elyazied, M. A., Radwan, E., & Elhiny, O. (2023). New equations for Egyptian children based on Tanaka and Johnston Mixed Dentition Analysis.
Abozeid, H., Shiekh, M. E., & AElsayed, M. (2019a). Determination of the Combined Mesiodistal Widths of the Permanent Mandibular Incisors and that of the Maxillary and Mandibular Canines and Premolars in a Group of Egyptian Children in Suez Governorate: A Cross-sectional study.
Ling JY, Wong RW. Tanaka-Johnston mixed dentition analysis for southern Chinese in Hong Kong. Angle Orthod. 2006 Jul;76(4):632-6. doi: 10.1043/0003-3219(2006)076[0632:TMDAFS]2.0.CO;2.
PubMed 16808570
Study at a glance
From the registry record, last updated by the sponsor on 31 Dec 2024. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Prediction of New Regression Equation Using Digital Analysis for Determination of Mesiodistal Width in Permanent Teeth Among a Group of Egyptian Children : a Cross Section Study
- ClinicalTrials.gov ID
- NCT06753201
- Acronym / sponsor ID
- mesiodistal dimension of teeth
- Conditions
- Regression Equation, Teeth Measurement
- Study type
- Observational
- Recruitment status
- Not yet recruiting
- Enrolment
- 65 participants (estimated)
- Lead sponsor
- Cairo UniversityUniversity, hospital or other
- Study start
- Jan 2025 (estimated)
- Primary completion
- Jan 2026 (estimated)
- Study completion
- Mar 2026 (estimated)
- First posted
- 31 Dec 2024 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Aim of the study:
Prediction of new regression equation using digital analysis for determination of mesiodistal width of permanent teeth among a group of Egyptian children.
Research question What is the combined mesiodistal dimensions of canines and premolars in a group of 12-15 years old Egyptian children and from it Can the new regression equation predict the size of unerupted canines and premolars?
Detailed description
Tooth size varies significantly between racial groups so mesiodistal dimension in permanent teeth of Egyptian children differ from any international equation, and to the present data, few studies on the mesiodistal dimension of teeth for Egyptian population (Salem et al., 2023).
Tooth size and shape varies from one person to another, from males and females and from one ethnic group to the other depending on genetic factors (Aljuaid et al., 2021).As mandibular incisors are the first teeth to erupt in the permanent teeth and if their dimensions could perhaps be used for predicting the width of unerupted teeth, then it may be advantageous for analysis of mixed dentition at an early age (Moyers, 1976).Environment and genetics both affect tooth size and it's strongly linked to sex and ethnicity. Males' teeth are larger in size than those of the females and Africans have larger teeth than Europeans (Aldeeb, 2021).
Rationale Tooth size differs among and within populations. Tooth size specifically the mesiodistal dimension has an important role in normal occlusion and in arch space analysis as it affects treatment planning and the final results in orthodontic treatment. (Abozeid et al., 2019). Malocclusion is a common esthetic and functional problem in the world. It's a developmental condition caused by alteration in normal development (Ghorbani et al., 2018). The majority of malocclusion, which starts during the mixed dentition period, can be treated and eliminated in its severity if it was managed early (Abozeid et al., 2019).Predicting the size of canines and premolars that have not yet erupted is essential for accurate diagnosis and planning of the optimal course of action throughout the mixed dentition. The exact forecast reveals the difference between the amount of space needed and that which is now available, providing the first component of a successful therapy (Salem et al., 2023)
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 12 to 15 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child
- Study population
- The study sample will include healthy cooperative children. The children age will range from 12 years to 15 years. They will be selected from the outpatient clinic of Pediatric Dentistry Department of Faculty of Oral and Dental Medicine, Cairo University, according to the following inclusion and exclusion criteria
Key inclusion criteria (2 listed)
- 1. Subjects age between 12-15 years. 2. Positive subjects acceptance for participation in the study. 3. Full set of the permanent dentition from left 1st permanent molar to right 1st permanent molar.
- 4. Subjects selected with no previous orthodontic treatment to eliminate possibility of any interproximal reduction. 5. Intact marginal ridge
Key exclusion criteria (2 listed)
- 1. Subjects with history of systemic diseases. 2. Subjects who have any sensitivity or adverse reactions to any of used materials.
- 3. Subjects with morphologic anomalous.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Measuring mesiodistal width in permanent mandibular anterior teeth, maxillary, mandibular canines and premolars among a group of Egyptian children
Time frame: baseline
Measuring mesiodistal width in permanent mandibular anterior teeth, maxillary, mandibular canines and premolars among a group of Egyptian children
1 secondary outcome
New regression equation for determination of mesiodistal width of unerupted canines and premolars.
Time frame: baseline
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 31 Dec 2024.
- BackgroundSalem, G., Elyazied, M. A., Radwan, E., & Elhiny, O. (2023). New equations for Egyptian children based on Tanaka and Johnston Mixed Dentition Analysis.
- Results publicationAbozeid, H., Shiekh, M. E., & AElsayed, M. (2019a). Determination of the Combined Mesiodistal Widths of the Permanent Mandibular Incisors and that of the Maxillary and Mandibular Canines and Premolars in a Group of Egyptian Children in Suez Governorate: A Cross-sectional study.
- Results publication: PubMed 16808570Ling JY, Wong RW. Tanaka-Johnston mixed dentition analysis for southern Chinese in Hong Kong. Angle Orthod. 2006 Jul;76(4):632-6. doi: 10.1043/0003-3219(2006)076[0632:TMDAFS]2.0.CO;2.
- Individual participant dataSharing planned: Undecided
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Sherine E El din, Professor contact
Questions about this trial
What is this clinical trial studying?
An observational study of Regression Equation and Teeth Measurement, run by Cairo University.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 31 Dec 2024. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Doha A khalil, master degree (+201061879603, doha_ahmed@dentistry.cu.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Measuring mesiodistal width in permanent mandibular anterior teeth, maxillary, mandibular canines and premolars among a group of Egyptian children (time frame: baseline). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06753201, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 31 Dec 2024.