Postoperative PainNCT06978179
Ultrasound-Guided QL Block Versus TAP Block For Post-Operative Pain In Lower Abdominal Surgeries
A study testing Ultrasound-Guided Quadratus Lumborum Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients and Ultrasound-Guided Transversus Abdominis Plane Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients in people with Postoperative Pain, run by Sohag University at 1 site in Egypt.
Trial summary
This study aims to compare the efficacy of ultrasound-guided QL block and TAP block for postoperative pain management following lower abdominal surgeries. Read more about this study
- Who is it for?
- Ages 18 to 65 years
- Conditions the study is for
- Postoperative Pain
- What is being tested?
- Ultrasound-Guided Quadratus Lumborum Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients and Ultrasound-Guided Transversus Abdominis Plane Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients
- Type of treatment
- Surgery or procedure
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 50 participants
- Where
- 1 siteEgypt
- Study dates
- 14 Apr 2025to 15 Oct 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 65 years
- All sexes
- No healthy volunteers
- Adult, Older adult
Who may be able to join
- patients aged from 18 to 65 years old.
- American Society of Anesthesiologists (ASA) physical status I - II.
- Patients scheduled for elective lower abdominal surgery.
Who cannot join
- Patient refusal.
- Patients with BMI (body mass index) > 35 kg.m-2 , [morbid obesity].
- Patients with significant neurological, psychatric or neuromascular disease.
- Patients had local skin infection at the block injection site.
- Patients who operated under epidural and patient-controlled analgesia [PCA].
- Sensitivity to prescribed analgesia.
- Coagulopathies or those who had uncontrolled chronic medical disease [e.g. diabetes mellitus, hypertension, or cardiac diseases].
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Wesam A Abo El-Wafa, Professor contact
Egypt1 site, 1 recruiting
- Recruiting
Sohag University Hospital
Sohag
Magdy M Amin, Professor, 01090801900
About this study
Official title: Ultrasound-Guided Quadratus Lumborum Block Versus Transversus Abdominis Plane Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients, Prospective, Comparative Randomized Study
This study aims to compare the efficacy of ultrasound-guided QL block and TAP block for postoperative pain management following lower abdominal surgeries.
- Conditions
- Postoperative Pain
- Being tested
- Ultrasound-Guided Quadratus Lumborum Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients, Ultrasound-Guided Transversus Abdominis Plane Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients
- Medical subject headings
- Pain, Postoperative
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Ultrasound-Guided Quadratus Lumborum Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult PatientsProcedure or surgery
Group ( 1 ) QLB "Type III": Patients will receive QLB performedwith20ml of diluted bupivacaine 0.25% on each side.
Ultrasound-Guided Transversus Abdominis Plane Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult PatientsProcedure or surgery
Group ( 2 ) TAP: Patients will receive TAP block performed with 20ml of diluted bupivacaine 0.25% on each side.
| Study group | Role | What they receive |
|---|---|---|
| US Guided QL Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients | Active comparator | Group ( 1 ) QLB "Type III": Patients will receive QLB performedwith20ml of diluted bupivacaine 0.25% on each side. Receives: Procedure: Ultrasound-Guided Quadratus Lumborum Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients |
| US Guided TAP Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients | Active comparator | Group ( 2 ) TAP: Patients will receive TAP block performed with 20ml of diluted bupivacaine 0.25% on each side. Receives: Procedure: Ultrasound-Guided Transversus Abdominis Plane Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients |
What is being measured
The primary outcome is the main question the study is designed to answer.
efficacy of ultrasound-guided QL block and TAP block for postoperative pain management following lower abdominal surgeries.
Visual Analog Scale (VAS) at rest and at movement
Measured: 48 hours after operation
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted18 May 2025
- Study start14 Apr 2025
- Primary completion15 Oct 2025 (estimated)
- Study completion15 Oct 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (3)Papers the sponsor has linked to this study.
- Other trials for Postoperative PainStudies of the same condition, open and under way.
- More trials run by Sohag UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Enrolment
- 50 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Sohag University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Ahmed Mohamed Aboelnaga, Sohag University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06978179
- Sponsor's protocol ID
- Soh-Med--25-4-01MS
- Status last verified
- Apr 2025
- First submitted
- 10 May 2025
- Last updated
- 18 May 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Publications
Borglum J, Gogenur I, Bendtsen TF. Abdominal wall blocks in adults. Curr Opin Anaesthesiol. 2016 Oct;29(5):638-43. doi: 10.1097/ACO.0000000000000378.
PubMed 27429253Wick EC, Grant MC, Wu CL. Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review. JAMA Surg. 2017 Jul 1;152(7):691-697. doi: 10.1001/jamasurg.2017.0898.
PubMed 28564673Chen Q, Beal EW, Okunrintemi V, Cerier E, Paredes A, Sun S, Olsen G, Pawlik TM. The Association Between Patient Satisfaction and Patient-Reported Health Outcomes. J Patient Exp. 2019 Sep;6(3):201-209. doi: 10.1177/2374373518795414. Epub 2018 Aug 27.
PubMed 31535008
Study at a glance
From the registry record, last updated by the sponsor on 18 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Ultrasound-Guided Quadratus Lumborum Block Versus Transversus Abdominis Plane Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients, Prospective, Comparative Randomized Study
- ClinicalTrials.gov ID
- NCT06978179
- Acronym / sponsor ID
- Soh-Med--25-4-01MS
- Conditions
- Postoperative Pain
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 50 participants (estimated)
- Lead sponsor
- Sohag UniversityUniversity, hospital or other
- Study start
- 14 Apr 2025 (actual)
- Primary completion
- 15 Oct 2025 (estimated)
- Study completion
- 15 Oct 2025 (estimated)
- First posted
- 18 May 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
This study aims to compare the efficacy of ultrasound-guided QL block and TAP block for postoperative pain management following lower abdominal surgeries.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- None (open label)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| US Guided QL Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients | Active comparator | Procedure: Ultrasound-Guided Quadratus Lumborum Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult PatientsGroup ( 1 ) QLB "Type III": Patients will receive QLB performedwith20ml of diluted bupivacaine 0.25% on each side. |
| US Guided TAP Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients | Active comparator | Procedure: Ultrasound-Guided Transversus Abdominis Plane Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult PatientsGroup ( 2 ) TAP: Patients will receive TAP block performed with 20ml of diluted bupivacaine 0.25% on each side. |
Who may qualify
- Ages
- 18 to 65 years
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
Key inclusion criteria (3 listed)
- patients aged from 18 to 65 years old.
- American Society of Anesthesiologists (ASA) physical status I - II.
- Patients scheduled for elective lower abdominal surgery.
Key exclusion criteria (7 listed)
- Patient refusal.
- Patients with BMI (body mass index) > 35 kg.m-2 , [morbid obesity].
- Patients with significant neurological, psychatric or neuromascular disease.
- Patients had local skin infection at the block injection site.
- Patients who operated under epidural and patient-controlled analgesia [PCA].
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Ultrasound-Guided Quadratus Lumborum Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult PatientsGroup ( 1 ) QLB "Type III": Patients will receive QLB performedwith20ml of diluted bupivacaine 0.25% on each side. | Procedure or surgery | US Guided QL Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients |
| Ultrasound-Guided Transversus Abdominis Plane Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult PatientsGroup ( 2 ) TAP: Patients will receive TAP block performed with 20ml of diluted bupivacaine 0.25% on each side. | Procedure or surgery | US Guided TAP Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients |
Primary outcome
efficacy of ultrasound-guided QL block and TAP block for postoperative pain management following lower abdominal surgeries.
Time frame: 48 hours after operation
Visual Analog Scale (VAS) at rest and at movement
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 18 May 2025.
- Background: PubMed 27429253Borglum J, Gogenur I, Bendtsen TF. Abdominal wall blocks in adults. Curr Opin Anaesthesiol. 2016 Oct;29(5):638-43. doi: 10.1097/ACO.0000000000000378.
- Background: PubMed 28564673Wick EC, Grant MC, Wu CL. Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review. JAMA Surg. 2017 Jul 1;152(7):691-697. doi: 10.1001/jamasurg.2017.0898.
- Background: PubMed 31535008Chen Q, Beal EW, Okunrintemi V, Cerier E, Paredes A, Sun S, Olsen G, Pawlik TM. The Association Between Patient Satisfaction and Patient-Reported Health Outcomes. J Patient Exp. 2019 Sep;6(3):201-209. doi: 10.1177/2374373518795414. Epub 2018 Aug 27.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Wesam A Abo El-Wafa, Professor contact
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Ultrasound-Guided Quadratus Lumborum Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients and Ultrasound-Guided Transversus Abdominis Plane Block For Post-Operative Pain In Lower Abdominal Surgeries In Adult Patients in people with Postoperative Pain, run by Sohag University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 7 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 18 May 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Ahmed M Abo El-Naga, Resident (01018434601, ahmed_abuelnaga_post@med.sohag.edu.eg), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
efficacy of ultrasound-guided QL block and TAP block for postoperative pain management following lower abdominal surgeries. (time frame: 48 hours after operation). It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06978179, which also lists 3 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 18 May 2025.