Embryo TransferNCT06767202
Relationship Between Exposure to Phenols and Pregnancy Outcomes After Embryo Transfer
An observational study of Embryo Transfer, run by keqin liu at 1 site in China.
Trial summary
The goal of this observational study is to explore the association between phenol exposure and pregnancy outcome after embryo transfer. The main question it aims to answer [is/are]: Whether exposure to phenols is associated with adverse pregnancy outcomes in pregnant women undergoing assisted reproductive technology? Read more about this study
- Who is it for?
- Ages 20 years and older, women onlyHealthy volunteers can take part
- Conditions the study is for
- Embryo Transfer
- How many people
- 1,200 participants
- Where
- 1 siteChina
- Study dates
- 14 Mar 2025to 1 Jul 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 years and older
- Women only
- Healthy volunteers accepted
- Adult, Older adult
Study population: Pregnant women undergoing assisted reproductive technology in Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China from 2024 to 2025
Who may be able to join
- Chinese citizens over the age of 20;
- IVF/ICSI assisted reproductive treatment in our center;
- Complete clinical data, reproductive outcomes and questionnaire data of both sexes;
- Knowing about this research and voluntarily accepting this research;
Who cannot join
- The patient receives sperm or egg donation treatment;
- The patient gave up the egg collection operation due to various reasons, and the cycle was canceled;
- The patient abandons treatment before achieving clinical pregnancy, but the fertile frozen embryo is not transferred;
- There are contraindications to pregnancy, such as serious liver and kidney diseases, malignant tumors, serious mental diseases, uncorrected coagulation function abnormalities or endocrine indicators abnormalities;
- Incomplete or missing clinical data or follow-up data;
Trial locations and contacts
1 site in 1 country.
China1 site
Reproductive center，tongji hospital，huazhong university of science and technology
Wuhan, Hubei, 430030
About this study
The goal of this observational study is to explore the association between phenol exposure and pregnancy outcome after embryo transfer. The main question it aims to answer [is/are]:
Whether exposure to phenols is associated with adverse pregnancy outcomes in pregnant women undergoing assisted reproductive technology?
Read the detailed description
First of all, paper questionnaires were used in this study, including general information questionnaire, health effect questionnaire, health survey summary form, and dietary assessment questionnaire. Secondly, obtain the relevant information of the medical record system, including: assisted reproduction protocol, IVF examination results, B-ultrasound examination results, laboratory test indicators, pregnancy outcome information and newborn information. Finally, urine samples were detected using a high performance liquid chromatography mass spectrometer.
- Conditions
- Embryo Transfer
- Keywords
- Embryo Transfer, Dietary polyphenols, bisphenols
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
| Study group | Role | What they receive |
|---|---|---|
| Pregnant women undergoing assisted reproductive technology in Tongji Hospital, Wuhan City, Hubei Pro | 1. Chinese citizens over the age of 20; 2. IVF/ICSI assisted reproductive treatment in our center; 3. Complete clinical data, reproductive outcomes and questionnaire data of both sexes; 4. Knowing about this research and voluntarily accepting this research; |
What is being measured
The primary outcome is the main question the study is designed to answer.
Rate of clinical pregnancy patients
Rate of biochemical pregnancy, clinical pregnancy and post-natal patients
Measured: From the date of randomization until the termination of pregnancy
Secondary outcomes (1)
Rate of the health newborn
gestational age/preterm birth, physical health at birth, the incidence of systemic abnormalities or diseases, and other health outcomes
Measured: From the date of randomization until the termination of pregnancy
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted9 Jan 2025
- Study start14 Mar 2025
- Primary completion1 Jul 2025
- Study completion1 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Embryo TransferStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 1,200 participants (actual)
Sponsor and investigators
- Lead sponsor
- keqin liu
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, keqin liu, Tongji Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06767202
- Sponsor's protocol ID
- liukeqin0208
- Status last verified
- Jul 2025
- First submitted
- 6 Jan 2025
- Last updated
- 18 Jul 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 18 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Relationship Between Exposure to Phenols and Pregnancy Outcomes After Embryo Transfer
- ClinicalTrials.gov ID
- NCT06767202
- Acronym / sponsor ID
- liukeqin0208
- Conditions
- Embryo Transfer
- Keywords
- Embryo Transfer, Dietary polyphenols, bisphenols
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 1,200 participants (actual)
- Lead sponsor
- keqin liuUniversity, hospital or other
- Study start
- 14 Mar 2025 (actual)
- Primary completion
- 1 Jul 2025 (actual)
- Study completion
- 1 Jul 2025 (actual)
- First posted
- 9 Jan 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this observational study is to explore the association between phenol exposure and pregnancy outcome after embryo transfer. The main question it aims to answer [is/are]:
Whether exposure to phenols is associated with adverse pregnancy outcomes in pregnant women undergoing assisted reproductive technology?
Detailed description
First of all, paper questionnaires were used in this study, including general information questionnaire, health effect questionnaire, health survey summary form, and dietary assessment questionnaire. Secondly, obtain the relevant information of the medical record system, including: assisted reproduction protocol, IVF examination results, B-ultrasound examination results, laboratory test indicators, pregnancy outcome information and newborn information. Finally, urine samples were detected using a high performance liquid chromatography mass spectrometer.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Pregnant women undergoing assisted reproductive technology in Tongji Hospital, Wuhan City, Hubei Pro | – | –1. Chinese citizens over the age of 20; 2. IVF/ICSI assisted reproductive treatment in our center; 3. Complete clinical data, reproductive outcomes and questionnaire data of both sexes; 4. Knowing about this research and voluntarily accepting this research; |
Who may qualify
- Ages
- 20 years and older
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Pregnant women undergoing assisted reproductive technology in Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China from 2024 to 2025
Key inclusion criteria (4 listed)
- Chinese citizens over the age of 20;
- IVF/ICSI assisted reproductive treatment in our center;
- Complete clinical data, reproductive outcomes and questionnaire data of both sexes;
- Knowing about this research and voluntarily accepting this research;
Key exclusion criteria (5 listed)
- The patient receives sperm or egg donation treatment;
- The patient gave up the egg collection operation due to various reasons, and the cycle was canceled;
- The patient abandons treatment before achieving clinical pregnancy, but the fertile frozen embryo is not transferred;
- There are contraindications to pregnancy, such as serious liver and kidney diseases, malignant tumors, serious mental diseases, uncorrected coagulation function abnormalities or endocrine indicators abnormalities;
- Incomplete or missing clinical data or follow-up data;
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Rate of clinical pregnancy patients
Time frame: From the date of randomization until the termination of pregnancy
Rate of biochemical pregnancy, clinical pregnancy and post-natal patients
1 secondary outcome
Rate of the health newborn
Time frame: From the date of randomization until the termination of pregnancy
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Jul 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Embryo Transfer, run by keqin liu at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 18 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Rate of clinical pregnancy patients (time frame: From the date of randomization until the termination of pregnancy). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Jul 2025.