ChondromalaciafemalesNCT06980883
Assessing Impact of Myofascial Release Versus Dry Needling for Chondromalacia in Adult Females
A study testing Dry Needling, myofascial release and (traditional exercises) in people with Chondromalacia, run by Badr University at 1 site in Egypt.
Trial summary
Assessing Impact of Myofascial Release versus Dry Needling for Chondromalacia in Adult females. The study employed a Randomized Controlled Trial (RCT) design. Read more about this study
- Who is it for?
- Ages 18 to 50 years, women only
- Conditions the study is for
- Chondromalacia
- What is being tested?
- Dry Needling, myofascial release and (traditional exercises)
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 45 participants
- Where
- 1 siteEgypt
- Study dates
- 1 Sep 2023to 15 May 2025
- Phase
- Interventional
- Are there results?
- None posted in the registry
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 to 50 years
- Women only
- No healthy volunteers
- Adult
Who may be able to join
- Age between 18-50 years old, the anterior knee pain recorded while one of the following activities at least :ascending and descending stairs, prolonged sitting and kneeling.
- Subject experiences pain during palpation of patellar facets or while performing a 25-cm step down test or double legged squat. (Iiona, 2020)
Who cannot join
- excluded meniscal or intra-articular pathological conditions, cruciate or collateral ligaments involvement, tenderness over the patellar tendon .
- These participants were randomly assigned to one of three groups, each consisting of 15 patients all received treatment for 3 weaks, 2 sessions per weak.
Trial locations and contacts
1 site in 1 country.
About this study
Official title: Assessing Impact of Myofascial Release Versus Dry Needling for Chondromalacia in Adult Females: A Randomized Controlled Trial
Assessing Impact of Myofascial Release versus Dry Needling for Chondromalacia in Adult females. The study employed a Randomized Controlled Trial (RCT) design.
Read the detailed description
A total of 45 female patients diagnosed with chondromalacia and confirmed by physical examination using a patellar grind test to confirm Clarke's sign were recruited for this study from the out patient clinic and Soad Kafafi's educational hospital , Investigations that analyzed the H/Q ratio by the use of gravity corrected isokinetic strength testing.
Inclusion criteria were:
- Age between 18-50 years old, the anterior knee pain recorded while one of the following activities at least :ascending and descending stairs, prolonged sitting and kneeling.
- Subject experiences pain during palpation of patellar facets or while performing a 25-cm step down test or double legged squat.
- Exclusion criteria included meniscal or intra-articular pathological conditions, cruciate or collateral ligaments involvement, tenderness over the patellar tendon .
- These participants were randomly assigned to one of three groups, each consisting of 15 patients all received treatment for 3 weeks, 2 sessions per weak.
Group 1: Received dry needling combined with traditional treatment( straight leg raising and isometric quadriceps exercises) for 3 weeks, 2 sessions per weak.
Group 2: Received myofascial release in addition to traditional treatment for 3 weeks, 2 sessions per week. Evaluation of fascial restriction was assessed using the therapists elbow.
Myofascial chain release:
Position of the patient: Supine lying, prone lying and side lying Position of the therapist: Side of the patient limb to be treated
-Technique: Using the therapist elbow a vertical release proximal to the attachment of the muscle belly or fascia was applied. Once an end-feel was reached a slow stroke down the length of the target tissue was performed along with monitoring the indirect feedback and tissue tension to identify any additional restrictions. The long stroke was repeated in a line parallel to the first stroke. It was continued until an end-feel is reached throughout the entire muscle belly or fascia on the most restricted/ painful points.
Traditional Treatment ( exercise) : Applied uniformly across all groups, comprising straight leg raising and isometric quadriceps exercises (2 days per week).
Group 3: Received only the traditional treatment only for 3 weeks, 2 sessions per weak.
- Conditions
- Chondromalacia
- Being tested
- Dry Needling, myofascial release, (traditional exercises)
- Keywords
- chondromalacia,females, myofascial release, and dry needles
- Medical subject headings
- Cartilage Diseases
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Dry NeedlingOther
dry needles Administered to patients in Group 1 as part of their treatment regimen( 2 days per week).
myofascial releaseOther
Myofascial Release: Provided to patients in Group 2 along with traditional treatment( 2 days per week).
Evaluation of fascial restriction was assessed using the therapists elbow. Any restrictions felt were assessed and given treatment.Myofascial chain release- Position of the patient- Supine lying, prone lying and side lying Position of the therapist- Side of the patient limb to be treated
- Technique-Using the therapist elbow a vertical release proximal to the attachment of the muscle belly or fascia was applied. Once an end-feel was reached a slow stroke down the length of the target tissue was performed along with monitoring the indirect feedback and tissue tension to identify any additional restrictions. The long stroke was repeated in a line parallel to the first stroke. It was continued until an end-feel is reached throughout the entire muscle belly or fascia on the most restricted/ painful points.
(traditional exercises)Other
comprising straight leg raising and isometric quadriceps exercises (2 days per week).
| Study group | Role | What they receive |
|---|---|---|
| group 1:adding dry needle to traditional exercises | Experimental | Received dry needling combined with traditional treatment( straight leg raising and isometric quadriceps exercises) for 3 weeks, 2 sessions per weak. Receives: Other: Dry Needling; Other: (traditional exercises) |
| group 2: adding myofascial release to traditional exercises | Experimental | Myofascial Release: Provided to patients in Group 2 along with traditional treatment( 2 days per week).Evaluation of fascial restriction was assessed using the therapists elbow. Any restrictions felt were assessed and given treatment. Receives: Other: myofascial release; Other: (traditional exercises) |
| group 3: (control group): Applied Traditional exercise | Active comparator | Traditional Treatment ( exercise) : Applied uniformly across all groups, comprising straight leg raising and isometric quadriceps exercises (2 days per week). Receives: Other: (traditional exercises) |
What is being measured
The primary outcome is the main question the study is designed to answer.
The isokinetic muscle strength
- Peak Torque (PT): Measured using the isokinetic dynamometer system to assess the strength of the muscles.
- AGO/ANT Ratio: Evaluated using the isokinetic dynamometer system to examine the balance between agonist and antagonist muscle groups.
Measured: 3 weeks
pain intensity by visual analogue scale.
Visual Analogue Scale (VAS): Utilized to measure the intensity of pain experienced by the patients.
Measured: 3 Weeks
Secondary outcomes (2)
Quality of Life physical and mental states
Quality of Life Scale Questionnaire (QLS): Administered to assess both the physical and mental status of the patients.
Measured: 3 Weeks
Activity and functional levels of Lower Extremity
Lower Extremity Scale Questionnaire (LES): Used to evaluate the activity levels and functionality of the patients' lower extremities.
Measured: 3 weeks
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted20 May 2025
- Study start1 Sep 2023
- Primary completion1 May 2025
- Study completion15 May 2025
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for ChondromalaciaStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Model description
- A total of 45 adult female diagnosed with chondromalacia and confirmed by physical examination using a patellar grind test to confirm clarke's sign were recruited for this study from the out patient clinic and soad kafafi's educational hospital , Investigations that analysed the H/Q ratio by the use of gravity corrected isokinetic strength testing
- Masking
- Double blind
- Who is masked
- Investigator, Outcomes assessor
- Enrolment
- 45 participants (actual)
Sponsor and investigators
- Lead sponsor
- Badr University
- Sponsor type
- University, hospital or other
- Responsible party
- Principal investigator, Doaa Saeed Mohamed, Badr University
- Investigators
- Doaa S Mohamed, lecturer, Principal investigator, lecturer physical therapy for women health Badr University at Cairo
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06980883
- Sponsor's protocol ID
- IRB00014233-6
- Acronym
- females
- Status last verified
- May 2025
- First submitted
- 28 Apr 2025
- Last updated
- 20 May 2025
- Results posted
- No
- Data monitoring committee
- Yes
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 20 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Assessing Impact of Myofascial Release Versus Dry Needling for Chondromalacia in Adult Females: A Randomized Controlled Trial
- ClinicalTrials.gov ID
- NCT06980883
- Acronym / sponsor ID
- females / IRB00014233-6
- Conditions
- Chondromalacia
- Keywords
- chondromalacia,females, myofascial release, and dry needles
- Study type
- Interventional
- Recruitment status
- Completed
- Enrolment
- 45 participants (actual)
- Lead sponsor
- Badr UniversityUniversity, hospital or other
- Study start
- 1 Sep 2023 (actual)
- Primary completion
- 1 May 2025 (actual)
- Study completion
- 15 May 2025 (actual)
- First posted
- 20 May 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Assessing Impact of Myofascial Release versus Dry Needling for Chondromalacia in Adult females. The study employed a Randomized Controlled Trial (RCT) design.
Detailed description
A total of 45 female patients diagnosed with chondromalacia and confirmed by physical examination using a patellar grind test to confirm Clarke's sign were recruited for this study from the out patient clinic and Soad Kafafi's educational hospital , Investigations that analyzed the H/Q ratio by the use of gravity corrected isokinetic strength testing.
Inclusion criteria were:
- Age between 18-50 years old, the anterior knee pain recorded while one of the following activities at least :ascending and descending stairs, prolonged sitting and kneeling.
- Subject experiences pain during palpation of patellar facets or while performing a 25-cm step down test or double legged squat.
- Exclusion criteria included meniscal or intra-articular pathological conditions, cruciate or collateral ligaments involvement, tenderness over the patellar tendon .
- These participants were randomly assigned to one of three groups, each consisting of 15 patients all received treatment for 3 weeks, 2 sessions per weak.
Group 1: Received dry needling combined with traditional treatment( straight leg raising and isometric quadriceps exercises) for 3 weeks, 2 sessions per weak.
Group 2: Received myofascial release in addition to traditional treatment for 3 weeks, 2 sessions per week. Evaluation of fascial restriction was assessed using the therapists elbow.
Myofascial chain release:
Position of the patient: Supine lying, prone lying and side lying Position of the therapist: Side of the patient limb to be treated
-Technique: Using the therapist elbow a vertical release proximal to the attachment of the muscle belly or fascia was applied. Once an end-feel was reached a slow stroke down the length of the target tissue was performed along with monitoring the indirect feedback and tissue tension to identify any additional restrictions. The long stroke was repeated in a line parallel to the first stroke. It was continued until an end-feel is reached throughout the entire muscle belly or fascia on the most restricted/ painful points.
Traditional Treatment ( exercise) : Applied uniformly across all groups, comprising straight leg raising and isometric quadriceps exercises (2 days per week).
Group 3: Received only the traditional treatment only for 3 weeks, 2 sessions per weak.
Study design
- Primary purpose
- Health services research
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Double blind (investigator, outcomes assessor)
- Number of arms
- 3
- Model description
- A total of 45 adult female diagnosed with chondromalacia and confirmed by physical examination using a patellar grind test to confirm clarke's sign were recruited for this study from the out patient clinic and soad kafafi's educational hospital , Investigations that analysed the H/Q ratio by the use of gravity corrected isokinetic strength testing
| Arm | Type | Receives |
|---|---|---|
| group 1:adding dry needle to traditional exercises | Experimental | Other: Dry Needling, Other: (traditional exercises)Received dry needling combined with traditional treatment( straight leg raising and isometric quadriceps exercises) for 3 weeks, 2 sessions per weak. |
| group 2: adding myofascial release to traditional exercises | Experimental | Other: myofascial release, Other: (traditional exercises)Myofascial Release: Provided to patients in Group 2 along with traditional treatment( 2 days per week).Evaluation of fascial restriction was assessed using the therapists elbow. Any restrictions felt were assessed and given treatment. |
| group 3: (control group): Applied Traditional exercise | Active comparator | Other: (traditional exercises)Traditional Treatment ( exercise) : Applied uniformly across all groups, comprising straight leg raising and isometric quadriceps exercises (2 days per week). |
Who may qualify
- Ages
- 18 to 50 years
- Sex
- Female only
- Healthy volunteers
- Not accepted
- Age groups
- Adult
Key inclusion criteria (2 listed)
- Age between 18-50 years old, the anterior knee pain recorded while one of the following activities at least :ascending and descending stairs, prolonged sitting and kneeling.
- Subject experiences pain during palpation of patellar facets or while performing a 25-cm step down test or double legged squat. (Iiona, 2020)
Key exclusion criteria (2 listed)
- excluded meniscal or intra-articular pathological conditions, cruciate or collateral ligaments involvement, tenderness over the patellar tendon .
- These participants were randomly assigned to one of three groups, each consisting of 15 patients all received treatment for 3 weaks, 2 sessions per weak.
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Dry Needlingdry needles Administered to patients in Group 1 as part of their treatment regimen( 2 days per week). | Other | group 1:adding dry needle to traditional exercises |
| myofascial releaseMyofascial Release: Provided to patients in Group 2 along with traditional treatment( 2 days per week). Evaluation of fascial restriction was assessed using the therapists elbow. Any restrictions felt were assessed and given treatment.Myofascial chain release- Position of the patient- Supine lying, prone lying and side lying Position of the therapist- Side of the patient limb to be treated - Technique-Using the therapist elbow a vertical release proximal to the attachment of the muscle belly or fascia was applied. Once an end-feel was reached a slow stroke down the length of the target tissue was performed along with monitoring the indirect feedback and tissue tension to identify any additional restrictions. The long stroke was repeated in a line parallel to the first stroke. It was continued until an end-feel is reached throughout the entire muscle belly or fascia on the most restricted/ painful points. | Other | group 2: adding myofascial release to traditional exercises |
| (traditional exercises)comprising straight leg raising and isometric quadriceps exercises (2 days per week). | Other | group 1:adding dry needle to traditional exercises, group 2: adding myofascial release to traditional exercises, group 3: (control group): Applied Traditional exercise |
Primary outcome
The isokinetic muscle strength
Time frame: 3 weeks
* Peak Torque (PT): Measured using the isokinetic dynamometer system to assess the strength of the muscles. * AGO/ANT Ratio: Evaluated using the isokinetic dynamometer system to examine the balance between agonist and antagonist muscle groups.
pain intensity by visual analogue scale.
Time frame: 3 Weeks
Visual Analogue Scale (VAS): Utilized to measure the intensity of pain experienced by the patients.
2 secondary outcomes
Quality of Life physical and mental states
Time frame: 3 Weeks
Activity and functional levels of Lower Extremity
Time frame: 3 weeks
Results and safety
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 20 May 2025.
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
Doaa S Mohamed, lecturer principal investigator
lecturer physical therapy for women health Badr University at Cairo
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Dry Needling, myofascial release and (traditional exercises) in people with Chondromalacia, run by Badr University at 1 site in Egypt.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 2 inclusion and 2 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: finished, as of the sponsor's last update on 20 May 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Egypt. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
The study is completed, but results are not available in the source record. That does not mean the treatment did or did not work.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
The isokinetic muscle strength (time frame: 3 weeks). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 20 May 2025.