AnxietyNCT06825000
Scientific Information and Beliefs About Psychological Therapy
A study testing neuro-education and psycho-education in people with Anxiety, run by University of California, Irvine at 1 site in United States.
Trial summary
The success of psychological therapy can be impacted by patients' beliefs, such as their belief in their own ability to complete therapy and their belief that therapy will work. The goal of this clinical trial is to learn whether and when scientific information about distress and coping can affect beliefs about… Read more about this study
- Who is it for?
- Ages 18 to 80 years
- Conditions the study is for
- Anxiety
- What is being tested?
- neuro-education and psycho-education
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 262 participants
- Where
- 1 siteUnited States
- Study dates
- 21 May 2025to 17 Oct 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 80 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Probable anxiety disorder based on the Overall Anxiety Severity and Impairment Scale (OASIS) score
- Fluent in English
- Willingness and ability to comply with the protocol
- Age 18-80
- The ability to enroll in the study through Prolific.com
Who cannot join
- Having previously seen the study's videos
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Effects of Science Education on Beliefs and Wellness
The success of psychological therapy can be impacted by patients' beliefs, such as their belief in their own ability to complete therapy and their belief that therapy will work. The goal of this clinical trial is to learn whether and when scientific information about distress and coping can affect beliefs about psychological therapy in adults who experience anxiety. This study will compare two different types of scientific information in a one-hour study. Participants will view educational videos for 30 minutes and complete surveys, including quiz questions about the videos and surveys about their beliefs about psychological therapy.
- Conditions
- Anxiety
- Being tested
- neuro-education, psycho-education
- Keywords
- beliefs, mindsets, exposure therapy, neuroscience education, psycho-education, neuro-education
- Medical subject headings
- Anxiety Disorders
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
neuro-educationBehavioural
Also called neuroscience education, Neuro-Ed, NeuroEd
30 minutes of videos about the neuroscience of stress, fear, emotion-regulation, and therapy.
psycho-educationBehavioural
30 minutes of videos about the psychological science of stress, fear, emotion-regulation, and therapy.
| Study group | Role | What they receive |
|---|---|---|
| Neuro-Ed Group | Experimental | neuroscience education Receives: Behavioral: neuro-education |
| Psycho-Ed Group | Active comparator | psychological science education Receives: Behavioral: psycho-education |
What is being measured
The primary outcome is the main question the study is designed to answer.
Treatment Self-Efficacy
Measured through self-report on selected items from a version of the validated Bergen Genetic Counseling Self-Efficacy Scale that was previously adapted for treatment self-efficacy in anxiety disorders. The items are rated on a scale of 1-10, with higher numbers indicating greater self-efficacy.
Measured: Immediately before and immediately after watching the videos
Treatment Expectancy
Measured through self-report on a subscale of the validated Credibility/Expectancy Questionnaire, assessing participants' expectation of treatment efficacy. Each item is rated on a scale of 1-9 or 0%-100%, with higher numbers indicating more optimistic expectancy.
Measured: Immediately before and immediately after watching the videos
Secondary outcomes (1)
Treatment Acceptability
Participants will rate on a scale of 1-7 how useful, interesting, credible, and easy-to-understand they found the information in the videos. Greater numbers indicate greater acceptability.
Measured: Immediately after watching the videos
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Feb 2025
- Study start21 May 2025
- Primary completion9 Oct 2025
- Study completion17 Oct 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for AnxietyStudies of the same condition, open and under way.
- More trials run by University of California, IrvineThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 262 participants (actual)
Sponsor and investigators
- Lead sponsor
- University of California, Irvine
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Golnaz Tabibnia, University of California, Irvine
- Investigators
- Golnaz Tabibnia, PhD, Principal investigator, University of California, Irvine
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06825000
- Sponsor's protocol ID
- 3274
- Status last verified
- Apr 2026
- First submitted
- 23 Jan 2025
- Last updated
- 14 Apr 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: De-identified IPD that underlie results in a publication may be provided to qualified researchers with academic interest in science education and mental health. Approval of the request and execution of all applicable agreements may be prerequisites to the sharing of data with the requesting party.
Study at a glance
From the registry record, last updated by the sponsor on 14 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effects of Science Education on Beliefs and Wellness
- ClinicalTrials.gov ID
- NCT06825000
- Acronym / sponsor ID
- 3274
- Conditions
- Anxiety
- Keywords
- beliefs, mindsets, exposure therapy, neuroscience education, psycho-education, neuro-education
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 262 participants (actual)
- Lead sponsor
- University of California, IrvineUniversity, hospital or other
- Study start
- 21 May 2025 (actual)
- Primary completion
- 9 Oct 2025 (actual)
- Study completion
- 17 Oct 2025 (actual)
- First posted
- 13 Feb 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The success of psychological therapy can be impacted by patients' beliefs, such as their belief in their own ability to complete therapy and their belief that therapy will work. The goal of this clinical trial is to learn whether and when scientific information about distress and coping can affect beliefs about psychological therapy in adults who experience anxiety. This study will compare two different types of scientific information in a one-hour study. Participants will view educational videos for 30 minutes and complete surveys, including quiz questions about the videos and surveys about their beliefs about psychological therapy.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Neuro-Ed Group | Experimental | Behavioral: neuro-educationneuroscience education |
| Psycho-Ed Group | Active comparator | Behavioral: psycho-educationpsychological science education |
Who may qualify
- Ages
- 18 to 80 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (5 listed)
- Probable anxiety disorder based on the Overall Anxiety Severity and Impairment Scale (OASIS) score
- Fluent in English
- Willingness and ability to comply with the protocol
- Age 18-80
- The ability to enroll in the study through Prolific.com
Key exclusion criteria (1 listed)
- Having previously seen the study's videos
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| neuro-educationAlso: neuroscience education, Neuro-Ed, NeuroEd30 minutes of videos about the neuroscience of stress, fear, emotion-regulation, and therapy. | Behavioural | Neuro-Ed Group |
| psycho-education30 minutes of videos about the psychological science of stress, fear, emotion-regulation, and therapy. | Behavioural | Psycho-Ed Group |
Primary outcome
Treatment Self-Efficacy
Time frame: Immediately before and immediately after watching the videos
Measured through self-report on selected items from a version of the validated Bergen Genetic Counseling Self-Efficacy Scale that was previously adapted for treatment self-efficacy in anxiety disorders. The items are rated on a scale of 1-10, with higher numbers indicating greater self-efficacy.
Treatment Expectancy
Time frame: Immediately before and immediately after watching the videos
Measured through self-report on a subscale of the validated Credibility/Expectancy Questionnaire, assessing participants' expectation of treatment efficacy. Each item is rated on a scale of 1-9 or 0%-100%, with higher numbers indicating more optimistic expectancy.
1 secondary outcome
Treatment Acceptability
Time frame: Immediately after watching the videos
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 14 Apr 2026.
- Individual participant dataSharing planned: Yes. De-identified IPD that underlie results in a publication may be provided to qualified researchers with academic interest in science education and mental health. Approval of the request and execution of all applicable agreements may be prerequisites to the sharing of data with the requesting party.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Golnaz Tabibnia, PhD principal investigator
University of California, Irvine
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing neuro-education and psycho-education in people with Anxiety, run by University of California, Irvine at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 14 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Treatment Self-Efficacy (time frame: Immediately before and immediately after watching the videos). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Apr 2026.