VaccinationNCT06890403
Can Stories Encourage the Elderly to Vaccinate? Combining Viewer-tailored Personal Narrative Videos With Informational Videos to Improve Vaccine Uptake Among Older Adults
A study testing Informational Animation Video and Personal Narrative Video in people with Vaccination, run by Johns Hopkins Bloomberg School of Public Health at 1 site in United States.
Trial summary
This study will compare the use of informational videos only, personal story videos only, and the combination of both, to see which is most effective in increasing vaccination among older adults. Read more about this study
- Who is it for?
- Ages 50 years and olderHealthy volunteers can take part
- Conditions the study is for
- Vaccination
- What is being tested?
- Informational Animation Video and Personal Narrative Video
- Type of treatment
- Vaccines, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 6,000 participants
- Where
- 1 siteUnited States
- Study dates
- 16 Sep 2025to Jan 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 years and older
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- U.S. adults aged 50 and older
Who cannot join
- Participants who do not complete the survey
- Participants who are unable or refuse to view and listen to videos on the participant's device
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
United States1 site, 1 recruiting
- Recruiting
Ipsos
New York, New York, 10016
Sergei Rodkin, 212-265-3200, Sergei.Rodkin@ipsos.com
About this study
This study will compare the use of informational videos only, personal story videos only, and the combination of both, to see which is most effective in increasing vaccination among older adults.
- Conditions
- Vaccination
- Being tested
- Informational Animation Video, Personal Narrative Video
- Keywords
- vaccine, narrative, communication, videos
- Medical subject headings
- Narration, Communication
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Informational Animation VideoBehavioural
The informational animation video will also take several minutes and will cover human papillomavirus (HPV) disease, address specific concerns when identified, and the importance and safety of HPV vaccines.
Personal Narrative VideoBehavioural
Personal narrative videos will consist of someone describing the person's own personal experience with HPV. The investigators have a collection of videos of personal narratives from different people that the investigators have cut to approximate several minutes in length so the investigators can tailor the personal narratives to match each study participant's race/ethnicity and gender as closely as possible.
| Study group | Role | What they receive |
|---|---|---|
| Control | No intervention | no videos |
| Animation Only | Experimental | informational animation video only Receives: Behavioral: Informational Animation Video |
| Narrative Only | Experimental | personal narrative video only Receives: Behavioral: Personal Narrative Video |
| Narrative Then Animation | Experimental | personal narrative video followed immediately by the informational animation video Receives: Behavioral: Informational Animation Video; Behavioral: Personal Narrative Video |
| Animation Then Narrative | Experimental | informational animation video followed immediately by the personal narrative video Receives: Behavioral: Informational Animation Video; Behavioral: Personal Narrative Video |
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of participants who receive vaccine
Vaccination status. Binary variables (received vs not received) for each vaccine recommended for older adults
Measured: 9-month follow-up
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Mar 2025
- Study start16 Sep 2025
- Primary completion24 Sep 2026 (estimated)
- Study completionJan 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for VaccinationStudies of the same condition, open and under way.
- More trials run by Johns Hopkins Bloomberg School of Public HealthThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 6,000 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Johns Hopkins Bloomberg School of Public Health
- Sponsor type
- University, hospital or other
- Collaborators
- Merck Sharp & Dohme LLC
- Responsible party
- Sponsor
- Investigators
- Daniel Salmon, PhD, Principal investigator, Johns Hopkins University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06890403
- Sponsor's protocol ID
- IRB00032331
- Status last verified
- Feb 2026
- First submitted
- 20 Mar 2025
- Last updated
- 13 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 13 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Can Stories Encourage the Elderly to Vaccinate? Combining Viewer-tailored Personal Narrative Videos With Informational Videos to Improve Vaccine Uptake Among Older Adults
- ClinicalTrials.gov ID
- NCT06890403
- Acronym / sponsor ID
- IRB00032331
- Conditions
- Vaccination
- Keywords
- vaccine, narrative, communication, videos
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 6,000 participants (estimated)
- Lead sponsor
- Johns Hopkins Bloomberg School of Public HealthUniversity, hospital or other
- Collaborators
- Merck Sharp & Dohme LLC
- Study start
- 16 Sep 2025 (actual)
- Primary completion
- 24 Sep 2026 (estimated)
- Study completion
- Jan 2027 (estimated)
- First posted
- 24 Mar 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will compare the use of informational videos only, personal story videos only, and the combination of both, to see which is most effective in increasing vaccination among older adults.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 5
| Arm | Type | Receives |
|---|---|---|
| Control | No intervention | –no videos |
| Animation Only | Experimental | Behavioral: Informational Animation Videoinformational animation video only |
| Narrative Only | Experimental | Behavioral: Personal Narrative Videopersonal narrative video only |
| Narrative Then Animation | Experimental | Behavioral: Informational Animation Video, Behavioral: Personal Narrative Videopersonal narrative video followed immediately by the informational animation video |
| Animation Then Narrative | Experimental | Behavioral: Informational Animation Video, Behavioral: Personal Narrative Videoinformational animation video followed immediately by the personal narrative video |
Who may qualify
- Ages
- 50 years and older
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (1 listed)
- U.S. adults aged 50 and older
Key exclusion criteria (2 listed)
- Participants who do not complete the survey
- Participants who are unable or refuse to view and listen to videos on the participant's device
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Informational Animation VideoThe informational animation video will also take several minutes and will cover human papillomavirus (HPV) disease, address specific concerns when identified, and the importance and safety of HPV vaccines. | Behavioural | Animation Only, Animation Then Narrative, Narrative Then Animation |
| Personal Narrative VideoPersonal narrative videos will consist of someone describing the person's own personal experience with HPV. The investigators have a collection of videos of personal narratives from different people that the investigators have cut to approximate several minutes in length so the investigators can tailor the personal narratives to match each study participant's race/ethnicity and gender as closely as possible. | Behavioural | Animation Then Narrative, Narrative Only, Narrative Then Animation |
Primary outcome
Number of participants who receive vaccine
Time frame: 9-month follow-up
Vaccination status. Binary variables (received vs not received) for each vaccine recommended for older adults
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 13 Feb 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Daniel Salmon, PhD principal investigator
Johns Hopkins University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Informational Animation Video and Personal Narrative Video in people with Vaccination, run by Johns Hopkins Bloomberg School of Public Health at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 13 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Michelle Goryn (919-357-2484, mgoryn1@jh.edu), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of participants who receive vaccine (time frame: 9-month follow-up). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 13 Feb 2026.