Chronic Low-back PainNCT06778694
Comparative Effects of Motor Control and Isolated Strengthening Lumbar Exercises on Functional Outcomes in Patients with Chronic Low Back Pain
A study testing Isolated strengthening lumbar exercises in people with Chronic Low-back Pain, run by University of Faisalabad.
Trial summary
Comparative effects of motor control and isolated strengthening lumbar exercises on functional outcomes in patients with chronic low back pain Read more about this study
- Who is it for?
- Ages 20 to 50 years
- Conditions the study is for
- Chronic Low-back Pain
- What is being tested?
- Isolated strengthening lumbar exercises
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 35 participants
- Where
- No sites listed yet
- Study dates
- Feb 2025to Aug 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 20 to 50 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- LBP for more than 3 months
- Both male and females.
- Age between 20-50 years old.
- Moderate to severe pain (VAS; 3-7)
- Currently seeking care for LBP.
Who cannot join
- Spinal surgery
- Pregnancy
- Prostatectomy
- Engaged in any sports activities
- Any evidence of nerve root compression
Trial locations and contacts
No sites are listed yet. Contact the study team or a site near you to ask about taking part.
About this study
Comparative effects of motor control and isolated strengthening lumbar exercises on functional outcomes in patients with chronic low back pain
Read the detailed description
As there is an increasing population of low back pain because of the stress and workload that lead to poor posture. Poor posture leads to tightening of flexor muscles and weakness of lumbar extensors that knowns as lower cross syndrome and it will become the chronic low back pain if not treated on time. Most of the therapist only work on the pain management but not focus on the functional outcome of the patient so the isolated lumbar extensor strengthening exercises and motor control exercises should be evaluated to know the effectiveness in improving the functional outcome of patients.
To compare the effects of motor control and isolated strengthening lumbar exercises on functional outcome in patients with chronic low back pain. A randomized controlled trial with a sample of 35 patients with chronic low back pain will be taken from Physiotherapy OPDs of Madinah Teaching Hospital, Allied hospital, In motion physiotherapy clinic and The Physio Rehab clinic. Participants will be randomly divided into two groups using convenient sampling technique. Both groups will be experimental groups. Patients in Group A will do Motor control exercises. Patients in Group B will do isolated strengthening lumbar exercises. Hot pack will be applied for 15 minutes and Ultrasound therapy (1MHz) for 3-5 minutes as baseline treatment in both groups. Patients will be included based on inclusion and exclusion criteria. Assessment will be done by using NPRS and Oswestry disability Index Questionnaire.
- Conditions
- Chronic Low-back Pain
- Being tested
- Motor control exercises, Isolated strengthening lumbar exercises
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Motor control exercisesOther
Bridging Dead bug Plank Pelvic tilts Squatting and lunges
Isolated strengthening lumbar exercisesOther
Child pose Mckenzie Lat pull down Russian twist
| Study group | Role | What they receive |
|---|---|---|
| Group 1 | Experimental | Motor control exercises Receives: Other: Motor control exercises |
| Group 2 | Experimental | Isolated strengthening lumbar exercises Receives: Other: Isolated strengthening lumbar exercises |
What is being measured
The primary outcome is the main question the study is designed to answer.
NPRS
Comparison on effect of pain
Measured: Baseline and after 2 and 4 weeks of treatment
Secondary outcomes (1)
Oswestry disability Questionnaire
Comparison on functional outcome
Measured: Baseline and after 2 and 4 weeks of treatment
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 Jan 2025
- Study startFeb 2025 (estimated)
- Primary completionMay 2025 (estimated)
- Study completionAug 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (5)Papers the sponsor has linked to this study.
- Other trials for Chronic Low-back PainStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 35 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Faisalabad
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Hafiza Ayesha Aslam, University of Faisalabad
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06778694
- Sponsor's protocol ID
- ILEX MCE
- Status last verified
- Feb 2025
- First submitted
- 12 Jan 2025
- Last updated
- 19 Feb 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Saragiotto BT, Maher CG, Yamato TP, Costa LO, Menezes Costa LC, Ostelo RW, Macedo LG. Motor control exercise for chronic non-specific low-back pain. Cochrane Database Syst Rev. 2016 Jan 8;2016(1):CD012004. doi: 10.1002/14651858.CD012004.
PubMed 26742533Fanuscu A, Oz M, Ozel Asliyuce Y, Turhan E, Ulger O. Effects of Clinic-based and Telerehabilitation-based Motor Control Exercises in Individuals with Chronic Low-back Pain: A Randomized Controlled Trial With 3-Month Follow-up. Clin J Pain. 2024 Dec 1;40(12):700-708. doi: 10.1097/AJP.0000000000001245.
PubMed 39285790Steele J, Bruce-Low S, Smith D, Jessop D, Osborne N. Isolated Lumbar Extension Resistance Training Improves Strength, Pain, and Disability, but Not Spinal Height or Shrinkage ("Creep") in Participants with Chronic Low Back Pain. Cartilage. 2020 Apr;11(2):160-168. doi: 10.1177/1947603517695614. Epub 2017 Feb 1.
PubMed 29156985Steele J, Fisher J, Bruce-Low S, Smith D, Osborne N, Newell D. Variability in Strength, Pain, and Disability Changes in Response to an Isolated Lumbar Extension Resistance Training Intervention in Participants with Chronic Low Back Pain. Healthcare (Basel). 2017 Oct 16;5(4):75. doi: 10.3390/healthcare5040075.
PubMed 29035297Fortin M, Rye M, Roussac A, Montpetit C, Burdick J, Naghdi N, Rosenstein B, Bertrand C, Macedo LG, Elliott JM, Dover G, DeMont R, Weber MH, Pepin V. The Effects of Combined Motor Control and Isolated Extensor Strengthening versus General Exercise on Paraspinal Muscle Morphology, Composition, and Function in Patients with Chronic Low Back Pain: A Randomized Controlled Trial. J Clin Med. 2023 Sep 12;12(18):5920. doi: 10.3390/jcm12185920.
PubMed 37762861
Study at a glance
From the registry record, last updated by the sponsor on 19 Feb 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparative Effects of Motor Control and Isolated Strengthening Lumbar Exercises on Functional Outcomes in Patients with Chronic Low Back Pain
- ClinicalTrials.gov ID
- NCT06778694
- Acronym / sponsor ID
- ILEX MCE
- Conditions
- Chronic Low-back Pain
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 35 participants (estimated)
- Lead sponsor
- University of FaisalabadUniversity, hospital or other
- Study start
- Feb 2025 (estimated)
- Primary completion
- May 2025 (estimated)
- Study completion
- Aug 2025 (estimated)
- First posted
- 16 Jan 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Comparative effects of motor control and isolated strengthening lumbar exercises on functional outcomes in patients with chronic low back pain
Detailed description
As there is an increasing population of low back pain because of the stress and workload that lead to poor posture. Poor posture leads to tightening of flexor muscles and weakness of lumbar extensors that knowns as lower cross syndrome and it will become the chronic low back pain if not treated on time. Most of the therapist only work on the pain management but not focus on the functional outcome of the patient so the isolated lumbar extensor strengthening exercises and motor control exercises should be evaluated to know the effectiveness in improving the functional outcome of patients.
To compare the effects of motor control and isolated strengthening lumbar exercises on functional outcome in patients with chronic low back pain. A randomized controlled trial with a sample of 35 patients with chronic low back pain will be taken from Physiotherapy OPDs of Madinah Teaching Hospital, Allied hospital, In motion physiotherapy clinic and The Physio Rehab clinic. Participants will be randomly divided into two groups using convenient sampling technique. Both groups will be experimental groups. Patients in Group A will do Motor control exercises. Patients in Group B will do isolated strengthening lumbar exercises. Hot pack will be applied for 15 minutes and Ultrasound therapy (1MHz) for 3-5 minutes as baseline treatment in both groups. Patients will be included based on inclusion and exclusion criteria. Assessment will be done by using NPRS and Oswestry disability Index Questionnaire.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Group 1 | Experimental | Other: Motor control exercisesMotor control exercises |
| Group 2 | Experimental | Other: Isolated strengthening lumbar exercisesIsolated strengthening lumbar exercises |
Who may qualify
- Ages
- 20 to 50 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- LBP for more than 3 months
- Both male and females.
- Age between 20-50 years old.
- Moderate to severe pain (VAS; 3-7)
- Currently seeking care for LBP.
Key exclusion criteria (5 listed)
- Spinal surgery
- Pregnancy
- Prostatectomy
- Engaged in any sports activities
- Any evidence of nerve root compression
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Motor control exercisesBridging Dead bug Plank Pelvic tilts Squatting and lunges | Other | Group 1 |
| Isolated strengthening lumbar exercisesChild pose Mckenzie Lat pull down Russian twist | Other | Group 2 |
Primary outcome
NPRS
Time frame: Baseline and after 2 and 4 weeks of treatment
Comparison on effect of pain
1 secondary outcome
Oswestry disability Questionnaire
Time frame: Baseline and after 2 and 4 weeks of treatment
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Feb 2025.
- Background: PubMed 26742533Saragiotto BT, Maher CG, Yamato TP, Costa LO, Menezes Costa LC, Ostelo RW, Macedo LG. Motor control exercise for chronic non-specific low-back pain. Cochrane Database Syst Rev. 2016 Jan 8;2016(1):CD012004. doi: 10.1002/14651858.CD012004.
- Background: PubMed 39285790Fanuscu A, Oz M, Ozel Asliyuce Y, Turhan E, Ulger O. Effects of Clinic-based and Telerehabilitation-based Motor Control Exercises in Individuals with Chronic Low-back Pain: A Randomized Controlled Trial With 3-Month Follow-up. Clin J Pain. 2024 Dec 1;40(12):700-708. doi: 10.1097/AJP.0000000000001245.
- Background: PubMed 29156985Steele J, Bruce-Low S, Smith D, Jessop D, Osborne N. Isolated Lumbar Extension Resistance Training Improves Strength, Pain, and Disability, but Not Spinal Height or Shrinkage ("Creep") in Participants with Chronic Low Back Pain. Cartilage. 2020 Apr;11(2):160-168. doi: 10.1177/1947603517695614. Epub 2017 Feb 1.
- Background: PubMed 29035297Steele J, Fisher J, Bruce-Low S, Smith D, Osborne N, Newell D. Variability in Strength, Pain, and Disability Changes in Response to an Isolated Lumbar Extension Resistance Training Intervention in Participants with Chronic Low Back Pain. Healthcare (Basel). 2017 Oct 16;5(4):75. doi: 10.3390/healthcare5040075.
- Background: PubMed 37762861Fortin M, Rye M, Roussac A, Montpetit C, Burdick J, Naghdi N, Rosenstein B, Bertrand C, Macedo LG, Elliott JM, Dover G, DeMont R, Weber MH, Pepin V. The Effects of Combined Motor Control and Isolated Extensor Strengthening versus General Exercise on Paraspinal Muscle Morphology, Composition, and Function in Patients with Chronic Low Back Pain: A Randomized Controlled Trial. J Clin Med. 2023 Sep 12;12(18):5920. doi: 10.3390/jcm12185920.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Questions about this trial
What is this clinical trial studying?
A study testing Isolated strengthening lumbar exercises in people with Chronic Low-back Pain, run by University of Faisalabad.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 19 Feb 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Hafiza Ayesha Aslam Muhammad Aslam (03320628461, ayeshaaslam230800@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
NPRS (time frame: Baseline and after 2 and 4 weeks of treatment). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06778694, which also lists 5 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Feb 2025.