Distal Radius FracturesNCT06894485
Sensory Training in Distal Radius Fractures
A study testing Conventional therapy and Sensory Training in people with Distal Radius Fractures, run by Istanbul University at 1 site in Turkey (Türkiye).
Trial summary
This randomized controlled trial examines the effectiveness of sensory training in patients undergoing rehabilitation for distal radius fractures. Forty-four participants (aged 18-65, with no prior upper extremity injuries) will be randomly assigned to a control group (conventional physiotherapy) or an experimental… Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Distal Radius Fractures
- What is being tested?
- Conventional therapy and Sensory Training
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 44 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Apr 2025to 1 Apr 2026
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Aged 18-65 years
- Diagnosed with distal radius fracture
- In the rehabilitation phase after fracture healing
- No prior upper extremity injuries
- No neurological or psychiatric disorders affecting hand function
- Able to comply with the rehabilitation program
Who cannot join
- Any other musculoskeletal injury affecting the upper limb
- Previous upper extremity surgeries
- Severe neuropathy or sensory disorders
- Uncontrolled chronic pain conditions
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Turkey (Türkiye)1 site
Istanbul University-Cerrahpasa
Istanbul
TUGBA CIVI KARAASLAN, Asst. Prof. Dr., tugba.civi@iuc.edu.tr
About this study
Official title: Effectiveness of Sensory Training in Distal Radius Fractures: A Randomized Controlled Trial
This randomized controlled trial examines the effectiveness of sensory training in patients undergoing rehabilitation for distal radius fractures. Forty-four participants (aged 18-65, with no prior upper extremity injuries) will be randomly assigned to a control group (conventional physiotherapy) or an experimental group (conventional physiotherapy plus sensory training, including desensitization and proprioception exercises). Assessments will be conducted at baseline, 4 weeks, and 8 weeks using grip strength, sensory function, fine motor skills, pain level, and functional capacity measures. The study aims to compare the impact of sensory training versus conventional physiotherapy on pain reduction, sensory recovery, grip strength, and functional hand use.
Read the detailed description
This study aims to investigate the effectiveness of sensory training in patients with distal radius fractures. Designed as a randomized controlled trial, the study will include 44 participants aged 18-65 years who have not had a prior upper extremity injury and are in the rehabilitation phase after a fracture. Participants will be randomly assigned to either the control group (receiving conventional physiotherapy) or the experimental group (receiving conventional physiotherapy plus sensory training, including desensitization and proprioception exercises).
Assessments will be conducted before treatment, at 4 weeks, and at 8 weeks. The evaluation tools will include grip strength (hand dynamometer \& pinch meter), sensory function (monofilament test), fine motor skills (Nine-Hole Peg Test - NHPT), pain level (Numerical Pain Rating Scale - NPRS), and functional capacity (DASH questionnaire).
The aim of this study is to compare the effects of sensory training versus conventional physiotherapy on pain reduction, sensory recovery, grip strength, and functional hand use.
- Conditions
- Distal Radius Fractures
- Being tested
- Conventional therapy, Sensory Training
- Keywords
- Distal Radius Fractures, Sensory, Physiotherapy, Rehabilitation
- Medical subject headings
- Wrist Fractures
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Conventional therapyOther
- Conventional range of motion (ROM) exercises
- Muscle strengthening exercises
- Fine motor skill exercises
- Functional rehabilitation exercises
Sensory TrainingOther
- Desensitization training (exposure to various textures and stimuli to improve sensory tolerance)
- Proprioceptive exercises (closed-eye position sense training, weight transfer exercises)
- Tactile stimulation
| Study group | Role | What they receive |
|---|---|---|
| Control | Experimental | * Conventional range of motion (ROM) exercises
* Muscle strengthening exercises
* Fine motor skill exercises
* Functional rehabilitation exercises The group will be followed 3 times per week for 8 weeks. Receives: Other: Conventional therapy |
| Experimental | Experimental | * Conventional range of motion (ROM) exercises
* Muscle strengthening exercises
* Fine motor skill exercises
* Functional rehabilitation exercises
• Experimental Group: (Conventional therapy + Sensory Training)
* Desensitization training (exposure to various textures and stimuli to improve sensory tolerance)
* Proprioceptive exercises (closed-eye position sense training, weight transfer exercises)
* Tactile stimulation The group will be followed 3 times per week for 8 weeks. Receives: Other: Conventional therapy; Other: Sensory Training |
What is being measured
The primary outcome is the main question the study is designed to answer.
Monofilament Test
The monofilament test is a clinical assessment method used to evaluate sensory function and detect peripheral nerve damage. It is widely used in physiotherapy and neurology to measure tactile sensitivity and identify sensory impairments.
- The patient is comfortably seated, and the test area is exposed.
- Applying the monofilament:
- The monofilament is placed perpendicularly to the skin surface.
- It is gently pressed until it reaches its bending point (held for approximately 1-2 seconds).
- Patient response: The patient is asked to indicate when they feel the touch.
- Recording results: The areas where the patient does or does not feel the stimulus are noted, creating a sensory map.
Measured: on the first day, four and eight week change
Numerical Pain Rating Scale
The Numeric Pain Rating Scale (NPRS) is a measurement method based on the patient's numerical expression of pain. It is commonly used to determine the intensity of pain and track changes during the treatment process.
Test Procedure Explaining the Scale to the Patient: A scale ranging from 0 to 10 is shown to the patient. 0 = No pain, 10 = The most intense pain imaginable. The patient is asked to choose the number that best represents their current pain.
Measured: on the first day, four and eight week change
Secondary outcomes (3)
Grip Strength
Hand Dynamometer: The hand dynamometer is a device used to measure hand grip strength and is commonly used in the evaluation of hand functions.
- The device is placed on a stable surface and calibrated to ensure accurate measurement.
- The patient should sit or stand in a comfortable position, with the elbow typically bent at a 90-degree angle.
- The patient holds the dynamometer and is asked to squeeze the handle.
Pinch Meter: Pincer Meter is a device used to measure the strength of a pinching or gripping action, typically between the thumb and index finger.
- The patient should be seated comfortably or standing, with their elbow typically at a 90-degree angle.
- The device measures the force exerted between the thumb and index finger.
- The test will repeat three times, and the highest value is recorded.
Measured: on the first day, four and eight week change
Nine-Hole Peg Test
Nine-Hole Peg Test (9-HPT) is a test used to assess hand function, fine motor skills, and hand coordination. It is commonly used in neurological conditions, hand injuries, and rehabilitation processes.
Procedure:
- Preparation: A pegboard with 9 holes is placed on a flat surface, with a peg in each hole. The patient sits comfortably, and the test is performed on one hand at a time.
- Test Execution:
- Starting Position: The patient prepares by looking at the pegs placed in the starting position.
- Placing the Pegs: The patient is instructed to pick up each peg and place it into the holes one by one.
- Test Duration: The time taken to place and remove the pegs is recorded. The test is repeated on both hands.
- Results Evaluation: At the end of the test, the total time taken is recorded and used to evaluate hand function. The test is typically repeated three times, and the average time is calculated.
Measured: on the first day, four and eight week change
Disabilities of the Arm, Shoulder, and Hand (DASH) Questionnaire
The DASH Scale (Disabilities of the Arm, Shoulder, and Hand) is a widely used and valid questionnaire for assessing upper extremity function.
The DASH scale consists of 30 questions. These questions cover the difficulties patients experience with arm, shoulder, and hand functions, the level of pain they experience, and any difficulties they encounter in daily activities. Additionally, a 5-point Likert scale is used to assess the severity of the complaints (1 = no difficulty, 5 = very difficult).
Each response is scored, and a total result is obtained. The scores are then evaluated on a scale of 0-100. Lower scores indicate less disability, while higher scores indicate greater functional impairment.
Evaluation: The results are used to assess the patient's overall functional status and their response to treatment. Higher scores indicate significant difficulties with upper extremity function.
Measured: on the first day, four and eight week change
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted25 Mar 2025
- Study start1 Apr 2025 (estimated)
- Primary completion1 Apr 2026 (estimated)
- Study completion1 Apr 2026 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Distal Radius FracturesStudies of the same condition, open and under way.
- More trials run by Istanbul UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Outcomes assessor
- Enrolment
- 44 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Istanbul University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Tugba Civi Karaaslan, Istanbul University - Cerrahpasa
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06894485
- Sponsor's protocol ID
- IstanbulUr
- Status last verified
- Mar 2025
- First submitted
- 19 Mar 2025
- Last updated
- 25 Mar 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Publications
Muurling M, Lotters FJB, Geelen JE, Schouten AC, Mugge W. A long-term effect of distal radius fracture on the sensorimotor control of the wrist joint in older adults. J Hand Ther. 2021 Oct-Dec;34(4):567-576. doi: 10.1016/j.jht.2020.07.002. Epub 2020 Jul 29.
PubMed 32893099
Study at a glance
From the registry record, last updated by the sponsor on 25 Mar 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effectiveness of Sensory Training in Distal Radius Fractures: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT06894485
- Acronym / sponsor ID
- IstanbulUr
- Conditions
- Distal Radius Fractures
- Keywords
- Distal Radius Fractures, Sensory, Physiotherapy, Rehabilitation
- Study type
- Interventional
- Recruitment status
- Not yet recruiting
- Enrolment
- 44 participants (estimated)
- Lead sponsor
- Istanbul UniversityUniversity, hospital or other
- Study start
- 1 Apr 2025 (estimated)
- Primary completion
- 1 Apr 2026 (estimated)
- Study completion
- 1 Apr 2026 (estimated)
- First posted
- 25 Mar 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This randomized controlled trial examines the effectiveness of sensory training in patients undergoing rehabilitation for distal radius fractures. Forty-four participants (aged 18-65, with no prior upper extremity injuries) will be randomly assigned to a control group (conventional physiotherapy) or an experimental group (conventional physiotherapy plus sensory training, including desensitization and proprioception exercises). Assessments will be conducted at baseline, 4 weeks, and 8 weeks using grip strength, sensory function, fine motor skills, pain level, and functional capacity measures. The study aims to compare the impact of sensory training versus conventional physiotherapy on pain reduction, sensory recovery, grip strength, and functional hand use.
Detailed description
This study aims to investigate the effectiveness of sensory training in patients with distal radius fractures. Designed as a randomized controlled trial, the study will include 44 participants aged 18-65 years who have not had a prior upper extremity injury and are in the rehabilitation phase after a fracture. Participants will be randomly assigned to either the control group (receiving conventional physiotherapy) or the experimental group (receiving conventional physiotherapy plus sensory training, including desensitization and proprioception exercises).
Assessments will be conducted before treatment, at 4 weeks, and at 8 weeks. The evaluation tools will include grip strength (hand dynamometer \& pinch meter), sensory function (monofilament test), fine motor skills (Nine-Hole Peg Test - NHPT), pain level (Numerical Pain Rating Scale - NPRS), and functional capacity (DASH questionnaire).
The aim of this study is to compare the effects of sensory training versus conventional physiotherapy on pain reduction, sensory recovery, grip strength, and functional hand use.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (outcomes assessor)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Control | Experimental | Other: Conventional therapy* Conventional range of motion (ROM) exercises * Muscle strengthening exercises * Fine motor skill exercises * Functional rehabilitation exercises The group will be followed 3 times per week for 8 weeks. |
| Experimental | Experimental | Other: Conventional therapy, Other: Sensory Training* Conventional range of motion (ROM) exercises * Muscle strengthening exercises * Fine motor skill exercises * Functional rehabilitation exercises • Experimental Group: (Conventional therapy + Sensory Training) * Desensitization training (exposure to various textures and stimuli to improve sensory tolerance) * Proprioceptive exercises (closed-eye position sense training, weight transfer exercises) * Tactile stimulation The group will be followed 3 times per week for 8 weeks. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Aged 18-65 years
- Diagnosed with distal radius fracture
- In the rehabilitation phase after fracture healing
- No prior upper extremity injuries
- No neurological or psychiatric disorders affecting hand function
Key exclusion criteria (4 listed)
- Any other musculoskeletal injury affecting the upper limb
- Previous upper extremity surgeries
- Severe neuropathy or sensory disorders
- Uncontrolled chronic pain conditions
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Conventional therapy* Conventional range of motion (ROM) exercises * Muscle strengthening exercises * Fine motor skill exercises * Functional rehabilitation exercises | Other | Control, Experimental |
| Sensory Training* Desensitization training (exposure to various textures and stimuli to improve sensory tolerance) * Proprioceptive exercises (closed-eye position sense training, weight transfer exercises) * Tactile stimulation | Other | Experimental |
Primary outcome
Monofilament Test
Time frame: on the first day, four and eight week change
The monofilament test is a clinical assessment method used to evaluate sensory function and detect peripheral nerve damage. It is widely used in physiotherapy and neurology to measure tactile sensitivity and identify sensory impairments. 1. The patient is comfortably seated, and the test area is exposed. 2. Applying the monofilament: * The monofilament is placed perpendicularly to the skin surface. * It is gently pressed until it reaches its bending point (held for approximately 1-2 seconds). 3. Patient response: The patient is asked to indicate when they feel the touch. 4. Recording results: The areas where the patient does or does not feel the stimulus are noted, creating a sensory map.
Numerical Pain Rating Scale
Time frame: on the first day, four and eight week change
The Numeric Pain Rating Scale (NPRS) is a measurement method based on the patient's numerical expression of pain. It is commonly used to determine the intensity of pain and track changes during the treatment process. Test Procedure Explaining the Scale to the Patient: A scale ranging from 0 to 10 is shown to the patient. 0 = No pain, 10 = The most intense pain imaginable. The patient is asked to choose the number that best represents their current pain.
3 secondary outcomes
Grip Strength
Time frame: on the first day, four and eight week change
Nine-Hole Peg Test
Time frame: on the first day, four and eight week change
Disabilities of the Arm, Shoulder, and Hand (DASH) Questionnaire
Time frame: on the first day, four and eight week change
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 25 Mar 2025.
- Results publication: PubMed 32893099Muurling M, Lotters FJB, Geelen JE, Schouten AC, Mugge W. A long-term effect of distal radius fracture on the sensorimotor control of the wrist joint in older adults. J Hand Ther. 2021 Oct-Dec;34(4):567-576. doi: 10.1016/j.jht.2020.07.002. Epub 2020 Jul 29.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Conventional therapy and Sensory Training in people with Distal Radius Fractures, run by Istanbul University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: opening soon, as of the sponsor's last update on 25 Mar 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact TUGBA CIVI KARAASLAN, Asst. Prof. Dr. (+905343855606, tugba.civi@iuc.edu.tr), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Monofilament Test (time frame: on the first day, four and eight week change). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06894485, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 25 Mar 2025; AzTrials last refreshed its copy on 2 Nov 2026.