Third MolarNCT06933979
Positional Changes of Mandibular Molar After Orthodontic Treatment
An observational study of Third Molar, run by Fayoum University at 1 site in Egypt.
Trial summary
This retrospective study was carried out on pre and posttreatment digital standardized panoramic radiographs of 30 cases previously orthodontically treated with four first premolar extraction. Read more about this study
- Who is it for?
- Ages 14 to 18 years
- Conditions the study is for
- Third Molar
- How many people
- 30 participants
- Where
- 1 siteEgypt
- Study dates
- 23 Feb 2025to 25 Apr 2025
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 14 to 18 years
- All sexes
- Child, Adult
Study population: Sample size calculation estimated the minimum total required sample size (n) was found to be (27). The sample size was increased to (30) account for sample variability and to improve the robustness of statistical testing
Who may be able to join
- class I malocclusion cases (0 < ANB < 4) with moderate crowding
Who cannot join
- Absence of all permanent teeth including mandibular third molars.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Changes in the Position of Mandibular Third Molar in Orthodontically Treated Patients With First Premolars Extraction
This retrospective study was carried out on pre and posttreatment digital standardized panoramic radiographs of 30 cases previously orthodontically treated with four first premolar extraction.
- Conditions
- Third Molar
- Keywords
- orthodontic treatment, premolar extraction
What is being measured
The primary outcome is the main question the study is designed to answer.
Assessment of mandibular third molar positional variation
measure angles:• LA-ISL: The inward angle (towards the 2nd molar) between long axis of mandibular third molar and the inter-sigmoid line (line connecting the deepest point of the right and left sigmoid notch of the mandible).
- LA-IMB: The inward angle between long axis of mandibular third molar and the inferior border of the mandible.
Measured: 2 years
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 Apr 2025
- Study start23 Feb 2025
- Primary completion20 Apr 2025 (estimated)
- Study completion25 Apr 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (1)Papers the sponsor has linked to this study.
- Other trials for Third MolarStudies of the same condition, open and under way.
- More trials run by Fayoum UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Cohort
- Time perspective
- Retrospective
- Enrolment
- 30 participants (actual)
Sponsor and investigators
- Lead sponsor
- Fayoum University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Shereen Aly El-Mahlawy, Fayoum University
- Investigators
- Shereen A Mahlawy, PHD, Principal investigator, lecturer of orthodontics, faculty of dentistry, Fayoum universityclinical cT trial, Study director, Clinical trials.gov
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06933979
- Sponsor's protocol ID
- wisdom
- Status last verified
- Apr 2025
- First submitted
- 26 Mar 2025
- Last updated
- 18 Apr 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- Undecided
Publications
Zarin DA, Tse T, Williams RJ, Califf RM, Ide NC. The ClinicalTrials.gov results database--update and key issues. N Engl J Med. 2011 Mar 3;364(9):852-60. doi: 10.1056/NEJMsa1012065.
PubMed 21366476
Study at a glance
From the registry record, last updated by the sponsor on 18 Apr 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Changes in the Position of Mandibular Third Molar in Orthodontically Treated Patients With First Premolars Extraction
- ClinicalTrials.gov ID
- NCT06933979
- Acronym / sponsor ID
- wisdom
- Conditions
- Third Molar
- Keywords
- orthodontic treatment, premolar extraction
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 30 participants (actual)
- Lead sponsor
- Fayoum UniversityUniversity, hospital or other
- Study start
- 23 Feb 2025 (actual)
- Primary completion
- 20 Apr 2025 (estimated)
- Study completion
- 25 Apr 2025 (estimated)
- First posted
- 18 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This retrospective study was carried out on pre and posttreatment digital standardized panoramic radiographs of 30 cases previously orthodontically treated with four first premolar extraction.
Study design
- Observational model
- Cohort
- Time perspective
- Retrospective
Who may qualify
- Ages
- 14 to 18 years
- Sex
- All
- Age groups
- Child, Adult
- Study population
- Sample size calculation estimated the minimum total required sample size (n) was found to be (27). The sample size was increased to (30) account for sample variability and to improve the robustness of statistical testing
Key inclusion criteria (1 listed)
- class I malocclusion cases (0 < ANB < 4) with moderate crowding
Key exclusion criteria (1 listed)
- Absence of all permanent teeth including mandibular third molars.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Assessment of mandibular third molar positional variation
Time frame: 2 years
measure angles:• LA-ISL: The inward angle (towards the 2nd molar) between long axis of mandibular third molar and the inter-sigmoid line (line connecting the deepest point of the right and left sigmoid notch of the mandible). • LA-IMB: The inward angle between long axis of mandibular third molar and the inferior border of the mandible.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 Apr 2025.
- Results publication: PubMed 21366476Zarin DA, Tse T, Williams RJ, Califf RM, Ide NC. The ClinicalTrials.gov results database--update and key issues. N Engl J Med. 2011 Mar 3;364(9):852-60. doi: 10.1056/NEJMsa1012065.
- Individual participant dataSharing planned: Undecided
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Shereen A Mahlawy, PHD principal investigator
lecturer of orthodontics, faculty of dentistry, Fayoum university
clinical cT trial study director
Clinical trials.gov
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
An observational study of Third Molar, run by Fayoum University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 1 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 18 Apr 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Assessment of mandibular third molar positional variation (time frame: 2 years). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06933979, which also lists 1 linked publication.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 Apr 2025.