no Condition, Basic ScienceOHSNCT06904521
OH Baseline Research Study
An observational study of no Condition, Basic Science, run by Centre for Infectious Disease Research in Zambia at 1 site in Zambia.
Trial summary
The One Health baseline research study is essential to comprehensively understand human, animal, and environmental health interrelation within Zambia's diverse ecosystems. The rationale for this study is grounded in three key factors: Firstly, Zambia faces significant health challenges due to zoonotic diseases, which… Read more about this study
- Who is it for?
- Ages 18 to 85 yearsHealthy volunteers can take part
- Conditions the study is for
- no Condition, Basic Science
- How many people
- 340 participants
- Where
- 1 siteZambia
- Study dates
- 15 Nov 2024to 31 Jul 2025
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 85 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Study population: Food system actors that function along the food supply chain, i.e., Farmers, Food processors, Food buyers, Informal and formal traders and regulators
Who may be able to join
- Food system actors
Who cannot join
- Non food system actors
Trial locations and contacts
1 site in 1 country.
Zambia1 site
Centre for Infectious Disease Research in Zambia
Lusaka, Lusaka Province, 10101
About this study
Official title: One Health Baseline Research Study
The One Health baseline research study is essential to comprehensively understand human, animal, and environmental health interrelation within Zambia's diverse ecosystems. The rationale for this study is grounded in three key factors: Firstly, Zambia faces significant health challenges due to zoonotic diseases, which account for a considerable proportion of public health threats. This study aims to gather insights into the knowledge and practices of various system actors regarding food safety, animal disease surveillance, animal medicines controls, and one health systems regulation to provide critical data that will inform targeted interventions and policies. This research aligns with programmed activities under Zambia's National One Health Strategy 2022-2026.
Secondly, the agricultural sector, which is a cornerstone of Zambia's rural economy, heavily relies on healthy livestock and sustainable farming practices. The study will gather insights on the practices of food producers, traders, and markets, essential for the identification of potential areas of improvement and innovation. This is particularly crucial as the agricultural sector supports the livelihoods of a large portion of the population and plays a vital role in food security.
Thirdly, the One Health approach emphasises the importance of collaboration between various sectors and disciplines. This baseline study aims to ascertain levels of awareness among health professionals, veterinarians, environmental scientists, and policymakers. The data collected will serve as a foundation for future research and intervention strategies, ultimately aiming to reduce the incidence of zoonotic diseases and improve overall health outcomes.
Read the detailed description
- Introduction Small and medium-scale farmers in Zambia are essential to the agricultural industry, significantly impacting food security and the economy. Typically, small-scale farmers handle less than 5 hectares, concentrating on subsistence farming and local markets. In contrast, medium-scale farmers, who manage between 5 and 20 hectares, participate in subsistence and commercial agriculture. The central regulatory bodies overseeing these farmers are the Ministry of Agriculture (MoA), the Ministry of Fisheries and Livestock (MFL), and the Ministry of Green Economy and Environment (MGEE), among others. Zambia's provinces provide diverse agricultural opportunities. Agriculture dominates Central, Eastern, and Southern provinces, mainly through smallholder farmers focused on crops, livestock, and horticulture. Luapula, Muchinga, and Northern provinces excel in producing rice, cassava, and vegetables due to favourable agro-ecological conditions. In contrast, North-Western and Western provinces excel in livestock production, playing a crucial role in the nation's meat and dairy sectors. The Copperbelt and Lusaka provinces also feature a mix of commercial and smallholder farming operations, representing Zambia's vibrant agricultural environment. Small and medium-scale farmers throughout these provinces are essential in developing the country's food systems and promoting rural development. The food supply chain in Zambia includes smallholder farmers, agricultural businesses, food processors, wholesalers, and retailers. Farmers grow crops and raise livestock, while buyers purchase these products for processing or export. Retailers, from supermarkets to vendors, provide food access for consumers in urban and rural areas. This network is vital for a sustainable food supply chain, supporting livelihoods and ensuring food security in Zambia.
- Justification of Study The study aimed to gather evidence to support interventions aligned with the global health initiatives and the UN Sustainable Development Goals (SDGs), particularly those related to good health and well-being, zero hunger, and sustainable agriculture. Therefore, conducting this One Health baseline research study was justified by addressing pressing public health concerns, supporting the agricultural sector, promoting interdisciplinary collaboration, and contributing to national and global health objectives. The insights gathered will be instrumental in shaping effective health interventions and policies, ultimately enhancing the well-being of communities across Zambia.
- Research Question What knowledge do food system actors in Zambia have about One Health principles, including food safety, animal disease surveillance, controls on animal medicine, waste management, and plant health, as well as the regulatory systems for food safety and plant and animal health? The food system actors in the context of this study included a diverse group of stakeholders integral to Zambia's food safety and public health. This included small and medium-scale farmers who are primary producers (farmers producing food of animal and non-animal origin), food producers who may engage in on-farm food processing or operate as standalone processors, traders, and market operators in both formal and informal settings that facilitate the distribution and sale of food products, as well as regional regulators who oversee the enforcement of laws and standards related to food safety, plant health, and animal health.
- Study Aim and Objectives Aim The research focused on collecting insights regarding knowledge and practices related to food safety, animal disease surveillance, control of animal medicines, and regulation of one health system.
Objectives
- To assess the understanding of small and medium-scale farmers about food safety and plant and animal health, including knowledge of animal medicines.
- To assess the food safety protocols of food manufacturers, which encompass both on-farm and standalone processors.
- To evaluate how traders and markets, both formal and informal, ensure food safety, animal and plant health, and manage waste.
- To assess the knowledge of local inspectors on enforcing legal requirements for waste management, food safety, and plant and animal health, including disease preparedness and animal treatments.
- Conditions
- no Condition, Basic Science
- Keywords
- One Health
What is being measured
The primary outcome is the main question the study is designed to answer.
Number of food system actors who have knowledge and conduct practices related to food safety, animal disease surveillance, control of animal medicines, and regulation of one health system.
Through the use of quantitative and qualitative interviews, we will gather insights regarding knowledge and practices related to food safety, animal disease surveillance, control of animal medicines, and regulation of one health system.
Measured: Up to 6 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted1 Apr 2025
- Study start15 Nov 2024
- Primary completion4 Mar 2025
- Study completion31 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for no Condition, Basic ScienceStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Cross-sectional
- Enrolment
- 340 participants (actual)
Sponsor and investigators
- Lead sponsor
- Centre for Infectious Disease Research in Zambia
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Michelle Riblet, PhD, Principal investigator, Sustainable Food Systems IrelandPaula BarryWalsh, Veterinary Doctor, Principal investigator, Sustainable Food Systems Ireland
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06904521
- Sponsor's protocol ID
- OHS Baseline 5849-2024
- Other IDs
- No Identifier was Issued
- Acronym
- OHS
- Status last verified
- Aug 2026
- First submitted
- 11 Mar 2025
- Last updated
- 6 Aug 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Yes: Deidentified raw participant data will be shared with our funders.
Study at a glance
From the registry record, last updated by the sponsor on 6 Aug 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- One Health Baseline Research Study
- ClinicalTrials.gov ID
- NCT06904521
- Acronym / sponsor ID
- OHS / OHS Baseline 5849-2024
- Conditions
- no Condition, Basic Science
- Keywords
- One Health
- Study type
- Observational
- Recruitment status
- Completed
- Enrolment
- 340 participants (actual)
- Lead sponsor
- Centre for Infectious Disease Research in ZambiaUniversity, hospital or other
- Study start
- 15 Nov 2024 (actual)
- Primary completion
- 4 Mar 2025 (actual)
- Study completion
- 31 Jul 2025 (actual)
- First posted
- 1 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The One Health baseline research study is essential to comprehensively understand human, animal, and environmental health interrelation within Zambia's diverse ecosystems. The rationale for this study is grounded in three key factors: Firstly, Zambia faces significant health challenges due to zoonotic diseases, which account for a considerable proportion of public health threats. This study aims to gather insights into the knowledge and practices of various system actors regarding food safety, animal disease surveillance, animal medicines controls, and one health systems regulation to provide critical data that will inform targeted interventions and policies. This research aligns with programmed activities under Zambia's National One Health Strategy 2022-2026.
Secondly, the agricultural sector, which is a cornerstone of Zambia's rural economy, heavily relies on healthy livestock and sustainable farming practices. The study will gather insights on the practices of food producers, traders, and markets, essential for the identification of potential areas of improvement and innovation. This is particularly crucial as the agricultural sector supports the livelihoods of a large portion of the population and plays a vital role in food security.
Thirdly, the One Health approach emphasises the importance of collaboration between various sectors and disciplines. This baseline study aims to ascertain levels of awareness among health professionals, veterinarians, environmental scientists, and policymakers. The data collected will serve as a foundation for future research and intervention strategies, ultimately aiming to reduce the incidence of zoonotic diseases and improve overall health outcomes.
Detailed description
- Introduction Small and medium-scale farmers in Zambia are essential to the agricultural industry, significantly impacting food security and the economy. Typically, small-scale farmers handle less than 5 hectares, concentrating on subsistence farming and local markets. In contrast, medium-scale farmers, who manage between 5 and 20 hectares, participate in subsistence and commercial agriculture. The central regulatory bodies overseeing these farmers are the Ministry of Agriculture (MoA), the Ministry of Fisheries and Livestock (MFL), and the Ministry of Green Economy and Environment (MGEE), among others. Zambia's provinces provide diverse agricultural opportunities. Agriculture dominates Central, Eastern, and Southern provinces, mainly through smallholder farmers focused on crops, livestock, and horticulture. Luapula, Muchinga, and Northern provinces excel in producing rice, cassava, and vegetables due to favourable agro-ecological conditions. In contrast, North-Western and Western provinces excel in livestock production, playing a crucial role in the nation's meat and dairy sectors. The Copperbelt and Lusaka provinces also feature a mix of commercial and smallholder farming operations, representing Zambia's vibrant agricultural environment. Small and medium-scale farmers throughout these provinces are essential in developing the country's food systems and promoting rural development. The food supply chain in Zambia includes smallholder farmers, agricultural businesses, food processors, wholesalers, and retailers. Farmers grow crops and raise livestock, while buyers purchase these products for processing or export. Retailers, from supermarkets to vendors, provide food access for consumers in urban and rural areas. This network is vital for a sustainable food supply chain, supporting livelihoods and ensuring food security in Zambia.
- Justification of Study The study aimed to gather evidence to support interventions aligned with the global health initiatives and the UN Sustainable Development Goals (SDGs), particularly those related to good health and well-being, zero hunger, and sustainable agriculture. Therefore, conducting this One Health baseline research study was justified by addressing pressing public health concerns, supporting the agricultural sector, promoting interdisciplinary collaboration, and contributing to national and global health objectives. The insights gathered will be instrumental in shaping effective health interventions and policies, ultimately enhancing the well-being of communities across Zambia.
- Research Question What knowledge do food system actors in Zambia have about One Health principles, including food safety, animal disease surveillance, controls on animal medicine, waste management, and plant health, as well as the regulatory systems for food safety and plant and animal health? The food system actors in the context of this study included a diverse group of stakeholders integral to Zambia's food safety and public health. This included small and medium-scale farmers who are primary producers (farmers producing food of animal and non-animal origin), food producers who may engage in on-farm food processing or operate as standalone processors, traders, and market operators in both formal and informal settings that facilitate the distribution and sale of food products, as well as regional regulators who oversee the enforcement of laws and standards related to food safety, plant health, and animal health.
- Study Aim and Objectives Aim The research focused on collecting insights regarding knowledge and practices related to food safety, animal disease surveillance, control of animal medicines, and regulation of one health system.
Objectives
- To assess the understanding of small and medium-scale farmers about food safety and plant and animal health, including knowledge of animal medicines.
- To assess the food safety protocols of food manufacturers, which encompass both on-farm and standalone processors.
- To evaluate how traders and markets, both formal and informal, ensure food safety, animal and plant health, and manage waste.
- To assess the knowledge of local inspectors on enforcing legal requirements for waste management, food safety, and plant and animal health, including disease preparedness and animal treatments.
Study design
- Observational model
- Other
- Time perspective
- Cross-sectional
Who may qualify
- Ages
- 18 to 85 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
- Study population
- Food system actors that function along the food supply chain, i.e., Farmers, Food processors, Food buyers, Informal and formal traders and regulators
Key inclusion criteria (1 listed)
- Food system actors
Key exclusion criteria (1 listed)
- Non food system actors
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Number of food system actors who have knowledge and conduct practices related to food safety, animal disease surveillance, control of animal medicines, and regulation of one health system.
Time frame: Up to 6 months
Through the use of quantitative and qualitative interviews, we will gather insights regarding knowledge and practices related to food safety, animal disease surveillance, control of animal medicines, and regulation of one health system.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 6 Aug 2026.
- Individual participant dataSharing planned: Yes. Deidentified raw participant data will be shared with our funders.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Michelle Riblet, PhD principal investigator
Sustainable Food Systems Ireland
Paula BarryWalsh, Veterinary Doctor principal investigator
Sustainable Food Systems Ireland
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of no Condition, Basic Science, run by Centre for Infectious Disease Research in Zambia at 1 site in Zambia.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 6 Aug 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Zambia. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Number of food system actors who have knowledge and conduct practices related to food safety, animal disease surveillance, control of animal medicines, and regulation of one health system. (time frame: Up to 6 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 6 Aug 2026.