Maxillary Molar IntrusionNCT06757686
Evaluation of Maxillary Posterior Teeth Intrusion by Skeletally Anchored Mousetrap Appliance in Adult Patient With Anterior Open Bite.
A study testing Mousetrap appliance in people with Maxillary Molar Intrusion, run by Mansoura University at 1 site in Egypt.
Trial summary
Aim of the study: This clinical study aims to evaluate the dental, skeletal, and soft tissue effects of the Mousetrap appliance on the intrusion of maxillary posterior teeth in adult patients with anterior open bite. Read more about this study
- Who is it for?
- Ages 15 to 27 yearsHealthy volunteers can take part
- Conditions the study is for
- Maxillary Molar Intrusion
- What is being tested?
- Mousetrap appliance
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 20 participants
- Where
- 1 siteEgypt
- Study dates
- 25 Aug 2024to 30 Sep 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 15 to 27 years
- All sexes
- Healthy volunteers accepted
- Child, Adult
Who may be able to join
- Age ranging from 15 to 27 years.
- High angle patients with skeletal Class I, II or mild Class III.
- Patients with anterior open bite requiring maxillary posterior teeth intrusion as part of orthodontic treatment.
- Anterior open bite: range from 3-8 mm.
- Healthy adult patients.
- No previous orthodontic treatment.
- No evidence of either periodontal problems, gingival problems, or bruxism, at the beginning of orthodontic treatment.
- No medical problems interfering with orthodontic treatment.
Who cannot join
- Moderate to severe Class III skeletal relationship patients were excluded, as the molars intrusion would lead to increase the severity of Class III malocclusion.
- Patient with bad oral hygiene.
- Periodontal problems.
Trial locations and contacts
1 site in 1 country.
Egypt1 site, 1 recruiting
- Recruiting
Faculty of dentistry, Mansoura university
Al Mansurah, 7650001
Ahmed Kamel Elmorsy, Phd, lecture,orthodontist, ahmedkamel@mans.edu.eg
Marwa Ali Tawfik, prof,Phd,orthodontist, marwaali@mans.edu.eg
About this study
Official title: Evaluation of Maxillary Posterior Teeth Intrusion by Skeletally Anchored Mousetrap Appliance in Adult Patient With Anterior Open Bite
Aim of the study: This clinical study aims to evaluate the dental, skeletal, and soft tissue effects of the Mousetrap appliance on the intrusion of maxillary posterior teeth in adult patients with anterior open bite.
Material and methods: An uncontrolled clinical trial will be conducted involving 20 participants aged 15 to 27 years with skeletal Class I, II, or mild Class III relationships and a measured AOB of 3-8 mm. Participants will receive mini-implants inserted in the anterior palate, with the Mousetrap appliance designed to promote molar intrusion while maintaining vertical dimension. Intraoral scans, radiographs, and clinical photographs will be recorded at baseline and post-intrusion.
Read the detailed description
Aim of the study:
This clinical study will evaluate the dental, skeletal and soft tissue effects of skeletally anchored mousetrap appliance on the intrusion of maxillary posterior teeth in adult patient with anterior open bite.
Materials and methods:
Trial Design: This study will be uncontrolled clinical trial. Intervention All patients will start the treatment by mini-implants insertion in anterior palate. Application of topical and/or local anesthesia, mini-implants will be inserted in anterior palate, using a manual contra-angle driver. The implants are oriented perpendicularly to the palatal curvature. Intraoral scanning for maxillary arch will be recorded before and after intrusion for each patient; at T0 (before intrusion), T1 (after intrusion) appliance construction: the principle of the Mousetrap appliance. For molar intrusion, lever arms are connected to two mini-implants inserted in the anterior palate. A transpalatal arch is placed to avoid tipping of the molars during intrusion. Customized intrusion appliance including upper first molar with band and occlusal rest on posterior teeth. The appliance will be digitally designed. A modified transpalatal arch with a is fitted with sufficient clearance between the palatal mucosa to avoid impingement and irritation during and after successful molar intrusion.
- Conditions
- Maxillary Molar Intrusion
- Being tested
- Mousetrap appliance
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Mousetrap applianceDevice
two mini-implant will be inserted in the palate. then, the mousetrap appliance will be inserted on the mini-implant and activated with power chain.
| Study group | Role | What they receive |
|---|---|---|
| maxillary molar intrusion | Experimental | Not described Receives: Device: Mousetrap appliance |
What is being measured
The primary outcome is the main question the study is designed to answer.
Amount of molar intrusion
The amount of molar intrusion performed, difference in the linear distance from the mesio-buccal cusp of maxillary first permanent molar to the palatal plane, between the pretreatment and post-intrusion cone-beam computed tomography records, will be measured
Measured: 6 months
Secondary outcomes (1)
external root resorption
To calculate the amount of external apical root resorption, each cusp tip and root apex will be precisely detected in all three planes (sagittal, coronal and axial), for all teeth included in the study.
Measured: 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted3 Jan 2025
- Study start25 Aug 2024
- Primary completion25 Sep 2025 (estimated)
- Study completion30 Sep 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Maxillary Molar IntrusionStudies of the same condition, open and under way.
- More trials run by Mansoura UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 20 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Mansoura University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06757686
- Sponsor's protocol ID
- MansouraU
- Status last verified
- Aug 2024
- First submitted
- 27 Dec 2024
- Last updated
- 3 Jan 2025
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Alshannaq WM, Kamel AM, Tawfik MA. Association of bone density, cortical bone thickness, and planned intrabony depth with the accuracy of guided palatal miniscrew insertion in adult patients: A prospective clinical study. Int Orthod. 2026 Oct 28;25(1):101258. doi: 10.1016/j.ortho.2026.101258. Online ahead of print.
PubMed 42950450
Study at a glance
From the registry record, last updated by the sponsor on 3 Jan 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Evaluation of Maxillary Posterior Teeth Intrusion by Skeletally Anchored Mousetrap Appliance in Adult Patient With Anterior Open Bite
- ClinicalTrials.gov ID
- NCT06757686
- Acronym / sponsor ID
- MansouraU
- Conditions
- Maxillary Molar Intrusion
- Study type
- Interventional
- Recruitment status
- Unknown status
- Enrolment
- 20 participants (estimated)
- Lead sponsor
- Mansoura UniversityUniversity, hospital or other
- Study start
- 25 Aug 2024 (actual)
- Primary completion
- 25 Sep 2025 (estimated)
- Study completion
- 30 Sep 2025 (estimated)
- First posted
- 3 Jan 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Aim of the study: This clinical study aims to evaluate the dental, skeletal, and soft tissue effects of the Mousetrap appliance on the intrusion of maxillary posterior teeth in adult patients with anterior open bite.
Material and methods: An uncontrolled clinical trial will be conducted involving 20 participants aged 15 to 27 years with skeletal Class I, II, or mild Class III relationships and a measured AOB of 3-8 mm. Participants will receive mini-implants inserted in the anterior palate, with the Mousetrap appliance designed to promote molar intrusion while maintaining vertical dimension. Intraoral scans, radiographs, and clinical photographs will be recorded at baseline and post-intrusion.
Detailed description
Aim of the study:
This clinical study will evaluate the dental, skeletal and soft tissue effects of skeletally anchored mousetrap appliance on the intrusion of maxillary posterior teeth in adult patient with anterior open bite.
Materials and methods:
Trial Design: This study will be uncontrolled clinical trial. Intervention All patients will start the treatment by mini-implants insertion in anterior palate. Application of topical and/or local anesthesia, mini-implants will be inserted in anterior palate, using a manual contra-angle driver. The implants are oriented perpendicularly to the palatal curvature. Intraoral scanning for maxillary arch will be recorded before and after intrusion for each patient; at T0 (before intrusion), T1 (after intrusion) appliance construction: the principle of the Mousetrap appliance. For molar intrusion, lever arms are connected to two mini-implants inserted in the anterior palate. A transpalatal arch is placed to avoid tipping of the molars during intrusion. Customized intrusion appliance including upper first molar with band and occlusal rest on posterior teeth. The appliance will be digitally designed. A modified transpalatal arch with a is fitted with sufficient clearance between the palatal mucosa to avoid impingement and irritation during and after successful molar intrusion.
Study design
- Primary purpose
- Treatment
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| maxillary molar intrusion | Experimental | Device: Mousetrap appliance |
Who may qualify
- Ages
- 15 to 27 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult
Key inclusion criteria (8 listed)
- Age ranging from 15 to 27 years.
- High angle patients with skeletal Class I, II or mild Class III.
- Patients with anterior open bite requiring maxillary posterior teeth intrusion as part of orthodontic treatment.
- Anterior open bite: range from 3-8 mm.
- Healthy adult patients.
Key exclusion criteria (3 listed)
- Moderate to severe Class III skeletal relationship patients were excluded, as the molars intrusion would lead to increase the severity of Class III malocclusion.
- Patient with bad oral hygiene.
- Periodontal problems.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Mousetrap appliancetwo mini-implant will be inserted in the palate. then, the mousetrap appliance will be inserted on the mini-implant and activated with power chain. | Device | maxillary molar intrusion |
Primary outcome
Amount of molar intrusion
Time frame: 6 months
The amount of molar intrusion performed, difference in the linear distance from the mesio-buccal cusp of maxillary first permanent molar to the palatal plane, between the pretreatment and post-intrusion cone-beam computed tomography records, will be measured
1 secondary outcome
external root resorption
Time frame: 6 months
Results and safety
Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Jan 2025.
- Derived from this study: PubMed 42950450Alshannaq WM, Kamel AM, Tawfik MA. Association of bone density, cortical bone thickness, and planned intrabony depth with the accuracy of guided palatal miniscrew insertion in adult patients: A prospective clinical study. Int Orthod. 2026 Oct 28;25(1):101258. doi: 10.1016/j.ortho.2026.101258. Online ahead of print.
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Mousetrap appliance in people with Maxillary Molar Intrusion, run by Mansoura University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 8 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: status not confirmed, as of the sponsor's last update on 3 Jan 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
Contact waleed Mostafa Al Shannaq, orthodontist (01507373075 ext. +20, shunnaqwaleed@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Amount of molar intrusion (time frame: 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06757686, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Jan 2025.