CyclistsNCT06827574

Comparative Effects of Sciatic Nerve Flossing and Active Release Technique in Cyclists With Sciatica

A study testing Sciatic nerve flossing technique and Active Release Technique in people with Cyclists and Sciatica, run by Riphah International University at 1 site in Pakistan.

Active, not recruiting

Under way, not looking for participants. Everyone needed has enrolled. The study is still running.

Official record

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Trial summary

Thus the aim of my study is to determine the comparative effects of sciatic nerve flossing and active release technique on pain, flexibility, and functionality in lower limbs of cyclists with sciatica. Read more about this study

Who is it for?: Ages 18 to 30 years, men onlyHealthy volunteers can take part
Conditions the study is for: Cyclists, Sciatica
What is being tested?: Sciatic nerve flossing technique and Active Release Technique
Could I receive a placebo?: No, everyone receives an active treatment
How many people: 32 participants
Where: 1 sitePakistan
Study dates: 24 Apr 2024to 15 Feb 2025
Phase: Interventional
Are there results?: Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

Ages 18 to 30 years
Men only
Healthy volunteers accepted
Adult

Who may be able to join

Age between 18 to 30 years (16)
Only male participants were included (15)
Participates with Positive Passive Straight Leg Raise (PSLR) Test (13)
Athletes with positive slump test (15)
Symptoms more than 6 weeks (16)

Who cannot join

Lower limb fracture(13)
Musculoskeletal problems (radiculopathy, myopathy) (13, 14)
Sciatica along with vascular disorders and diabetic neuropathy, sciatica due to tumor and fractures (15)
Inflammatory arthritis (16)
Previous surgical interventions on the lower limbs or spine (15)
Neurological conditions affecting lower limb function (e.g., multiple sclerosis, spinal cord injuries) (13, 14)
Patients currently undergoing physical therapy or other interventions for sciatica (15)
Individuals with contraindications to physical activity or exercise due to health conditions (13, 14)

Trial locations and contacts

1 site in 1 country.

Pakistan1 site

University of Lahore
Lahore, Punjab Province

Other trials in Pakistan

About this study

Official title: Comparative Effects of Sciatic Nerve Flossing and Active Release Technique on Pain, Flexibility and Functionality in Lower Limbs Among Cyclists With Sciatica

Read the detailed description

This study investigates the comparative effects of Sciatic Nerve Flossing and Active Release Technique on pain, flexibility, and functionality in cyclists with sciatica. To compare the efficacy of Sciatic Nerve Flossing and Active Release Technique in reducing pain and improving functional performance in cyclists diagnosed with sciatica over a six-week period. A randomized clinical trial was conducted with 32 participants, aged 18 to 35, diagnosed with sciatica persisting for more than six weeks. Participants were randomly assigned to two groups: Group A received Sciatic Nerve Flossing, while Group B underwent Active Release Technique. Pain levels were measured using the Numeric Pain Rating Scale (NPRS), functional performance was assessed using the Lower Extremity Functional Score (LEFS), and flexibility was evaluated via the Sit and Reach Test.

Conditions: Cyclists, Sciatica
Being tested: Sciatic nerve flossing technique, Active Release Technique
Keywords: Active release technique, cyclists, functional performance, pain management, sciatica, sciatic nerve flossing technique
Medical subject headings: Sciatica, Agnosia

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

Sciatic nerve flossing techniqueOther
Group A 16 subjects were treated with Sciatic Nerve Flossing Technique. Subjects were in sitting position. Nerve Flossing Technique was performed actively with the participant sitting on a chair. The participant was flex the knee of the target lower extremity backwards beside the chair, as far back as possible and flex the neck at the same time, holding both the flexed knee and neck in this position for 10 seconds. The participant in turn will extend the neck and the knee of the target lower extremity, abduct and then flex the hip until pain is felt and do not push beyond that point. This extended position was maintained for 10 seconds. The above procedure of Nerve Flossing Technique was repeated for 15 times, 3 sets with an interval of 5 minutes between each set. As the nerve becomes less sensitive, the participant can increase the stretching effect by dorsiflexion the ankle and extending the toes of the foot upward towards the shin.
Active Release TechniqueOther
Group B 16 subjects were treated with Active Release Technique. Subjects were in prone position. ART was performed actively by the participant lying on a bed. The participant was dorsiflex the foot of the target lower extremity, holding the dorsiflexion foot in this position for 10 seconds. The participant in turn was plantar-flexed the foot of the target lower extremity. This dorsiflexion position was maintained for 10 seconds. The above procedure of Active Release Technique was repeated for 15 times, 3 sets with an interval of 5 minutes between each set. As the muscles becomes more flexible, the participant can increase the flexibility effect by plantar flexing the foot.

Study groups in NCT06827574
Study group	Role	What they receive
Sciatic nerve flossing technique	Experimental	Group A 16 subjects were treated with Sciatic Nerve Flossing Technique. Receives: Other: Sciatic nerve flossing technique
Active Release Technique	Active comparator	Group B 16 subjects were treated with Active Release Technique Receives: Other: Active Release Technique

What is being measured

The primary outcome is the main question the study is designed to answer.

NPRS
The Numeric Aggravation Rating Scale (NPRS) is normally used to survey torment. Change in the NPRS across time can be deciphered with responsiveness lists. Patient level of pain will be assessed using this scale. This scale ranges from 0 to 10. 0 indicates "no pain" and 10 indicates "worst pain(48). High test-retest reliability is indicated by an ICC > 0.70; Cronbach's alpha > 0.70 suggests great internal consistency. The construct validity of the NPRS examines how well the scores correspond to theoretical pain components, while the criterion validity compares results to established pain measures.(49).
Measured: 6 Weeks
Sit and Reach Test
Sit-and-arrive at tests are generally utilized as estimation apparatuses for assessing hamstring and lower back adaptability. The old style sits and arrive at test (SRT), initially planned by Wells and Dillon (1952) is frequently included as a feature of game related actual wellness test batteries (American Union for Wellbeing Actual Instruction Entertainment and Dance (AAHPERD), 1986, Gathering of Europe Council for the Improvement of Game, 1993) to assess hamstring muscle adaptability. The SRT and TT test have a similar testing strategy (maximal trunk flexion with knee straight and lower leg in 90° of dorsiflexion) with the main contrast being the trying position, sitting and standing, separately(50).
Measured: 6 weeks
Lower Extremity Funtional Score
The reasonable structure that directed the improvement of the LEFS incorporated that the scale be founded on the World Wellbeing Association's model of incapacity and impairment, be effective to manage, score, and record in the clinical record as for patient and clinician time, be pertinent to a wide assortment of patients with lower-limit muscular circumstances, incorporating patients with a scope of handicap levels, conditions, illnesses, medicines, and ages, be material for reporting capability on a singular patient premise as well as in gatherings, for example, for clinical results evaluation and clinical examination designs, be created utilizing an efficient course of thing determination and thing scaling, yield solid estimations (have inner consistency and test-retest dependability), and yield substantial estimations (at a solitary moment and delicate to legitimate change)(51)(52). While ICC > 0.70 indicates good reliability for LEFS, Cronbach's alpha > 0.70 ensures internal con
Measured: 6 weeks

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

24 Apr 202415 Feb 2025

First posted14 Feb 2025
Study start24 Apr 2024
Primary completion10 Feb 2025 (estimated)
Study completion15 Feb 2025 (estimated)

Resources

Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
Publications (10)Papers the sponsor has linked to this study.
Other trials for CyclistsStudies of the same condition, open and under way.
What the trial phases meanHow a treatment moves from first tests in people to approval.

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design

Study type: Interventional
Phase: Phase N/A
Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: Single blind
Who is masked: Outcomes assessor
Enrolment: 32 participants (actual)

IDs, dates and publications

ClinicalTrials.gov ID: NCT06827574
Sponsor's protocol ID: REC/RCR&AHS/24/0404
Status last verified: Feb 2025
First submitted: 10 Feb 2025
Last updated: 14 Feb 2025
Results posted: No
Data monitoring committee: Yes
FDA-regulated drug: No
FDA-regulated device: No
Individual data sharing: No

Publications

Chiaramonte R, Pavone P, Vecchio M. Diagnosis, Rehabilitation and Preventive Strategies for Pudendal Neuropathy in Cyclists, A Systematic Review. J Funct Morphol Kinesiol. 2021 May 10;6(2):42. doi: 10.3390/jfmk6020042.
PubMed 34068471
Battista S, Sansone LG, Testa M. Prevalence, Characteristics, Association Factors of and Management Strategies for Low Back Pain Among Italian Amateur Cyclists: an Observational Cross-Sectional Study. Sports Med Open. 2021 Oct 28;7(1):78. doi: 10.1186/s40798-021-00370-2.
PubMed 34709475
Zhang YH, Hu HY, Xiong YC, Peng C, Hu L, Kong YZ, Wang YL, Guo JB, Bi S, Li TS, Ao LJ, Wang CH, Bai YL, Fang L, Ma C, Liao LR, Liu H, Zhu Y, Zhang ZJ, Liu CL, Fang GE, Wang XQ. Exercise for Neuropathic Pain: A Systematic Review and Expert Consensus. Front Med (Lausanne). 2021 Nov 24;8:756940. doi: 10.3389/fmed.2021.756940. eCollection 2021.
PubMed 34901069
Chang TT, Li Z, Zhu YC, Wang XQ, Zhang ZJ. Effects of Self-Myofascial Release Using a Foam Roller on the Stiffness of the Gastrocnemius-Achilles Tendon Complex and Ankle Dorsiflexion Range of Motion. Front Physiol. 2021 Sep 17;12:718827. doi: 10.3389/fphys.2021.718827. eCollection 2021.
PubMed 34603078
Mehta SP, Fulton A, Quach C, Thistle M, Toledo C, Evans NA. Measurement Properties of the Lower Extremity Functional Scale: A Systematic Review. J Orthop Sports Phys Ther. 2016 Mar;46(3):200-16. doi: 10.2519/jospt.2016.6165. Epub 2016 Jan 26.
PubMed 26813750
Dingemans SA, Kleipool SC, Mulders MAM, Winkelhagen J, Schep NWL, Goslings JC, Schepers T. Normative data for the lower extremity functional scale (LEFS). Acta Orthop. 2017 Aug;88(4):422-426. doi: 10.1080/17453674.2017.1309886. Epub 2017 Mar 28.
PubMed 28350206
Michener LA, Snyder AR, Leggin BG. Responsiveness of the numeric pain rating scale in patients with shoulder pain and the effect of surgical status. J Sport Rehabil. 2011 Feb;20(1):115-28. doi: 10.1123/jsr.20.1.115.
PubMed 21411827
Danazumi MS, Nuhu JM, Ibrahim SU, Falke MA, Rufai SA, Abdu UG, Adamu IA, Usman MH, Daniel Frederic A, Yakasai AM. Effects of spinal manipulation or mobilization as an adjunct to neurodynamic mobilization for lumbar disc herniation with radiculopathy: a randomized clinical trial. J Man Manip Ther. 2023 Dec;31(6):408-420. doi: 10.1080/10669817.2023.2192975. Epub 2023 Mar 22.
PubMed 36950742
Ashbrook J, Rogdakis N, Callaghan MJ, Yeowell G, Goodwin PC. The therapeutic management of back pain with and without sciatica in the emergency department: a systematic review. Physiotherapy. 2020 Dec;109:13-32. doi: 10.1016/j.physio.2020.07.005. Epub 2020 Jul 23.
PubMed 32846282
Albert HB, Manniche C. The efficacy of systematic active conservative treatment for patients with severe sciatica: a single-blind, randomized, clinical, controlled trial. Spine (Phila Pa 1976). 2012 Apr 1;37(7):531-42. doi: 10.1097/BRS.0b013e31821ace7f.
PubMed 21494193

Want to know more?

The sponsor has not listed a contact. The official record may have more details.

Talk to your doctor first and take this page with you. Only the study team can confirm whether you can join.

Questions to ask the study team

What is the study trying to find out?
What would I need to do, and how often would I visit?
Could I receive a placebo instead of the treatment?
What are the possible risks and benefits for me?
Will it cost me anything? Are travel or time paid for?
Can I keep seeing my own doctor during the study?
What happens when the study ends?

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All Cyclists trials

Study at a glance

From the registry record, last updated by the sponsor on 14 Feb 2025. Recruitment status is as the sponsor reported it: confirm with the study team.

Official title: Comparative Effects of Sciatic Nerve Flossing and Active Release Technique on Pain, Flexibility and Functionality in Lower Limbs Among Cyclists With Sciatica
ClinicalTrials.gov ID: NCT06827574
Acronym / sponsor ID: REC/RCR&AHS/24/0404
Conditions: Cyclists, Sciatica
Keywords: Active release technique, cyclists, functional performance, pain management, sciatica, sciatic nerve flossing technique
Study type: Interventional
Recruitment status: Active, not recruiting
Enrolment: 32 participants (actual)
Lead sponsor: Riphah International UniversityUniversity, hospital or other
Study start: 24 Apr 2024 (actual)
Primary completion: 10 Feb 2025 (estimated)
Study completion: 15 Feb 2025 (estimated)
First posted: 14 Feb 2025 (actual)
Results: Not posted in the source record

Clinical summary

The research question as the sponsor registered it. This describes what the study plans to test, not what it found.

Detailed description

Study design

Primary purpose: Treatment
Allocation: Randomised
Intervention model: Parallel groups
Masking: Single blind (outcomes assessor)
Number of arms: 2

Arm	Type	Receives
Sciatic nerve flossing technique	Experimental	Other: Sciatic nerve flossing techniqueGroup A 16 subjects were treated with Sciatic Nerve Flossing Technique.
Active Release Technique	Active comparator	Other: Active Release TechniqueGroup B 16 subjects were treated with Active Release Technique

Who may qualify

Ages: 18 to 30 years
Sex: Male only
Healthy volunteers: Accepted
Age groups: Adult

Key inclusion criteria (5 listed)

Age between 18 to 30 years (16)
Only male participants were included (15)
Participates with Positive Passive Straight Leg Raise (PSLR) Test (13)
Athletes with positive slump test (15)
Symptoms more than 6 weeks (16)

Key exclusion criteria (8 listed)

Lower limb fracture(13)
Musculoskeletal problems (radiculopathy, myopathy) (13, 14)
Sciatica along with vascular disorders and diabetic neuropathy, sciatica due to tumor and fractures (15)
Inflammatory arthritis (16)
Previous surgical interventions on the lower limbs or spine (15)

Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.

Interventions

Intervention	Type	Arms
Sciatic nerve flossing techniqueGroup A 16 subjects were treated with Sciatic Nerve Flossing Technique. Subjects were in sitting position. Nerve Flossing Technique was performed actively with the participant sitting on a chair. The participant was flex the knee of the target lower extremity backwards beside the chair, as far back as possible and flex the neck at the same time, holding both the flexed knee and neck in this position for 10 seconds. The participant in turn will extend the neck and the knee of the target lower extremity, abduct and then flex the hip until pain is felt and do not push beyond that point. This extended position was maintained for 10 seconds. The above procedure of Nerve Flossing Technique was repeated for 15 times, 3 sets with an interval of 5 minutes between each set. As the nerve becomes less sensitive, the participant can increase the stretching effect by dorsiflexion the ankle and extending the toes of the foot upward towards the shin.	Other	Sciatic nerve flossing technique
Active Release TechniqueGroup B 16 subjects were treated with Active Release Technique. Subjects were in prone position. ART was performed actively by the participant lying on a bed. The participant was dorsiflex the foot of the target lower extremity, holding the dorsiflexion foot in this position for 10 seconds. The participant in turn was plantar-flexed the foot of the target lower extremity. This dorsiflexion position was maintained for 10 seconds. The above procedure of Active Release Technique was repeated for 15 times, 3 sets with an interval of 5 minutes between each set. As the muscles becomes more flexible, the participant can increase the flexibility effect by plantar flexing the foot.	Other	Active Release Technique

Primary outcome

NPRS
Time frame: 6 Weeks
The Numeric Aggravation Rating Scale (NPRS) is normally used to survey torment. Change in the NPRS across time can be deciphered with responsiveness lists. Patient level of pain will be assessed using this scale. This scale ranges from 0 to 10. 0 indicates "no pain" and 10 indicates "worst pain(48). High test-retest reliability is indicated by an ICC > 0.70; Cronbach's alpha > 0.70 suggests great internal consistency. The construct validity of the NPRS examines how well the scores correspond to theoretical pain components, while the criterion validity compares results to established pain measures.(49).
Sit and Reach Test
Time frame: 6 weeks
Sit-and-arrive at tests are generally utilized as estimation apparatuses for assessing hamstring and lower back adaptability. The old style sits and arrive at test (SRT), initially planned by Wells and Dillon (1952) is frequently included as a feature of game related actual wellness test batteries (American Union for Wellbeing Actual Instruction Entertainment and Dance (AAHPERD), 1986, Gathering of Europe Council for the Improvement of Game, 1993) to assess hamstring muscle adaptability. The SRT and TT test have a similar testing strategy (maximal trunk flexion with knee straight and lower leg in 90° of dorsiflexion) with the main contrast being the trying position, sitting and standing, separately(50).
Lower Extremity Funtional Score
Time frame: 6 weeks
The reasonable structure that directed the improvement of the LEFS incorporated that the scale be founded on the World Wellbeing Association's model of incapacity and impairment, be effective to manage, score, and record in the clinical record as for patient and clinician time, be pertinent to a wide assortment of patients with lower-limit muscular circumstances, incorporating patients with a scope of handicap levels, conditions, illnesses, medicines, and ages, be material for reporting capability on a singular patient premise as well as in gatherings, for example, for clinical results evaluation and clinical examination designs, be created utilizing an efficient course of thing determination and thing scaling, yield solid estimations (have inner consistency and test-retest dependability), and yield substantial estimations (at a solitary moment and delicate to legitimate change)(51)(52). While ICC > 0.70 indicates good reliability for LEFS, Cronbach's alpha > 0.70 ensures internal con

Results and safety

This study is still under way. Results are not available in the source record yet.

Research links

Official record on ClinicalTrials.govLast updated by the sponsor 14 Feb 2025.
Background: PubMed 34068471Chiaramonte R, Pavone P, Vecchio M. Diagnosis, Rehabilitation and Preventive Strategies for Pudendal Neuropathy in Cyclists, A Systematic Review. J Funct Morphol Kinesiol. 2021 May 10;6(2):42. doi: 10.3390/jfmk6020042.
Background: PubMed 34709475Battista S, Sansone LG, Testa M. Prevalence, Characteristics, Association Factors of and Management Strategies for Low Back Pain Among Italian Amateur Cyclists: an Observational Cross-Sectional Study. Sports Med Open. 2021 Oct 28;7(1):78. doi: 10.1186/s40798-021-00370-2.
Background: PubMed 34901069Zhang YH, Hu HY, Xiong YC, Peng C, Hu L, Kong YZ, Wang YL, Guo JB, Bi S, Li TS, Ao LJ, Wang CH, Bai YL, Fang L, Ma C, Liao LR, Liu H, Zhu Y, Zhang ZJ, Liu CL, Fang GE, Wang XQ. Exercise for Neuropathic Pain: A Systematic Review and Expert Consensus. Front Med (Lausanne). 2021 Nov 24;8:756940. doi: 10.3389/fmed.2021.756940. eCollection 2021.
Background: PubMed 34603078Chang TT, Li Z, Zhu YC, Wang XQ, Zhang ZJ. Effects of Self-Myofascial Release Using a Foam Roller on the Stiffness of the Gastrocnemius-Achilles Tendon Complex and Ankle Dorsiflexion Range of Motion. Front Physiol. 2021 Sep 17;12:718827. doi: 10.3389/fphys.2021.718827. eCollection 2021.
Background: PubMed 26813750Mehta SP, Fulton A, Quach C, Thistle M, Toledo C, Evans NA. Measurement Properties of the Lower Extremity Functional Scale: A Systematic Review. J Orthop Sports Phys Ther. 2016 Mar;46(3):200-16. doi: 10.2519/jospt.2016.6165. Epub 2016 Jan 26.
Background: PubMed 28350206Dingemans SA, Kleipool SC, Mulders MAM, Winkelhagen J, Schep NWL, Goslings JC, Schepers T. Normative data for the lower extremity functional scale (LEFS). Acta Orthop. 2017 Aug;88(4):422-426. doi: 10.1080/17453674.2017.1309886. Epub 2017 Mar 28.
Background: PubMed 21411827Michener LA, Snyder AR, Leggin BG. Responsiveness of the numeric pain rating scale in patients with shoulder pain and the effect of surgical status. J Sport Rehabil. 2011 Feb;20(1):115-28. doi: 10.1123/jsr.20.1.115.
Background: PubMed 36950742Danazumi MS, Nuhu JM, Ibrahim SU, Falke MA, Rufai SA, Abdu UG, Adamu IA, Usman MH, Daniel Frederic A, Yakasai AM. Effects of spinal manipulation or mobilization as an adjunct to neurodynamic mobilization for lumbar disc herniation with radiculopathy: a randomized clinical trial. J Man Manip Ther. 2023 Dec;31(6):408-420. doi: 10.1080/10669817.2023.2192975. Epub 2023 Mar 22.
Background: PubMed 32846282Ashbrook J, Rogdakis N, Callaghan MJ, Yeowell G, Goodwin PC. The therapeutic management of back pain with and without sciatica in the emergency department: a systematic review. Physiotherapy. 2020 Dec;109:13-32. doi: 10.1016/j.physio.2020.07.005. Epub 2020 Jul 23.
Background: PubMed 21494193Albert HB, Manniche C. The efficacy of systematic active conservative treatment for patients with severe sciatica: a single-blind, randomized, clinical, controlled trial. Spine (Phila Pa 1976). 2012 Apr 1;37(7):531-42. doi: 10.1097/BRS.0b013e31821ace7f.
Individual participant dataSharing planned: No

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Referral and contact

AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.

Farwa Imtiaz Ahmad, DPT principal investigator

Riphah International University

1 site in 1 country: see every site and its status.

Questions about this trial

What is this clinical trial studying?

A study testing Sciatic nerve flossing technique and Active Release Technique in people with Cyclists and Sciatica, run by Riphah International University at 1 site in Pakistan.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 5 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: under way, not looking for participants, as of the sponsor's last update on 14 Feb 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

NPRS (time frame: 6 Weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT06827574, which also lists 10 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 14 Feb 2025.