Multiple Pulmonary DiseasesNCT06799455

Uncuffed Endotracheal Tube vs. no Endotracheal Tube

A study testing Endotracheal tube in people with Multiple Pulmonary Diseases, run by University of Minnesota at 1 site in United States.

Terminated

Stopped early. The study ended before it was planned to and will not resume.

Official record

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Trial summary

This is a comparison of uncuffed endotracheal tube (UCETT) vs. no endotracheal tube (ETT) in endobronchial ultrasound-transbronchial needle aspiration (EBUS-TBNA) procedure under moderate sedation in terms of procedure tolerance, duration of the procedure, desaturation, amount of sedation medication usage. Read more about this study

Who is it for?: Ages 18 years and older
Conditions the study is for: Multiple Pulmonary Diseases
What is being tested?: Endotracheal tube
Type of treatment: Medical device
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 4 participants
Where: 1 siteUnited States
Study dates: 2 Jun 2025to 10 Jun 2026
Phase: Interventional
Are there results?: Yes, posted in the registrySummary in the doctors' view

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 18 years and older
All sexes
No healthy volunteers
Adult, Older adult

Who may be able to join

Any patient that is scheduled for EBUS-TBNA procedure

Who cannot join

Those who are not safe to receive moderate sedation or flexible bronchoscopy

Trial locations and contacts

1 site in 1 country.

United States1 site

University of Minnesota
Minneapolis, Minnesota, 55455

Other trials in United States

About this study

Official title: Comparison of Uncuffed Endotracheal Tube to no Endotracheal Tube in EBUS-TBNA Procedure Under Moderate Sedation

Conditions: Multiple Pulmonary Diseases
Being tested: Endotracheal tube

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Endotracheal tubeDevice
participants either receive the ETT during the procedure

Study groups in NCT06799455
Study group	Role	What they receive
uncuffed endotracheal group	Experimental	Not described Receives: Device: Endotracheal tube
no endotracheal tube group/control	No intervention	Not described

What is being measured

The primary outcome is the main question the study is designed to answer.

Desaturation
Whether a patient will experience any desaturation
Measured: During the procedure

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

2 Jun 202510 Jun 2026

First posted29 Jan 2025
Study start2 Jun 2025
Primary completion10 Jun 2026
Study completion10 Jun 2026

Why it stopped: We are closing due to a change in practice here that means we are no longer seeing eligible participants

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Posted resultsParticipant flow, outcome measures and adverse events reported by the sponsor.
Other trials for Multiple Pulmonary DiseasesStudies of the same condition, open and under way.
More trials run by University of MinnesotaThe sponsor's other registered studies.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Health services research
Allocation: Not applicable
Intervention model: Parallel groups
Model description: Patient will be randomized 1:1 to UCETT vs no ETT (current standard procedure) when they scheduled for the EBUS-TBNA procedure.
Masking: None (open label)
Enrolment: 4 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT06799455
Sponsor's protocol ID: PACCS-2024-33033
Status last verified: Aug 2026
First submitted: 23 Jan 2025
Last updated: 22 Sep 2026
Results posted: Yes, on ClinicalTrials.gov
Data monitoring committee: No
FDA-regulated drug: No
FDA-regulated device: Yes

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

See locations

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Study at a glance

From the registry record, last updated by the sponsor on 22 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Comparison of Uncuffed Endotracheal Tube to no Endotracheal Tube in EBUS-TBNA Procedure Under Moderate Sedation
ClinicalTrials.gov ID: NCT06799455
Acronym / sponsor ID: PACCS-2024-33033
Conditions: Multiple Pulmonary Diseases
Study type: Interventional
Recruitment status: TerminatedReason stopped: We are closing due to a change in practice here that means we are no longer seeing eligible participants
Enrolment: 4 participants (actual)
Lead sponsor: University of MinnesotaUniversity, hospital or other
Study start: 2 Jun 2025 (actual)
Primary completion: 10 Jun 2026 (actual)
Study completion: 10 Jun 2026 (actual)
First posted: 29 Jan 2025 (actual)
Results: Posted 22 Sep 2026

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Study design

Primary purpose: Health services research
Allocation: Not applicable
Intervention model: Parallel groups
Masking: None (open label)
Number of arms: 2
Model description: Patient will be randomized 1:1 to UCETT vs no ETT (current standard procedure) when they scheduled for the EBUS-TBNA procedure.

Arm	Type	Receives
uncuffed endotracheal group	Experimental	Device: Endotracheal tube
no endotracheal tube group/control	No intervention	–

Who may qualify

Ages: 18 years and older
Sex: All
Healthy volunteers: Not accepted
Age groups: Adult, Older adult

Key inclusion criteria (1 listed)

Any patient that is scheduled for EBUS-TBNA procedure

Key exclusion criteria (1 listed)

Those who are not safe to receive moderate sedation or flexible bronchoscopy

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
Endotracheal tubeparticipants either receive the ETT during the procedure	Device	uncuffed endotracheal group

Primary outcome

Desaturation
Time frame: During the procedure
Whether a patient will experience any desaturation

Results and safety

Results posted to the registry on 22 Sep 2026, as reported by the sponsor. Figures are copied from the record, not re-analysed. Full results on ClinicalTrials.gov.

Participant flow

Group	Started	Completed
Uncuffed Endotracheal Group	1	1
no Endotracheal Tube Group/Control	3	3

Primary outcome: Desaturation

Time frame: During the procedure. Count of participants. Unit: Participants

Measure	Uncuffed Endotracheal Group n = 1	no Endotracheal Tube Group/Control n = 3
Value	0	0

Population analysed: The study was closed early because of a change in practice at the site, resulting in only 4 enrolled participants. Desaturation outcomes were assessed for all enrolled participants: 1 participant in the uncuffed endotracheal tube group and 3 participants in the no endotracheal tube/control group.

Adverse events

Time frame: From enrollment through completion of the EBUS-TBNA procedure and post-procedure recovery, up to 1 day.. Other adverse events reported at 0% frequency or more

Group	Serious adverse events	Other adverse events	Deaths
Uncuffed Endotracheal Group	0 of 1 (0%)	0 of 1 (0%)	0 of 1
no Endotracheal Tube Group/Control	0 of 3 (0%)	0 of 3 (0%)	0 of 3

Limitations and caveats (from the sponsor): The study was closed due to a change in practice, that resulted in no longer seeing eligible participants.

Loading the posted results from ClinicalTrials.gov…

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 22 Sep 2026.
Posted resultsParticipant flow, baseline, all outcome measures and adverse events.

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Active, not recruitingPhase 2
Safety, Preliminary Effectiveness of BNT327, an Investigational Therapy for Patients With Small-cell Lung Cancer in Combination With Chemotherapy
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Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

H. Erhan Dincer principal investigator

University of Minnesota

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing Endotracheal tube in people with Multiple Pulmonary Diseases, run by University of Minnesota at 1 site in United States.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: stopped early, as of the sponsor's last update on 22 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

Yes. Results are posted in the registry (first posted 22 Sep 2026). A summary is in the For doctors view, and the full results are on ClinicalTrials.gov.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Desaturation (time frame: During the procedure). It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT06799455.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Sep 2026.