Adhesive CapsulitisNCT06985836
Effect of Mulligan Mobilization With or Without Niel Asher Technique in Patients With Adhesive Capsulitis
A study testing Mulligan Mobilization and Niel Asher technique and Mulligan Mobilization and Conventional physiotherapy. in people with Adhesive Capsulitis, run by Riphah International University at 1 site in Pakistan.
Trial summary
Adhesive capsulitis is a prevalent condition characterized by pain and stiffness in shoulder joint and surrounding muscles shows decrease range and strength in patients with adhesive capsulitis. Read more about this study
- Who is it for?
- Ages 40 to 60 yearsHealthy volunteers can take part
- Conditions the study is for
- Adhesive Capsulitis
- What is being tested?
- Mulligan Mobilization and Niel Asher technique and Mulligan Mobilization and Conventional physiotherapy.
- Could I receive a placebo?
- No, everyone receives an active treatment
- How many people
- 42 participants
- Where
- 1 sitePakistan
- Study dates
- 15 Dec 2024to 15 Jun 2025
- Phase
- Interventional
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 40 to 60 years
- All sexes
- Healthy volunteers accepted
- Adult
Who may be able to join
- Age group 40-60 year
- Both gender male and female
- Stage 2 primary adhesive capsulitis with capsular pattern of restriction (rotation>abduction>flexion)
- Pain in shoulder should be ≤7 on NPRS
- Patient is willing to perform.
Who cannot join
- • Diabetes
- Malignancy
- Infection
- Arthoplasty
- Pregnancy
- Neurological disorders
- Fracture
- Thyroid diseases
Trial locations and contacts
1 site in 1 country. Contact the study team or a site near you to ask about taking part.
Pakistan1 site, 1 recruiting
- Recruiting
Ibne Siena hospital Multan.
Multan Khurd, Punjab Province, 59300
Iqra Fatima, MSOMPT
Rabiya Noor, PHD, 03344355660, rabiya.noor@riphah.edu.pk
About this study
Official title: Effect of Mulligan Mobilization With or Without Niel Asher Technique on Pain, Range of Motion and Disability in Patients With Adhesive Capsulitis
Adhesive capsulitis is a prevalent condition characterized by pain and stiffness in shoulder joint and surrounding muscles shows decrease range and strength in patients with adhesive capsulitis. This study aims to determine the effect of mulligan mobilization with or without Niel Asher technique on pain, range of motion and disability in patients with adhesive capsulitis. This study will be a randomized controlled trial and will be conducted in Ibne-siena Hospital Multan and Multicare physiotherapy clinic. Non-probability convenience sampling will be used to collect the data. Sample size of subjects with age group between 40 to 60 years will be taken. Data will be collected from the patients having present complaint of adhesive capsulitis. Outcome measures used will be Numeric pain rating scale (NPRS) for shoulder pain and SPADI for shoulder disability and Universal Goniometer (GU) for Range of motion. An informed consent will be taken. Subjects will be selected on the basis of inclusion and exclusion criteria. Subjects will be divided into two groups by random number generator table. Both the Groups will receive heating pad, TENS. Group A will receive Mulligan Mobilizations and Neil Asher technique, and Group B will receive Mulligan mobilization and Conventional Treatment. Outcome measures will be measured at baseline and after 4 weeks. Data analysis will be done by SPSS version 26.
- Conditions
- Adhesive Capsulitis
- Being tested
- Mulligan Mobilization and Niel Asher technique, Mulligan Mobilization and Conventional physiotherapy.
- Keywords
- adhesive capsulitis, frozen shoulder, mannual therapy
- Medical subject headings
- Bursitis
What participants receive
What participants receive. In a randomised study each person is assigned to one group by chance.
Mulligan Mobilization and Niel Asher techniqueOther
- Mulligan mobilization technique for shoulder external rotation and abduction as described by Mulligan. 3 sets of 10 repetitions with 1 minute rest between sets, 3 times a week for 4 weeks are performed
- Niel Asher technique provided for 3 sessions a week for 4 weeks
Mulligan Mobilization and Conventional physiotherapy.Other
- Modalities i.e. heating pad and TENS for ten Minutes
- Postural correction exercises / Scapular retraction
- Therapeutic Exercise : Codman' s, finger ladder, wand exercises
- End Range Gleno-humeral joint stretching Both groups will come four times per week for a total of 4 weeks. Pre and post treatment values of both groups will be analyzed.
| Study group | Role | What they receive |
|---|---|---|
| Mulligan Mobilization and Niel Asher technique | Experimental | Shoulder mobilization that includes:
* Mulligan mobilization technique for shoulder external rotation and abduction as described by Mulligan. 3 sets of 10 repetitions with 1 minute rest between sets, 3 times a week for 4 weeks are performed
* Niel Asher technique provided for 3 sessions a week for 4 weeks Receives: Other: Mulligan Mobilization and Niel Asher technique; Other: Mulligan Mobilization and Conventional physiotherapy. |
| Mulligan Mobilization and Conventional physiotherapy. | Active comparator | Group B Will receive Baseline Physical therapy treatment and mulligan mobilization.
Standardized Physiotherapy treatment will be:
* Modalities i.e. heating pad and TENS for ten Minutes
* Postural correction exercises / Scapular retraction
* Therapeutic Exercise : Codman' s, finger ladder, wand exercises
* End Range Gleno-humeral joint stretching Both groups will come four times per week for a total of 4 weeks. Pre and post treatment values of both groups will be analyzed Receives: Other: Mulligan Mobilization and Conventional physiotherapy. |
What is being measured
The primary outcome is the main question the study is designed to answer.
Numerical Pain Rating Scale (NPRS)
Patient level of pain will be assessed using this scale. This scale ranges from 0 to 10. 0 indicates " no pain" and 10 indicates " worst pain" . NPRS have shown high test- retest reliability (r = 0.96 and 0.95, respectively)
Measured: baseline and fourth week
Universal Goniometer (UG)
The range of motion will be measured using universal goniometer that has an inter-rater reliability (ICC2, 2 = 0.79 to 0.92) for shoulder.
Measured: baseline and fourth week
Shoulder disability and shoulder Index SPADI
The Shoulder Pain and Disability Index (SPADI) is a self-administered questionnaire that consists of two dimensions, one for pain and the other for functional activities. The pain dimension consists of five questions regarding the severity of an individual's pain. Functional activities are assessed with eight questions designed to measure the degree of difficulty an individual has with various activities of daily living that require upper- extremity use. The SPADI takes 5 to 10 minutes for a patient to complete and is the only reliable and valid region-specific measure for the shoulder. The reliability coefficient is ICC >0.89 for Shoulder.
Measured: baseline and fourthweek
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted22 May 2025
- Study start15 Dec 2024
- Primary completion15 May 2025 (estimated)
- Study completion15 Jun 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Publications (2)Papers the sponsor has linked to this study.
- Other trials for Adhesive CapsulitisStudies of the same condition, open and under way.
- More trials run by Riphah International UniversityThe sponsor's other registered studies.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Interventional
- Phase
- Phase N/A
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind
- Who is masked
- Participant
- Enrolment
- 42 participants (estimated)
Sponsor and investigators
- Lead sponsor
- Riphah International University
- Sponsor type
- University, hospital or other
- Responsible party
- Sponsor
- Investigators
- Rabiya Noor, PHD, Principal investigator, Riphah International University
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06985836
- Sponsor's protocol ID
- REC/RCR & AHS/24/0180
- Status last verified
- May 2025
- First submitted
- 15 May 2025
- Last updated
- 22 May 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
- Individual data sharing
- No
Publications
Doner G, Guven Z, Atalay A, Celiker R. Evalution of Mulligan's technique for adhesive capsulitis of the shoulder. J Rehabil Med. 2013 Jan;45(1):87-91. doi: 10.2340/16501977-1064.
PubMed 23037929Childs JD, Piva SR, Fritz JM. Responsiveness of the numeric pain rating scale in patients with low back pain. Spine (Phila Pa 1976). 2005 Jun 1;30(11):1331-4. doi: 10.1097/01.brs.0000164099.92112.29.
PubMed 15928561
Study at a glance
From the registry record, last updated by the sponsor on 22 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Effect of Mulligan Mobilization With or Without Niel Asher Technique on Pain, Range of Motion and Disability in Patients With Adhesive Capsulitis
- ClinicalTrials.gov ID
- NCT06985836
- Acronym / sponsor ID
- REC/RCR & AHS/24/0180
- Conditions
- Adhesive Capsulitis
- Keywords
- adhesive capsulitis, frozen shoulder, mannual therapy
- Study type
- Interventional
- Recruitment status
- Recruiting
- Enrolment
- 42 participants (estimated)
- Lead sponsor
- Riphah International UniversityUniversity, hospital or other
- Study start
- 15 Dec 2024 (actual)
- Primary completion
- 15 May 2025 (estimated)
- Study completion
- 15 Jun 2025 (estimated)
- First posted
- 22 May 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
Adhesive capsulitis is a prevalent condition characterized by pain and stiffness in shoulder joint and surrounding muscles shows decrease range and strength in patients with adhesive capsulitis. This study aims to determine the effect of mulligan mobilization with or without Niel Asher technique on pain, range of motion and disability in patients with adhesive capsulitis. This study will be a randomized controlled trial and will be conducted in Ibne-siena Hospital Multan and Multicare physiotherapy clinic. Non-probability convenience sampling will be used to collect the data. Sample size of subjects with age group between 40 to 60 years will be taken. Data will be collected from the patients having present complaint of adhesive capsulitis. Outcome measures used will be Numeric pain rating scale (NPRS) for shoulder pain and SPADI for shoulder disability and Universal Goniometer (GU) for Range of motion. An informed consent will be taken. Subjects will be selected on the basis of inclusion and exclusion criteria. Subjects will be divided into two groups by random number generator table. Both the Groups will receive heating pad, TENS. Group A will receive Mulligan Mobilizations and Neil Asher technique, and Group B will receive Mulligan mobilization and Conventional Treatment. Outcome measures will be measured at baseline and after 4 weeks. Data analysis will be done by SPSS version 26.
Study design
- Primary purpose
- Treatment
- Allocation
- Randomised
- Intervention model
- Parallel groups
- Masking
- Single blind (participant)
- Number of arms
- 2
| Arm | Type | Receives |
|---|---|---|
| Mulligan Mobilization and Niel Asher technique | Experimental | Other: Mulligan Mobilization and Niel Asher technique, Other: Mulligan Mobilization and Conventional physiotherapy.Shoulder mobilization that includes: * Mulligan mobilization technique for shoulder external rotation and abduction as described by Mulligan. 3 sets of 10 repetitions with 1 minute rest between sets, 3 times a week for 4 weeks are performed * Niel Asher technique provided for 3 sessions a week for 4 weeks |
| Mulligan Mobilization and Conventional physiotherapy. | Active comparator | Other: Mulligan Mobilization and Conventional physiotherapy.Group B Will receive Baseline Physical therapy treatment and mulligan mobilization. Standardized Physiotherapy treatment will be: * Modalities i.e. heating pad and TENS for ten Minutes * Postural correction exercises / Scapular retraction * Therapeutic Exercise : Codman' s, finger ladder, wand exercises * End Range Gleno-humeral joint stretching Both groups will come four times per week for a total of 4 weeks. Pre and post treatment values of both groups will be analyzed |
Who may qualify
- Ages
- 40 to 60 years
- Sex
- All
- Healthy volunteers
- Accepted
- Age groups
- Adult
Key inclusion criteria (5 listed)
- Age group 40-60 year
- Both gender male and female
- Stage 2 primary adhesive capsulitis with capsular pattern of restriction (rotation>abduction>flexion)
- Pain in shoulder should be ≤7 on NPRS
- Patient is willing to perform.
Key exclusion criteria (8 listed)
- • Diabetes
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Interventions
| Intervention | Type | Arms |
|---|---|---|
| Mulligan Mobilization and Niel Asher technique* Mulligan mobilization technique for shoulder external rotation and abduction as described by Mulligan. 3 sets of 10 repetitions with 1 minute rest between sets, 3 times a week for 4 weeks are performed * Niel Asher technique provided for 3 sessions a week for 4 weeks | Other | Mulligan Mobilization and Niel Asher technique |
| Mulligan Mobilization and Conventional physiotherapy.* Modalities i.e. heating pad and TENS for ten Minutes * Postural correction exercises / Scapular retraction * Therapeutic Exercise : Codman' s, finger ladder, wand exercises * End Range Gleno-humeral joint stretching Both groups will come four times per week for a total of 4 weeks. Pre and post treatment values of both groups will be analyzed. | Other | Mulligan Mobilization and Conventional physiotherapy., Mulligan Mobilization and Niel Asher technique |
Primary outcome
Numerical Pain Rating Scale (NPRS)
Time frame: baseline and fourth week
Patient level of pain will be assessed using this scale. This scale ranges from 0 to 10. 0 indicates " no pain" and 10 indicates " worst pain" . NPRS have shown high test- retest reliability (r = 0.96 and 0.95, respectively)
Universal Goniometer (UG)
Time frame: baseline and fourth week
The range of motion will be measured using universal goniometer that has an inter-rater reliability (ICC2, 2 = 0.79 to 0.92) for shoulder.
Shoulder disability and shoulder Index SPADI
Time frame: baseline and fourthweek
The Shoulder Pain and Disability Index (SPADI) is a self-administered questionnaire that consists of two dimensions, one for pain and the other for functional activities. The pain dimension consists of five questions regarding the severity of an individual's pain. Functional activities are assessed with eight questions designed to measure the degree of difficulty an individual has with various activities of daily living that require upper- extremity use. The SPADI takes 5 to 10 minutes for a patient to complete and is the only reliable and valid region-specific measure for the shoulder. The reliability coefficient is ICC >0.89 for Shoulder.
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 22 May 2025.
- Background: PubMed 23037929Doner G, Guven Z, Atalay A, Celiker R. Evalution of Mulligan's technique for adhesive capsulitis of the shoulder. J Rehabil Med. 2013 Jan;45(1):87-91. doi: 10.2340/16501977-1064.
- Background: PubMed 15928561Childs JD, Piva SR, Fritz JM. Responsiveness of the numeric pain rating scale in patients with low back pain. Spine (Phila Pa 1976). 2005 Jun 1;30(11):1331-4. doi: 10.1097/01.brs.0000164099.92112.29.
- Individual participant dataSharing planned: No
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Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part.
Rabiya Noor, PHD principal investigator
Riphah International University
1 site in 1 country: see every site and its status.
Questions about this trial
What is this clinical trial studying?
A study testing Mulligan Mobilization and Niel Asher technique and Mulligan Mobilization and Conventional physiotherapy. in people with Adhesive Capsulitis, run by Riphah International University at 1 site in Pakistan.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 5 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: looking for participants now, as of the sponsor's last update on 22 May 2025. Status can change between updates, so confirm with the study contact before making plans.
Where is the study taking place?
The record lists 1 site in Pakistan. Whether a site is taking part right now should be confirmed with that site. See every site.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
Contact Iqbal Tariq, PHD (03338236752, Iqbal.tariq@riphah.edu.pk), or a site near the patient. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Numerical Pain Rating Scale (NPRS) (time frame: baseline and fourth week). The study lists 3 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
On the ClinicalTrials.gov record for NCT06985836, which also lists 2 linked publications.
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 22 May 2025.