OsteoporosisNCT06946316
Dairy vs Plant-based Beverages for Improving Bone Health During Exercise
A study testing Nutritional supplementation during a 12 month resistance training program in people with Osteoporosis, run by University of Saskatchewan at 1 site in Canada.
Trial summary
This study will evaluate the effects of consuming dairy milk versus two plant-based beverages (pea-based, and almond-based) after resistance training sessions (3 times per week for 12 months) on bone properties (bone mineral density, bone geometry), body composition, strength, and functional performance in… Read more about this study
- Who is it for?
- Any ageHealthy volunteers can take part
- Conditions the study is for
- Osteoporosis
- What is being tested?
- Nutritional supplementation during a 12 month resistance training program
- Could I receive a placebo?
- Yes, some participants may receive a placebo
- How many people
- 150 participants
- Where
- 1 siteCanada
- Study dates
- 30 May 2025to 30 Aug 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages Any age
- All sexes
- Healthy volunteers accepted
- Child, Adult, Older adult
Who may be able to join
- Women need to be postmenopausal (no age limit)
- Men need to be 50y or older
Who cannot join
- Taking medications that might affect bone
- Conditions that might preclude participating in a resistance-training program (determined by the "Get Active Questionnaire").
- Planning 6 weeks of travel during the 12 month intervention period
- Planning major surgery during the 12 month intervention period
- Already strength training greater than 2 days per week for 30 minutes or longer per session
- Allergies to ingredients in the beverages
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Canada1 site, 1 recruiting
- Recruiting
College of Kinesiology University of Saskatchewan
Saskatoon, Saskatchewan, S7K 2X2
Philip Chilibeck, PhD, 3062303849, phil.chilibeck@usask.ca
About this study
Official title: Dairy Versus Plant-based Beverages Combined With Resistance-training for Improving Bone Health
This study will evaluate the effects of consuming dairy milk versus two plant-based beverages (pea-based, and almond-based) after resistance training sessions (3 times per week for 12 months) on bone properties (bone mineral density, bone geometry), body composition, strength, and functional performance in post-menopausal women and men 50y and older.
Read the detailed description
The purpose of the study is to compare consumption of dairy milk (1% chocolate milk) to plant-based beverages (protein-matched pea beverage and low-protein almond beverage) after resistance-training sessions on bone mineral density, bone geometric properties, lean tissue and fat mass, muscular strength, and functional performance. One-hundred and fifty postmenopausal women and men 50y or older will be randomized to one of three groups: 1) Dairy milk; 2) pea-beverage; 3) almond beverage. The study will be double-blind, accomplished by chocolate flavoring of each beverage. Participants will do supervised strength-training sessions three times per week for 12 months. After each strength-training session, participants will consume 375 ml of their beverage and then consume 375 ml of their beverage again one hour later.
- Conditions
- Osteoporosis
- Being tested
- Nutritional supplementation during a 12 month resistance training program
- Medical subject headings
- Osteoporosis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Nutritional supplementation during a 12 month resistance training programDietary supplement
1% chocolate milk
Nutritional supplementation during a 12 month resistance training programDietary supplement
pea-based beverage
Nutritional supplementation during a 12 month resistance training programDietary supplement
almond-based beverage
| Study group | Role | What they receive |
|---|---|---|
| 1% chocolate milk | Experimental | 375 ml of 1% chocolate milk consumed immediately after resistance training sessions + 375 ml of chocolate milk consumed 1 hour after resistance training sessions Receives: Dietary Supplement: Nutritional supplementation during a 12 month resistance training program |
| Pea-based beverage | Experimental | 375 ml of pea beverage consumed immediately after resistance training sessions + 375 ml of pea beverage consumed 1 hour after resistance training sessions Receives: Dietary Supplement: Nutritional supplementation during a 12 month resistance training program |
| Almond beverage | Placebo comparator | 375 ml of almond beverage consumed immediately after resistance training sessions + 375 ml of almond beverage consumed 1 hour after resistance training sessions Receives: Dietary Supplement: Nutritional supplementation during a 12 month resistance training program |
What is being measured
The primary outcome is the main question the study is designed to answer.
Change in section modulus at the hip (cm to the power of 3)
Section modulus measured by dual energy X-ray absorptiometry
Measured: 12 months
Secondary outcomes (12)
Change in lumbar spine bone mineral density (g/cm-squared)
Lumbar spine bone mineral density measured by dual energy X-ray absorptiometry
Measured: 12 months
Change in hip bone mineral density (g/cm-squared)
Hip bone mineral density measured by dual energy X-ray absorptiometry
Measured: 12 months
Change in cross-sectional area at the hip (cm-squared)
Cross-sectional area measured by dual energy X-ray absorptiometry
Measured: 12 months
Change in cortical thickness at the hip (cm)
Cortical thickness measured by dual energy X-ray absorptiometry
Measured: 12 months
Change in buckling ratio at the hip (no units)
Buckling ratio measured by dual energy X-ray absorptiometry
Measured: 12 months
Change in bench press strength (kg)
Bench press strength determine from 1-repetition maximum
Measured: 6 and 12 months
Change in knee extension strength (kg)
Knee extension strength determined from 1-repetition maxium
Measured: 6 and 12 months
Change in lean tissue mass (kg)
Lean tissue mass measured by dual energy X-ray absorptiometry
Measured: 12 months
Change in fat mass (kg)
Fat mass measured by dual energy X-ray absorptiometry
Measured: 12 months
change in 30 second sit to stand (number of repetitions)
Maximal number of times sitting and standing in 30 seconds
Measured: 6 and 12 months
Change in walking speed (m/s)
walking speed measured over 10 m
Measured: 6 and 12 months
Change in timed up and go performance (s)
Time for standing from a chair, walking 6 meters and sitting back down
Measured: 6 and 12 months
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Apr 2025
- Study start30 May 2025
- Primary completion30 May 2027 (estimated)
- Study completion30 Aug 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for OsteoporosisStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind
- Who is masked
- Participant, Investigator, Outcomes assessor
- Enrolment
- 150 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University of Saskatchewan
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Phil Chilibeck, University of Saskatchewan
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06946316
- Sponsor's protocol ID
- 361218
- Status last verified
- Feb 2026
- First submitted
- 19 Apr 2025
- Last updated
- 23 Feb 2026
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 23 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Dairy Versus Plant-based Beverages Combined With Resistance-training for Improving Bone Health
- ClinicalTrials.gov ID
- NCT06946316
- Acronym / sponsor ID
- 361218
- Conditions
- Osteoporosis
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 150 participants (estimated)
- Lead sponsor
- University of SaskatchewanUniversity, hospital or other
- Study start
- 30 May 2025 (actual)
- Primary completion
- 30 May 2027 (estimated)
- Study completion
- 30 Aug 2027 (estimated)
- First posted
- 27 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will evaluate the effects of consuming dairy milk versus two plant-based beverages (pea-based, and almond-based) after resistance training sessions (3 times per week for 12 months) on bone properties (bone mineral density, bone geometry), body composition, strength, and functional performance in post-menopausal women and men 50y and older.
Detailed description
The purpose of the study is to compare consumption of dairy milk (1% chocolate milk) to plant-based beverages (protein-matched pea beverage and low-protein almond beverage) after resistance-training sessions on bone mineral density, bone geometric properties, lean tissue and fat mass, muscular strength, and functional performance. One-hundred and fifty postmenopausal women and men 50y or older will be randomized to one of three groups: 1) Dairy milk; 2) pea-beverage; 3) almond beverage. The study will be double-blind, accomplished by chocolate flavoring of each beverage. Participants will do supervised strength-training sessions three times per week for 12 months. After each strength-training session, participants will consume 375 ml of their beverage and then consume 375 ml of their beverage again one hour later.
Study design
- Primary purpose
- Prevention
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Triple blind (participant, investigator, outcomes assessor)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| 1% chocolate milk | Experimental | Dietary Supplement: Nutritional supplementation during a 12 month resistance training program375 ml of 1% chocolate milk consumed immediately after resistance training sessions + 375 ml of chocolate milk consumed 1 hour after resistance training sessions |
| Pea-based beverage | Experimental | Dietary Supplement: Nutritional supplementation during a 12 month resistance training program375 ml of pea beverage consumed immediately after resistance training sessions + 375 ml of pea beverage consumed 1 hour after resistance training sessions |
| Almond beverage | Placebo comparator | Dietary Supplement: Nutritional supplementation during a 12 month resistance training program375 ml of almond beverage consumed immediately after resistance training sessions + 375 ml of almond beverage consumed 1 hour after resistance training sessions |
Who may qualify
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Child, Adult, Older adult
Key inclusion criteria (2 listed)
- Women need to be postmenopausal (no age limit)
- Men need to be 50y or older
Key exclusion criteria (6 listed)
- Taking medications that might affect bone
- Conditions that might preclude participating in a resistance-training program (determined by the "Get Active Questionnaire").
- Planning 6 weeks of travel during the 12 month intervention period
- Planning major surgery during the 12 month intervention period
- Already strength training greater than 2 days per week for 30 minutes or longer per session
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Nutritional supplementation during a 12 month resistance training program1% chocolate milk | Dietary supplement | 1% chocolate milk |
| Nutritional supplementation during a 12 month resistance training programpea-based beverage | Dietary supplement | Pea-based beverage |
| Nutritional supplementation during a 12 month resistance training programalmond-based beverage | Dietary supplement | Almond beverage |
Primary outcome
Change in section modulus at the hip (cm to the power of 3)
Time frame: 12 months
Section modulus measured by dual energy X-ray absorptiometry
12 secondary outcomes
Change in lumbar spine bone mineral density (g/cm-squared)
Time frame: 12 months
Change in hip bone mineral density (g/cm-squared)
Time frame: 12 months
Change in cross-sectional area at the hip (cm-squared)
Time frame: 12 months
Change in cortical thickness at the hip (cm)
Time frame: 12 months
Change in buckling ratio at the hip (no units)
Time frame: 12 months
Change in bench press strength (kg)
Time frame: 6 and 12 months
Change in knee extension strength (kg)
Time frame: 6 and 12 months
Change in lean tissue mass (kg)
Time frame: 12 months
Change in fat mass (kg)
Time frame: 12 months
change in 30 second sit to stand (number of repetitions)
Time frame: 6 and 12 months
Change in walking speed (m/s)
Time frame: 6 and 12 months
Change in timed up and go performance (s)
Time frame: 6 and 12 months
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 Feb 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Nutritional supplementation during a 12 month resistance training program in people with Osteoporosis, run by University of Saskatchewan at 1 site in Canada.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 6 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 23 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Canada. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. Some participants in this study may receive a placebo. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Philip Chilibeck, PhD (3062303849, phil.chilibeck@usask.ca), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Change in section modulus at the hip (cm to the power of 3) (time frame: 12 months). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 Feb 2026.