the Augmentation of Labial Defective Wall in Fresh Extraction SocketNCT06867848
Augmentation of Facial Wall in Defective Fresh Extraction Site for Immediate Implant Placement
A study testing laminar bone membrane for labial bone augmentation in people with the Augmentation of Labial Defective Wall in Fresh Extraction Socket, run by Nuhayra Ashour Muhammed at 1 site in Egypt.
Trial summary
The study is performed to clinically and radiographically assess the efficacy of using enriched bone graft combined with slowly resorbable membrane on bone quality in immediate implant placement in extraction socket in cases with localized facial bone defect. Read more about this study
- Who is it for?
- Ages 18 to 50 yearsHealthy volunteers can take part
- Conditions the study is for
- the Augmentation of Labial Defective Wall in Fresh Extraction Socket
- What is being tested?
- laminar bone membrane for labial bone augmentation
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 12 participants
- Where
- 1 siteEgypt
- Study dates
- 15 Sep 2022to 1 Apr 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- patient with a single hopeless tooth in maxillary anterior region.
- sufficient bone apically and palatally
- presence of natural contralateral tooth for the tooth being replaced
- systemic healthy patients
Who cannot join
- extraction socket type III
- acute infection in hopeless tooth
- a heavy smoker patient
- pregnant
- had received chemotherapy or radiotherapy in previous year
Trial locations and contacts
1 site in 1 country.
About this study
The study is performed to clinically and radiographically assess the efficacy of using enriched bone graft combined with slowly resorbable membrane on bone quality in immediate implant placement in extraction socket in cases with localized facial bone defect.
Read the detailed description
The study is include twelve participants , and the patients are in rolled in two groups, group one receive implant, sticky bone and laminar bone membrane . group two receive implant, sticky bone and pericardium membrane using vestibular incision and 6 months post operative radiographically assessment is performed to measure labial bone quantity formed .
- Being tested
- laminar bone membrane for labial bone augmentation
- Keywords
- labial bone augmentation, immediate implant placement ., laminar bone membrane effect, pericardium membrane effect
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
laminar bone membrane for labial bone augmentationProcedure or surgery
Also called pericardium membrane for labial bone augmentation
adding laminar bone membrane in one group and pericardium membrane in another group with sticky bone by using vestibular incision in both groups to augment the labial bone over dental implant
| Study group | Role | What they receive |
|---|---|---|
| laminar bone membrane | Experimental | hopeless tooth extraction then immediate implant placed , then by using vestibular incision placing laminar bone membrane under the mucogingival tunnel and fill the gap between the laminar bone membrane and the implant with sticky bone Receives: Procedure: laminar bone membrane for labial bone augmentation |
| pericardium membrane | Experimental | hopeless tooth extraction then immediate implant placed , then by using vestibular incision placing pericardium membrane under the mucogingival tunnel and fill the gap between the pericardium membrane and the implant with sticky bone Receives: Procedure: laminar bone membrane for labial bone augmentation |
What is being measured
The primary outcome is the main question the study is designed to answer.
primary stability of implant in Newton centimeter and soft tissue healing
Dental implant ratchet to show implant stability and Pink esthetic score for soft tissue healing measurement
Measured: one week postoperative
Secondary outcomes (1)
labial bone thickness formation in millimeters
Cone beam computed tomography to show labial bone thickness
Measured: 6 months postoperative
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted10 Mar 2025
- Study start15 Sep 2022
- Primary completion6 Aug 2024
- Study completion1 Apr 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for the Augmentation of Labial Defective Wall in Fresh Extraction SocketStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- the study is interventional study containing two groups, each group receiving deferent type of treatment for their result comparison.
- Masking
- None (open label)
- Enrolment
- 12 participants (actual)
Sponsor and investigators
- Lead sponsor
- Nuhayra Ashour Muhammed
- Sponsor type
- Other government
- Responsible party
- Sponsor-investigator, Nuhayra Ashour Muhammed, Faculty of Dental Medicine for Girls
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06867848
- Sponsor's protocol ID
- OR SUR-102-1-E
- Status last verified
- Mar 2025
- First submitted
- 5 Jan 2025
- Last updated
- 4 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Mahmoud HMR, Al-Ahmady HH, Habba DA, Alzayani NAM, Alblowi JA, Abdelaziz LM. Influence of adding a pericardium membrane to the bioactive shield technique in vestibular socket therapy for immediate implant placement in Type II alveolar sockets: a randomized clinical trial. Saudi Dent J. 2026 Oct 5;38(10):130. doi: 10.1007/s44445-026-00219-y.
PubMed 42831977
Study at a glance
From the registry record, last updated by the sponsor on 4 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Augmentation of Facial Wall in Defective Fresh Extraction Site for Immediate Implant Placement
- ClinicalTrials.gov ID
- NCT06867848
- Acronym / sponsor ID
- OR SUR-102-1-E
- Keywords
- labial bone augmentation, immediate implant placement ., laminar bone membrane effect, pericardium membrane effect
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 12 participants (actual)
- Lead sponsor
- Nuhayra Ashour MuhammedOther government
- Study start
- 15 Sep 2022 (actual)
- Primary completion
- 6 Aug 2024 (actual)
- Study completion
- 1 Apr 2025 (actual)
- First posted
- 10 Mar 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The study is performed to clinically and radiographically assess the efficacy of using enriched bone graft combined with slowly resorbable membrane on bone quality in immediate implant placement in extraction socket in cases with localized facial bone defect.
Detailed description
The study is include twelve participants , and the patients are in rolled in two groups, group one receive implant, sticky bone and laminar bone membrane . group two receive implant, sticky bone and pericardium membrane using vestibular incision and 6 months post operative radiographically assessment is performed to measure labial bone quantity formed .
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
- Model description
- the study is interventional study containing two groups, each group receiving deferent type of treatment for their result comparison.
| Arm | Type | Receives |
|---|---|---|
| laminar bone membrane | Experimental | Procedure: laminar bone membrane for labial bone augmentationhopeless tooth extraction then immediate implant placed , then by using vestibular incision placing laminar bone membrane under the mucogingival tunnel and fill the gap between the laminar bone membrane and the implant with sticky bone |
| pericardium membrane | Experimental | Procedure: laminar bone membrane for labial bone augmentationhopeless tooth extraction then immediate implant placed , then by using vestibular incision placing pericardium membrane under the mucogingival tunnel and fill the gap between the pericardium membrane and the implant with sticky bone |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (4 listed)
- patient with a single hopeless tooth in maxillary anterior region.
- sufficient bone apically and palatally
- presence of natural contralateral tooth for the tooth being replaced
- systemic healthy patients
Key exclusion criteria (5 listed)
- extraction socket type III
- acute infection in hopeless tooth
- a heavy smoker patient
- pregnant
- had received chemotherapy or radiotherapy in previous year
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| laminar bone membrane for labial bone augmentationAlso: pericardium membrane for labial bone augmentationadding laminar bone membrane in one group and pericardium membrane in another group with sticky bone by using vestibular incision in both groups to augment the labial bone over dental implant | Procedure or surgery | laminar bone membrane, pericardium membrane |
Primary outcome
primary stability of implant in Newton centimeter and soft tissue healing
Time frame: one week postoperative
Dental implant ratchet to show implant stability and Pink esthetic score for soft tissue healing measurement
1 secondary outcome
labial bone thickness formation in millimeters
Time frame: 6 months postoperative
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Sep 2025.
- Derived from this study: PubMed 42831977Mahmoud HMR, Al-Ahmady HH, Habba DA, Alzayani NAM, Alblowi JA, Abdelaziz LM. Influence of adding a pericardium membrane to the bioactive shield technique in vestibular socket therapy for immediate implant placement in Type II alveolar sockets: a randomized clinical trial. Saudi Dent J. 2026 Oct 5;38(10):130. doi: 10.1007/s44445-026-00219-y.
- Individual participant dataSharing planned: No
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing laminar bone membrane for labial bone augmentation in people with the Augmentation of Labial Defective Wall in Fresh Extraction Socket, run by Nuhayra Ashour Muhammed at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 4 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 4 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
primary stability of implant in Newton centimeter and soft tissue healing (time frame: one week postoperative). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06867848, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Sep 2025.