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Lymphoma PatientsNCT06920095

Progressive Muscle Relaxation Exercises on Sleep, Fatigue, Pain in Lymphoma Patients

A study testing Progressive muscle relaxation exercises in people with Lymphoma Patients, run by Istanbul Sabahattin Zaim University at 1 site in Turkey (Türkiye).

Enrolling by invitation

Enrolling by invitation. The study team selects and invites participants, usually from an existing group of patients.

Sites and contacts
Official record
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Trial summary

With regular practice, relaxation has been found to have many benefits such as reducing sensitivity to pain and fatigue, facilitating the transition to sleep, and improving quality of life. Read more about this study

Who is it for?
Ages 18 years and olderHealthy volunteers can take part
Conditions the study is for
Lymphoma Patients
What is being tested?
Progressive muscle relaxation exercises
Could I receive a placebo?
No, everyone receives an active treatment
How many people
60 participants
Where
1 siteTurkey (Türkiye)
Study dates
3 Mar 2025to 30 Jun 2025
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 18 years and older
  • All sexes
  • Healthy volunteers accepted
  • Adult, Older adult

Who may be able to join

  • Being over 18 years of age
  • Being able to communicate adequately
  • Not having a psychiatric problem
  • Those who are determined by a physician to have no physical obstacle to exercise
  • Individuals who can use technological devices
  • Patients who have had at least 3 cycles

Who cannot join

  • Those with communication problems
  • Those with psychiatric problems
  • Patients doing any exercise
  • Individuals with phones that do not have a voice recording feature
  • Individuals with phones that do not have a WhatsApp feature

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Turkey (Türkiye)1 site

  • Istanbul Sabahattin Zaim University, Faculty of Health Sciences,

    Küçükçekmece, Istanbul, 34034

Other trials in Turkey (Türkiye)

About this study

Official title: Effects of Progressive Muscle Relaxation Exercises on Sleep, Fatigue and Pain in Lymphoma Patients

With regular practice, relaxation has been found to have many benefits such as reducing sensitivity to pain and fatigue, facilitating the transition to sleep, and improving quality of life. Therefore, this study was planned to examine the effects of progressive muscle relaxation exercises applied to lymphoma patients on sleep, fatigue, and pain.

Read the detailed description

A total of 18 sessions of progressive relaxation were performed, 3 days a week for 6 weeks.

Being tested
Progressive muscle relaxation exercises

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Progressive muscle relaxation exercisesOther

    A total of 18 sessions of progressive relaxation were performed, 3 days a week for 6 weeks.

Study groups in NCT06920095
Study groupRoleWhat they receive
Progressive muscle relaxation exercisesExperimentalA total of 18 sessions of progressive relaxation were performed, 3 days a week for 6 weeks.
Receives: Other: Progressive muscle relaxation exercises
Control groupNo interventionRoutine maintenance will be applied

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Visual Analog Scale

    The patients were asked to mark their level of pain during relaxation or activities on a 10 cm vertical or horizontal line. In addition, there were forms which were numbered from 1-10 or from 1-100. The number 0 is found at the beginning of the line, and the number 10 is located at the end of the line. A value of 0 shows that there is no pain, and the value 10 expresses unendurable pain. GAS is a common scale in the assessment of pain level. A patient is asked to mark the perceived pain on this line, and the marked point is measured in cm.

    Measured: Baseline, pre-intervention (Before progressive muscle relaxation exercises applied)

  2. Visual Analog Scale

    The patients were asked to mark their level of pain during relaxation or activities on a 10 cm vertical or horizontal line. In addition, there were forms which were numbered from 1-10 or from 1-100. The number 0 is found at the beginning of the line, and the number 10 is located at the end of the line. A value of 0 shows that there is no pain, and the value 10 expresses unendurable pain. GAS is a common scale in the assessment of pain level. A patient is asked to mark the perceived pain on this line, and the marked point is measured in cm.

    Measured: After the intervention (After progressive muscle relaxation exercises applied in week 6)

  3. The Piper Fatigue Scale

    It is a 22-item scale that measures four subscales: behavior (6 items), affect (5 items), sensory (5 items), and cognition/mood (6 items). Each item has 11 response categories on a 0-10 metric with verbal descriptors anchoring the endpoints. Each subscale is scored individually and then aggregated together for an overall score, with higher scores reflecting more fatigue.

    Measured: Baseline, pre-intervention (Before progressive muscle relaxation exercises applied)

  4. The Piper Fatigue Scale

    It is a 22-item scale that measures four subscales: behavior (6 items), affect (5 items), sensory (5 items), and cognition/mood (6 items). Each item has 11 response categories on a 0-10 metric with verbal descriptors anchoring the endpoints. Each subscale is scored individually and then aggregated together for an overall score, with higher scores reflecting more fatigue.

    Measured: After the intervention (After progressive muscle relaxation exercises applied in week 6)

Secondary outcomes (2)

  1. Pittsburgh Sleep Quality Index (PSQI)

    The PSQI is a valid and consistent survey comprising 19 questions to assess the quality and amount of sleep and the existence of a sleep disorder and its level in the previous month. The scale was adapted into the Turkish language by Agargün et al. (1996). The scale consists of seven components that assess patients' subjective sleep quality, sleep delay, use of sleeping medication and dysfunction in daily activities. Each item scores in the range 0-3 points and the total score of the seven components gives the total PSQI score. The total score has a value between 0-21 and a high total score demonstrates a poor quality of sleep. A total PSQI score of ≤5 indicates "good sleep", and a score of>5 indicates "poor sleep"

    Measured: Baseline, pre-intervention (Before progressive muscle relaxation exercises applied)

  2. Pittsburgh Sleep Quality Index (PSQI)

    The PSQI is a valid and consistent survey comprising 19 questions to assess the quality and amount of sleep and the existence of a sleep disorder and its level in the previous month. The scale was adapted into the Turkish language by Agargün et al. (1996). The scale consists of seven components that assess patients' subjective sleep quality, sleep delay, use of sleeping medication and dysfunction in daily activities. Each item scores in the range 0-3 points and the total score of the seven components gives the total PSQI score. The total score has a value between 0-21 and a high total score demonstrates a poor quality of sleep. A total PSQI score of ≤5 indicates "good sleep", and a score of>5 indicates "poor sleep"

    Measured: After the intervention (After progressive muscle relaxation exercises applied in week 6)

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted9 Apr 2025
  2. Study start3 Mar 2025
  3. Primary completion7 Apr 2025 (estimated)
  4. Study completion30 Jun 2025 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Supportive care
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Participant
Enrolment
60 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT06920095
Sponsor's protocol ID
2025/01-02
Status last verified
Mar 2025
First submitted
2 Apr 2025
Last updated
9 Apr 2025
Results posted
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
No: Nonre

Publications

  • Loh EW, Shih HF, Lin CK, Huang TW. Effect of progressive muscle relaxation on postoperative pain, fatigue, and vital signs in patients with head and neck cancers: A randomized controlled trial. Patient Educ Couns. 2022 Jul;105(7):2151-2157. doi: 10.1016/j.pec.2021.10.034. Epub 2021 Nov 3.

    PubMed 34785078

  • Tan L, Fang P, Cui J, Yu H, Yu L. Effects of progressive muscle relaxation on health-related outcomes in cancer patients: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Clin Pract. 2022 Nov;49:101676. doi: 10.1016/j.ctcp.2022.101676. Epub 2022 Oct 31.

    PubMed 36332326

Questions about this trial

What is this clinical trial studying?

A study testing Progressive muscle relaxation exercises in people with Lymphoma Patients, run by Istanbul Sabahattin Zaim University at 1 site in Turkey (Türkiye).

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 6 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: enrolling by invitation, as of the sponsor's last update on 9 Apr 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Visual Analog Scale (time frame: Baseline, pre-intervention (Before progressive muscle relaxation exercises applied)). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?

On the ClinicalTrials.gov record for NCT06920095, which also lists 2 linked publications.

Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Apr 2025.

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