Vaccination UptakeNCT06890559
Enhancing Vaccination Uptake Through Points Redemption Based Financial Incentives and Digital Platforms: an Open-label Cluster Randomized Controlled Trial Utilizing Community Mobilization and Empowerment Strategies
A study testing financial incentive intervention based on a digital platform in people with Vaccination Uptake, run by Bo Yan at 1 site in China.
Trial summary
The overall goal is to develop and optimize a health digital platform and points redemption-based financial incentive interventions for the promotion of non-National Immunization Program (non-NIP) vaccination uptake and related preventative behaviors in China, and formulate a low-cost, labor-saving and replicable… Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Vaccination Uptake
- What is being tested?
- financial incentive intervention based on a digital platform
- Type of treatment
- Vaccines, Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 5,120 participants
- Where
- 1 siteChina
- Study dates
- 1 Jul 2026to Dec 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
- Do not move from the original research and implementation site within the next year;
- Voluntarily participate in the study and sign the informed consent;
- No mental disorder or cognitive impairment, able to understand and cooperate with research requirements.
Who cannot join
- Have contraindications related to vaccination;
- The state of the body during the intervention period is not suitable for vaccination.
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
China1 site, 1 recruiting
- Recruiting
Jiangshan City Disease Prevention and Control Center
Quzhou, Zhejiang, 324000
Bo Yan, 12418466@zju.edu.cn
About this study
The overall goal is to develop and optimize a health digital platform and points redemption-based financial incentive interventions for the promotion of non-National Immunization Program (non-NIP) vaccination uptake and related preventative behaviors in China, and formulate a low-cost, labor-saving and replicable pattern. The primary objective is to develop and optimize a digital platform-based point-redemption and financial incentive system and evaluate the effectiveness of the interventions for improving non-NIP vaccines coverage and related preventive behaviors.The main questions it aims to answer are:
H1: Participants allocated to the intervention group will demonstrate a 3% increase in vaccine doses of targeted non-NIP vaccines, including HPV vaccines, influenza vaccines, pneumonia vaccines, rotavirus vaccines, varicella vaccines, and haemophilus Influenza Type B polysaccharide conjugate (Hib) vaccines, compared to those in the control group at the 12-month follow-up.
Read more
H2: Participants allocated to the intervention group will exhibit a 5% increase in the prevalence of related preventive behaviors compared to those in the control group at the 12-month follow-up.
Researchers will compare the financial incentive intervention to the routine activities to see if the intervention works to improve the vacciantion rate of non-NIP vaccines.
Participants will:
- Participants can automatically input their health behaviors through the digital platform, and the back-end will verify the information with data provided by the township hospitals or community health centers.
- A QR code will be implemented at each township hospital or community health center. Participants will scan the QR code after completing vaccination or other related preventive behaviors. The digital platform will automatically record points for each completed behavior.
- Use accumulated points to redeem gifts on the system, including household goods, electronic products, and free or discounted health services.
- Conditions
- Vaccination Uptake
- Being tested
- financial incentive intervention based on a digital platform
- Keywords
- financial incentive
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
financial incentive intervention based on a digital platformBehavioural
The intervention will span a duration of 12 months. All residents in the 8 intervention subdistricts/townships are available for participation; each participant household needs to register a household account on the digital platform. Each family member who completes targeted vaccine uptake or related health behaviors can earn points through two point-recording routes. Reward points will be accumulated on a household basis to encourage family members' engagement. Points can be redeemed for gifts on the digital platform and are only valid once.
| Study group | Role | What they receive |
|---|---|---|
| financial incentive group | Active comparator | Not described Receives: Behavioral: financial incentive intervention based on a digital platform |
| Control group | No intervention | Not described |
What is being measured
The primary outcome is the main question the study is designed to answer.
The number of targeted non-NIP vaccine doses per 1,000 person-years
The primary outcome of interest is the number of targeted non-NIP vaccine doses per 1,000 person-years. The targeted vaccines in this study include HPV vaccines, influenza vaccines and pneumonia vaccines.
Measured: one year
Secondary outcomes (1)
Number of cervical cancer screenings, medical checkups for the elderly, and check-ups for children during the intervention period
Preventive behaviors related to vaccination, such as cervical cancer screening, medical checkups for the elderly,and check-ups for children during the intervention period. We will count the total number of occurrences through the participant's medical records and the number of times these behaviours are self-reported through the digital platform.
Measured: one year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted24 Mar 2025
- Study start1 Jul 2026
- Primary completionJul 2027 (estimated)
- Study completionDec 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Vaccination UptakeStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 5,120 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Bo Yan
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor-investigator, Bo Yan, Zhejiang University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06890559
- Sponsor's protocol ID
- ZGL202502-6
- Status last verified
- Sep 2026
- First submitted
- 11 Mar 2025
- Last updated
- 4 Sep 2026
- Results posted
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 4 Sep 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Enhancing Vaccination Uptake Through Points Redemption Based Financial Incentives and Digital Platforms: an Open-label Cluster Randomized Controlled Trial Utilizing Community Mobilization and Empowerment Strategies
- ClinicalTrials.gov ID
- NCT06890559
- Acronym / sponsor ID
- ZGL202502-6
- Conditions
- Vaccination Uptake
- Keywords
- financial incentive
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 5,120 participants (estimated)
- Lead sponsor
- Bo YanUniversity, hospital or other
- Study start
- 1 Jul 2026 (actual)
- Primary completion
- Jul 2027 (estimated)
- Study completion
- Dec 2027 (estimated)
- First posted
- 24 Mar 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The overall goal is to develop and optimize a health digital platform and points redemption-based financial incentive interventions for the promotion of non-National Immunization Program (non-NIP) vaccination uptake and related preventative behaviors in China, and formulate a low-cost, labor-saving and replicable pattern. The primary objective is to develop and optimize a digital platform-based point-redemption and financial incentive system and evaluate the effectiveness of the interventions for improving non-NIP vaccines coverage and related preventive behaviors.The main questions it aims to answer are:
H1: Participants allocated to the intervention group will demonstrate a 3% increase in vaccine doses of targeted non-NIP vaccines, including HPV vaccines, influenza vaccines, pneumonia vaccines, rotavirus vaccines, varicella vaccines, and haemophilus Influenza Type B polysaccharide conjugate (Hib) vaccines, compared to those in the control group at the 12-month follow-up.
H2: Participants allocated to the intervention group will exhibit a 5% increase in the prevalence of related preventive behaviors compared to those in the control group at the 12-month follow-up.
Researchers will compare the financial incentive intervention to the routine activities to see if the intervention works to improve the vacciantion rate of non-NIP vaccines.
Participants will:
- Participants can automatically input their health behaviors through the digital platform, and the back-end will verify the information with data provided by the township hospitals or community health centers.
- A QR code will be implemented at each township hospital or community health center. Participants will scan the QR code after completing vaccination or other related preventive behaviors. The digital platform will automatically record points for each completed behavior.
- Use accumulated points to redeem gifts on the system, including household goods, electronic products, and free or discounted health services.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| financial incentive group | Active comparator | Behavioral: financial incentive intervention based on a digital platform |
| Control group | No intervention | – |
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (3 listed)
- Do not move from the original research and implementation site within the next year;
- Voluntarily participate in the study and sign the informed consent;
- No mental disorder or cognitive impairment, able to understand and cooperate with research requirements.
Key exclusion criteria (2 listed)
- Have contraindications related to vaccination;
- The state of the body during the intervention period is not suitable for vaccination.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| financial incentive intervention based on a digital platformThe intervention will span a duration of 12 months. All residents in the 8 intervention subdistricts/townships are available for participation; each participant household needs to register a household account on the digital platform. Each family member who completes targeted vaccine uptake or related health behaviors can earn points through two point-recording routes. Reward points will be accumulated on a household basis to encourage family members' engagement. Points can be redeemed for gifts on the digital platform and are only valid once. | Behavioural | financial incentive group |
Primary outcome
The number of targeted non-NIP vaccine doses per 1,000 person-years
Time frame: one year
The primary outcome of interest is the number of targeted non-NIP vaccine doses per 1,000 person-years. The targeted vaccines in this study include HPV vaccines, influenza vaccines and pneumonia vaccines.
1 secondary outcome
Number of cervical cancer screenings, medical checkups for the elderly, and check-ups for children during the intervention period
Time frame: one year
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 4 Sep 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing financial incentive intervention based on a digital platform in people with Vaccination Uptake, run by Bo Yan at 1 site in China.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 4 Sep 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in China. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Bo Yan (86-13338135112, 12418466@zju.edu.cn), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The number of targeted non-NIP vaccine doses per 1,000 person-years (time frame: one year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 Sep 2026.