AzTrials
AzTrials

Developmental Language DisorderNCT06954194

Syntactic Intervention for Cantonese-speaking Children With DLD

A study testing Explicit intervention (Shape Coding+syntactic priming) and Implicit intervention (syntactic priming only) in people with Developmental Language Disorder, run by The Hong Kong Polytechnic University at 1 site in Hong Kong.

Recruiting

Looking for participants now. Contact the study team or a site below to ask about taking part.

Sites and contacts
Official record
Search all trials

Trial summary

The goal of this clinical trial is to compare the efficacy of explicit vs. implicit intervention on subject relative clause production in Cantonese-speaking children with Developmental Language Disorder (DLD). It will also learn about individual difference predictors of intervention outcomes. Read more about this study

Who is it for?
Ages 5 to 8 years
Conditions the study is for
Developmental Language Disorder
What is being tested?
Explicit intervention (Shape Coding+syntactic priming) and Implicit intervention (syntactic priming only)
Could I receive a placebo?
No, everyone receives an active treatment
How many people
32 participants
Where
1 siteHong Kong
Study dates
10 Feb 2024to May 2026
Phase
Interventional
Are there results?
Not yet: the study is under way

Key requirements

Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.

  • Ages 5 to 8 years
  • All sexes
  • No healthy volunteers
  • Child

Who may be able to join

  • being Cantonese dominant who learned Cantonese as their first language and attending Cantonese-medium primary schools.
  • having normal IQ and no hearing impairment.
  • scoring at least -1.25 SD below the mean in any two subtests of the Hong Kong Cantonese Oral Language Assessment Scale (a standardized language assessment tool for Hong Kong Cantonese-speaking children).

Who cannot join

  • Autism Spectrum Disorder.

Trial locations and contacts

1 site in 1 country. Contact the study team or a site near you to ask about taking part.

Hong Kong1 site, 1 recruiting
  • Speech and Language Sciences Laboratory (SLS Lab)

    Hong Kong

    Albert Chau, 85227664271, albert.chau@polyu.edu.hk

    Recruiting

Other trials in Hong Kong

About this study

Official title: The Efficacy of Explicit vs. Implicit Intervention Procedures for Cantonese Children With Developmental Language Disorder: A Randomized Controlled Trial

The goal of this clinical trial is to compare the efficacy of explicit vs. implicit intervention on subject relative clause production in Cantonese-speaking children with Developmental Language Disorder (DLD). It will also learn about individual difference predictors of intervention outcomes. The main questions it aims to answer are:

  1. Will the explicit intervention (Shape Coding+syntactic priming) on relative clause production lead to better outcomes than implicit intervention (syntactic priming only)?
  2. Can pre-intervention procedural learning, working memory (WM) capacities, and grammar impairment severity predict the intervention outcomes across children with DLD?
  3. Will 10 intervention sessions (500 doses of the target structure) lead to learning progress in children with DLD, even with implicit intervention, and will the progress plateau at some point of the intervention?
Read more

Researchers will compare the explicit intervention to the implicit intervention to see if the explicit intervention leads to better interventional outcomes.

Participants will:

  • Undergo diagnostic assessments of DLD to confirm their DLD status.
  • Complete pre-intervention assessments to assess their procedural learning and working memory capacities.
  • Undergo the intervention phase, which consists of a pretest, 10 intervention sessions, three posttests (after the 1st, 5th and 10th intervention), and a retention test (1 month after the last intervention).
Read the detailed description

This project is the first to adopt a randomized controlled trial (RCT) to compare the efficacy of explicit vs. implicit intervention on relative clause production (subject relative clause in object position of the main clause or SRC-O) in Cantonese-speaking children with DLD and to use an individual difference approach to identify predictors of intervention outcomes.

The investigators aim to examine the following three specific questions:

  1. Will the explicit intervention (Shape Coding+syntactic priming) on relative clause production lead to better outcomes than implicit intervention (syntactic priming only)? Based on the Procedural circuit Deficit Hypothesis (PDH), the investigators hypothesize that explicit intervention would switch the reliance of learning to the relatively intact declarative learning circuitry and lead to better outcomes than implicit intervention.
  2. Can pre-intervention procedural learning, working memory (WM) capacities, and grammar impairment severity predict the intervention outcomes across children with DLD? Based on the PDH, the investigators hypothesize that children with lower procedural learning abilities will demonstrate worse outcomes in the implicit intervention group, but better outcomes in the explicit intervention group. As for WM and grammar impairment, the investigators hypothesize that children with better WM or grammatical abilities will demonstrate better outcomes in both groups.
  3. Will 10 intervention sessions (500 doses of the target structure) lead to learning progress in children with DLD, even with implicit intervention, and will the progress plateau at some point of the intervention? As informed by previous studies, the investigators hypothesize that more exposure to the target structure, especially with high variability in the input, will lead to improvement, even for the implicit intervention group. The investigators will explore whether the progress will plateau over the course of interventions and compare the learning trajectory between explicit and implicit interventions.

A total of 32 Cantonese-speaking school-age children with DLD (5-8 years old) will be recruited (N=16/group). The children will be pre-screened with an online questionnaire on language background and case history, and then assessed on the Raven's Standard Progressive Matrices (~25 min), hearing screening (~5 min) and Hong Kong Cantonese Oral Language Assessment Scale (HKCOLAS) (~90 min) to confirm DLD. Eligible children will be assigned to one of the two intervention groups following a random allocation sequence of letters "A" and "B" (e.g., ABBBA…), where A and B refer to the explicit and implicit intervention respectively, on a 1:1 allocation ratio.

The study consists of pre-intervention assessments and an intervention phase. For pre-intervention assessments, children's procedural learning, declarative learning, and working memory capacities will be assessed using the serial reaction time (SRT) task, old/new picture recognition task, and forward and backward digit span test, respectively. The purpose is to examine the predictive power of these capacities in the individual children's intervention outcomes.

The intervention phase includes a pretest, 10 intervention sessions, three posttests (after the 1st, 5th and 10th intervention), and a retention test (1 month after the last intervention). The pretest serves as a baseline; the three posttests are to assess maintenance of the target structure (SRC-O) after priming has ceased and the improvement over the course of interventions; the retention test is for assessing longer-term retention of the intervention outcomes.

The procedure of the pretest, three posttests and retention (~10 min/test) is identical, during which the children will be asked to describe 10 pictures without priming or feedback from the experimenter. Ten online intervention sessions (~45 min/session) will be administered to the children via zoom over four weeks, with 2-3 sessions per week.

For explicit intervention, a syntactic priming task will be preceded by explicit teaching of the target structure using the Shape Coding scheme adapted to be age- and language (Cantonese)-appropriate. A different set of 10 sentences will be used for teaching in each explicit intervention session, with five sentences used as exemplars for the experimenter to explain the target structure, and the remaining five sentences for children to practice. During the practice, the children will be asked to drag words into their corresponding shapes (e.g., oval for noun/noun phrase, rhombus for verb/verb phrase, and square for particle). All sentences will be constructed using the P1 Chinese character database to ensure that children can read the sentences.

The syntactic priming session will be presented as a game to sustain the children's interest and to disguise the purpose of the study. Each intervention session will contain 40 pairs of prime-target pictures, 40 pairs of control-target pictures, and 20 pairs of filler pictures, randomly presented to the experimenter and child and controlled by the experimenter. The game rule is to catch when two identical pictures are presented to the experimenter and child (i.e., fillers) by saying "Snap!". For each prime/control-target pair, the experimenter will describe a picture using the target structure - subject relative clause in object position of the main clause (SRC-O), and the child will produce a sentence based on the second picture. In total, there are 500 doses of SRC-O sentences (50 sentences x10 sessions).

For implicit intervention, the same 10 sessions of syntactic priming will be provided to the children without explicit instruction of the SRC-O structure using the Shape Coding System. Nonetheless, to make the exposure and dosage as comparable as possible between the two groups, children in the implicit intervention group will also receive 10 listening sessions before the syntactic priming sessions. During the listening sessions, the same sets of sentences used in the explicit instruction sessions will be presented and the children will be instructed to listen closely as the tutor reads aloud the SRC-O sentence. Each listening session will be followed by a syntactic priming session that is identical to that of the explicit intervention group. In total, there are also 500 doses of SRC-O sentences (50 sentences x10 sessions).

Being tested
Explicit intervention (Shape Coding+syntactic priming), Implicit intervention (syntactic priming only)
Keywords
Randomized Controlled Trial, Explicit intervention, Implicit intervention, Procedural circuit Deficit Hypothesis, Individual difference, Relative clause, Syntactic priming, Shape coding
Medical subject headings
Language Development Disorders

What participants receive

What participants receive. In a randomised study each person is assigned to one group by chance.

  • Explicit intervention (Shape Coding+syntactic priming)Behavioural

    For explicit intervention, a syntactic priming task will be preceded by explicit teaching of the target structure using the Shape Coding scheme adapted to be age- and language (Cantonese)-appropriate. A different set of 10 sentences will be used for teaching in each explicit intervention session, with five sentences used as exemplars for the experimenter to explain the target structure, and the remaining five sentences for children to practice. The syntactic priming session will be presented as a game to sustain the children's interest and to disguise the purpose of the study. Each intervention session will contain 40 pairs of prime-target pictures, 40 pairs of control-target pictures, and 20 pairs of filler pictures, randomly presented to the experimenter and child and controlled by the experimenter. In total, there are 500 doses of SRC-O sentences (50 sentences x10 sessions).

  • Implicit intervention (syntactic priming only)Behavioural

    For implicit intervention, the same 10 sessions of syntactic priming will be provided to the children without explicit instruction of the SRC-O structure using the Shape Coding System. Nonetheless, to make the exposure and dosage as comparable as possible between the two groups, children in the implicit intervention group will also receive 10 listening sessions before the syntactic priming sessions. During the listening sessions, the same sets of sentences used in the explicit instruction sessions will be presented and the children will be instructed to listen closely as the tutor reads aloud the SRC-O sentence. Each listening session will be followed by a syntactic priming session that is identical to that of the explicit intervention group. In total, there are also 500 doses of SRC-O sentences (50 sentences x10 sessions).

Study groups in NCT06954194
Study groupRoleWhat they receive
Explicit intervention groupExperimentalParticipants in this group will receive explicit teaching of the target structure using the Shape Coding scheme adapted to be age- and language (Cantonese)-appropriate, followed by syntactic priming sessions.
Receives: Behavioral: Explicit intervention (Shape Coding+syntactic priming)
Implicit intervention groupActive comparatorParticipants in this arm will receive identical syntactic priming sessions to the explicit intervention group, but without explicit teaching of the target structure using the Shape Coding scheme.
Receives: Behavioral: Implicit intervention (syntactic priming only)

What is being measured

The primary outcome is the main question the study is designed to answer.

  1. Production accuracy

    Production accuracy of the target structure

    Measured: From pretest to the retention test (1 month after all 10 intervention sessions are completed)

  2. Number of successful learners

    The number of successful learners (≥80% accuracy)

    Measured: From pretest to the retention test (1 month after all 10 intervention sessions are completed)

Timeline

From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.

  1. First posted1 May 2025
  2. Study start10 Feb 2024
  3. Primary completionMay 2026 (estimated)
  4. Study completionMay 2026 (estimated)

Resources

More details

For doctors and researchers: how the study is designed, who runs it, and its registry IDs.

Study design
Study type
Interventional
Phase
Phase N/A
Primary purpose
Treatment
Allocation
Randomised
Intervention model
Parallel groups
Masking
Single blind
Who is masked
Outcomes assessor
Enrolment
32 participants (estimated)
IDs, dates and publications
ClinicalTrials.gov ID
NCT06954194
Sponsor's protocol ID
HSEARS20220505001-02
Other IDs
20211061
Status last verified
Apr 2025
First submitted
24 Apr 2025
Last updated
4 May 2025
Results posted
No
Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
Individual data sharing
Undecided

Questions about this trial

What is this clinical trial studying?

A study testing Explicit intervention (Shape Coding+syntactic priming) and Implicit intervention (syntactic priming only) in people with Developmental Language Disorder, run by The Hong Kong Polytechnic University at 1 site in Hong Kong.

The full registered description is in the About this study section and the official record.

Who may be eligible to take part?

The sponsor lists 3 inclusion and 1 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.

Is this clinical trial currently recruiting?

The record says: looking for participants now, as of the sponsor's last update on 4 May 2025. Status can change between updates, so confirm with the study contact before making plans.

Where is the study taking place?

The record lists 1 site in Hong Kong. Whether a site is taking part right now should be confirmed with that site. See every site.

What are the possible benefits and risks?

They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.

Are results available for this study?

This study is still under way. Results are not available in the source record yet.

How can a doctor refer a patient or contact the research team?

Contact Tracy Tang (852 34008541, tracy-wh.tang@polyu.edu.hk), or a site near the patient. AzTrials does not enrol participants or take referrals.

What does the primary outcome measure?

Production accuracy (time frame: From pretest to the retention test (1 month after all 10 intervention sessions are completed)). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.

Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?

No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.

How often is this information updated?

AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 4 May 2025.

Free account

Log in to keep searching

You’ve used your 3 free searches. AzTrials is free: log in or create a free account to keep searching clinical trials and save the ones you want to follow.

Create a free accountLog in