Subacute StrokeNCT06947343
Effect of Action Observation Therapy in Comparison to Motor Relearning Program on Balance and Mobility Among Subacute Stroke Patients
A study testing ACTION OBSERVATION THERAPY and MOTOR RELEARNING PROGRAM in people with Subacute Stroke and Cerebral Stroke, run by Foundation University Islamabad at 1 site in Pakistan.
Trial summary
This study is a randomized controlled trial. The purpose of this study is to determine the effect of Action Observation Therapy in Comparison to a Motor Relearning Program on Balance and Mobility among subacute stroke patients. Read more about this study
- Who is it for?
- Ages 45 years and older
- Conditions the study is for
- Subacute Stroke, Cerebral Stroke, Cerebrovascular Stroke
- What is being tested?
- ACTION OBSERVATION THERAPY and MOTOR RELEARNING PROGRAM
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 30 participants
- Where
- 1 sitePakistan
- Study dates
- 22 Jul 2024to 15 Jun 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 45 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Both genders, male and female
- Ischemic stroke patients
- Age 45 years and above
- MMSE>24
- Able to stand independently for 1 minute
- Patient can maintain starting sitting static position for 10 seconds without arm rest
Who cannot join
- Any other neurological disorder
- Orthopedic conditions(fracture) affecting balance and mobility
- Visual or auditory impairments
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
Foundation University College of Physical Therapy
Islamabad, 44000
Furqan Ahmed Siddiqi, PhD in Rehabilitation Sciences, +923004414981, principal.fucp@fui.edu.pk
About this study
This study is a randomized controlled trial. The purpose of this study is to determine the effect of Action Observation Therapy in Comparison to a Motor Relearning Program on Balance and Mobility among subacute stroke patients.
Read the detailed description
Action observation therapy has proven its positive effects in improving functional performance in stroke patients compared to other neurological and musculoskeletal conditions motor relearning program is also very effective in improving functional performance in stroke patients but previous studies have shown individual effects of AOT and MRP but there is no comparison of AOT with MRP on balance and mobility.
as a result, this study aims to contribute new data to the sparse literature on subacute stroke patients.
The research finidings could provide valuable insights into potential benefits, encouraging evidence-based practices.
- Being tested
- ACTION OBSERVATION THERAPY, MOTOR RELEARNING PROGRAM
- Keywords
- Action observation therapy, Motor relearning program
- Medical subject headings
- Stroke
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
ACTION OBSERVATION THERAPYProcedure or surgery
functional AOT with visual feedback and physical training after watching a video 30mins session, 3times/week total 8weeks 3mins for observation phase, 2min for action execution Stage 1, sitting position (static and dynamic balance) exercises for trunk flexion, upper and lower trunk rotation multidirectional reaching to pick up any object from different directions, forward, lateral, and diagonal reaching Stage 2, sit to stand and stand to sit from sitting to standing, trunk flexed, hips and knees 90 degree flexed, feet behind knee, 15cm apart, then standing, trunk extension hips knees extend feet apart and vice vers 4phases of sit to stand, seat off, standing, seat on, sitting in sitting position dorsiflexion training, flexion extension training knee joint the right hand touches the left foot and viceversa pick up an object from floor stage3, standing balance weight shifting, front, back, sideways, left and right head and trunk movements in different directions while standing
MOTOR RELEARNING PROGRAMProcedure or surgery
Motor relearning program, interventional group B, based on task-oriented training 30mins, 3times/week total 8weeks stage 1, balanced sitting exercises for trunk flexion and rotation, feet and knees 15cm apart multidirectional reaching while seated forward, lateral and diagonal reaching to pick up any thing from different directions butt walking scooting on bed stage 2, standing up and sitting down transition from a seated position on a firm flat surface with no armrests to standing with an upright posture, upper body vertical and feet placed backward followed by sitting down by flexing hips,knees and ankle prerequisited of sit to stand, 4phases in sitting dorsiflexion training, flexion extension training of knee joint right hand touch to left foot and viceversa picking up objects from floor stage3, balanced standing weight shifting head and trunk movemnts while standing with feetapart standing unsupported with eyes closed multidirectional reaching
| Study group | Role | What they receive |
|---|---|---|
| Action Observation Therapy GROUP | Experimental | functional AOT with visual feedback and physcial training after watching a video 30mins session, 3times/week total 8weeks 3mins for observation phase, 2min for action execution stage 1, sitting position (static and dynamic balance) exercies for trunk flexion, upper and lower trunk rotation multidirectional reaching to pickup any object from different directions,foward,lateral and diagnol reaching stage 2, sit to stand and stand to sit from sitting to standing, trunk flexed, hips and knees 90 degree flexed, feet behind knee, 15cm apart, then standing, trunk extension hips knees extend feet apart and viceversa 4phases of sit to stand, seat off, standing, seat on, sitting in sitting position dorsiflexion training, flexion extension training knee joint the right hand touches the left foot and viceversa Receives: Procedure: ACTION OBSERVATION THERAPY |
| Motor Relearning Program Group | Experimental | Motor relearning program based on task oriented training 30mins, 3times/week total 8weeks stage 1, balanced sitting exercises for trunk flexion and rotation, feet and knees 15cm apart multidirectional reaching while seated forward, lateral and diagnol reaching to pick up any thing from different directions butt walking scooting on bed stage 2, standing up and sitting down transition from a seated position on a firm flat surface with no armrests to standing with an upright posture, upper body vertical and feet placed backward followed by sitting down by flexing hips,knees and ankle prerequisited of sit to stand, 4phases in sitting dorsiflexion training, flexion extension training of knee joint right hand touch to left foot and viceversa picking up objects from floor stage3, balanced standing weight shifting head and trunk movemnts while standing with feetapart standing unsupported with eyes closed multidirectional reaching, forward, bakcward, lateral and diagonal Receives: Procedure: MOTOR RELEARNING PROGRAM |
What is being measured
The primary outcome is the main question the study is designed to answer.
Balance
Berg Balance Scale will be used to assess balance
Measured: 8 weeks
anticipatory balance
Modified functional reach test will be used
Measured: 8 weeks
Mobility
The timed up and go test will be used
Measured: 8 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted27 Apr 2025
- Study start22 Jul 2024
- Primary completion20 May 2025 (estimated)
- Study completion15 Jun 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Subacute StrokeStudies of the same condition, open and under way.
- More trials run by Foundation University IslamabadThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 30 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Foundation University Islamabad
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06947343
- Sponsor's protocol ID
- FUI/CTR/2024/66
- Status last verified
- Apr 2025
- First submitted
- 20 Apr 2025
- Last updated
- 27 Apr 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 27 Apr 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Action Observation Therapy in Comparison to Motor Relearning Program on Balance and Mobility Among Subacute Stroke Patients
- ClinicalTrials.gov ID
- NCT06947343
- Acronym / sponsor ID
- FUI/CTR/2024/66
- Keywords
- Action observation therapy, Motor relearning program
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 30 participants (estimated)
- Lead sponsor
- Foundation University IslamabadUniversity, hospital or other
- Study start
- 22 Jul 2024 (actual)
- Primary completion
- 20 May 2025 (estimated)
- Study completion
- 15 Jun 2025 (estimated)
- First posted
- 27 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study is a randomized controlled trial. The purpose of this study is to determine the effect of Action Observation Therapy in Comparison to a Motor Relearning Program on Balance and Mobility among subacute stroke patients.
Detailed description
Action observation therapy has proven its positive effects in improving functional performance in stroke patients compared to other neurological and musculoskeletal conditions motor relearning program is also very effective in improving functional performance in stroke patients but previous studies have shown individual effects of AOT and MRP but there is no comparison of AOT with MRP on balance and mobility.
as a result, this study aims to contribute new data to the sparse literature on subacute stroke patients.
The research finidings could provide valuable insights into potential benefits, encouraging evidence-based practices.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Action Observation Therapy GROUP | Experimental | Procedure: ACTION OBSERVATION THERAPYfunctional AOT with visual feedback and physcial training after watching a video 30mins session, 3times/week total 8weeks 3mins for observation phase, 2min for action execution stage 1, sitting position (static and dynamic balance) exercies for trunk flexion, upper and lower trunk rotation multidirectional reaching to pickup any object from different directions,foward,lateral and diagnol reaching stage 2, sit to stand and stand to sit from sitting to standing, trunk flexed, hips and knees 90 degree flexed, feet behind knee, 15cm apart, then standing, trunk extension hips knees extend feet apart and viceversa 4phases of sit to stand, seat off, standing, seat on, sitting in sitting position dorsiflexion training, flexion extension training knee joint the right hand touches the left foot and viceversa |
| Motor Relearning Program Group | Experimental | Procedure: MOTOR RELEARNING PROGRAMMotor relearning program based on task oriented training 30mins, 3times/week total 8weeks stage 1, balanced sitting exercises for trunk flexion and rotation, feet and knees 15cm apart multidirectional reaching while seated forward, lateral and diagnol reaching to pick up any thing from different directions butt walking scooting on bed stage 2, standing up and sitting down transition from a seated position on a firm flat surface with no armrests to standing with an upright posture, upper body vertical and feet placed backward followed by sitting down by flexing hips,knees and ankle prerequisited of sit to stand, 4phases in sitting dorsiflexion training, flexion extension training of knee joint right hand touch to left foot and viceversa picking up objects from floor stage3, balanced standing weight shifting head and trunk movemnts while standing with feetapart standing unsupported with eyes closed multidirectional reaching, forward, bakcward, lateral and diagonal |
Who may qualify
- Ages
- 45 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (6 listed)
- Both genders, male and female
- Ischemic stroke patients
- Age 45 years and above
- MMSE>24
- Able to stand independently for 1 minute
Key exclusion criteria (3 listed)
- Any other neurological disorder
- Orthopedic conditions(fracture) affecting balance and mobility
- Visual or auditory impairments
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| ACTION OBSERVATION THERAPYfunctional AOT with visual feedback and physical training after watching a video 30mins session, 3times/week total 8weeks 3mins for observation phase, 2min for action execution Stage 1, sitting position (static and dynamic balance) exercises for trunk flexion, upper and lower trunk rotation multidirectional reaching to pick up any object from different directions, forward, lateral, and diagonal reaching Stage 2, sit to stand and stand to sit from sitting to standing, trunk flexed, hips and knees 90 degree flexed, feet behind knee, 15cm apart, then standing, trunk extension hips knees extend feet apart and vice vers 4phases of sit to stand, seat off, standing, seat on, sitting in sitting position dorsiflexion training, flexion extension training knee joint the right hand touches the left foot and viceversa pick up an object from floor stage3, standing balance weight shifting, front, back, sideways, left and right head and trunk movements in different directions while standing | Procedure or surgery | Action Observation Therapy GROUP |
| MOTOR RELEARNING PROGRAMMotor relearning program, interventional group B, based on task-oriented training 30mins, 3times/week total 8weeks stage 1, balanced sitting exercises for trunk flexion and rotation, feet and knees 15cm apart multidirectional reaching while seated forward, lateral and diagonal reaching to pick up any thing from different directions butt walking scooting on bed stage 2, standing up and sitting down transition from a seated position on a firm flat surface with no armrests to standing with an upright posture, upper body vertical and feet placed backward followed by sitting down by flexing hips,knees and ankle prerequisited of sit to stand, 4phases in sitting dorsiflexion training, flexion extension training of knee joint right hand touch to left foot and viceversa picking up objects from floor stage3, balanced standing weight shifting head and trunk movemnts while standing with feetapart standing unsupported with eyes closed multidirectional reaching | Procedure or surgery | Motor Relearning Program Group |
Primary outcome
Balance
Time frame: 8 weeks
Berg Balance Scale will be used to assess balance
anticipatory balance
Time frame: 8 weeks
Modified functional reach test will be used
Mobility
Time frame: 8 weeks
The timed up and go test will be used
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 27 Apr 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing ACTION OBSERVATION THERAPY and MOTOR RELEARNING PROGRAM in people with Subacute Stroke and Cerebral Stroke, run by Foundation University Islamabad at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 6 inclusion and 3 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 27 Apr 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Nabiha Tahir, DPT (+92 3001522237, biya.tahir2920@gmail.com), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Balance (time frame: 8 weeks). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 27 Apr 2025.