Dynamic Knee ValgusNCT06776562
Effect of Corrective Exercises on Dynamic Knee Valgus
A study testing Exercise in people with Dynamic Knee Valgus and Frontal Plan Projection Angle, run by Medipol University at 1 site in Turkey (Türkiye).
Trial summary
Dynamic knee valgus (DKV) is a movement pattern of the lower limb potentially consisting of a combination of adduction and internal rotation of the femur, knee abduction, tibial anterior translation, tibial external rotation and ankle eversion. Read more about this study
- Who is it for?
- Ages 18 to 25 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Dynamic Knee Valgus, Frontal Plan Projection Angle, Motion Analysis
- What is being tested?
- Exercise
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 33 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 11 Oct 2024to 15 Jun 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 25 years
- Women only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Between 18 and 25 years of age
- Have asymptomatic dynamic knee valgus
- Being woman
Who cannot join
- BMI≥ 30 kg/cm2
- Lower extremity musculoskeletal pain
- Lower extremity injury in the past 1 year
- History of lower limb surgery
- Neurological condition that may affect balance and coordination during the test
- More than half an hour of intense exercise per week
- Those who exercise vigorously for more than half an hour per week
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site, 1 recruiting
- Recruiting
Istanbul Medipol University
Istanbul
İmge Nas, +90444 85 44, i.nas@iku.edu.tr
About this study
Official title: Effect of Corrective Exercises on Lower Extremity Biomechanics and Performance in Asymptomatic Dynamic Knee Valgus
Dynamic knee valgus (DKV) is a movement pattern of the lower limb potentially consisting of a combination of adduction and internal rotation of the femur, knee abduction, tibial anterior translation, tibial external rotation and ankle eversion. Average "normal" performance during a fall jump landing mission knee valgus angle should be in the range of 7-13 degrees in women and 3-8 degrees in men. This faulty movement pattern is a common dysfunction observed in the lower limb during dynamic activities. On the other hand, this is reported to be the underlying mechanism of knee injuries. Changes in knee valgus increase abnormal stresses on the tibiofemoral joint and increase the risk of injuries such as anterior cruciate ligament injuries, patellofemoral pain, iliotibial band syndrome, chronic ankle instability, acute lateral ankle sprains. The main cause of DKV is deficits in neuromuscular control and therefore injury prevention and rehabilitation strategies focus on improving neuromuscular control to avoid these injury mechanisms. There are conflicting results in the literature regarding which of the exercise approaches is superior for DKV, and there is a lack of studies evaluating 2D movement analysis, muscle mechanics and performance of corrective exercise training. Identifying individuals with abnormal movement patterns and those at risk is important to prevent future injuries. The aim of the study was to investigate the effect of corrective exercises on lower extremity biomechanics and performance in individuals with asymptomatic dynamic knee valgus.
- Conditions
- Dynamic Knee Valgus, Frontal Plan Projection Angle, Motion Analysis, Corrective Exercise, MyotonPRO
- Being tested
- Exercise, Control
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ExerciseOther
Education on activities of daily living will be provided. In addition, a program including muscle strengthening, neuromuscular control and flexibility exercises for lower extremity and trunk muscles will be performed. Exercise Program will be performed for 8 weeks, 2 sessions per week.
ControlOther
Education will be provided for activities of daily living. Individuals with dynamic knee valgus in the control group will not receive any intervention. Exercise program will be implemented after the end of the study.
| Study group | Role | What they receive |
|---|---|---|
| Exercise group | Experimental | Intervention includes corrective exercises for dynamic knee valgus Receives: Other: Exercise |
| Control group | Active comparator | The control group will be followed without intervention. Receives: Other: Control |
What is being measured
The primary outcome is the main question the study is designed to answer.
Frontal plan projection angle evaluation
It will be evaluated with the Single Leg Drop Jump test. Kinovea® 2D motion two-dimensional video analysis software will be used to measure the knee-valgus/varus anterior plane projection angle (FPPA).
Measured: Before the intervention, up to 8 weeks
Single leg squat test
During the test, they will be asked to perform a single-leg squat from a static position to at least 60° knee flexion and then return to the starting position. Kinovea® 2D motion two-dimensional video analysis software will be used for the measurement.
Measured: Before the intervention, up to 8 weeks
Viscoelastic properties of muscle
The viscoelastic properties of the participants' muscle will be measured using a myotonometer (MyotonPRO, Tallinn, Estonia). It will be performed on the quadriceps, hamstring, gastrocnemius and hip adductor muscles. Individuals will be asked to contract the muscle and the center of the muscle mass will be identified and marked. The muscle will then be asked to relax. For the measurement, the probe is placed over the muscle, perpendicular to the skin surface, and mechanical force is applied to the subcutaneous tissue for a constant 15 milliseconds. The interval between each pulse is 8 ms and 5 pulses.
Measured: Before the intervention, up to 8 weeks
Secondary outcomes (5)
Static Balance Measurement
Participants will be asked to stand on one foot and to stand on tiptoe with the instruction "rise" and stay in this position. The time will be recorded in seconds.
Measured: Before the intervention, up to 8 weeks
Dynamic Balance Measurement
It will be measured with the "Y balance test". Participants will start by standing on one foot at the midpoint of the linear line with a 120-degree angle between them. With the other foot, they will be asked to touch the anterior, possteromedial and posterolateral direction with their fingertip. The tests will be repeated three times. The distances will be averaged and recorded.
Measured: Before the intervention, up to 8 weeks
Single Leg Forward Jump Test
They will be asked to jump as far as possible with one leg.
Measured: Before the intervention, up to 8 weeks
Three Step Forward Jump Test
They will be asked to perform 3 consecutive maximal jumps forward. The distance from the starting line to the point where the heel touches the ground after completing the third jump will be recorded.
Measured: Before the intervention, up to 8 weeks
Vertical Jump Test
The participant will be asked to jump as far as possible with both feet. The vertical jump distance will be recorded in cm by finding the difference between the jump distance and the arm length.
Measured: Before the intervention, up to 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted15 Jan 2025
- Study start11 Oct 2024
- Primary completion22 Mar 2025 (estimated)
- Study completion15 Jun 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Dynamic Knee ValgusStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Outcomes assessor
- Enrolment
- 33 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Medipol University
- Sponsor type
- University, hospital or other
- Collaborators
- Istanbul Kültür University
- Responsible party
- Principal investigator, Imge NAS, Medipol University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06776562
- Sponsor's protocol ID
- İK-2024-03
- Status last verified
- Jan 2025
- First submitted
- 7 Jan 2025
- Last updated
- 15 Jan 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 15 Jan 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Corrective Exercises on Lower Extremity Biomechanics and Performance in Asymptomatic Dynamic Knee Valgus
- ClinicalTrials.gov ID
- NCT06776562
- Acronym / sponsor ID
- İK-2024-03
- Conditions
- Dynamic Knee Valgus, Frontal Plan Projection Angle, Motion Analysis, Corrective Exercise, MyotonPRO
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 33 participants (estimated)
- Lead sponsor
- Medipol UniversityUniversity, hospital or other
- Collaborators
- Istanbul Kültür University
- Study start
- 11 Oct 2024 (actual)
- Primary completion
- 22 Mar 2025 (estimated)
- Study completion
- 15 Jun 2025 (estimated)
- First posted
- 15 Jan 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Dynamic knee valgus (DKV) is a movement pattern of the lower limb potentially consisting of a combination of adduction and internal rotation of the femur, knee abduction, tibial anterior translation, tibial external rotation and ankle eversion. Average "normal" performance during a fall jump landing mission knee valgus angle should be in the range of 7-13 degrees in women and 3-8 degrees in men. This faulty movement pattern is a common dysfunction observed in the lower limb during dynamic activities. On the other hand, this is reported to be the underlying mechanism of knee injuries. Changes in knee valgus increase abnormal stresses on the tibiofemoral joint and increase the risk of injuries such as anterior cruciate ligament injuries, patellofemoral pain, iliotibial band syndrome, chronic ankle instability, acute lateral ankle sprains. The main cause of DKV is deficits in neuromuscular control and therefore injury prevention and rehabilitation strategies focus on improving neuromuscular control to avoid these injury mechanisms. There are conflicting results in the literature regarding which of the exercise approaches is superior for DKV, and there is a lack of studies evaluating 2D movement analysis, muscle mechanics and performance of corrective exercise training. Identifying individuals with abnormal movement patterns and those at risk is important to prevent future injuries. The aim of the study was to investigate the effect of corrective exercises on lower extremity biomechanics and performance in individuals with asymptomatic dynamic knee valgus.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Exercise group | Experimental | Other: ExerciseIntervention includes corrective exercises for dynamic knee valgus |
| Control group | Active comparator | Other: ControlThe control group will be followed without intervention. |
Who may qualify
- Ages
- 18 to 25 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Between 18 and 25 years of age
- Have asymptomatic dynamic knee valgus
- Being woman
Key exclusion criteria (7 listed)
- BMI≥ 30 kg/cm2
- Lower extremity musculoskeletal pain
- Lower extremity injury in the past 1 year
- History of lower limb surgery
- Neurological condition that may affect balance and coordination during the test
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ExerciseEducation on activities of daily living will be provided. In addition, a program including muscle strengthening, neuromuscular control and flexibility exercises for lower extremity and trunk muscles will be performed. Exercise Program will be performed for 8 weeks, 2 sessions per week. | Other | Exercise group |
| ControlEducation will be provided for activities of daily living. Individuals with dynamic knee valgus in the control group will not receive any intervention. Exercise program will be implemented after the end of the study. | Other | Control group |
Primary outcome
Frontal plan projection angle evaluation
Time frame: Before the intervention, up to 8 weeks
It will be evaluated with the Single Leg Drop Jump test. Kinovea® 2D motion two-dimensional video analysis software will be used to measure the knee-valgus/varus anterior plane projection angle (FPPA).
Single leg squat test
Time frame: Before the intervention, up to 8 weeks
During the test, they will be asked to perform a single-leg squat from a static position to at least 60° knee flexion and then return to the starting position. Kinovea® 2D motion two-dimensional video analysis software will be used for the measurement.
Viscoelastic properties of muscle
Time frame: Before the intervention, up to 8 weeks
The viscoelastic properties of the participants' muscle will be measured using a myotonometer (MyotonPRO, Tallinn, Estonia). It will be performed on the quadriceps, hamstring, gastrocnemius and hip adductor muscles. Individuals will be asked to contract the muscle and the center of the muscle mass will be identified and marked. The muscle will then be asked to relax. For the measurement, the probe is placed over the muscle, perpendicular to the skin surface, and mechanical force is applied to the subcutaneous tissue for a constant 15 milliseconds. The interval between each pulse is 8 ms and 5 pulses.
5 secondary outcomes
Static Balance Measurement
Time frame: Before the intervention, up to 8 weeks
Dynamic Balance Measurement
Time frame: Before the intervention, up to 8 weeks
Single Leg Forward Jump Test
Time frame: Before the intervention, up to 8 weeks
Three Step Forward Jump Test
Time frame: Before the intervention, up to 8 weeks
Vertical Jump Test
Time frame: Before the intervention, up to 8 weeks
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 15 Jan 2025.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Exercise in people with Dynamic Knee Valgus and Frontal Plan Projection Angle, run by Medipol University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 15 Jan 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Each site lists its own contact: choose the nearest one under Trial locations. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Frontal plan projection angle evaluation (time frame: Before the intervention, up to 8 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 15 Jan 2025.