DepressionNCT06793176
Vibraimage Technology for Detecting Depression in Psychiatric Outpatients
An observational study of Depression, run by Peking University People's Hospital at 1 site in China.
Trial summary
Vibraimage technology captures high-frame-rate images of head-neck movements, converting them into vibraimages that display muscle vibration amplitude and frequency. Using algorithms and calculations, it derives an emotional index from these images. Read more about this study
- Who is it for?
- Ages 18 to 70 yearsHealthy volunteers can take part
- Conditions the study is for
- Depression
- What is being tested?
- Video capture
- How many people
- 601 participants
- Where
- 1 siteChina
- Study dates
- 26 Jan 2025to 1 Mar 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 70 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Psychiatric outpatients attending the Beijing Huilongguan Hospital during the study period.
Who may be able to join
- Aged 18 to 70 years.
- No difficulties in reading or writing Chinese; fluent in Mandarin.
- Currently not taking psychotropic medications or on a stable dose for at least 6 weeks.
- Provided informed consent to participate in the study.
Who cannot join
- Schizophrenia.
- Bipolar disorder.
- History of organic brain disease or significant head trauma.
- Presence of severe systemic medical conditions.
- Suicidal ideation or a score ≥3 on Item 3 ("Suicide") of the 17-item Hamilton Depression Rating Scale (HAMD-17).
- Substance dependence or abuse.
- Intellectual disability or dementia.
- Inability to complete video capture or cooperate due to uncontrollable factors (e.g., hyperactivity, Parkinson's disease, or other conditions that prevent remaining still)
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Diagnostic Accuracy of Vibraimage Technology for Detecting Depression in a Psychiatric Outpatient Setting
Vibraimage technology captures high-frame-rate images of head-neck movements, converting them into vibraimages that display muscle vibration amplitude and frequency. Using algorithms and calculations, it derives an emotional index from these images. This non-contact, objective method analyzes psychological indicators through micro-movement detection. An algorithm has been developed to detect depression by calculating 12 emotional and 2 psychophysiological parameters. This diagnostic accuracy study aims to validate the technology's ability to diagnose depression in psychiatric outpatients.
- Conditions
- Depression
- Being tested
- Video capture
- Medical subject headings
- Depression
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Video captureDiagnostic test
A 20-second video capture of head-neck movements at high frame rates is conducted for all participants to obtain high-resolution images. The captured videos are analyzed using an algorithm based on Vibraimage technology to infer whether the participants have depression.
| Study group | Role | What they receive |
|---|---|---|
| Depressed Group | This group consists of individuals who were ultimately diagnosed with depression by a specialist physician. Receives: Diagnostic Test: Video capture | |
| Non-Depressed Group | This group consists of individuals who were ultimately diagnosed as not having depression by a specialist physician. Receives: Diagnostic Test: Video capture |
What is being measured
The primary outcome is the main question the study is designed to answer.
discrimination
The primary outcome measure is the diagnostic discrimination of Vibraimage technology for depression, assessed by calculating the area under the receiver operating characteristic (ROC) curve. Participants first undergo video capture, followed by a clinical diagnosis of depression by a physician. Both the physician and participants are blinded to the results of the video analysis.
Measured: Participants undergo video capture and same-day clinical diagnosis by a physician. Video analysis and suggestive diagnosis are completed on the following day.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Jan 2025
- Study start26 Jan 2025
- Primary completion1 Mar 2025
- Study completion1 Mar 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for DepressionStudies of the same condition, open and under way.
- More trials run by Peking University People's HospitalThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Case-control
- Time perspective
- Prospective
- Enrolment
- 601 participants (actual)
Sponsor and investigators
- Lead sponsor
- Peking University People's Hospital
- Sponsor type
- University, hospital or other
- Collaborators
- Beijing HuiLongGuan Hospital
- Responsible party
- Principal investigator, Yi Feng, MD, Peking University People's Hospital
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06793176
- Sponsor's protocol ID
- Vibraimage_Psychiatric
- Status last verified
- Mar 2025
- First submitted
- 20 Jan 2025
- Last updated
- 5 Mar 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: De-identified individual participant data will be made available to qualified researchers upon reasonable request. Data sharing will be subject to approval by the principal investigator (PI) and the study sponsor.
Publications
Jiang B, Zhang Y, Xie Z, Wu Z, Ma Y, Zhang X, Feng Y. A novel non-contact screening tool based on Vibraimage technology for detecting depressive disorder in psychiatric outpatients: A diagnostic accuracy study. J Affect Disord. 2026 Jan 1;392:120232. doi: 10.1016/j.jad.2025.120232. Epub 2025 Sep 2.
PubMed 40907713
Study at a glance
From the registry record, last updated by the sponsor on 5 Mar 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Diagnostic Accuracy of Vibraimage Technology for Detecting Depression in a Psychiatric Outpatient Setting
- ClinicalTrials.gov ID
- NCT06793176
- Acronym / sponsor ID
- Vibraimage_Psychiatric
- Conditions
- Depression
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 601 participants (actual)
- Lead sponsor
- Peking University People's HospitalUniversity, hospital or other
- Collaborators
- Beijing HuiLongGuan Hospital
- Study start
- 26 Jan 2025 (actual)
- Primary completion
- 1 Mar 2025 (actual)
- Study completion
- 1 Mar 2025 (actual)
- First posted
- 27 Jan 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Vibraimage technology captures high-frame-rate images of head-neck movements, converting them into vibraimages that display muscle vibration amplitude and frequency. Using algorithms and calculations, it derives an emotional index from these images. This non-contact, objective method analyzes psychological indicators through micro-movement detection. An algorithm has been developed to detect depression by calculating 12 emotional and 2 psychophysiological parameters. This diagnostic accuracy study aims to validate the technology's ability to diagnose depression in psychiatric outpatients.
Study design
- Observational model
- Case-control
- Time perspective
- Prospective
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Depressed Group | – | Diagnostic Test: Video captureThis group consists of individuals who were ultimately diagnosed with depression by a specialist physician. |
| Non-Depressed Group | – | Diagnostic Test: Video captureThis group consists of individuals who were ultimately diagnosed as not having depression by a specialist physician. |
Who may qualify
- Ages
- 18 to 70 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Psychiatric outpatients attending the Beijing Huilongguan Hospital during the study period.
Key inclusion criteria (4 listed)
- Aged 18 to 70 years.
- No difficulties in reading or writing Chinese; fluent in Mandarin.
- Currently not taking psychotropic medications or on a stable dose for at least 6 weeks.
- Provided informed consent to participate in the study.
Key exclusion criteria (8 listed)
- Schizophrenia.
- Bipolar disorder.
- History of organic brain disease or significant head trauma.
- Presence of severe systemic medical conditions.
- Suicidal ideation or a score ≥3 on Item 3 ("Suicide") of the 17-item Hamilton Depression Rating Scale (HAMD-17).
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Video captureA 20-second video capture of head-neck movements at high frame rates is conducted for all participants to obtain high-resolution images. The captured videos are analyzed using an algorithm based on Vibraimage technology to infer whether the participants have depression. | Diagnostic test | Depressed Group, Non-Depressed Group |
Primary outcome
discrimination
Time frame: Participants undergo video capture and same-day clinical diagnosis by a physician. Video analysis and suggestive diagnosis are completed on the following day.
The primary outcome measure is the diagnostic discrimination of Vibraimage technology for depression, assessed by calculating the area under the receiver operating characteristic (ROC) curve. Participants first undergo video capture, followed by a clinical diagnosis of depression by a physician. Both the physician and participants are blinded to the results of the video analysis.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 5 Mar 2025.
- Derived from this study: PubMed 40907713Jiang B, Zhang Y, Xie Z, Wu Z, Ma Y, Zhang X, Feng Y. A novel non-contact screening tool based on Vibraimage technology for detecting depressive disorder in psychiatric outpatients: A diagnostic accuracy study. J Affect Disord. 2026 Jan 1;392:120232. doi: 10.1016/j.jad.2025.120232. Epub 2025 Sep 2.
- Individual participant dataSharing planned: Yes. De-identified individual participant data will be made available to qualified researchers upon reasonable request. Data sharing will be subject to approval by the principal investigator (PI) and the study sponsor.
Related trials for Depression
Recruiting
Affective Cognitive Training in Mood Disorders and High-risk Relatives
Major Depressive Disorder (MDD), Bipolar Disorder (BD)
Active, not recruiting
AI Mental Health Tool vs. Psychoeducation Control
Depressive Disorder, Depressive Symptoms
Not yet recruitingObservational study
The Effects of Extreme Prematurity on Parenting
Depression Disorder, Post Traumatic Stress Disorder PTSD
Recruiting
Marine Lipids Ease Painful TMD
Temporomandibular Disorder (TMD)
Recruiting
Restoring Emotional Needs With Exogenous Ketones for Women With Postpartum Depression
Postpartum Depression (PPD)
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Depression, run by Peking University People's Hospital at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 5 Mar 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
discrimination (time frame: Participants undergo video capture and same-day clinical diagnosis by a physician. Video analysis and suggestive diagnosis are completed on the following day.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06793176, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 5 Mar 2025.