Healty VolunteersNCT06951048
The Role of Lower Limb Neural Mobilization in Improving Balance and Performance
A study testing Group I (Neural Mobilization), Group II (Neural Mobilization + Dynamic Stretching) and Group III (Dynamic Stretching Only) in people with Healty Volunteers and Sedantary, run by Uludag University at 1 site in Turkey (Türkiye).
Trial summary
Neural mobilization (NM) is a technique used to enhance the mobility of peripheral nerves relative to surrounding tissues, aiming to reduce physiological tension and improve movement quality. Read more about this study
- Who is it for?
- Ages 18 to 30 years, women onlyHealthy volunteers can take part
- Conditions the study is for
- Healty Volunteers, Sedantary, Young
- What is being tested?
- Group I (Neural Mobilization), Group II (Neural Mobilization + Dynamic Stretching) and Group III (Dynamic Stretching Only)
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 60 participants
- Where
- 1 siteTurkey (Türkiye)
- Study dates
- 1 Mar 2025to 1 Jul 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 30 years
- Women only
- Healthy volunteers accepted
- Adult
Who may be able to join
- Providing written informed consent to voluntarily participate in the study
- Being a female individual aged between 18 and 30 years
- Having no medical conditions that contraindicate participation in physical exercise
Who cannot join
- Presence of structural spinal deformities such as scoliosis
- History of lumbar or lower extremity surgery within the past 12 months
- Experience of localized pain in the lumbar or lower extremity regions within the past 3 months
- Diagnosis of any neurodegenerative or neuromuscular disorders
- Presence of any medical condition that may hinder or contraindicate safe participation in exercise interventions
Trial locations and contacts
1 site in 1 country.
About this study
Official title: The Effects of Lower Extremity Neural Mobilization Techniques on Muscle Strength and Performance in Healthy Individuals
Neural mobilization (NM) is a technique used to enhance the mobility of peripheral nerves relative to surrounding tissues, aiming to reduce physiological tension and improve movement quality. While its effects are well-documented in clinical populations, recent studies have explored its use in healthy individuals to improve flexibility, balance, and functional performance. Evidence supports its positive impact on hamstring flexibility; however, findings on balance and performance remain inconclusive. This study aims to examine the effects of lower extremity NM techniques on balance, flexibility, and functional performance in healthy individuals, addressing current gaps in the literature.
Read the detailed description
Neural Mobilization (NM) is a therapeutic approach based on the movement of neural structures, applied either manually or through exercise. Neural tissue is mobilized relative to adjacent structures to reduce symptoms through mechanisms that may be mechanical or neurophysiological. The nervous system separates itself from surrounding tissues by considering its own mobility and the relationship with adjacent structures. NM can be applied through various stretching and mobilization maneuvers to either facilitate movement or maximize the sliding (gliding) of peripheral nerves relative to adjacent tissues.
Studies on both humans and animals have reported that NM reduces intraneural edema, improves intraneural fluid distribution, decreases thermal and mechanical hyperalgesia, and reverses increased immune responses. Although NM is commonly used to improve the functionality of neural structures and alleviate symptoms associated with disease, recent research has explored its application in asymptomatic individuals to influence flexibility and performance parameters and to prevent injuries.
Nunes et al. investigated changes in functional performance and balance parameters by applying lower extremity nerve mobilization to asymptomatic individuals. Their study concluded that a single session of NM (including both stretching and mobilization) applied to the sciatic, tibial, and femoral nerves in healthy subjects resulted in no significant changes in performance, suggesting that the dosage and duration of NM may influence the outcomes.
In their study examining the acute effects of neural gliding exercises on athletic performance in healthy individuals, Waldhelm et al. found that bilateral sciatic nerve gliding exercises did not outperform a dynamic stretching protocol in terms of performance. However, they reported a greater improvement in hamstring flexibility. Based on these findings, they suggested that incorporating NM into warm-up routines may help prevent injuries. Similarly, Sharma et al. stated that adding neural stretching or mobilization to static stretching contributed more to hamstring flexibility than static stretching alone, although no dynamic performance assessment was included in the study.
Another study investigated the effects of neurodynamic glide techniques on hamstring flexibility in healthy male football players aged. The results showed that the neurodynamic intervention group experienced significant improvements in hamstring flexibility one week later compared to the control group.
D'souza et al. evaluated the short-term effects of different neural mobilization techniques on hamstring flexibility in recreational football players. While both the neural stretching and neural mobilization groups showed significant improvements, there was no significant difference between the groups in terms of sit-and-reach and active knee extension test results.
Ferrera et al. investigated the acute effects of neural gliding and neural tensioning exercises on static postural control and jumping performance in football players. Both techniques resulted in significant improvements in measured parameters, though no significant differences were observed between the techniques. The positive effects were reported to last for approximately 30 minutes.
Although literature suggests that NM techniques contribute to flexibility in asymptomatic individuals, their effects on functional performance, balance, and posture remain controversial. Furthermore, the limited number of studies conducted on healthy populations and methodological variations in existing research create uncertainty regarding the efficacy of NM techniques. Therefore, there is a need for studies that examine the effects of application dosage and duration and contribute to the understanding of NM.
The aim of this study is to investigate the effects of lower extremity neural mobilization techniques on balance, flexibility, and functional performance in healthy individuals.
- Conditions
- Healty Volunteers, Sedantary, Young, Female
- Being tested
- Group I (Neural Mobilization), Group II (Neural Mobilization + Dynamic Stretching), Group III (Dynamic Stretching Only)
- Keywords
- Neural Mobilisation, Performance, Balance, Reactive agility
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Group I (Neural Mobilization)Other
Participants will undergo a neural mobilization program targeting the sciatic, femoral, and tibial nerves. Exercises are designed to promote nerve sliding through specific movement patterns and are performed bilaterally. Each nerve mobilization is applied in 4 sets of 10 repetitions, three times per week on non-consecutive days, with 30-second rest intervals.
Sciatic nerve: Performed in side-lying; ankle dorsiflexion with neck extension followed by dorsiflexion release and neck flexion.
Femoral nerve: In side-lying; simultaneous movements of the hip, knee, and neck in flexion and extension.
Tibial nerve: In supine; coordinated ankle, toe, and cervical spine movements with controlled hip/knee positioning.
Group II (Neural Mobilization + Dynamic Stretching)Other
Participants in this group will engage in the same neural mobilization protocol applied in Group I, combined with a structured dynamic stretching program targeting lower extremity flexibility and neuromuscular performance. The dynamic exercises include active straight leg raises (SLR), vertical jumps, and 10-meter sprints. Each activity will be performed in three sets of ten repetitions, aiming to enhance muscular activation, mobility, and functional readiness.
Group III (Dynamic Stretching Only)Other
This group will engage exclusively in a dynamic stretching protocol comprising active straight leg raises (SLR), vertical jump exercises, and 10-meter sprint drills. Each exercise will be performed in three sets of ten repetitions, focusing on enhancing lower extremity mobility, muscle activation, and functional movement capacity without any neural mobilization intervention.
| Study group | Role | What they receive |
|---|---|---|
| Group I (Neural Mobilization) | Experimental | This group will follow a neural mobilization protocol targeting the sciatic, femoral, and tibial nerves. Neural exercises will be applied using specific techniques to facilitate nerve sliding along its anatomical path. Each nerve mobilization will be performed in 4 sets of 10 repetitions, three times a week (non-consecutive days). Receives: Other: Group I (Neural Mobilization) |
| Group II (Neural Mobilization + Dynamic Stretching) | Active comparator | This group will perform the same neural mobilization protocol as Group I, in addition to dynamic stretching exercises targeting the lower extremities. The dynamic stretching program includes active straight leg raises (SLR), vertical jumps, and 10-meter sprints, performed in 3 sets of 10 repetitions for each exercise. Receives: Other: Group II (Neural Mobilization + Dynamic Stretching) |
| Group III (Dynamic Stretching Only) | Active comparator | This group will follow a dynamic stretching protocol consisting of the same SLR, vertical jump, and 10-meter sprint exercises, performed in 3 sets of 10 repetitions. Receives: Other: Group III (Dynamic Stretching Only) |
What is being measured
The primary outcome is the main question the study is designed to answer.
Reactive Agility Test
Y-shaped course will be set up using three cones spaced 2 meters apart. Participants start by sprinting from the starting line; at the middle cone, a test administrator will randomly direct them to run left or right toward the finish line. Time will be recorded from the start to finish, and the best of three trials will be used for analysis.
Measured: Baseline and at Week 2
Y Balance Test
This test assesses balance and stability. Participants will reach in three directions: anterior, 135° posteromedial, and 135° posterolateral using a prepared setup. After six practice attempts per direction, three test trials will be recorded, and the best score will be used. Lower limb length will be measured from the anterior superior iliac spine to the medial malleolus.
Measured: Baseline and at Week 2
Active Straight Leg Raise Test
Used to assess hamstring flexibility. The test leg is lifted straight (without knee flexion) three times, and the highest angle of hip flexion measured with a goniometer will be recorded.
Measured: Baseline and at Week 2
Muscle Strength
Isometric strength of the lower extremity will be measured using the Lafayette Manual Muscle Testing System Model-01165 (Lafayette Instrument Company, Lafayette IN, USA). Maximum isometric contraction will be measured in both knee flexion and extension with participants seated at 90° hip and knee flexion. Each contraction will last 5 seconds, repeated three times, and the average value will be used.
Measured: Baseline and at Week 2
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted30 Apr 2025
- Study start1 Mar 2025
- Primary completion1 Jun 2025
- Study completion1 Jul 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (5)Papers the sponsor has linked to this study.
- Other trials for Healty VolunteersStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind
- Who is masked
- Participant, Investigator
- Enrolment
- 60 participants (actual)
Sponsor and investigators
- Lead sponsor
- Uludag University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Selim Mahmut GÜNAY, Uludag University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06951048
- Sponsor's protocol ID
- 2025/4-1
- Status last verified
- Jul 2025
- First submitted
- 22 Apr 2025
- Last updated
- 9 Jul 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No: Individual participant data (IPD) will not be shared due to concerns regarding participant privacy and limitations in the informed consent obtained from participants
Publications
Castellote-Caballero Y, Valenza MC, Martin-Martin L, Cabrera-Martos I, Puentedura EJ, Fernandez-de-Las-Penas C. Effects of a neurodynamic sliding technique on hamstring flexibility in healthy male soccer players. A pilot study. Phys Ther Sport. 2013 Aug;14(3):156-62. doi: 10.1016/j.ptsp.2012.07.004. Epub 2012 Nov 8.
PubMed 23142014Waldhelm A, Gacek M, Davis H, Saia C, Kirby B. ACUTE EFFECTS OF NEURAL GLIDING ON ATHLETIC PERFORMANCE. Int J Sports Phys Ther. 2019 Jul;14(4):603-612.
PubMed 31440411Ferreira J, Bebiano A, Raro D, Martins J, Silva AG. Comparative Effects of Tensioning and Sliding Neural Mobilization on Static Postural Control and Lower Limb Hop Testing in Football Players. J Sport Rehabil. 2019 Nov 1;28(8):840-846. doi: 10.1123/jsr.2017-0374.
PubMed 30222495Heredia Macias C, Paredes Hernandez V, Fernandez Seguin LM. A systematic review of the efficacy of neural mobilisation in sport: A tool for the neural tension assessment. J Bodyw Mov Ther. 2024 Oct;40:1409-1416. doi: 10.1016/j.jbmt.2023.04.034. Epub 2023 Apr 17.
PubMed 39593463Gunay SM, Erturk E. Effects of lower limb neural mobilisation on reactive agility, balance, and physical performance: a randomised controlled trial. BMC Sports Sci Med Rehabil. 2025 Dec 10;18(1):1. doi: 10.1186/s13102-025-01461-3.
PubMed 41372947
Study at a glance
From the registry record, last updated by the sponsor on 9 Jul 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- The Effects of Lower Extremity Neural Mobilization Techniques on Muscle Strength and Performance in Healthy Individuals
- ClinicalTrials.gov ID
- NCT06951048
- Acronym / sponsor ID
- 2025/4-1
- Conditions
- Healty Volunteers, Sedantary, Young, Female
- Keywords
- Neural Mobilisation, Performance, Balance, Reactive agility
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 60 participants (actual)
- Lead sponsor
- Uludag UniversityUniversity, hospital or other
- Study start
- 1 Mar 2025 (actual)
- Primary completion
- 1 Jun 2025 (actual)
- Study completion
- 1 Jul 2025 (actual)
- First posted
- 30 Apr 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Neural mobilization (NM) is a technique used to enhance the mobility of peripheral nerves relative to surrounding tissues, aiming to reduce physiological tension and improve movement quality. While its effects are well-documented in clinical populations, recent studies have explored its use in healthy individuals to improve flexibility, balance, and functional performance. Evidence supports its positive impact on hamstring flexibility; however, findings on balance and performance remain inconclusive. This study aims to examine the effects of lower extremity NM techniques on balance, flexibility, and functional performance in healthy individuals, addressing current gaps in the literature.
Detailed description
Neural Mobilization (NM) is a therapeutic approach based on the movement of neural structures, applied either manually or through exercise. Neural tissue is mobilized relative to adjacent structures to reduce symptoms through mechanisms that may be mechanical or neurophysiological. The nervous system separates itself from surrounding tissues by considering its own mobility and the relationship with adjacent structures. NM can be applied through various stretching and mobilization maneuvers to either facilitate movement or maximize the sliding (gliding) of peripheral nerves relative to adjacent tissues.
Studies on both humans and animals have reported that NM reduces intraneural edema, improves intraneural fluid distribution, decreases thermal and mechanical hyperalgesia, and reverses increased immune responses. Although NM is commonly used to improve the functionality of neural structures and alleviate symptoms associated with disease, recent research has explored its application in asymptomatic individuals to influence flexibility and performance parameters and to prevent injuries.
Nunes et al. investigated changes in functional performance and balance parameters by applying lower extremity nerve mobilization to asymptomatic individuals. Their study concluded that a single session of NM (including both stretching and mobilization) applied to the sciatic, tibial, and femoral nerves in healthy subjects resulted in no significant changes in performance, suggesting that the dosage and duration of NM may influence the outcomes.
In their study examining the acute effects of neural gliding exercises on athletic performance in healthy individuals, Waldhelm et al. found that bilateral sciatic nerve gliding exercises did not outperform a dynamic stretching protocol in terms of performance. However, they reported a greater improvement in hamstring flexibility. Based on these findings, they suggested that incorporating NM into warm-up routines may help prevent injuries. Similarly, Sharma et al. stated that adding neural stretching or mobilization to static stretching contributed more to hamstring flexibility than static stretching alone, although no dynamic performance assessment was included in the study.
Another study investigated the effects of neurodynamic glide techniques on hamstring flexibility in healthy male football players aged. The results showed that the neurodynamic intervention group experienced significant improvements in hamstring flexibility one week later compared to the control group.
D'souza et al. evaluated the short-term effects of different neural mobilization techniques on hamstring flexibility in recreational football players. While both the neural stretching and neural mobilization groups showed significant improvements, there was no significant difference between the groups in terms of sit-and-reach and active knee extension test results.
Ferrera et al. investigated the acute effects of neural gliding and neural tensioning exercises on static postural control and jumping performance in football players. Both techniques resulted in significant improvements in measured parameters, though no significant differences were observed between the techniques. The positive effects were reported to last for approximately 30 minutes.
Although literature suggests that NM techniques contribute to flexibility in asymptomatic individuals, their effects on functional performance, balance, and posture remain controversial. Furthermore, the limited number of studies conducted on healthy populations and methodological variations in existing research create uncertainty regarding the efficacy of NM techniques. Therefore, there is a need for studies that examine the effects of application dosage and duration and contribute to the understanding of NM.
The aim of this study is to investigate the effects of lower extremity neural mobilization techniques on balance, flexibility, and functional performance in healthy individuals.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (participant, investigator)
- Number of arms
- 3
| Arm | Type | Receives |
|---|---|---|
| Group I (Neural Mobilization) | Experimental | Other: Group I (Neural Mobilization)This group will follow a neural mobilization protocol targeting the sciatic, femoral, and tibial nerves. Neural exercises will be applied using specific techniques to facilitate nerve sliding along its anatomical path. Each nerve mobilization will be performed in 4 sets of 10 repetitions, three times a week (non-consecutive days). |
| Group II (Neural Mobilization + Dynamic Stretching) | Active comparator | Other: Group II (Neural Mobilization + Dynamic Stretching)This group will perform the same neural mobilization protocol as Group I, in addition to dynamic stretching exercises targeting the lower extremities. The dynamic stretching program includes active straight leg raises (SLR), vertical jumps, and 10-meter sprints, performed in 3 sets of 10 repetitions for each exercise. |
| Group III (Dynamic Stretching Only) | Active comparator | Other: Group III (Dynamic Stretching Only)This group will follow a dynamic stretching protocol consisting of the same SLR, vertical jump, and 10-meter sprint exercises, performed in 3 sets of 10 repetitions. |
Who may qualify
- Ages
- 18 to 30 years
- Sex
- Female only
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (3 listed)
- Providing written informed consent to voluntarily participate in the study
- Being a female individual aged between 18 and 30 years
- Having no medical conditions that contraindicate participation in physical exercise
Key exclusion criteria (5 listed)
- Presence of structural spinal deformities such as scoliosis
- History of lumbar or lower extremity surgery within the past 12 months
- Experience of localized pain in the lumbar or lower extremity regions within the past 3 months
- Diagnosis of any neurodegenerative or neuromuscular disorders
- Presence of any medical condition that may hinder or contraindicate safe participation in exercise interventions
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Group I (Neural Mobilization)Participants will undergo a neural mobilization program targeting the sciatic, femoral, and tibial nerves. Exercises are designed to promote nerve sliding through specific movement patterns and are performed bilaterally. Each nerve mobilization is applied in 4 sets of 10 repetitions, three times per week on non-consecutive days, with 30-second rest intervals. Sciatic nerve: Performed in side-lying; ankle dorsiflexion with neck extension followed by dorsiflexion release and neck flexion. Femoral nerve: In side-lying; simultaneous movements of the hip, knee, and neck in flexion and extension. Tibial nerve: In supine; coordinated ankle, toe, and cervical spine movements with controlled hip/knee positioning. | Other | Group I (Neural Mobilization) |
| Group II (Neural Mobilization + Dynamic Stretching)Participants in this group will engage in the same neural mobilization protocol applied in Group I, combined with a structured dynamic stretching program targeting lower extremity flexibility and neuromuscular performance. The dynamic exercises include active straight leg raises (SLR), vertical jumps, and 10-meter sprints. Each activity will be performed in three sets of ten repetitions, aiming to enhance muscular activation, mobility, and functional readiness. | Other | Group II (Neural Mobilization + Dynamic Stretching) |
| Group III (Dynamic Stretching Only)This group will engage exclusively in a dynamic stretching protocol comprising active straight leg raises (SLR), vertical jump exercises, and 10-meter sprint drills. Each exercise will be performed in three sets of ten repetitions, focusing on enhancing lower extremity mobility, muscle activation, and functional movement capacity without any neural mobilization intervention. | Other | Group III (Dynamic Stretching Only) |
Primary outcome
Reactive Agility Test
Time frame: Baseline and at Week 2
Y-shaped course will be set up using three cones spaced 2 meters apart. Participants start by sprinting from the starting line; at the middle cone, a test administrator will randomly direct them to run left or right toward the finish line. Time will be recorded from the start to finish, and the best of three trials will be used for analysis.
Y Balance Test
Time frame: Baseline and at Week 2
This test assesses balance and stability. Participants will reach in three directions: anterior, 135° posteromedial, and 135° posterolateral using a prepared setup. After six practice attempts per direction, three test trials will be recorded, and the best score will be used. Lower limb length will be measured from the anterior superior iliac spine to the medial malleolus.
Active Straight Leg Raise Test
Time frame: Baseline and at Week 2
Used to assess hamstring flexibility. The test leg is lifted straight (without knee flexion) three times, and the highest angle of hip flexion measured with a goniometer will be recorded.
Muscle Strength
Time frame: Baseline and at Week 2
Isometric strength of the lower extremity will be measured using the Lafayette Manual Muscle Testing System Model-01165 (Lafayette Instrument Company, Lafayette IN, USA). Maximum isometric contraction will be measured in both knee flexion and extension with participants seated at 90° hip and knee flexion. Each contraction will last 5 seconds, repeated three times, and the average value will be used.
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 9 Jul 2025.
- Results publication: PubMed 23142014Castellote-Caballero Y, Valenza MC, Martin-Martin L, Cabrera-Martos I, Puentedura EJ, Fernandez-de-Las-Penas C. Effects of a neurodynamic sliding technique on hamstring flexibility in healthy male soccer players. A pilot study. Phys Ther Sport. 2013 Aug;14(3):156-62. doi: 10.1016/j.ptsp.2012.07.004. Epub 2012 Nov 8.
- Results publication: PubMed 31440411Waldhelm A, Gacek M, Davis H, Saia C, Kirby B. ACUTE EFFECTS OF NEURAL GLIDING ON ATHLETIC PERFORMANCE. Int J Sports Phys Ther. 2019 Jul;14(4):603-612.
- Results publication: PubMed 30222495Ferreira J, Bebiano A, Raro D, Martins J, Silva AG. Comparative Effects of Tensioning and Sliding Neural Mobilization on Static Postural Control and Lower Limb Hop Testing in Football Players. J Sport Rehabil. 2019 Nov 1;28(8):840-846. doi: 10.1123/jsr.2017-0374.
- Results publication: PubMed 39593463Heredia Macias C, Paredes Hernandez V, Fernandez Seguin LM. A systematic review of the efficacy of neural mobilisation in sport: A tool for the neural tension assessment. J Bodyw Mov Ther. 2024 Oct;40:1409-1416. doi: 10.1016/j.jbmt.2023.04.034. Epub 2023 Apr 17.
- Derived from this study: PubMed 41372947Gunay SM, Erturk E. Effects of lower limb neural mobilisation on reactive agility, balance, and physical performance: a randomised controlled trial. BMC Sports Sci Med Rehabil. 2025 Dec 10;18(1):1. doi: 10.1186/s13102-025-01461-3.
- Related InfoLink provided by the sponsor.
- Individual participant dataSharing planned: No. Individual participant data (IPD) will not be shared due to concerns regarding participant privacy and limitations in the informed consent obtained from participants
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Group I (Neural Mobilization), Group II (Neural Mobilization + Dynamic Stretching) and Group III (Dynamic Stretching Only) in people with Healty Volunteers and Sedantary, run by Uludag University at 1 site in Turkey (Türkiye).
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 9 Jul 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Turkey (Türkiye). Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Reactive Agility Test (time frame: Baseline and at Week 2). The study lists 4 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06951048, which also lists 5 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 9 Jul 2025.