Healthy VolunteerIMVTNCT06845176
Combining Motor Imagery and Tendon Vibration on the Effectiveness of Motor Imagery
A study testing Tendon vibration (TV) and Kinesthetic motor imagery (kMI) in people with Healthy Volunteer, run by Centre Hospitalier Universitaire de Saint Etienne at 1 site in France.
Trial summary
Kinesthetic motor imagery (kMI) involves imagining the sensations of movement, activating brain regions similar to actual movement execution. It is widely used to maintain or restore motor functions, particularly in rehabilitation. Read more about this study
- Who is it for?
- Ages 18 to 50 yearsHealthy volunteers can take part
- Conditions the study is for
- Healthy Volunteer
- What is being tested?
- Tendon vibration (TV) and Kinesthetic motor imagery (kMI)
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 33 participants
- Where
- 1 siteFrance
- Study dates
- 27 Mar 2026to 1 Mar 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Men or women aged 18 to 50 years.
- Affiliated with or beneficiaries of a social security system.
- Provided written informed consent freely after being informed of the study's purpose, procedures, and potential risks.
Who cannot join
- History of pathology or surgery affecting upper limb motor function within 6 months prior to the study.
- Chronic neurological, motor, or psychiatric disorders.
- Use of neuroactive substances likely to alter corticospinal excitability (e.g., hypnotics, antiepileptics, psychotropics, muscle relaxants) during the study period.
- Contraindications to transcranial magnetic stimulation
- Simultaneous participation in another interventional study or participation in such a study within 30 days prior to this study.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
France1 site, 1 recruiting
- Recruiting
IRMIS-Hôpital Nord
Saint-Etienne, France, 42055
Diana RIMAUD, Docor of science, 0477120467 ext. 33, diana.rimaud@chu-st-etienne.fr
Lenoard FEASSON, PhD
About this study
Official title: Comparison of Three Modalities of Combining Motor Imagery and Tendon Vibration on the Effectiveness of Motor Imagery
Kinesthetic motor imagery (kMI) involves imagining the sensations of movement, activating brain regions similar to actual movement execution. It is widely used to maintain or restore motor functions, particularly in rehabilitation. Tendon vibration (TV), which stimulates proprioceptive receptors can also enhance corticospinal excitability and promote neuroplasticity. This project investigates the coupling of kMI and TV through three modalities: simultaneous application, TV application between kMI trials, or pre-application of TV to precondition the nervous system before kMI trials. The effectiveness and quality of kMI will be assessed by corticospinal excitability measurements using transcranial magnetic stimulation and EEG measures. Conducting this study in healthy participants will inform the development of optimized clinical interventions for immobilized or mobility-reduced patients.
- Conditions
- Healthy Volunteer
- Being tested
- Tendon vibration (TV), Kinesthetic motor imagery (kMI)
- Keywords
- Kinesthetic motor imagery, Tendon vibration, Corticospinal excitability, Neuroplasticity, Electroencephalography
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Tendon vibration (TV)Device
We use the VIBRAMOOV PHYSIO device which delivers local muscle vibrations at frequencies of 80 Hz and an amplitude of 1 mm.
Kinesthetic motor imagery (kMI)Other
kMI is a mental technique in which an individual visualizes performing a movement without physically executing it. This process involves the internal representation of the sensations associated with the movement, engaging neural pathways similar to those activated during actual physical movement. kMI stimulates key motor and sensory areas in the brain, promoting neuroplasticity and enhancing motor performance.
| Study group | Role | What they receive |
|---|---|---|
| Simultaneous application of TV and kMI | Experimental | Simultaneous application of Tendon Vibration and Kinesthesic Motor Imagery Receives: Device: Tendon vibration (TV); Other: Kinesthetic motor imagery (kMI) |
| TV application between kMI trials | Experimental | Tendon Vibration application between Kinesthesic Motor Imagery Receives: Device: Tendon vibration (TV); Other: Kinesthetic motor imagery (kMI) |
| TV as a pre-conditionning for kMI | Experimental | Tendon Vibration application as a pre-conditionning for Kinesthesic Motor Imagery Receives: Device: Tendon vibration (TV); Other: Kinesthetic motor imagery (kMI) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Optimization of kMI
We will measure corticospinal excitability. This will be assessed by the area (in mV.%) under the curve representing the amplitude of motor-evoked potentials (MEPs, in mV) recorded via electromyography, as a function of transcranial magnetic stimulation intensity (in % of the stimulator's maximal output) required to evoke these potentials.
Measured: 30 minutes
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Feb 2025
- Study start27 Mar 2026
- Primary completion1 Mar 2027 (estimated)
- Study completion1 Mar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Healthy VolunteerStudies of the same condition, open and under way.
- More trials run by Centre Hospitalier Universitaire de Saint EtienneThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 33 participants (estimated)
Sponsor and investigators
- Sponsor type
- University, hospital or other
- Collaborators
- Jean Monnet University
- Responsible party
- Sponsor
- Investigators
- Léonard FEASSON, PhD, Principal investigator, Centre Hospitalier Universiatire de SAINT-ETIENNE
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06845176
- Sponsor's protocol ID
- 24CH250
- Other IDs
- 2024-A02856-41
- Acronym
- IMVT
- Status last verified
- Mar 2026
- First submitted
- 20 Feb 2025
- Last updated
- 3 Apr 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: This study is being conducted in a single department of the ST-ETIENNE University Hospital.
Study at a glance
From the registry record, last updated by the sponsor on 3 Apr 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Comparison of Three Modalities of Combining Motor Imagery and Tendon Vibration on the Effectiveness of Motor Imagery
- ClinicalTrials.gov ID
- NCT06845176
- Acronym / sponsor ID
- IMVT / 24CH250
- Conditions
- Healthy Volunteer
- Keywords
- Kinesthetic motor imagery, Tendon vibration, Corticospinal excitability, Neuroplasticity, Electroencephalography
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 33 participants (estimated)
- Lead sponsor
- Centre Hospitalier Universitaire de Saint EtienneUniversity, hospital or other
- Collaborators
- Jean Monnet University
- Study start
- 27 Mar 2026 (actual)
- Primary completion
- 1 Mar 2027 (estimated)
- Study completion
- 1 Mar 2027 (estimated)
- First posted
- 25 Feb 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Kinesthetic motor imagery (kMI) involves imagining the sensations of movement, activating brain regions similar to actual movement execution. It is widely used to maintain or restore motor functions, particularly in rehabilitation. Tendon vibration (TV), which stimulates proprioceptive receptors can also enhance corticospinal excitability and promote neuroplasticity. This project investigates the coupling of kMI and TV through three modalities: simultaneous application, TV application between kMI trials, or pre-application of TV to precondition the nervous system before kMI trials. The effectiveness and quality of kMI will be assessed by corticospinal excitability measurements using transcranial magnetic stimulation and EEG measures. Conducting this study in healthy participants will inform the development of optimized clinical interventions for immobilized or mobility-reduced patients.
Study design
- Primary purpose
- Basic science
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Simultaneous application of TV and kMI | Experimental | Device: Tendon vibration (TV), Other: Kinesthetic motor imagery (kMI)Simultaneous application of Tendon Vibration and Kinesthesic Motor Imagery |
| TV application between kMI trials | Experimental | Device: Tendon vibration (TV), Other: Kinesthetic motor imagery (kMI)Tendon Vibration application between Kinesthesic Motor Imagery |
| TV as a pre-conditionning for kMI | Experimental | Device: Tendon vibration (TV), Other: Kinesthetic motor imagery (kMI)Tendon Vibration application as a pre-conditionning for Kinesthesic Motor Imagery |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Men or women aged 18 to 50 years.
- Affiliated with or beneficiaries of a social security system.
- Provided written informed consent freely after being informed of the study's purpose, procedures, and potential risks.
Key exclusion criteria (5 listed)
- History of pathology or surgery affecting upper limb motor function within 6 months prior to the study.
- Chronic neurological, motor, or psychiatric disorders.
- Use of neuroactive substances likely to alter corticospinal excitability (e.g., hypnotics, antiepileptics, psychotropics, muscle relaxants) during the study period.
- Contraindications to transcranial magnetic stimulation
- Simultaneous participation in another interventional study or participation in such a study within 30 days prior to this study.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Tendon vibration (TV)We use the VIBRAMOOV PHYSIO device which delivers local muscle vibrations at frequencies of 80 Hz and an amplitude of 1 mm. | Device | Simultaneous application of TV and kMI, TV application between kMI trials, TV as a pre-conditionning for kMI |
| Kinesthetic motor imagery (kMI)kMI is a mental technique in which an individual visualizes performing a movement without physically executing it. This process involves the internal representation of the sensations associated with the movement, engaging neural pathways similar to those activated during actual physical movement. kMI stimulates key motor and sensory areas in the brain, promoting neuroplasticity and enhancing motor performance. | Other | Simultaneous application of TV and kMI, TV application between kMI trials, TV as a pre-conditionning for kMI |
Primary outcome
Optimization of kMI
Time frame: 30 minutes
We will measure corticospinal excitability. This will be assessed by the area (in mV.%) under the curve representing the amplitude of motor-evoked potentials (MEPs, in mV) recorded via electromyography, as a function of transcranial magnetic stimulation intensity (in % of the stimulator's maximal output) required to evoke these potentials.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 3 Apr 2026.
- Individual participant dataSharing planned: No. This study is being conducted in a single department of the ST-ETIENNE University Hospital.
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Screening Protocol
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Léonard FEASSON, PhD principal investigator
Centre Hospitalier Universiatire de SAINT-ETIENNE
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Tendon vibration (TV) and Kinesthetic motor imagery (kMI) in people with Healthy Volunteer, run by Centre Hospitalier Universitaire de Saint Etienne at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 3 Apr 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Léonard FEASSON, PhD (04 77 12 03 83 ext. 33, leonard.feasson@univ-st-etienne.fr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Optimization of kMI (time frame: 30 minutes). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 3 Apr 2026.