Juxtarenal AneurysmsNCT06988345
Juxtarenal Aortic Aneurysm
An observational study of Juxtarenal Aneurysms and Open Repair, run by University Hospital Muenster.
Trial summary
All patients with a juxtarenal abdominal aortic aneurysm who underwent open aneurysm therapy between January 2010 and July 2020 were included retrospectively. Read more about this study
- Who is it for?
- Ages 18 years and older
- Conditions the study is for
- Juxtarenal Aneurysms, Open Repair
- How many people
- 200 participants
- Where
- No sites listed yet
- Study dates
- 1 Jan 2010to 31 Dec 2025
- Phase
- Observational
- Are there results?
- Not yet: the study is under way
Key requirements
Who can take part, as listed by the sponsor. Only the study team can confirm whether you are eligible, so take this list to your doctor.
- Ages 18 years and older
- All sexes
- No healthy volunteers
- Adult, Older adult
Study population: All patients with a juxtarenal aneurysm who fulfill the inclusion criteria or do not fulfill the exclusion criteria may be included in this study
Who may be able to join
- Patients with a juxtarenal aneurysm (defined as infrarenal neck <10mm and clamping above at least one renal artery [31592091])
- Open therapy with infrarenal (Anschluss)
- >18 years
Who cannot join
- Patients with an anastomosis above the renal arteries (e.g. including bypass to a renal artery)
- Patients with supravisceral clamping
- Patients with reconstruction of the aorta in the suprarenal area
- Patients with connective tissue diseases (e.g. Marfan syndrome or Ehler Danlos syndrome)
- Post-dissection aneurysms
- Infected aneurysms
- Conversions after endovascular therapy
- Inflammatory aneurysms
About this study
Official title: Outcome Juxtarenal Aortic Aneurysm After Open Repair
All patients with a juxtarenal abdominal aortic aneurysm who underwent open aneurysm therapy between January 2010 and July 2020 were included retrospectively.
- Conditions
- Juxtarenal Aneurysms, Open Repair
What is being measured
The primary outcome is the main question the study is designed to answer.
Mortality
Mortality after 30 days postop
Measured: 30 days after intervention
Acute renal failure
Acute renal failure postoperatively, defined by KDIGO criteria of AKI [22890468]
Measured: 30 days after intervention
Secondary outcomes (5)
Dialysis
Permanent dialysis required
Measured: during Follow up period, checked every year
Reinterventions
Rates of Reinterventions
Measured: during Follow up period, checked every year
Mortality
Overall mortality
Measured: during Follow up period (up to 13 years)
Aneurysm-related Mortality
Aneurysm-related Mortality
Measured: during Follow up period (up to 13 years)
Post-operative complication rates
Post-operative complication rates:
- cardiac
- pulmonal
- mesenterial
- neurological
- access-associated
- re-intervention
Measured: During Follow-up period (up to 13 years)
Timeline
From the start of the study to its completion; the mark is today. Estimated dates are the sponsor’s plan.
- First posted23 May 2025
- Study start1 Jan 2010
- Primary completion31 Dec 2020
- Study completion31 Dec 2025 (estimated)
Resources
- Official record on ClinicalTrials.govThe registry entry this page is built from, with its full change history.
- Other trials for Juxtarenal AneurysmsStudies of the same condition, open and under way.
- What the trial phases meanHow a treatment moves from first tests in people to approval.
More details
For doctors and researchers: how the study is designed, who runs it, and its registry IDs.
Study design
- Study type
- Observational
- Observational model
- Other
- Time perspective
- Retrospective
- Enrolment
- 200 participants (estimated)
Sponsor and investigators
- Lead sponsor
- University Hospital Muenster
- Sponsor type
- University, hospital or other
- Collaborators
- University Hospital Augsburg, University Hospital, Aachen, Goethe University, University Hospital Heidelberg, University Hospital Regensburg, University of Hamburg-Eppendorf
- Responsible party
- Principal investigator, Univ.-Prof. Dr. med. Alexander Oberhuber, University Hospital Muenster
IDs, dates and publications
- ClinicalTrials.gov ID
- NCT06988345
- Sponsor's protocol ID
- 2023-641-f-S
- Status last verified
- May 2025
- First submitted
- 20 Nov 2024
- Last updated
- 23 May 2025
- Results posted
- No
- Data monitoring committee
- No
- FDA-regulated drug
- No
- FDA-regulated device
- No
Study at a glance
From the registry record, last updated by the sponsor on 23 May 2025. Recruitment status is as the sponsor reported it: confirm with the study team.
- Official title
- Outcome Juxtarenal Aortic Aneurysm After Open Repair
- ClinicalTrials.gov ID
- NCT06988345
- Acronym / sponsor ID
- 2023-641-f-S
- Conditions
- Juxtarenal Aneurysms, Open Repair
- Study type
- Observational
- Recruitment status
- Active, not recruiting
- Enrolment
- 200 participants (estimated)
- Lead sponsor
- University Hospital MuensterUniversity, hospital or other
- Collaborators
- University Hospital Augsburg, University Hospital, Aachen, Goethe University, University Hospital Heidelberg, University Hospital Regensburg, University of Hamburg-Eppendorf
- Study start
- 1 Jan 2010 (actual)
- Primary completion
- 31 Dec 2020 (actual)
- Study completion
- 31 Dec 2025 (estimated)
- First posted
- 23 May 2025 (actual)
- Results
- Not posted in the source record
Clinical summary
The research question as the sponsor registered it. This describes what the study plans to test, not what it found.
All patients with a juxtarenal abdominal aortic aneurysm who underwent open aneurysm therapy between January 2010 and July 2020 were included retrospectively.
Study design
- Observational model
- Other
- Time perspective
- Retrospective
Who may qualify
- Ages
- 18 years and older
- Sex
- All
- Healthy volunteers
- Not accepted
- Age groups
- Adult, Older adult
- Study population
- All patients with a juxtarenal aneurysm who fulfill the inclusion criteria or do not fulfill the exclusion criteria may be included in this study
Key inclusion criteria (3 listed)
- Patients with a juxtarenal aneurysm (defined as infrarenal neck <10mm and clamping above at least one renal artery [31592091])
- Open therapy with infrarenal (Anschluss)
- >18 years
Key exclusion criteria (8 listed)
- Patients with an anastomosis above the renal arteries (e.g. including bypass to a renal artery)
- Patients with supravisceral clamping
- Patients with reconstruction of the aorta in the suprarenal area
- Patients with connective tissue diseases (e.g. Marfan syndrome or Ehler Danlos syndrome)
- Post-dissection aneurysms
Eligibility is decided by the study team after screening; this overview does not establish that a patient qualifies. Full inclusion and exclusion criteria.
Primary outcome
Mortality
Time frame: 30 days after intervention
Mortality after 30 days postop
Acute renal failure
Time frame: 30 days after intervention
Acute renal failure postoperatively, defined by KDIGO criteria of AKI [22890468]
5 secondary outcomes
Dialysis
Time frame: during Follow up period, checked every year
Reinterventions
Time frame: during Follow up period, checked every year
Mortality
Time frame: during Follow up period (up to 13 years)
Aneurysm-related Mortality
Time frame: during Follow up period (up to 13 years)
Post-operative complication rates
Time frame: During Follow-up period (up to 13 years)
Results and safety
This study is still under way. Results are not available in the source record yet.
Research links
- Official record on ClinicalTrials.govLast updated by the sponsor 23 May 2025.
Related trials for Juxtarenal Aneurysms
Recruiting
Zenith® Fenestrated+ Clinical Study
Aortic Aneurysm, Abdominal, Juxtarenal Aortic Aneurysm
Recruiting
Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Juxtarenal Aortic Aneurysms
Technical Sucess, Freedom From Type I and III Endoleaks at 12 Months
Not yet recruiting
Evaluation of the Efficacy of Ischemic Preconditioning to Protect Against Acute Kidney Injury After Open Surgery for Juxtarenal Abdominal Aortic Aneurysm
Aneurysm Aortic
Active, not recruitingObservational study
Endurant CHevAr New Indication Trial: ENCHANT
AAA - Abdominal Aortic Aneurysm
Recruiting
University of Utah PS-IDE: Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Juxtarenal Aortic Aneurysms
Juxtarenal Abdominal Aortic Aneurysm
Referral and contact
AzTrials does not enrol participants or take referrals. Contact the study team or a site listed below; they decide who can take part. This study is not recruiting at the moment.
The record lists no contact. Use the official record to reach the sponsor.
Questions about this trial
What is this clinical trial studying?
An observational study of Juxtarenal Aneurysms and Open Repair, run by University Hospital Muenster.
The full registered description is in the About this study section and the official record.
Who may be eligible to take part?
The sponsor lists 3 inclusion and 8 exclusion criteria. Eligibility is decided by the study team after screening, so read the full criteria and contact a listed site.
Is this clinical trial currently recruiting?
The record says: under way, not looking for participants, as of the sponsor's last update on 23 May 2025. Status can change between updates, so confirm with the study contact before making plans.
What are the possible benefits and risks?
They depend on the study and the treatment, and no study can promise a benefit. The study team explains the known risks during informed consent, before anyone joins; the record itself does not list them.
Are results available for this study?
This study is still under way. Results are not available in the source record yet.
How can a doctor refer a patient or contact the research team?
The record lists no contact. The official record names the sponsor, who can be asked directly. AzTrials does not enrol participants or take referrals.
What does the primary outcome measure?
Mortality (time frame: 30 days after intervention). The study lists 2 primary outcomes in all. It is what the study was designed to measure, not a finding.
Where can I read the original study information?
Does a listing mean the treatment is approved or proven to work?
No. A listing means the study is registered. It does not show that the treatment is safe, works, or is approved by a regulator.
How often is this information updated?
AzTrials copies changed records from ClinicalTrials.gov every night and reloads the whole registry every week. The sponsor last updated this record on 23 May 2025.