Fractures, HipNCT06925789
Influence of Peri-operative Anesthetic and Analgesic Care on the Outcome of Patients Undergoing Hip Fracture Surgeries. A Prospective Study
An observational study of Fractures, Hip and Local Anesthesia, run by Milton S. Hershey Medical Center.
Trial summary
The purpose of this voluntary research study is to clarify whether or not a single injection nerve block done before surgery and after surgery nerve block catheter can effectively enhance recovery in elderly hip fracture patients in terms of reduced delirium, reduced length of stay and improved surgical and anesthesia… Read more about this study
- Who is it for?
- Ages 65 years and older
- Conditions the study is for
- Fractures, Hip, Local Anesthesia, Geriatric
- What is being tested?
- Ropivacaine
- How many people
- 0 participants
- Where
- No sites listed yet
- Study dates
- 1 Jun 2025to 1 May 2028
- Phase
- Observational
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 65 years and older
- All sexes
- No healthy volunteers
- Older adult
Study population: Geriatric patients 65 years old and older, Who have a fractured neck of the femur.
Who may be able to join
- Undergoing anesthesia for hip fracture surgery.
- Patients with fracture neck of femur fractures.
- Geriatric patients. (65 years and older)
Who cannot join
- Non-fracture hip patients
- non-geriatric patients. (Below 65 years old)
- Patients not able to consent themselves
- Non- English-speaking patients
About this study
The purpose of this voluntary research study is to clarify whether or not a single injection nerve block done before surgery and after surgery nerve block catheter can effectively enhance recovery in elderly hip fracture patients in terms of reduced delirium, reduced length of stay and improved surgical and anesthesia outcomes. Delirium is a serious change in mental abilities. It results in confused thinking and a lack of awareness of someone's surroundings. The disorder usually comes on fast - within hours or a few days. Prolonged hospital stay is one of the risk factors for onset of delirium.
- Conditions
- Fractures, Hip, Local Anesthesia, Geriatric, Nerve Block
- Being tested
- Ropivacaine
- Keywords
- Hip Fracture, Nerve blocks, Geriatric, Local anesthesia, Post operative outcomes
- Medical subject headings
- Hip Fractures
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
RopivacaineDrug
The nerve block is performed when the patients are admitted to the hospital with diagnosed hip fractures. And another nerve block with catheter is performed for post-operative pain control in geriatric population with 0.25% Ropivacaine 30mls.
| Study group | Role | What they receive |
|---|---|---|
| Local anesthesia to treat hip fracture in geriatric patients | Not described Receives: Drug: Ropivacaine |
What is being measured
The primary outcome is the main question the study is designed to answer.
Pain Control
Pain control is determined by the Likert pain scale, where 0 is no pain and 10 as severe pain
Measured: up to 48 hours post hospital admission.
Opioid Use
Identification of opioid use via the EMR, Opioids usage is measured at as number of morphine equivalents during the hospital admission.
Measured: up to 48 hours post hospital admission.
Secondary outcomes (1)
Delirium score
Delirium score is calculated using the FLACC score, where FLACC score of 0 is relaxed and comfortable and FLACC score of 7-10 is severe delirium.
Measured: up to 48 hours post hospital admission.
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted13 Apr 2025
- Study start1 Jun 2025 (estimated)
- Primary completion1 Dec 2027 (estimated)
- Study completion1 May 2028 (estimated)
Why it stopped: We changed the study design.
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Fractures, HipStudies of the same condition, open and under way.
- More trials run by Milton S. Hershey Medical CenterThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Prospective
- Enrolment
- 0 participants (actual)
Sponsor and investigators
- Lead sponsor
- Milton S. Hershey Medical Center
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Shubha Srinivasareddy, Milton S. Hershey Medical Center
- Investigators
- Shubha Srinivasareddy, MD, Principal investigator, Penn State Health
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06925789
- Sponsor's protocol ID
- Study 25751
- Status last verified
- Sep 2026
- First submitted
- 7 Apr 2025
- Last updated
- 2 Oct 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- Yes
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 2 Oct 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Influence of Peri-operative Anesthetic and Analgesic Care on the Outcome of Patients Undergoing Hip Fracture Surgeries. A Prospective Study
- ClinicalTrials.gov ID
- NCT06925789
- Acronym / sponsor ID
- Study 25751
- Conditions
- Fractures, Hip, Local Anesthesia, Geriatric, Nerve Block
- Keywords
- Hip Fracture, Nerve blocks, Geriatric, Local anesthesia, Post operative outcomes
- Study type
- Observational
- Recruitment status
- WithdrawnReason stopped: We changed the study design.
- Enrolment
- 0 participants (actual)
- Lead sponsor
- Milton S. Hershey Medical CenterUniversity, hospital or other
- Study start
- 1 Jun 2025 (estimated)
- Primary completion
- 1 Dec 2027 (estimated)
- Study completion
- 1 May 2028 (estimated)
- First posted
- 13 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
The purpose of this voluntary research study is to clarify whether or not a single injection nerve block done before surgery and after surgery nerve block catheter can effectively enhance recovery in elderly hip fracture patients in terms of reduced delirium, reduced length of stay and improved surgical and anesthesia outcomes. Delirium is a serious change in mental abilities. It results in confused thinking and a lack of awareness of someone's surroundings. The disorder usually comes on fast - within hours or a few days. Prolonged hospital stay is one of the risk factors for onset of delirium.
Study design
- Observational model
- Other
- Time perspective
- Prospective
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| Local anesthesia to treat hip fracture in geriatric patients | – | Drug: Ropivacaine |
Who may qualify
- Ages
- 65 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Older adult
- Study population
- Geriatric patients 65 years old and older, Who have a fractured neck of the femur.
Key inclusion criteria (3 listed)
- Undergoing anesthesia for hip fracture surgery.
- Patients with fracture neck of femur fractures.
- Geriatric patients. (65 years and older)
Key exclusion criteria (4 listed)
- Non-fracture hip patients
- non-geriatric patients. (Below 65 years old)
- Patients not able to consent themselves
- Non- English-speaking patients
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| RopivacaineThe nerve block is performed when the patients are admitted to the hospital with diagnosed hip fractures. And another nerve block with catheter is performed for post-operative pain control in geriatric population with 0.25% Ropivacaine 30mls. | Drug | Local anesthesia to treat hip fracture in geriatric patients |
Primary outcome
Pain Control
Time frame: up to 48 hours post hospital admission.
Pain control is determined by the Likert pain scale, where 0 is no pain and 10 as severe pain
Opioid Use
Time frame: up to 48 hours post hospital admission.
Identification of opioid use via the EMR, Opioids usage is measured at as number of morphine equivalents during the hospital admission.
1 secondary outcome
Delirium score
Time frame: up to 48 hours post hospital admission.
Results and safety
The study was withdrawn before enrolling participants, so there are no results.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 2 Oct 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Shubha Srinivasareddy, MD principal investigator
Penn State Health
Questions about this trial
What is this clinical trial studying?
An observational study of Fractures, Hip and Local Anesthesia, run by Milton S. Hershey Medical Center.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 4 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: withdrawn, as of the sponsor's last update on 2 Oct 2026. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study was withdrawn before enrolling participants, so there are no results.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Pain Control (time frame: up to 48 hours post hospital admission.). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 2 Oct 2026.