Anterior Cruciate Ligament Reconstruction RehabilitationDUACLNCT06845150
Combined Compared to Sequential Cognitive and Physical Training in Anterior Cruciate Ligament Reconstructed Individuals
A study testing Dual-task training and Single task training in people with Anterior Cruciate Ligament Reconstruction Rehabilitation, run by Michelle C. Haas at 2 sites in Switzerland.
Trial summary
The goal of this clinical trial is to investigate changes in cognitive and physical performance after 10 weeks of dual or single task training in anterior cruciate ligament (ACL) reconstructed individuals. Read more about this study
- Who is it for?
- Ages 18 to 40 years
- Conditions the study is for
- Anterior Cruciate Ligament Reconstruction Rehabilitation
- What is being tested?
- Dual-task training and Single task training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 2 participants
- Where
- 2 sitesSwitzerland
- Study dates
- 5 Jun 2025to 8 Oct 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 40 years
- All sexes
- No healthy volunteers
- Adult
Who may be able to join
- 18-40 years old
- At least 6 months after ACL injury
- Surgically reconstructed ACL
- At least 2 hours of sports participation before the injury
- Written consent of the attending surgeon to perform intensified training methods including one-legged jumps at 6 months after surgery after the first visit
- Ability to give informed consent as documented by signature
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- Ability to understand instructions in German or English
- BMI < 28 kg/m^2
- Availability to take part in at least 70% of all training sessions
Who cannot join
- Surgery on the contralateral leg during the last 12 months
- Acute or chronic musculoskeletal, neurological, or cardiopulmonary disorders
- Unadjusted vision problems
- Concussion during the last 6 months
- Pregnancy
- Breastfeeding
- Amputation
- Inflammatory pain or swelling during exercising
Trial locations and contacts
2 sites in 1 country.
Switzerland2 sites
KSW Kantonsspital Winterthur
Winterthur, 8000
ZHAW Zurich University of Applied Sciences
Winterthur, 8000
About this study
Official title: Dual-Task Training in an Immersive Environment Compared to Single Task Training in Anterior Cruciate Ligament Reconstructed Individuals
The goal of this clinical trial is to investigate changes in cognitive and physical performance after 10 weeks of dual or single task training in anterior cruciate ligament (ACL) reconstructed individuals. The main questions it aims to answer are:
- Does cognitive performance in ACL reconstructed individuals change after multiple training sessions incorporating single versus dual-task?
- Does physical performance and intrinsic motivation for training change over the course of 10 weeks when performing single versus dual-task training sessions?
- What movement patterns do ACL reconstructed individuals show during a dual-task training in an immersive environment?
Read more
Researchers will compare a combined dual-task training (combined physical and cognitive training) to a single task training (physical and cognitive training separately) to see if there are changes on cognitive performance depending on the training type.
Participants will:
- Perform dual-task or single task training twice per week for 10 weeks
- Visit the clinic before and after the training period for tests
- Visit the movement laboratory once for analysis of movement patterns
- Being tested
- Dual-task training, Single task training
- Keywords
- motor-cognitive training, dual-task training, anterior cruciate ligament injury, return to competition
- Medical subject headings
- Anterior Cruciate Ligament Injuries
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Dual-task trainingOther
Combined simultaneous physical and cognitive training in an immersive environment
Single task trainingOther
Sequential cognitive and then physical training
| Study group | Role | What they receive |
|---|---|---|
| Dual-task training | Experimental | Not described Receives: Other: Dual-task training |
| Single task training | Active comparator | Not described Receives: Other: Single task training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Interference
Measured by the difference in reaction time of congruent and incongruent stimuli of the Flanker task.
Measured: Baseline, after 5 weeks of training, after 10 weeks of training
Response inhibition
Measured by the accuracy of Go/No-Go-stimuli
Measured: Baseline, after 5 weeks of training, after 10 weeks of training
Secondary outcomes (6)
Jumping performance - contact time
Contact time during jumping on force plates.
Measured: Baseline and after 10 weeks of training
Jumping performance - peak force
Peak force during jumping on force plates.
Measured: Baseline and after 10 weeks of training
Strength
Peak force of hamstring, quadriceps, hip abduction, and hip adduction
Measured: Baseline and after 10 weeks of training
Intrinsic motivation
German version of the short scale for intrinsic motivation (Kurzskala Intrinsische Motivation). For each of the 12 items there is a 5-point Likert-Scale resulting in values of 0-4. Therefore, the total score ranges from 0 to 48. The higher the score, the higher the intrinsic motivation.
Measured: At the end of each training session (2x/week for 10 weeks)
Kinematics and kinetics of the lower extremities
Hip, knee, and ankle angles and moments and ground reaction forces
Measured: During dual-task training in an immersive environment
Kinematics and kinetics of the lower extremities
Ground reaction forces, angles and moments of hip, knee, and ankle during functional tasks
Measured: Baseline and after 10 weeks of training
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Feb 2025
- Study start5 Jun 2025
- Primary completion12 Jun 2025
- Study completion8 Oct 2025
Why it stopped: Insufficient recruitment rate to reach the targeted number in June 2026
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Anterior Cruciate Ligament Reconstruction RehabilitationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 2 participants (actual)
Sponsor and investigators
- Lead sponsor
- Michelle C. Haas
- Sponsor type
- University, hospital or other
- Collaborators
- Kantonsspital Winterthur KSW, ZHAW DIZH Fellowship Program
- Responsible party
- Sponsor-investigator, Michelle C. Haas, Zurich University of Applied Sciences
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06845150
- Sponsor's protocol ID
- DUACL
- Acronym
- DUACL
- Status last verified
- Dec 2025
- First submitted
- 13 Feb 2025
- Last updated
- 8 Dec 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Individual participant data will be shared if ethically and legally possible.
Study at a glance
From the registry record, last updated by the sponsor on 8 Dec 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Dual-Task Training in an Immersive Environment Compared to Single Task Training in Anterior Cruciate Ligament Reconstructed Individuals
- ClinicalTrials.gov ID
- NCT06845150
- Acronym / sponsor ID
- DUACL / DUACL
- Keywords
- motor-cognitive training, dual-task training, anterior cruciate ligament injury, return to competition
- Study type
- Interventional
- Recruitment status
- TerminatedReason stopped: Insufficient recruitment rate to reach the targeted number in June 2026
- Enrolment
- 2 participants (actual)
- Lead sponsor
- Michelle C. HaasUniversity, hospital or other
- Collaborators
- Kantonsspital Winterthur KSW, ZHAW DIZH Fellowship Program
- Study start
- 5 Jun 2025 (actual)
- Primary completion
- 12 Jun 2025 (actual)
- Study completion
- 8 Oct 2025 (actual)
- First posted
- 25 Feb 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The goal of this clinical trial is to investigate changes in cognitive and physical performance after 10 weeks of dual or single task training in anterior cruciate ligament (ACL) reconstructed individuals. The main questions it aims to answer are:
- Does cognitive performance in ACL reconstructed individuals change after multiple training sessions incorporating single versus dual-task?
- Does physical performance and intrinsic motivation for training change over the course of 10 weeks when performing single versus dual-task training sessions?
- What movement patterns do ACL reconstructed individuals show during a dual-task training in an immersive environment?
Researchers will compare a combined dual-task training (combined physical and cognitive training) to a single task training (physical and cognitive training separately) to see if there are changes on cognitive performance depending on the training type.
Participants will:
- Perform dual-task or single task training twice per week for 10 weeks
- Visit the clinic before and after the training period for tests
- Visit the movement laboratory once for analysis of movement patterns
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Dual-task training | Experimental | Other: Dual-task training |
| Single task training | Active comparator | Other: Single task training |
Who may qualify
- Ages
- 18 to 40 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (9 listed)
- 18-40 years old
- At least 6 months after ACL injury
- Surgically reconstructed ACL
- At least 2 hours of sports participation before the injury
- Written consent of the attending surgeon to perform intensified training methods including one-legged jumps at 6 months after surgery after the first visit
Key exclusion criteria (8 listed)
- Surgery on the contralateral leg during the last 12 months
- Acute or chronic musculoskeletal, neurological, or cardiopulmonary disorders
- Unadjusted vision problems
- Concussion during the last 6 months
- Pregnancy
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Dual-task trainingCombined simultaneous physical and cognitive training in an immersive environment | Other | Dual-task training |
| Single task trainingSequential cognitive and then physical training | Other | Single task training |
Primary outcome
Interference
Time frame: Baseline, after 5 weeks of training, after 10 weeks of training
Measured by the difference in reaction time of congruent and incongruent stimuli of the Flanker task.
Response inhibition
Time frame: Baseline, after 5 weeks of training, after 10 weeks of training
Measured by the accuracy of Go/No-Go-stimuli
6 secondary outcomes
Jumping performance - contact time
Time frame: Baseline and after 10 weeks of training
Jumping performance - peak force
Time frame: Baseline and after 10 weeks of training
Strength
Time frame: Baseline and after 10 weeks of training
Intrinsic motivation
Time frame: At the end of each training session (2x/week for 10 weeks)
Kinematics and kinetics of the lower extremities
Time frame: During dual-task training in an immersive environment
Kinematics and kinetics of the lower extremities
Time frame: Baseline and after 10 weeks of training
Results and safety
The study was stopped early (reason given: Insufficient recruitment rate to reach the targeted number in June 2026). Results are not available in the source record.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 8 Dec 2025.
- Individual participant dataSharing planned: Yes. Individual participant data will be shared if ethically and legally possible.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Dual-task training and Single task training in people with Anterior Cruciate Ligament Reconstruction Rehabilitation, run by Michelle C. Haas at 2 sites in Switzerland.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 9 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: stopped early, as of the sponsor's last update on 8 Dec 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Switzerland. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study was stopped early (reason given: Insufficient recruitment rate to reach the targeted number in June 2026). Results are not available in the source record.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Interference (time frame: Baseline, after 5 weeks of training, after 10 weeks of training). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 8 Dec 2025.