Obesity PreventionNCT06849206
Pennington Generation Cohort
An observational study of Obesity Prevention, run by Pennington Biomedical Research Center at 1 site in United States.
Trial summary
The Pennington Generation Cohort is an observational study comprised of Louisiana families. Families will be assessed at baseline for a variety of traits and behaviors, and then followed up over time to try to understand the role of lifestyle and the environment on the risk of developing obesity and other health… Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Obesity Prevention
- How many people
- 3,000 participants
- Where
- 1 siteUnited States
- Study dates
- 24 Feb 2025to 24 Feb 2045
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Study population: Adults of child-bearing age who are planning to become pregnant, expectant parents, as well as children, adolescents, and young adults and their nuclear family members will be recruited.
Who may be able to join
- Children, adolescents, and young adults (birth through age 24 years) and their nuclear family members* and adults age 25+ who are expectant parents or are trying to conceive
- Self-reported resident of Louisiana
- Ability to understand instructions and complete all study procedures
- Able to provide informed consent (adults aged over 18 years)
- Able to provide assent (children 9 to 17 years)
- Able to communicate (oral and written) in English
Who cannot join
- Discretion of the Medical Monitor or Principal Investigator
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Pennington Biomedical Research Center
Baton Rouge, Louisiana, 70808
Peter T Katzmarzyk, PhD, 225-763-2536, peter.katzmarzyk@pbrc.edu
Peter T Katzmarzyk, PhD
About this study
The Pennington Generation Cohort is an observational study comprised of Louisiana families. Families will be assessed at baseline for a variety of traits and behaviors, and then followed up over time to try to understand the role of lifestyle and the environment on the risk of developing obesity and other health outcomes.
Read the detailed description
Pennington Biomedical's Greaux Healthy initiative partners with communities to grow healthier generations by expanding the access and reach of Pennington Biomedical's evidence-based practices for the prevention and treatment of childhood obesity. As part of Greaux Healthy, the Pennington Generation Cohort will help evaluate the impact of the program. A sample of up to 1,500 children and adolescents and their families will be recruited from throughout Louisiana. An initial physical exam will establish a baseline for each family with respect to lifestyle behaviors, genetics, and body size/composition. This longitudinal cohort will also assess the association between participation in several childhood obesity prevention and treatment programs and subsequent obesity and related health outcomes. Members of the longitudinal cohort will be followed in the future through clinical visits, questionnaires, and through optional linkages to electronic medical records and administrative databases such as the National Death Index, Social Security Death Master File, and health registry data.
- Conditions
- Obesity Prevention
- Keywords
- physical activity, obesity, diet, nutrition, families
- Medical subject headings
- Motor Activity, Obesity
What is being measured
The primary outcome is the main question the study is designed to answer.
Obesity
The development of obesity, defined using BMI z-scores during childhood, and BMI during adulthood.
Measured: From enrollment up to 20 years of follow-up.
Secondary outcomes (3)
Weight change
Change in body weight.
Measured: From enrollment up to 20 years of follow-up.
Mortality
Data from the Pennington Generation Prospective Cohort will be prospectively linked to the National Death Index for the ascertainment of mortality.
Measured: From enrollment up to 20 years of follow-up..
Cancer incidence
Data from the Pennington Generation Prospective Cohort will be prospectively linked to the Louisiana Tumor Registry for the ascertainment of incident cancer.
Measured: From enrollment up to 20 years of follow-up..
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Feb 2025
- Study start24 Feb 2025
- Primary completion24 Feb 2045 (estimated)
- Study completion24 Feb 2045 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Obesity PreventionStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 3,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Pennington Biomedical Research Center
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Peter T. Katzmarzyk, Pennington Biomedical Research Center
- Investigators
- Peter T Katzmarzyk, PhD, Principal investigator, Pennington Biomedical Research Center
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06849206
- Sponsor's protocol ID
- 2024-036
- Status last verified
- Sep 2026
- First submitted
- 19 Feb 2025
- Last updated
- 17 Sep 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: A de-identified individual-level dataset will be made available to researchers making a reasonable request to the principal investigator.
Study at a glance
From the registry record, last updated by the sponsor on 17 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Pennington Generation Cohort
- ClinicalTrials.gov ID
- NCT06849206
- Acronym / sponsor ID
- 2024-036
- Conditions
- Obesity Prevention
- Keywords
- physical activity, obesity, diet, nutrition, families
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 3,000 participants (estimated)
- Lead sponsor
- Pennington Biomedical Research CenterUniversity, hospital or other
- Study start
- 24 Feb 2025 (actual)
- Primary completion
- 24 Feb 2045 (estimated)
- Study completion
- 24 Feb 2045 (estimated)
- First posted
- 27 Feb 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The Pennington Generation Cohort is an observational study comprised of Louisiana families. Families will be assessed at baseline for a variety of traits and behaviors, and then followed up over time to try to understand the role of lifestyle and the environment on the risk of developing obesity and other health outcomes.
Detailed description
Pennington Biomedical's Greaux Healthy initiative partners with communities to grow healthier generations by expanding the access and reach of Pennington Biomedical's evidence-based practices for the prevention and treatment of childhood obesity. As part of Greaux Healthy, the Pennington Generation Cohort will help evaluate the impact of the program. A sample of up to 1,500 children and adolescents and their families will be recruited from throughout Louisiana. An initial physical exam will establish a baseline for each family with respect to lifestyle behaviors, genetics, and body size/composition. This longitudinal cohort will also assess the association between participation in several childhood obesity prevention and treatment programs and subsequent obesity and related health outcomes. Members of the longitudinal cohort will be followed in the future through clinical visits, questionnaires, and through optional linkages to electronic medical records and administrative databases such as the National Death Index, Social Security Death Master File, and health registry data.
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
- Study population
- Adults of child-bearing age who are planning to become pregnant, expectant parents, as well as children, adolescents, and young adults and their nuclear family members will be recruited.
Key inclusion criteria (6 listed)
- Children, adolescents, and young adults (birth through age 24 years) and their nuclear family members* and adults age 25+ who are expectant parents or are trying to conceive
- Self-reported resident of Louisiana
- Ability to understand instructions and complete all study procedures
- Able to provide informed consent (adults aged over 18 years)
- Able to provide assent (children 9 to 17 years)
Key exclusion criteria (1 listed)
- Discretion of the Medical Monitor or Principal Investigator
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Obesity
Time frame: From enrollment up to 20 years of follow-up.
The development of obesity, defined using BMI z-scores during childhood, and BMI during adulthood.
3 secondary outcomes
Weight change
Time frame: From enrollment up to 20 years of follow-up.
Mortality
Time frame: From enrollment up to 20 years of follow-up..
Cancer incidence
Time frame: From enrollment up to 20 years of follow-up..
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 17 Sep 2026.
- Individual participant dataSharing planned: Yes. A de-identified individual-level dataset will be made available to researchers making a reasonable request to the principal investigator.
Related trials for Obesity Prevention
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ENLIGHT Trial: ESG With Fundal Mucosal Ablation
Obesity, Obesity (Body Mass Index >30 kg/m2)
Recruiting
PreventT2 Together: Examining the Efficacy of Couple-based Lifestyle Intervention to Prevent Type 2 Diabetes
Prediabetic State, Life Style
Enrolling by invitation
EFFECT OF A ONLINE NUTRITION EDUCATION PROGRAM IN PRESCHOOLER'S FAMILIES ON THEIR ADHERENCE TO THE MEDITERRANEAN DIET
Prevention of Childhood Obesity, Community Health Education
Active, not recruiting
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Peter T Katzmarzyk, PhD principal investigator
Pennington Biomedical Research Center
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Obesity Prevention, run by Pennington Biomedical Research Center at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 17 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Peter T Katzmarzyk, PhD (225-763-2536, peter.katzmarzyk@pbrc.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Obesity (time frame: From enrollment up to 20 years of follow-up.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 17 Sep 2026.