Virtual RealityReminiSOMMENCT06960915
Efficacy of Virtual Reality Reminiscence Therapy in Nursing Home Residents With Alzheimer's Disease or Related Diseases
A study testing immersive virtual reality and classic reminiscence workshops in people with Virtual Reality and Reminiscence Therapy, run by Centre Hospitalier Universitaire, Amiens at 1 site in France.
Trial summary
This project provides the easiest possible access to heritage elements that older persons with Alzheimer's disease or related diseases knew well but to which they no longer have access due to the motor and functional dependencies they present. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Virtual Reality, Reminiscence Therapy, Nursing Home
- What is being tested?
- immersive virtual reality and classic reminiscence workshops
- Type of treatment
- Medical device
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteFrance
- Study dates
- 10 Oct 2025to Mar 2027
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- Residents of the long-term care facilities of the Amiens-Picardie University Hospital,
- Residents with mild to moderate Alzheimer's disease or related diseases, i.e. with an MMSE ≥ 10,
- Residents or their legal representative agreeing to participate in the study.
Who cannot join
- Non-residents of the long-term care facilities of the Amiens-Picardie University Hospital,
- Residents with an MMS < 10,
- Residents or their legal representative refusing to participate in the study,
- Residents in terminal palliative care,
- Residents with disruptive behavioral disorders.
Trial locations and contacts
1 site in 1 country.
About this study
This project provides the easiest possible access to heritage elements that older persons with Alzheimer's disease or related diseases knew well but to which they no longer have access due to the motor and functional dependencies they present. It will strengthen the possibilities of reminiscence by using, rather than the usual supports, virtual reality technology to reinforce the immersion effect. It will involve carrying out virtual reality reminiscence workshops intended for residents in nursing home with Alzheimer's disease or related diseases and allowing them to explore the heritage of towns and villages in the Somme region thanks to these innovative solutions. The aim of this project is to reduce behavioral disorders and improve their quality of life.
- Conditions
- Virtual Reality, Reminiscence Therapy, Nursing Home, Alzheimer's Disease or Related Diseases, Crossover Study
- Being tested
- immersive virtual reality, classic reminiscence workshops
- Keywords
- Virtual reality, Reminiscence therapy, Nursing home, Alzheimer's disease or related diseases, crossover study
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
immersive virtual realityDevice
The research procedure will be the realization of reminiscence workshops in immersive virtual reality. The residents will be equipped with a virtual reality headset where they will enjoy 360° panoramas that will immerse them in the heart of villages in the Amiens basin and in particular their village based on 3 to 5 images per village: church square, village square, town hall, emblematic places, etc.
classic reminiscence workshopsDevice
It will be compared to classic reminiscence workshops in which the organizer will propose to discuss memories and past experiences using photographs, objects or music in the control arm.
| Study group | Role | What they receive |
|---|---|---|
| immersive virtual reality | Experimental | The residents will be equipped with a virtual reality headset where they will enjoy 360° panoramas that will immerse them in the heart of villages in the Amiens basin and in particular their village based on 3 to 5 images per village: church square, village square, town hall, emblematic places, etc Receives: Device: immersive virtual reality |
| classic reminiscence workshops | Active comparator | classic reminiscence workshops in which the organizer will propose to discuss memories and past experiences using photographs, objects or music in the control arm Receives: Device: classic reminiscence workshops |
What is being measured
The primary outcome is the main question the study is designed to answer.
Reduced behavioral problem frequency in immersive virtual reality group
Efficacy in reducing behavioral problems will be assessed using the sum of scores on the NPI-ES anxiety, depression, and apathy subscales.
Measured: 1 year
Secondary outcomes (1)
Improved quality of life in the immersive virtual reality group
improving the quality of life will be assessed using a quality of life scale developed for patients with Alzheimer's disease or related diseases, the QOL-AD scale validated in French.
The QOL-AD is administered in interview format to individuals with dementia, following the instructions below.
Scoring instructions for QOL-AD:
Points are assigned to each item as follows: poor = 1, fair = 2, good = 3, excellent = 4.
The total score is the sum of all 13 items.
Measured: 1 year
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted7 May 2025
- Study start10 Oct 2025
- Primary completionNov 2026 (estimated)
- Study completionMar 2027 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Virtual RealityStudies of the same condition, open and under way.
- More trials run by Centre Hospitalier Universitaire, AmiensThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Centre Hospitalier Universitaire, Amiens
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06960915
- Sponsor's protocol ID
- PI2025_843_0068
- Acronym
- ReminiSOMME
- Status last verified
- Feb 2026
- First submitted
- 29 Apr 2025
- Last updated
- 11 Feb 2026
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Study at a glance
From the registry record, last updated by the sponsor on 11 Feb 2026. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Efficacy of Virtual Reality Reminiscence Therapy in Nursing Home Residents With Alzheimer's Disease or Related Diseases
- ClinicalTrials.gov ID
- NCT06960915
- Acronym / sponsor ID
- ReminiSOMME / PI2025_843_0068
- Conditions
- Virtual Reality, Reminiscence Therapy, Nursing Home, Alzheimer's Disease or Related Diseases, Crossover Study
- Keywords
- Virtual reality, Reminiscence therapy, Nursing home, Alzheimer's disease or related diseases, crossover study
- Study type
- Interventional
- Recruitment status
- Active, not recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Centre Hospitalier Universitaire, AmiensUniversity, hospital or other
- Study start
- 10 Oct 2025 (actual)
- Primary completion
- Nov 2026 (estimated)
- Study completion
- Mar 2027 (estimated)
- First posted
- 7 May 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This project provides the easiest possible access to heritage elements that older persons with Alzheimer's disease or related diseases knew well but to which they no longer have access due to the motor and functional dependencies they present. It will strengthen the possibilities of reminiscence by using, rather than the usual supports, virtual reality technology to reinforce the immersion effect. It will involve carrying out virtual reality reminiscence workshops intended for residents in nursing home with Alzheimer's disease or related diseases and allowing them to explore the heritage of towns and villages in the Somme region thanks to these innovative solutions. The aim of this project is to reduce behavioral disorders and improve their quality of life.
Study design
- Primary purpose
- Other
- Allocation
- Randomised
- Intervention model
- Crossover
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| immersive virtual reality | Experimental | Device: immersive virtual realityThe residents will be equipped with a virtual reality headset where they will enjoy 360° panoramas that will immerse them in the heart of villages in the Amiens basin and in particular their village based on 3 to 5 images per village: church square, village square, town hall, emblematic places, etc |
| classic reminiscence workshops | Active comparator | Device: classic reminiscence workshopsclassic reminiscence workshops in which the organizer will propose to discuss memories and past experiences using photographs, objects or music in the control arm |
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- Residents of the long-term care facilities of the Amiens-Picardie University Hospital,
- Residents with mild to moderate Alzheimer's disease or related diseases, i.e. with an MMSE ≥ 10,
- Residents or their legal representative agreeing to participate in the study.
Key exclusion criteria (5 listed)
- Non-residents of the long-term care facilities of the Amiens-Picardie University Hospital,
- Residents with an MMS < 10,
- Residents or their legal representative refusing to participate in the study,
- Residents in terminal palliative care,
- Residents with disruptive behavioral disorders.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| immersive virtual realityThe research procedure will be the realization of reminiscence workshops in immersive virtual reality. The residents will be equipped with a virtual reality headset where they will enjoy 360° panoramas that will immerse them in the heart of villages in the Amiens basin and in particular their village based on 3 to 5 images per village: church square, village square, town hall, emblematic places, etc. | Device | immersive virtual reality |
| classic reminiscence workshopsIt will be compared to classic reminiscence workshops in which the organizer will propose to discuss memories and past experiences using photographs, objects or music in the control arm. | Device | classic reminiscence workshops |
Primary outcome
Reduced behavioral problem frequency in immersive virtual reality group
Time frame: 1 year
Efficacy in reducing behavioral problems will be assessed using the sum of scores on the NPI-ES anxiety, depression, and apathy subscales.
1 secondary outcome
Improved quality of life in the immersive virtual reality group
Time frame: 1 year
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 11 Feb 2026.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing immersive virtual reality and classic reminiscence workshops in people with Virtual Reality and Reminiscence Therapy, run by Centre Hospitalier Universitaire, Amiens at 1 site in France.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 5 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 11 Feb 2026. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in France. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Reduced behavioral problem frequency in immersive virtual reality group (time frame: 1 year). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 11 Feb 2026.