Oxygen SaturationNCT06884644
Local and Systemic Oxygen Saturation During 'Death by Squats' Exercise
An observational study of Oxygen Saturation and Fatigue, run by Bundeswehr University Munich at 1 site in Germany.
Trial summary
During the exercise intervention "Death by Squats", which compasses body weight squats until maximum exertion, 25-30 subjects shall be tested for heart rate, the oxygen saturation of the vastus medialis and the triceps, resting and at maximum exertion blood lactate, as well as the rate of perceived exertion on the… Read more about this study
- Who is it for?
- Ages 18 years and olderHealthy volunteers can take part
- Conditions the study is for
- Oxygen Saturation, Fatigue, Anaerobic Threshold
- What is being tested?
- Death by Airsquat
- How many people
- 100 participants
- Where
- 1 siteGermany
- Study dates
- 8 Feb 2025to Dec 2025
- How long will I take part?
- 24 Months
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Male and female participants of 18 years and older, that are performing a CrossFit class with the EMOM workout "Death by Airsquat".
Who may be able to join
- being moderately to severely physically active al least 2 hours/week (all types of sport are eligible)
Who cannot join
- akute infections, musculoskeletal injuries
- chronic cardiovascular or pulmonary diseases (in case of uncertainty, we recommend appraisal from medical personnel)
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Germany1 site, 1 recruiting
- Recruiting
University of the Bundeswehr Munich
Munich, Bavaria, 85577
Petra Neudorfer, +49 89 6004 4181, petra.neudorfer@unibw.de
About this study
Official title: Analysis of Local and Systemic Oxygen Saturation During Monotonous Exercise Using the Example of 'Death by Squats'
During the exercise intervention "Death by Squats", which compasses body weight squats until maximum exertion, 25-30 subjects shall be tested for heart rate, the oxygen saturation of the vastus medialis and the triceps, resting and at maximum exertion blood lactate, as well as the rate of perceived exertion on the borg scale. At the end, all should indicate their primary reason for stopping (local fatigue, systemic fatigue, time constraints, motivational deficit).
Read the detailed description
Subjects in this study will be measured while they are engaged in an exercise protocol until maximum exertion, each in groups of three persons. The overall duration of the study is planned from April 2023 (start of recruitment) until December 2024 (finalization of data acquisition and analysis).
Subjects are executing a CrossFit workout which is planned as follows: Every minute, participants have to perform a given number of Airsquats (bodyweight squat). The first minute starts off with 10 repetitions, the remaining time can be used as a break. In minute two, 12 repetitions have to be done, in minute three 14 repetition, and so on. The subjects stick to this protocol until maximum exertion, in other words, until they are no longer able to execute the given repetitions within the actual minute. During the workout, heart rate is tracked by a 'Polar' chest strap, and the oxygen saturation of the vastus medialis and the triceps are measured using the 'Moxy' muscle oxygen monitor. Further, at rest and at maximum exertion, a blood lactate sample is taken (EKF lactate scout). Subjects rate their perceived exertion on the borg scale after quitting and indicate their primary reason for stopping (local fatigue in legs, systemic fatigue, time constraints).
- Conditions
- Oxygen Saturation, Fatigue, Anaerobic Threshold, Quadriceps Muscle
- Being tested
- Death by Airsquat
- Medical subject headings
- Fatigue
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Death by AirsquatDiagnostic test
Increasing number of squats have to be completed every minute (EMOM principle).
| Study group | Role | What they receive |
|---|---|---|
| Death by Airsquat Exercise | All participants follow the exercise protocol, based on the "every minute on the minute" principle:
Starting off with 10 body weight squats in the first minute (after completion, the remaining seconds can be always be used as a break). In minute two, 12 squats have to be completed. In minute three, 14 squats, and so forth. Until maximum exertion is reached and/or until the number of squats within 60 seconds can not be increased further. Every individual stops at his/her performance limit Receives: Diagnostic Test: Death by Airsquat |
What is being measured
The primary outcome is the main question the study is designed to answer.
Local and systemic SmO2 curve
Measured: From the start of the exercise intervention until individual exhaustion (expected between 15 to 30 minutes), with SmO₂ continuously recorded during exercise and final measurement taken immediately upon exhaustion.
Secondary outcomes (1)
Type of sports practiced
Measured: Questionnaire administered within 5 minutes after test completion to assess type of sports practiced.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted19 Mar 2025
- Study start8 Feb 2025
- Primary completionDec 2025 (estimated)
- Study completionDec 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Oxygen SaturationStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Prospective
- Enrolment
- 100 participants (estimated)
- Target duration
- 24 Months
Sponsor and investigators
- Lead sponsor
- Bundeswehr University Munich
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Annette Schmidt, PhD, Bundeswehr University Munich
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06884644
- Sponsor's protocol ID
- DBS23
- Status last verified
- Mar 2025
- First submitted
- 8 Feb 2025
- Last updated
- 19 Mar 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- Yes
Study at a glance
From the registry record, last updated by the sponsor on 19 Mar 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Analysis of Local and Systemic Oxygen Saturation During Monotonous Exercise Using the Example of 'Death by Squats'
- ClinicalTrials.gov ID
- NCT06884644
- Acronym / sponsor ID
- DBS23
- Conditions
- Oxygen Saturation, Fatigue, Anaerobic Threshold, Quadriceps Muscle
- Study type
- Observational
- Recruitment status
- Recruiting
- Enrolment
- 100 participants (estimated)
- Lead sponsor
- Bundeswehr University MunichUniversity, hospital or other
- Study start
- 8 Feb 2025 (actual)
- Primary completion
- Dec 2025 (estimated)
- Study completion
- Dec 2025 (estimated)
- First posted
- 19 Mar 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
During the exercise intervention "Death by Squats", which compasses body weight squats until maximum exertion, 25-30 subjects shall be tested for heart rate, the oxygen saturation of the vastus medialis and the triceps, resting and at maximum exertion blood lactate, as well as the rate of perceived exertion on the borg scale. At the end, all should indicate their primary reason for stopping (local fatigue, systemic fatigue, time constraints, motivational deficit).
Detailed description
Subjects in this study will be measured while they are engaged in an exercise protocol until maximum exertion, each in groups of three persons. The overall duration of the study is planned from April 2023 (start of recruitment) until December 2024 (finalization of data acquisition and analysis).
Subjects are executing a CrossFit workout which is planned as follows: Every minute, participants have to perform a given number of Airsquats (bodyweight squat). The first minute starts off with 10 repetitions, the remaining time can be used as a break. In minute two, 12 repetitions have to be done, in minute three 14 repetition, and so on. The subjects stick to this protocol until maximum exertion, in other words, until they are no longer able to execute the given repetitions within the actual minute. During the workout, heart rate is tracked by a 'Polar' chest strap, and the oxygen saturation of the vastus medialis and the triceps are measured using the 'Moxy' muscle oxygen monitor. Further, at rest and at maximum exertion, a blood lactate sample is taken (EKF lactate scout). Subjects rate their perceived exertion on the borg scale after quitting and indicate their primary reason for stopping (local fatigue in legs, systemic fatigue, time constraints).
Study design
- Observational model
- Cohort
- Time perspective
- Prospective
- Target follow-up
- 24 Months
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Death by Airsquat Exercise | – | Diagnostic Test: Death by AirsquatAll participants follow the exercise protocol, based on the "every minute on the minute" principle: Starting off with 10 body weight squats in the first minute (after completion, the remaining seconds can be always be used as a break). In minute two, 12 squats have to be completed. In minute three, 14 squats, and so forth. Until maximum exertion is reached and/or until the number of squats within 60 seconds can not be increased further. Every individual stops at his/her performance limit |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Male and female participants of 18 years and older, that are performing a CrossFit class with the EMOM workout "Death by Airsquat".
Key inclusion criteria (1 listed)
- being moderately to severely physically active al least 2 hours/week (all types of sport are eligible)
Key exclusion criteria (2 listed)
- akute infections, musculoskeletal injuries
- chronic cardiovascular or pulmonary diseases (in case of uncertainty, we recommend appraisal from medical personnel)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Death by AirsquatIncreasing number of squats have to be completed every minute (EMOM principle). | Diagnostic test | Death by Airsquat Exercise |
Primary outcome
Local and systemic SmO2 curve
Time frame: From the start of the exercise intervention until individual exhaustion (expected between 15 to 30 minutes), with SmO₂ continuously recorded during exercise and final measurement taken immediately upon exhaustion.
1 secondary outcome
Type of sports practiced
Time frame: Questionnaire administered within 5 minutes after test completion to assess type of sports practiced.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 19 Mar 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Oxygen Saturation and Fatigue, run by Bundeswehr University Munich at 1 site in Germany.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 19 Mar 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Germany. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Annette Schmidt, Prof (+49 89 6004 4412, annette.schmidt@unibw.de), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Local and systemic SmO2 curve (time frame: From the start of the exercise intervention until individual exhaustion (expected between 15 to 30 minutes), with SmO₂ continuously recorded during exercise and final measurement taken immediately upon exhaustion.). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 19 Mar 2025.