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no Condition, Basic ScienceOHSNCT06904521

OH Baseline Research Study

An observational study of no Condition, Basic Science, run by Centre for Infectious Disease Research in Zambia at 1 site in Zambia.

Completed

Finished. The study has ended and is not enrolling. Results may be posted on the official record.

Official record
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Trial summary

The One Health baseline research study is essential to comprehensively understand human, animal, and environmental health interrelation within Zambia's diverse ecosystems. The rationale for this study is grounded in three key factors: Firstly, Zambia faces significant health challenges due to zoonotic diseases, which… Read more about this study

Who is it for?
Ages 18 to 85 yearsHealthy volunteers can take part
Conditions the study is for
no Condition, Basic Science
How many people
340 participants
Where
1 siteZambia
Study dates
15 Nov 2024to 31 Jul 2025
Phase
Observational
Are there results?
None posted in the registry

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 to 85 years
  • All sexes
  • Healthy volunteers accepted
  • Adult, Older adult

Study population: Food system actors that function along the food supply chain, i.e., Farmers, Food processors, Food buyers, Informal and formal traders and regulators

Who may be able to join

  • Food system actors

Who cannot join

  • Non food system actors

Trial locations and contacts

1 site in 1 country.

Zambia1 site
  • Centre for Infectious Disease Research in Zambia

    Lusaka, Lusaka Province, 10101

Other trials in Zambia

About this study

Official title: One Health Baseline Research Study

The One Health baseline research study is essential to comprehensively understand human, animal, and environmental health interrelation within Zambia's diverse ecosystems. The rationale for this study is grounded in three key factors: Firstly, Zambia faces significant health challenges due to zoonotic diseases, which account for a considerable proportion of public health threats. This study aims to gather insights into the knowledge and practices of various system actors regarding food safety, animal disease surveillance, animal medicines controls, and one health systems regulation to provide critical data that will inform targeted interventions and policies. This research aligns with programmed activities under Zambia's National One Health Strategy 2022-2026.

Secondly, the agricultural sector, which is a cornerstone of Zambia's rural economy, heavily relies on healthy livestock and sustainable farming practices. The study will gather insights on the practices of food producers, traders, and markets, essential for the identification of potential areas of improvement and innovation. This is particularly crucial as the agricultural sector supports the livelihoods of a large portion of the population and plays a vital role in food security.

Thirdly, the One Health approach emphasises the importance of collaboration between various sectors and disciplines. This baseline study aims to ascertain levels of awareness among health professionals, veterinarians, environmental scientists, and policymakers. The data collected will serve as a foundation for future research and intervention strategies, ultimately aiming to reduce the incidence of zoonotic diseases and improve overall health outcomes.

Read the detailed description
  1. Introduction Small and medium-scale farmers in Zambia are essential to the agricultural industry, significantly impacting food security and the economy. Typically, small-scale farmers handle less than 5 hectares, concentrating on subsistence farming and local markets. In contrast, medium-scale farmers, who manage between 5 and 20 hectares, participate in subsistence and commercial agriculture. The central regulatory bodies overseeing these farmers are the Ministry of Agriculture (MoA), the Ministry of Fisheries and Livestock (MFL), and the Ministry of Green Economy and Environment (MGEE), among others. Zambia's provinces provide diverse agricultural opportunities. Agriculture dominates Central, Eastern, and Southern provinces, mainly through smallholder farmers focused on crops, livestock, and horticulture. Luapula, Muchinga, and Northern provinces excel in producing rice, cassava, and vegetables due to favourable agro-ecological conditions. In contrast, North-Western and Western provinces excel in livestock production, playing a crucial role in the nation's meat and dairy sectors. The Copperbelt and Lusaka provinces also feature a mix of commercial and smallholder farming operations, representing Zambia's vibrant agricultural environment. Small and medium-scale farmers throughout these provinces are essential in developing the country's food systems and promoting rural development. The food supply chain in Zambia includes smallholder farmers, agricultural businesses, food processors, wholesalers, and retailers. Farmers grow crops and raise livestock, while buyers purchase these products for processing or export. Retailers, from supermarkets to vendors, provide food access for consumers in urban and rural areas. This network is vital for a sustainable food supply chain, supporting livelihoods and ensuring food security in Zambia.
  2. Justification of Study The study aimed to gather evidence to support interventions aligned with the global health initiatives and the UN Sustainable Development Goals (SDGs), particularly those related to good health and well-being, zero hunger, and sustainable agriculture. Therefore, conducting this One Health baseline research study was justified by addressing pressing public health concerns, supporting the agricultural sector, promoting interdisciplinary collaboration, and contributing to national and global health objectives. The insights gathered will be instrumental in shaping effective health interventions and policies, ultimately enhancing the well-being of communities across Zambia.
  3. Research Question What knowledge do food system actors in Zambia have about One Health principles, including food safety, animal disease surveillance, controls on animal medicine, waste management, and plant health, as well as the regulatory systems for food safety and plant and animal health? The food system actors in the context of this study included a diverse group of stakeholders integral to Zambia's food safety and public health. This included small and medium-scale farmers who are primary producers (farmers producing food of animal and non-animal origin), food producers who may engage in on-farm food processing or operate as standalone processors, traders, and market operators in both formal and informal settings that facilitate the distribution and sale of food products, as well as regional regulators who oversee the enforcement of laws and standards related to food safety, plant health, and animal health.
  4. Study Aim and Objectives Aim The research focused on collecting insights regarding knowledge and practices related to food safety, animal disease surveillance, control of animal medicines, and regulation of one health system.

Objectives

  • To assess the understanding of small and medium-scale farmers about food safety and plant and animal health, including knowledge of animal medicines.
  • To assess the food safety protocols of food manufacturers, which encompass both on-farm and standalone processors.
  • To evaluate how traders and markets, both formal and informal, ensure food safety, animal and plant health, and manage waste.
  • To assess the knowledge of local inspectors on enforcing legal requirements for waste management, food safety, and plant and animal health, including disease preparedness and animal treatments.
Keywords
One Health

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Number of food system actors who have knowledge and conduct practices related to food safety, animal disease surveillance, control of animal medicines, and regulation of one health system.

    Through the use of quantitative and qualitative interviews, we will gather insights regarding knowledge and practices related to food safety, animal disease surveillance, control of animal medicines, and regulation of one health system.

    Measured: Up to 6 months

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted1 Apr 2025
  2. Study start15 Nov 2024
  3. Primary completion4 Mar 2025
  4. Study completion31 Jul 2025

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Observational
Observational model
Other
Time perspective
Cross-sectional
Enrolment
340 participants (actual)
IDs, dates and publications
ClinicalTrials.gov ID
NCT06904521
Sponsor's protocol ID
OHS Baseline 5849-2024
Other IDs
No Identifier was Issued
Acronym
OHS
Status last verified
Aug 2026
First submitted
11 Mar 2025
Last updated
6 Aug 2026
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Yes: Deidentified raw participant data will be shared with our funders.

Questions about this trial

What is this clinical trial studying?

An observational study of no Condition, Basic Science, run by Centre for Infectious Disease Research in Zambia at 1 site in Zambia.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: finished, as of the sponsor's last update on 6 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Zambia. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Number of food system actors who have knowledge and conduct practices related to food safety, animal disease surveillance, control of animal medicines, and regulation of one health system. (time frame: Up to 6 months). It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Aug 2026.

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