Age-related Strength LossNCT06976060
High-Intensity Interval Training in a Community Gym
A study testing High-Intensity Interval Training in people with Age-related Strength Loss, run by Creighton University at 1 site in United States.
Trial summary
This study will deliver a 9 week high intensity interval training (HIIT) class using functional movements within a community based gym. The class will be twice a week. Outcomes are focused on cardiovascular endurance, balance, strength and muscle size and muscle quality changes. The outcomes will be assessed weekly. Read more about this study
- Who is it for?
- Ages 50 to 95 yearsHealthy volunteers can take part
- Conditions the study is for
- Age-related Strength Loss
- What is being tested?
- High-Intensity Interval Training
- Type of treatment
- Lifestyle or therapy programme
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 6 participants
- Where
- 1 siteUnited States
- Study dates
- 3 Jun 2025to 7 Aug 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 50 to 95 years
- All sexes
- Healthy volunteers accepted
- Adult, Older adult
Who may be able to join
- no contraindications to exercise (PAR-Q+)
- do not have severe mental impairment (>14 on the SAGE)
- ability to walk 100 ft without the use of an assistive device
Who cannot join
None listed.
Trial locations and contacts
1 site in 1 country.
United States1 site
UNMC Engage Wellness Medical Fitness Center
Omaha, Nebraska, 68105
About this study
This study will deliver a 9 week high intensity interval training (HIIT) class using functional movements within a community based gym. The class will be twice a week. Outcomes are focused on cardiovascular endurance, balance, strength and muscle size and muscle quality changes. The outcomes will be assessed weekly.
Read the detailed description
We will measure cardiovascular endurance (2-minute Step Test; 2MST), balance (Functional Gait Assessment; FGA), muscular strength (Grip Strength and 5 times sit-to-stand; 5xSTS) and muscle size (thickness) and quality (echo intensity) on a weekly basis over the 9 week HIIT class.
- Conditions
- Age-related Strength Loss
- Being tested
- High-Intensity Interval Training
- Keywords
- high-intensity interval training, older adults
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
High-Intensity Interval TrainingBehavioural
High-intensity interval training (HIIT) sessions will occur twice per week, on non-consecutive days. Each training session will last 45-60 minutes and consist of eight functional movement exercises incorporating the entire body (upper body, lower body, core/stability, cycling, and agility). Participants will complete two rounds of the 8-exercise circuit with 2-minutes of rest between rounds. The load/resistance used for each exercise will be self-selected by the participants that equates to 15-18 on the RPE scale. During each round, participants will have 1 minute to complete as many repetitions as possible of a given exercise and then have 1 minute of rest before completing the next exercise - giving the participants a 1:1 exercise-to-rest ratio.
| Study group | Role | What they receive |
|---|---|---|
| High-Intensity Interval Training | Experimental | Not described Receives: Behavioral: High-Intensity Interval Training |
What is being measured
The primary outcome is the main question the study is designed to answer.
2-minute Step Test Performance
Cardiovascular endurance metric, number of repetitions a single leg is able to complete in 2 minutes.
Measured: Baseline and weekly over the 9 week intervention
Secondary outcomes (5)
Functional Gait Asssessment
Balance metric, reporting the score out of 30 points
Measured: Baseline and weekly over the 9 week intervention
5 times sit to stand
Lower extremity muscular strength. Recording the amount of time to complete 5 sit to stand repetitions.
Measured: Baseline and weekly over the 9 week intervention
Grip Strength
Upper Extremity Strength assessment. Peak grip strength measured with hand held dynamometer.
Measured: Baseline and weekly over the 9 week intervention
Muscle Thickness
Muscle thickness will be recorded via ultrasound
Measured: Baseline and weekly over the 9 week intervention
Muscle Echo Intensity
Ultrasound images of the vastus lateralis will be obtained and echo intensity for the muscle will be assessed.
Measured: Baseline and weekly over the 9 week intervention
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted16 May 2025
- Study start3 Jun 2025
- Primary completion7 Aug 2025
- Study completion7 Aug 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Age-related Strength LossStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Enrolment
- 6 participants (actual)
Sponsor and investigators
- Lead sponsor
- Creighton University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06976060
- Sponsor's protocol ID
- 2005507
- Status last verified
- May 2025
- First submitted
- 9 May 2025
- Last updated
- 22 Sep 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 22 Sep 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- High-Intensity Interval Training in a Community Gym
- ClinicalTrials.gov ID
- NCT06976060
- Acronym / sponsor ID
- 2005507
- Conditions
- Age-related Strength Loss
- Keywords
- high-intensity interval training, older adults
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 6 participants (actual)
- Lead sponsor
- Creighton UniversityUniversity, hospital or other
- Study start
- 3 Jun 2025 (actual)
- Primary completion
- 7 Aug 2025 (actual)
- Study completion
- 7 Aug 2025 (actual)
- First posted
- 16 May 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study will deliver a 9 week high intensity interval training (HIIT) class using functional movements within a community based gym. The class will be twice a week. Outcomes are focused on cardiovascular endurance, balance, strength and muscle size and muscle quality changes. The outcomes will be assessed weekly.
Detailed description
We will measure cardiovascular endurance (2-minute Step Test; 2MST), balance (Functional Gait Assessment; FGA), muscular strength (Grip Strength and 5 times sit-to-stand; 5xSTS) and muscle size (thickness) and quality (echo intensity) on a weekly basis over the 9 week HIIT class.
Study design
- Primary purpose
- Prevention
- Allocation
- Not applicable
- Intervention model
- Single group
- Masking
- None (open label)
- Number of arms
- 1
| Arm | Type | Receives |
|---|---|---|
| High-Intensity Interval Training | Experimental | Behavioral: High-Intensity Interval Training |
Who may qualify
- Ages
- 50 to 95 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- no contraindications to exercise (PAR-Q+)
- do not have severe mental impairment (>14 on the SAGE)
- ability to walk 100 ft without the use of an assistive device
Key exclusion criteria (0 listed)
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| High-Intensity Interval TrainingHigh-intensity interval training (HIIT) sessions will occur twice per week, on non-consecutive days. Each training session will last 45-60 minutes and consist of eight functional movement exercises incorporating the entire body (upper body, lower body, core/stability, cycling, and agility). Participants will complete two rounds of the 8-exercise circuit with 2-minutes of rest between rounds. The load/resistance used for each exercise will be self-selected by the participants that equates to 15-18 on the RPE scale. During each round, participants will have 1 minute to complete as many repetitions as possible of a given exercise and then have 1 minute of rest before completing the next exercise - giving the participants a 1:1 exercise-to-rest ratio. | Behavioural | High-Intensity Interval Training |
Primary outcome
2-minute Step Test Performance
Time frame: Baseline and weekly over the 9 week intervention
Cardiovascular endurance metric, number of repetitions a single leg is able to complete in 2 minutes.
5 secondary outcomes
Functional Gait Asssessment
Time frame: Baseline and weekly over the 9 week intervention
5 times sit to stand
Time frame: Baseline and weekly over the 9 week intervention
Grip Strength
Time frame: Baseline and weekly over the 9 week intervention
Muscle Thickness
Time frame: Baseline and weekly over the 9 week intervention
Muscle Echo Intensity
Time frame: Baseline and weekly over the 9 week intervention
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 Sep 2025.
Related trials for Age-related Strength Loss
Not yet recruiting
Muscle Aging Evaluation
Preventing Age-Related Muscle Loss: the Role of Exercise in Improving Strength, Function, and Well-being
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing High-Intensity Interval Training in people with Age-related Strength Loss, run by Creighton University at 1 site in United States.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 0 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 22 Sep 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in United States. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
2-minute Step Test Performance (time frame: Baseline and weekly over the 9 week intervention). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 Sep 2025; AzTrials last refreshed its copy on 2 Nov 2026.