Parkinson's Disease (PD)NCT06794177
The Effects of Dual Task Training With Different Task Priorities on Physical Performance and Cognitive Status in Patients With Parkinson's Disease
A study testing Variable priority dual task training, Fixed priority dual task training and Single task training in people with Parkinson's Disease (PD) and Dual-task, run by Hacettepe University at 2 sites in Turkey (Türkiye).
Trial summary
This study was planned to investigate and compare the effects of variable and fixed priority dual task training on balance, walking skills, mobility and cognition in patients with Parkinson's disease. Read more about this study
- Who is it for?
- Ages 40 years and older
- Conditions the study is for
- Parkinson's Disease (PD), Dual-task, Balance
- What is being tested?
- Variable priority dual task training, Fixed priority dual task training and Single task training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 2 sitesTurkey (Türkiye)
- Study dates
- 1 Feb 2024to 30 Sep 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Having agreed to participate in the research after being given detailed information about the research.
- Having been diagnosed with Parkinson's disease by a specialist neurologist according to the UK Brain Bank criteria
- Being in stage 1-3 according to Hoehn \& Yahr
- Being 40 years of age or older
Who cannot join
- Having a neurological condition other than Parkinson's disease
- Cognitive impairment
- Have undergone deep brain stimulation surgery
- Having a visual, auditory or perceptual problem
- Having any orthopedic, rheumatological or other disease that may affect walking and balance.
Trial locations and contacts
2 sites in 1 country.
Turkey (Türkiye)2 sites
Sağlık Bilimleri Üniversitesi, Gülhane Fizyoterapi ve Rehabilitasyon Fakültesi
Ankara, 06018
Gazi Üniversitesi Tıp Fakültesi Nöroloji Anabilim Dalı
Ankara, 06560
About this study
Official title: Investigation of the Effects of Dual Task Training With Different Task Priorities on Physical Performance and Cognitive Status in Patients With Parkinson's Disease
This study was planned to investigate and compare the effects of variable and fixed priority dual task training on balance, walking skills, mobility and cognition in patients with Parkinson's disease.
- Being tested
- Variable priority dual task training, Fixed priority dual task training, Single task training
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Variable priority dual task trainingOther
Variable priority dual task training with balance and walking exercises performed simultaneously with cognitive tasks, twice a week for six weeks
Fixed priority dual task trainingOther
Fixed priority dual task training with balance and walking exercises performed simultaneously with cognitive tasks, twice a week for six weeks
Single task trainingOther
Single task training with balance and walking exercises, twice a week for six weeks
| Study group | Role | What they receive |
|---|---|---|
| Contol Group | Active comparator | Single task training Receives: Other: Single task training |
| Variable priority dual task training group | Experimental | Variable priority dual task training Receives: Other: Variable priority dual task training |
| Fixed priority dual task training group | Experimental | Fixed priority dual task training Receives: Other: Fixed priority dual task training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Hoehn and Yahr Scale
A staging system that quickly provides information in determining the degree and symptom severity of the disease
Measured: Baseline, 6 weeks
Unified Parkinson's Disease Rating Scale
Evaluates cognitive skills, mood, activities of daily living, motor skills, motor fluctuations, dyskinesias, and autonomic dysfunction in four parts
Measured: Baseline, 6 weeks
Berg Balance Scale
It includes 14 functional activities to assess static and proactive balance. The total score ranges from 0 to 56, with higher scores indicating better balance.
Measured: Baseline, 6 weeks
Functional Reach Test
The test is designed to assess dynamic balance by measuring the maximum distance that a person can reach forward beyond arm's length without taking a step.
Measured: Baseline, 6 weeks
Single Leg Stance Test
It is a test method used to evaluate static balance. One foot is lifted without touching the supporting leg and the person is expected to maintain their balance for 30 seconds.
Measured: Baseline, 6 weeks
Four Square Step Test
It is a test method used to evaluate dynamic balance. Two canes are placed on a flat surface to create 4 squares. All squares are numbered. The subject starts in one square and steps in one direction into each of the four squares and then reverses direction back to the start. The time (in seconds) taken to complete the sequence is measured.
Measured: Baseline, 6 weeks
10 Meter Walk Test
Used to assess walking speed. Participants are asked to walk a distance of 10 meters and the time taken is recorded.
Measured: Baseline, 6 weeks
Figure-of-Eight Walk Test
The participant stands still at the midpoint of two cones placed 1.52 m apart and begins walking around the cones in a figure eight at his/her usual pace. The total time and number of steps taken to complete the test are recorded.
Measured: Baseline, 6 weeks
3-Meter Backward Walk Test
The 3-meter distance is measured and marked. Participants are asked to walk backwards as quickly as possible with the "walk" command and to stop when they reach 3 meters. The elapsed time is recorded in seconds.
Measured: Baseline, 6 weeks
Timed Up and Go Test
It is used to assess functional mobility level. The participant is asked to stand up from the chair, walk 3 m, turn around, walk back to the chair and sit down. The test starts with the "walk" command and the completion time is recorded in seconds.
Measured: Baseline, 6 weeks
Unified Parkinson's Disease Rating Scale, Part 2
UPDRS Part 2 generally is considered a psychometrically reliable tool for measuring activities of daily living outcomes in people with Parkinson's disease.
Measured: Baseline, 6 weeks
Dual Task Questionnaire
It is used to obtain information about the difficulties experienced in daily tasks related to dual task. It consists of 10 questions, each question is scored between 0 and 4.
Measured: Baseline, 6 weeks
Trail Making Test
It is used to evaluate individuals' visual scanning speed, executive functions, visual-motor perception, motor function, planning, organization, abstract thinking and response limitation. The test consists of 2 parts: A and B. In part A, the individual is asked to combine numbers from 1 to 25 and the completion time is recorded. In part B, the individual completes the sequence by corresponding to a number and a letter, and the completion time is recorded.
Measured: Baseline, 6 weeks
Stroop Test
It is a test that evaluates executive functions and the suppression of inappropriate automatic responses and provides information about frontal functions.
Measured: Baseline, 6 weeks
Symbol Digit Modalities Test
It is a test that measures working memory and information processing speed. In the upper right corner of the A4 paper used in the test, there is a grid of shapes, each representing a number. In the other parts of the paper, there are randomly arranged shapes in blocks. During the test, patients are asked to match these shapes with the numbers in the grid.
Measured: Baseline, 6 weeks
Word List Generation
It is a test used to evaluate complex attention functions and vocabulary. It consists of animal and KAS sections. First, the patient is asked to name every animal that comes to mind in one minute, as quickly as possible. In the KAS section, the patient is asked to name every word that comes to mind, except for proper nouns and city names, with the letters K-A-S in order. The time for each letter is again one minute.
Measured: Baseline, 6 weeks
Tampa Scale for Kinesiophobia
It is a 17-question scale developed to measure fear of movement/re-injury. The scale includes parameters of injury/re-injury and fear-avoidance in work-related activities. Each item is scored between 1-4.
Measured: Baseline, 6 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Jan 2025
- Study start1 Feb 2024
- Primary completion30 Sep 2025
- Study completion30 Sep 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Parkinson's Disease (PD)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- Hacettepe University
- Sponsor type
- University, hospital or other
- Collaborators
- Gazi University, Saglik Bilimleri Universitesi
- Responsible party
- Principal investigator, Elvan ÖZCAN GÜLŞEN, Hacettepe University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06794177
- Sponsor's protocol ID
- 285
- Status last verified
- Oct 2025
- First submitted
- 21 Jan 2025
- Last updated
- 6 Oct 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Ozcan Gulsen E, Soke F, Gulsen C, Tokcaer Bora HA, Tunca O. The effects of dual-task training with different task priorities on physical performance and cognitive status in patients with Parkinson's disease: a single-blind, randomized controlled trial. Neurol Sci. 2026 Sep 29;47(10):820. doi: 10.1007/s10072-026-09442-1.
PubMed 42809128
Study at a glance
From the registry record, last updated by the sponsor on 6 Oct 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Investigation of the Effects of Dual Task Training With Different Task Priorities on Physical Performance and Cognitive Status in Patients With Parkinson's Disease
- ClinicalTrials.gov ID
- NCT06794177
- Acronym / sponsor ID
- 285
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 30 participants (actual)
- Lead sponsor
- Hacettepe UniversityUniversity, hospital or other
- Collaborators
- Gazi University, Saglik Bilimleri Universitesi
- Study start
- 1 Feb 2024 (actual)
- Primary completion
- 30 Sep 2025 (actual)
- Study completion
- 30 Sep 2025 (actual)
- First posted
- 27 Jan 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study was planned to investigate and compare the effects of variable and fixed priority dual task training on balance, walking skills, mobility and cognition in patients with Parkinson's disease.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Contol Group | Active comparator | Other: Single task trainingSingle task training |
| Variable priority dual task training group | Experimental | Other: Variable priority dual task trainingVariable priority dual task training |
| Fixed priority dual task training group | Experimental | Other: Fixed priority dual task trainingFixed priority dual task training |
Who may qualify
- Ages
- 40 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (4 listed)
- Having agreed to participate in the research after being given detailed information about the research.
- Having been diagnosed with Parkinson's disease by a specialist neurologist according to the UK Brain Bank criteria
- Being in stage 1-3 according to Hoehn \& Yahr
- Being 40 years of age or older
Key exclusion criteria (5 listed)
- Having a neurological condition other than Parkinson's disease
- Cognitive impairment
- Have undergone deep brain stimulation surgery
- Having a visual, auditory or perceptual problem
- Having any orthopedic, rheumatological or other disease that may affect walking and balance.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Variable priority dual task trainingVariable priority dual task training with balance and walking exercises performed simultaneously with cognitive tasks, twice a week for six weeks | Other | Variable priority dual task training group |
| Fixed priority dual task trainingFixed priority dual task training with balance and walking exercises performed simultaneously with cognitive tasks, twice a week for six weeks | Other | Fixed priority dual task training group |
| Single task trainingSingle task training with balance and walking exercises, twice a week for six weeks | Other | Contol Group |
Primary outcome
Hoehn and Yahr Scale
Time frame: Baseline, 6 weeks
A staging system that quickly provides information in determining the degree and symptom severity of the disease
Unified Parkinson's Disease Rating Scale
Time frame: Baseline, 6 weeks
Evaluates cognitive skills, mood, activities of daily living, motor skills, motor fluctuations, dyskinesias, and autonomic dysfunction in four parts
Berg Balance Scale
Time frame: Baseline, 6 weeks
It includes 14 functional activities to assess static and proactive balance. The total score ranges from 0 to 56, with higher scores indicating better balance.
Functional Reach Test
Time frame: Baseline, 6 weeks
The test is designed to assess dynamic balance by measuring the maximum distance that a person can reach forward beyond arm's length without taking a step.
Single Leg Stance Test
Time frame: Baseline, 6 weeks
It is a test method used to evaluate static balance. One foot is lifted without touching the supporting leg and the person is expected to maintain their balance for 30 seconds.
Four Square Step Test
Time frame: Baseline, 6 weeks
It is a test method used to evaluate dynamic balance. Two canes are placed on a flat surface to create 4 squares. All squares are numbered. The subject starts in one square and steps in one direction into each of the four squares and then reverses direction back to the start. The time (in seconds) taken to complete the sequence is measured.
10 Meter Walk Test
Time frame: Baseline, 6 weeks
Used to assess walking speed. Participants are asked to walk a distance of 10 meters and the time taken is recorded.
Figure-of-Eight Walk Test
Time frame: Baseline, 6 weeks
The participant stands still at the midpoint of two cones placed 1.52 m apart and begins walking around the cones in a figure eight at his/her usual pace. The total time and number of steps taken to complete the test are recorded.
3-Meter Backward Walk Test
Time frame: Baseline, 6 weeks
The 3-meter distance is measured and marked. Participants are asked to walk backwards as quickly as possible with the "walk" command and to stop when they reach 3 meters. The elapsed time is recorded in seconds.
Timed Up and Go Test
Time frame: Baseline, 6 weeks
It is used to assess functional mobility level. The participant is asked to stand up from the chair, walk 3 m, turn around, walk back to the chair and sit down. The test starts with the "walk" command and the completion time is recorded in seconds.
Unified Parkinson's Disease Rating Scale, Part 2
Time frame: Baseline, 6 weeks
UPDRS Part 2 generally is considered a psychometrically reliable tool for measuring activities of daily living outcomes in people with Parkinson's disease.
Dual Task Questionnaire
Time frame: Baseline, 6 weeks
It is used to obtain information about the difficulties experienced in daily tasks related to dual task. It consists of 10 questions, each question is scored between 0 and 4.
Trail Making Test
Time frame: Baseline, 6 weeks
It is used to evaluate individuals' visual scanning speed, executive functions, visual-motor perception, motor function, planning, organization, abstract thinking and response limitation. The test consists of 2 parts: A and B. In part A, the individual is asked to combine numbers from 1 to 25 and the completion time is recorded. In part B, the individual completes the sequence by corresponding to a number and a letter, and the completion time is recorded.
Stroop Test
Time frame: Baseline, 6 weeks
It is a test that evaluates executive functions and the suppression of inappropriate automatic responses and provides information about frontal functions.
Symbol Digit Modalities Test
Time frame: Baseline, 6 weeks
It is a test that measures working memory and information processing speed. In the upper right corner of the A4 paper used in the test, there is a grid of shapes, each representing a number. In the other parts of the paper, there are randomly arranged shapes in blocks. During the test, patients are asked to match these shapes with the numbers in the grid.
Word List Generation
Time frame: Baseline, 6 weeks
It is a test used to evaluate complex attention functions and vocabulary. It consists of animal and KAS sections. First, the patient is asked to name every animal that comes to mind in one minute, as quickly as possible. In the KAS section, the patient is asked to name every word that comes to mind, except for proper nouns and city names, with the letters K-A-S in order. The time for each letter is again one minute.
Tampa Scale for Kinesiophobia
Time frame: Baseline, 6 weeks
It is a 17-question scale developed to measure fear of movement/re-injury. The scale includes parameters of injury/re-injury and fear-avoidance in work-related activities. Each item is scored between 1-4.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Oct 2025.
- Derived from this study: PubMed 42809128Ozcan Gulsen E, Soke F, Gulsen C, Tokcaer Bora HA, Tunca O. The effects of dual-task training with different task priorities on physical performance and cognitive status in patients with Parkinson's disease: a single-blind, randomized controlled trial. Neurol Sci. 2026 Sep 29;47(10):820. doi: 10.1007/s10072-026-09442-1.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Variable priority dual task training, Fixed priority dual task training and Single task training in people with Parkinson's Disease (PD) and Dual-task, run by Hacettepe University at 2 sites in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 Oct 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Hoehn and Yahr Scale (time frame: Baseline, 6 weeks). The study lists 17 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06794177, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Oct 2025.