Knee Osteoarthritis (Knee OA)NCT06896032
Retro-walking Versus Forward-walking Training Using Underwater Treadmill in Patients With Knee Osteoarthritis
A study testing physical therapy intervention in people with Knee Osteoarthritis (Knee OA) and Osteoarthritis, run by Nourhan Atwa Said at 2 sites in Egypt.
Trial summary
The purpose of this study Will investigate and compare the effects of retro-walking and forward-walking underwater treadmill training on pain, function and ROM in subjects with chronic knee OA Read more about this study
- Who is it for?
- Ages 40 to 60 yearsHealthy volunteers can take part
- Conditions the study is for
- Knee Osteoarthritis (Knee OA), Osteoarthritis
- What is being tested?
- physical therapy intervention
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 2 sitesEgypt
- Study dates
- 30 Mar 2025to 25 Jul 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 60 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- 60 patients with chronic knee OA.
- Age ranges from 40-60 years old of both genders.
- body mass index (BMI) 25- 35kg/m2.
- The degree of osteoarthritis was mild or moderate and have a Kellgren- Lawrence radiographic grade of of1-3.
- unilateral knee osteoarthritis involvement.
Who cannot join
- hydrophobia.
- pregnancy.
- infection.
- psychiatric disorder.
- haemorrhagic diathesis.
- cardiac pacemaker.
Show all 10Show fewer
- all Subjects with deformity of hip, knee \& ankle.
- any CNS or PNS involvement.
- recent steroidal or intraarticular injections (3 months).
- systemic inflammatory disease and bone malignancy.
Trial locations and contacts
2 sites in 1 country. Contact the study team or a site near you to ask about taking part.
Egypt2 sites, 2 recruiting
- Enrolling by invitation
cairo U
Cairo, Cairo Governorate, 02
- Recruiting
cairo U
Cairo, Cairo Governorate, 02
01023770486, eslamsawilm@gmail.com
Eslam Sawilm
About this study
Official title: Effect of Retro-walking Versus Forward-walking Training Using Underwater Treadmill on Pain and Function in Patients With Knee Osteoarthritis
The purpose of this study Will investigate and compare the effects of retro-walking and forward-walking underwater treadmill training on pain, function and ROM in subjects with chronic knee OA
Read the detailed description
In the current study, Sixty subjects from both genders, the dominant side only will be involved. They will be divided in to three equal groups: group A (experimental1), group B (experimental 2), group C (control), they will be signed a consent form to share in this study which aimed to investigate the effects of retro-walking and forward-walking underwater treadmill training on pain, function and ROM in subjects with chronic knee OA
- Conditions
- Knee Osteoarthritis (Knee OA), Osteoarthritis
- Being tested
- physical therapy intervention
- Keywords
- Knee Osteoarthritis
- Medical subject headings
- Osteoarthritis, Knee, Osteoarthritis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
physical therapy interventionOther
Also called hydro therapy, aquatic therapy
retro-walking and forward-walking underwater treadmill training
| Study group | Role | What they receive |
|---|---|---|
| group A (experimental1) | Experimental | forward walking group Receives: Other: physical therapy intervention |
| group B (experimental 2) | Experimental | retro walking group Receives: Other: physical therapy intervention |
| group c | Other | control group Receives: Other: physical therapy intervention |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain intensity
Pain intensity will be measured by visual analog scale (VAS. ). It is line with worst pain at one end and no pain at the other end
Measured: up to three monthes
knee disability
knee disablity will be measured by The Western Ontario and McMaster Universities osteoarthritis index. The WOMAC is a self-administered instrument containing 24 items measuring 3 subscales: physical function (17 items), pain (5 items), and stiffness (2 items).Scores range from 0 to 96 for the total WOMAC where 0 represents the best health status and 96 the worst possible status.
Measured: up to three months
Secondary outcomes (1)
knee range of motion
knee joint rang of motion will be measured by goniometer
Measured: up to three months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted26 Mar 2025
- Study start30 Mar 2025
- Primary completion30 Jun 2025 (estimated)
- Study completion25 Jul 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Knee Osteoarthritis (Knee OA)Studies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- Retro walking and forward walking training exercise
- Masking
- Double blind
- Who is masked
- Investigator, Outcomes assessor
- Enrolment
- 60 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Nourhan Atwa Said
- Sponsor type
- University, hospital or other
- Collaborators
- Cairo University
- Responsible party
- Sponsor-investigator, Nourhan Atwa Said, Cairo University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06896032
- Sponsor's protocol ID
- P.T.REC/012/005428
- Status last verified
- Mar 2025
- First submitted
- 22 Feb 2025
- Last updated
- 16 Apr 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 16 Apr 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Retro-walking Versus Forward-walking Training Using Underwater Treadmill on Pain and Function in Patients With Knee Osteoarthritis
- ClinicalTrials.gov ID
- NCT06896032
- Acronym / sponsor ID
- P.T.REC/012/005428
- Conditions
- Knee Osteoarthritis (Knee OA), Osteoarthritis
- Keywords
- Knee Osteoarthritis
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 60 participants (estimated)
- Lead sponsor
- Nourhan Atwa SaidUniversity, hospital or other
- Collaborators
- Cairo University
- Study start
- 30 Mar 2025 (actual)
- Primary completion
- 30 Jun 2025 (estimated)
- Study completion
- 25 Jul 2025 (estimated)
- First posted
- 26 Mar 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this study Will investigate and compare the effects of retro-walking and forward-walking underwater treadmill training on pain, function and ROM in subjects with chronic knee OA
Detailed description
In the current study, Sixty subjects from both genders, the dominant side only will be involved. They will be divided in to three equal groups: group A (experimental1), group B (experimental 2), group C (control), they will be signed a consent form to share in this study which aimed to investigate the effects of retro-walking and forward-walking underwater treadmill training on pain, function and ROM in subjects with chronic knee OA
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (investigator, outcomes assessor)
- Number of arms
- 3
- Model description
- Retro walking and forward walking training exercise
| Arm | Type | Receives |
|---|---|---|
| group A (experimental1) | Experimental | Other: physical therapy interventionforward walking group |
| group B (experimental 2) | Experimental | Other: physical therapy interventionretro walking group |
| group c | Other | Other: physical therapy interventioncontrol group |
Who may qualify
- Ages
- 40 to 60 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- 60 patients with chronic knee OA.
- Age ranges from 40-60 years old of both genders.
- body mass index (BMI) 25- 35kg/m2.
- The degree of osteoarthritis was mild or moderate and have a Kellgren- Lawrence radiographic grade of of1-3.
- unilateral knee osteoarthritis involvement.
Key exclusion criteria (10 listed)
- hydrophobia.
- pregnancy.
- infection.
- psychiatric disorder.
- haemorrhagic diathesis.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| physical therapy interventionAlso: hydro therapy, aquatic therapyretro-walking and forward-walking underwater treadmill training | Other | group A (experimental1), group B (experimental 2), group c |
Primary outcome
Pain intensity
Time frame: up to three monthes
Pain intensity will be measured by visual analog scale (VAS. ). It is line with worst pain at one end and no pain at the other end
knee disability
Time frame: up to three months
knee disablity will be measured by The Western Ontario and McMaster Universities osteoarthritis index. The WOMAC is a self-administered instrument containing 24 items measuring 3 subscales: physical function (17 items), pain (5 items), and stiffness (2 items).Scores range from 0 to 96 for the total WOMAC where 0 represents the best health status and 96 the worst possible status.
1 secondary outcome
knee range of motion
Time frame: up to three months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 16 Apr 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
2 sites in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing physical therapy intervention in people with Knee Osteoarthritis (Knee OA) and Osteoarthritis, run by Nourhan Atwa Said at 2 sites in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 10 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 16 Apr 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 2 sites in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact nourhan atwa said, bacalora (+201005074315 ext. +201023770486, nourhan.atwa@icloud.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain intensity (time frame: up to three monthes). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 16 Apr 2025.